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Items: 1 to 50 of 63

1.

Broad application and optimization of a single wash-step for integrated endotoxin depletion during protein purification.

Koziel D, Michaelis U, Kruse T.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 1;1091:101-107. doi: 10.1016/j.jchromb.2018.05.029. Epub 2018 May 21.

PMID:
29860213
2.

Proof of concept study with an HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform.

Singer J, Manzano-Szalai K, Fazekas J, Thell K, Bentley-Lukschal A, Stremnitzer C, Roth-Walter F, Weghofer M, Ritter M, Pino Tossi K, Hörer M, Michaelis U, Jensen-Jarolim E.

Oncoimmunology. 2016 Apr 21;5(7):e1171446. doi: 10.1080/2162402X.2016.1171446. eCollection 2016 Jul.

3.

Polarity Protein Scrib Facilitates Endothelial Inflammatory Signaling.

Kruse C, Kurz AR, Pálfi K, Humbert PO, Sperandio M, Brandes RP, Fork C, Michaelis UR.

Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):1954-62. doi: 10.1161/ATVBAHA.115.305678. Epub 2015 Jul 23.

PMID:
26205961
4.

Reprogramming of myeloid angiogenic cells by Bartonella henselae leads to microenvironmental regulation of pathological angiogenesis.

O'Rourke F, Mändle T, Urbich C, Dimmeler S, Michaelis UR, Brandes RP, Flötenmeyer M, Döring C, Hansmann ML, Lauber K, Ballhorn W, Kempf VA.

Cell Microbiol. 2015 Oct;17(10):1447-63. doi: 10.1111/cmi.12447. Epub 2015 May 19.

PMID:
25857345
5.

Adeno-associated virus-like particles as new carriers for B-cell vaccines: testing immunogenicity and safety in BALB/c mice.

Manzano-Szalai K, Thell K, Willensdorfer A, Weghofer M, Pfanzagl B, Singer J, Ritter M, Stremnitzer C, Flaschberger I, Michaelis U, Jensen-Jarolim E.

Viral Immunol. 2014 Nov;27(9):438-48. doi: 10.1089/vim.2014.0059. Epub 2014 Sep 23.

6.

Mechanisms of endothelial cell migration.

Michaelis UR.

Cell Mol Life Sci. 2014 Nov;71(21):4131-48. doi: 10.1007/s00018-014-1678-0. Epub 2014 Jul 20. Review.

PMID:
25038776
7.

Phase I/II clinical study on safety and antivascular effects of paclitaxel encapsulated in cationic liposomes for targeted therapy in advanced head and neck cancer.

Strieth S, Dunau C, Michaelis U, Jäger L, Gellrich D, Wollenberg B, Dellian M.

Head Neck. 2014 Jul;36(7):976-84. doi: 10.1002/hed.23397. Epub 2013 Dec 11.

PMID:
23733258
8.

[Optimising rehabilitative care for people with major amputation - a qualitative study].

Gaidys U, Michaelis U.

Pflege. 2013 Feb;26(1):31-41. doi: 10.1024/1012-5302/a000261. German.

PMID:
23384843
9.

The polarity protein Scrib is essential for directed endothelial cell migration.

Michaelis UR, Chavakis E, Kruse C, Jungblut B, Kaluza D, Wandzioch K, Manavski Y, Heide H, Santoni MJ, Potente M, Eble JA, Borg JP, Brandes RP.

Circ Res. 2013 Mar 15;112(6):924-34. doi: 10.1161/CIRCRESAHA.112.300592. Epub 2013 Jan 29.

PMID:
23362312
10.
11.

Phase I clinical study of vascular targeting fluorescent cationic liposomes in head and neck cancer.

Strieth S, Dunau C, Kolbow K, Knuechel R, Michaelis U, Ledderose H, Eichhorn ME, Strelczyk D, Tschiesner U, Wollenberg B, Dellian M.

Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1481-7. doi: 10.1007/s00405-012-2185-2. Epub 2012 Sep 27.

PMID:
23015197
12.

Development of AAVLP(HPV16/31L2) particles as broadly protective HPV vaccine candidate.

Nieto K, Weghofer M, Sehr P, Ritter M, Sedlmeier S, Karanam B, Seitz H, Müller M, Kellner M, Hörer M, Michaelis U, Roden RB, Gissmann L, Kleinschmidt JA.

PLoS One. 2012;7(6):e39741. doi: 10.1371/journal.pone.0039741. Epub 2012 Jun 27.

13.

In vivo imaging of choroidal angiogenesis using fluorescence-labeled cationic liposomes.

Hua J, Gross N, Schulze B, Michaelis U, Bohnenkamp H, Guenzi E, Hansen LL, Martin G, Agostini HT.

Mol Vis. 2012;18:1045-54. Epub 2012 Apr 26.

14.

Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.

Schröder K, Zhang M, Benkhoff S, Mieth A, Pliquett R, Kosowski J, Kruse C, Luedike P, Michaelis UR, Weissmann N, Dimmeler S, Shah AM, Brandes RP.

Circ Res. 2012 Apr 27;110(9):1217-25. doi: 10.1161/CIRCRESAHA.112.267054. Epub 2012 Mar 27.

PMID:
22456182
15.

Chemotherapy-associated angiogenesis in neuroblastoma tumors.

Michaelis M, Hinsch N, Michaelis UR, Rothweiler F, Simon T, ilhelm Doerr HW, Cinatl J, Cinatl J Jr.

Am J Pathol. 2012 Apr;180(4):1370-7. doi: 10.1016/j.ajpath.2011.12.011. Epub 2012 Jan 27.

PMID:
22285670
16.

Hepatocyte growth factor induces a proangiogenic phenotype and mobilizes endothelial progenitor cells by activating Nox2.

Schröder K, Schütz S, Schlöffel I, Bätz S, Takac I, Weissmann N, Michaelis UR, Koyanagi M, Brandes RP.

Antioxid Redox Signal. 2011 Aug 15;15(4):915-23. doi: 10.1089/ars.2010.3533. Epub 2011 Apr 5.

PMID:
21050133
17.

Vascular targeting by EndoTAG-1 enhances therapeutic efficacy of conventional chemotherapy in lung and pancreatic cancer.

Eichhorn ME, Ischenko I, Luedemann S, Strieth S, Papyan A, Werner A, Bohnenkamp H, Guenzi E, Preissler G, Michaelis U, Jauch KW, Bruns CJ, Dellian M.

Int J Cancer. 2010 Mar 1;126(5):1235-45. doi: 10.1002/ijc.24846.

18.

Paclitaxel encapsulated in cationic liposomes: a new option for neovascular targeting for the treatment of prostate cancer.

Bode C, Trojan L, Weiss C, Kraenzlin B, Michaelis U, Teifel M, Alken P, Michel MS.

Oncol Rep. 2009 Aug;22(2):321-6.

PMID:
19578772
19.

Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis.

Webler AC, Michaelis UR, Popp R, Barbosa-Sicard E, Murugan A, Falck JR, Fisslthaler B, Fleming I.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1292-301. doi: 10.1152/ajpcell.00230.2008. Epub 2008 Sep 11.

20.

Paclitaxel encapsulated in cationic liposomes increases tumor microvessel leakiness and improves therapeutic efficacy in combination with Cisplatin.

Strieth S, Eichhorn ME, Werner A, Sauer B, Teifel M, Michaelis U, Berghaus A, Dellian M.

Clin Cancer Res. 2008 Jul 15;14(14):4603-11. doi: 10.1158/1078-0432.CCR-07-4738.

21.

Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4.

Webler AC, Popp R, Korff T, Michaelis UR, Urbich C, Busse R, Fleming I.

Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1123-9. doi: 10.1161/ATVBAHA.107.161190. Epub 2008 Mar 13.

PMID:
18340006
22.

Role of cytochrome P450 2C epoxygenases in hypoxia-induced cell migration and angiogenesis in retinal endothelial cells.

Michaelis UR, Xia N, Barbosa-Sicard E, Falck JR, Fleming I.

Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1242-7. doi: 10.1167/iovs.07-1087.

PMID:
18326754
23.

Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomes.

Strieth S, Nussbaum CF, Eichhorn ME, Fuhrmann M, Teifel M, Michaelis U, Berghaus A, Dellian M.

Int J Cancer. 2008 Jan 15;122(2):452-60.

24.

Validation of the Gross Motor Function Measure for use in children and adolescents with traumatic brain injuries.

Linder-Lucht M, Othmer V, Walther M, Vry J, Michaelis U, Stein S, Weissenmayer H, Korinthenberg R, Mall V; Gross Motor Function Measure-Traumatic Brain Injury Study Group.

Pediatrics. 2007 Oct;120(4):e880-6.

PMID:
17908744
25.

Cationic lipid complexed camptothecin (EndoTAG-2) improves antitumoral efficacy by tumor vascular targeting.

Eichhorn ME, Luedemann S, Strieth S, Papyan A, Ruhstorfer H, Haas H, Michaelis U, Sauer B, Teifel M, Enders G, Brix G, Jauch KW, Bruns CJ, Dellian M.

Cancer Biol Ther. 2007 Jun;6(6):920-9. Epub 2007 Mar 26.

PMID:
17534143
26.

Extraction and quantification of the cationic lipid 1,2-dioleoyl-3-trimethylammonium propane from human plasma.

Koeber R, Pappas A, Michaelis U, Schulze B.

Anal Biochem. 2007 Apr 1;363(1):157-9. Epub 2007 Jan 26. No abstract available.

PMID:
17291442
27.

[No one should prevent one from drinking a little glass in someone's honor].

Michaelis U, Jung A.

Pflege Aktuell. 2006 Feb;60:68-71. German. No abstract available.

PMID:
16502784
28.

From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling.

Michaelis UR, Fleming I.

Pharmacol Ther. 2006 Sep;111(3):584-95. Epub 2005 Dec 27. Review.

PMID:
16380164
29.

Paclitaxel encapsulated in cationic lipid complexes (MBT-0206) impairs functional tumor vascular properties as detected by dynamic contrast enhanced magnetic resonance imaging.

Eichhorn ME, Becker S, Strieth S, Werner A, Sauer B, Teifel M, Ruhstorfer H, Michaelis U, Griebel J, Brix G, Jauch KW, Dellian M.

Cancer Biol Ther. 2006 Jan;5(1):89-96. Epub 2006 Jan 22.

PMID:
16357513
30.

Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis.

Michaelis UR, Fisslthaler B, Barbosa-Sicard E, Falck JR, Fleming I, Busse R.

J Cell Sci. 2005 Dec 1;118(Pt 23):5489-98. Epub 2005 Nov 15.

31.

Valproic acid induces extracellular signal-regulated kinase 1/2 activation and inhibits apoptosis in endothelial cells.

Michaelis M, Suhan T, Michaelis UR, Beek K, Rothweiler F, Tausch L, Werz O, Eikel D, Zörnig M, Nau H, Fleming I, Doerr HW, Cinatl J Jr.

Cell Death Differ. 2006 Mar;13(3):446-53.

32.

Is troponin I gene therapy effective for osteosarcoma treatment? Study on a human-like orthotopic rat model.

Dutour A, Rabinovich-Chable H, Kaletta C, Michaelis U, Fiorenza F, Sturtz F, Rigaud M.

Anticancer Res. 2004 Nov-Dec;24(6):3977-82.

33.

Cytochrome P4502C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells.

Michaelis UR, Falck JR, Schmidt R, Busse R, Fleming I.

Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):321-6. Epub 2004 Nov 29.

PMID:
15569819
34.

Protamine enhances uptake of cationic liposomes in angiogenic microvessels.

Eichhorn ME, Strieth S, Krasnici S, Sauer B, Teifel M, Michaelis U, Naujoks K, Dellian M.

Angiogenesis. 2004;7(2):133-41.

PMID:
15516834
35.

The accuracy of free-hand cup positioning--a CT based measurement of cup placement in 105 total hip arthroplasties.

Saxler G, Marx A, Vandevelde D, Langlotz U, Tannast M, Wiese M, Michaelis U, Kemper G, Grützner PA, Steffen R, von Knoch M, Holland-Letz T, Bernsmann K.

Int Orthop. 2004 Aug;28(4):198-201. Epub 2004 May 15.

36.

[Cup placement in hip replacement surgery -- A comparison of free-hand and computer assisted cup placement in total hip arthroplasty -- a multi-center study].

Saxler G, Marx A, Vandevelde D, Langlotz U, Tannast M, Wiese M, Michaelis U, Kemper G, Grützner PA, Steffen R, von Knoch M, Holland-Letz T, Bernsmann K.

Z Orthop Ihre Grenzgeb. 2004 May-Jun;142(3):286-91. German.

PMID:
15249999
37.

Neovascular targeting chemotherapy: encapsulation of paclitaxel in cationic liposomes impairs functional tumor microvasculature.

Strieth S, Eichhorn ME, Sauer B, Schulze B, Teifel M, Michaelis U, Dellian M.

Int J Cancer. 2004 May 20;110(1):117-24.

38.

Valproic acid inhibits angiogenesis in vitro and in vivo.

Michaelis M, Michaelis UR, Fleming I, Suhan T, Cinatl J, Blaheta RA, Hoffmann K, Kotchetkov R, Busse R, Nau H, Cinatl J Jr.

Mol Pharmacol. 2004 Mar;65(3):520-7.

PMID:
14978230
39.

Neovascular targeting therapy: paclitaxel encapsulated in cationic liposomes improves antitumoral efficacy.

Schmitt-Sody M, Strieth S, Krasnici S, Sauer B, Schulze B, Teifel M, Michaelis U, Naujoks K, Dellian M.

Clin Cancer Res. 2003 Jun;9(6):2335-41.

40.

Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels.

Krasnici S, Werner A, Eichhorn ME, Schmitt-Sody M, Pahernik SA, Sauer B, Schulze B, Teifel M, Michaelis U, Naujoks K, Dellian M.

Int J Cancer. 2003 Jul 1;105(4):561-7.

41.

Paclitaxel encapsulated in cationic liposomes diminishes tumor angiogenesis and melanoma growth in a "humanized" SCID mouse model.

Kunstfeld R, Wickenhauser G, Michaelis U, Teifel M, Umek W, Naujoks K, Wolff K, Petzelbauer P.

J Invest Dermatol. 2003 Mar;120(3):476-82.

42.

Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR).

Michaelis UR, Fisslthaler B, Medhora M, Harder D, Fleming I, Busse R.

FASEB J. 2003 Apr;17(6):770-2. Epub 2003 Feb 5.

PMID:
12586744
43.

Cytochrome P450 epoxygenases and vascular tone: novel role for HMG-CoA reductase inhibitors in the regulation of CYP 2C expression.

Fisslthaler B, Michaelis UR, Randriamboavonjy V, Busse R, Fleming I.

Biochim Biophys Acta. 2003 Feb 17;1619(3):332-9. Review.

PMID:
12573493
44.

Cytochrome P450 2C expression and EDHF-mediated relaxation in porcine coronary arteries is increased by cortisol.

Bauersachs J, Christ M, Ertl G, Michaelis UR, Fisslthaler B, Busse R, Fleming I.

Cardiovasc Res. 2002 Jun;54(3):669-75.

PMID:
12031713
46.

Medium-term functional benefits in children with cerebral palsy treated with botulinum toxin type A: 1-year follow-up using gross motor function measure.

Linder M, Schindler G, Michaelis U, Stein S, Kirschner J, Mall V, Berweck S, Korinthenberg R, Heinen F.

Eur J Neurol. 2001 Nov;8 Suppl 5:120-6.

PMID:
11851740
47.

Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase.

Fisslthaler B, Popp R, Michaelis UR, Kiss L, Fleming I, Busse R.

Hypertension. 2001 Dec 1;38(6):1427-32.

PMID:
11751730
48.

The coronary endothelium-derived hyperpolarizing factor (EDHF) stimulates multiple signalling pathways and proliferation in vascular cells.

Fleming I, Fisslthaler B, Michaelis UR, Kiss L, Popp R, Busse R.

Pflugers Arch. 2001 Jul;442(4):511-8.

PMID:
11510882
49.

Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries.

Fleming I, Michaelis UR, Bredenkötter D, Fisslthaler B, Dehghani F, Brandes RP, Busse R.

Circ Res. 2001 Jan 19;88(1):44-51.

PMID:
11139472
50.

Evaluation of botulinum toxin A therapy in children with adductor spasm by gross motor function measure.

Mall V, Heinen F, Kirschner J, Linder M, Stein S, Michaelis U, Bernius P, Lane M, Korinthenberg R.

J Child Neurol. 2000 Apr;15(4):214-7.

PMID:
10805185

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