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Items: 1 to 50 of 63

1.

Programmed Cell Death in the Evolutionary Race against Bacterial Virulence Factors.

Lacey CA, Miao EA.

Cold Spring Harb Perspect Biol. 2019 Sep 9. pii: a036459. doi: 10.1101/cshperspect.a036459. [Epub ahead of print]

PMID:
31501197
2.

NLRP1 - One NLR to guard them all.

Lacey CA, Miao EA.

EMBO J. 2019 Jul 1;38(13):e102494. doi: 10.15252/embj.2019102494. Epub 2019 Jun 12.

PMID:
31268605
3.

A licence to kill during inflammation.

Nozaki K, Miao EA.

Nature. 2019 Jun;570(7761):316-317. doi: 10.1038/d41586-019-01764-9. No abstract available.

PMID:
31213677
4.

Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice.

Fan TJ, Tchaptchet SY, Arsene D, Mishima Y, Liu B, Sartor RB, Carroll IM, Miao EA, Fodor AA, Hansen JJ.

Inflamm Bowel Dis. 2018 Oct 12;24(11):2394-2403. doi: 10.1093/ibd/izy244.

5.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

6.

Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock.

Hagar JA, Edin ML, Lih FB, Thurlow LR, Koller BH, Cairns BA, Zeldin DC, Miao EA.

J Immunol. 2017 Nov 15;199(10):3634-3643. doi: 10.4049/jimmunol.1700820. Epub 2017 Oct 16.

7.

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

Cheng KT, Xiong S, Ye Z, Hong Z, Di A, Tsang KM, Gao X, An S, Mittal M, Vogel SM, Miao EA, Rehman J, Malik AB.

J Clin Invest. 2017 Nov 1;127(11):4124-4135. doi: 10.1172/JCI94495. Epub 2017 Oct 9.

8.

Dietary Salt Exacerbates Experimental Colitis.

Tubbs AL, Liu B, Rogers TD, Sartor RB, Miao EA.

J Immunol. 2017 Aug 1;199(3):1051-1059. doi: 10.4049/jimmunol.1700356. Epub 2017 Jun 21.

9.

Gasdermins: Effectors of Pyroptosis.

Kovacs SB, Miao EA.

Trends Cell Biol. 2017 Sep;27(9):673-684. doi: 10.1016/j.tcb.2017.05.005. Epub 2017 Jun 12. Review.

10.

Programmed cell death as a defence against infection.

Jorgensen I, Rayamajhi M, Miao EA.

Nat Rev Immunol. 2017 Mar;17(3):151-164. doi: 10.1038/nri.2016.147. Epub 2017 Jan 31. Review.

11.

Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.

Choi HW, Bowen SE, Miao Y, Chan CY, Miao EA, Abrink M, Moeser AJ, Abraham SN.

Immunity. 2016 Dec 20;45(6):1258-1269. doi: 10.1016/j.immuni.2016.11.003. Epub 2016 Dec 6.

12.

IL-1β, IL-18, and eicosanoids promote neutrophil recruitment to pore-induced intracellular traps following pyroptosis.

Jorgensen I, Lopez JP, Laufer SA, Miao EA.

Eur J Immunol. 2016 Dec;46(12):2761-2766. doi: 10.1002/eji.201646647. Epub 2016 Oct 19.

13.

Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis.

Jorgensen I, Zhang Y, Krantz BA, Miao EA.

J Exp Med. 2016 Sep 19;213(10):2113-28. doi: 10.1084/jem.20151613. Epub 2016 Aug 29.

14.

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.

Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, Miao EA, McBride JW, Kotsyfakis M, Pedra JH.

PLoS Pathog. 2016 Aug 2;12(8):e1005803. doi: 10.1371/journal.ppat.1005803. eCollection 2016 Aug.

15.

Down with doublespeak: NAIP/NLRC4 inflammasomes get specific.

Aachoui Y, Miao EA.

J Exp Med. 2016 May 2;213(5):646. doi: 10.1084/jem.2135insight1. No abstract available.

16.

Reassessing the Evolutionary Importance of Inflammasomes.

Maltez VI, Miao EA.

J Immunol. 2016 Feb 1;196(3):956-62. doi: 10.4049/jimmunol.1502060. Review.

17.

Corrigendum: The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3.

Rayamajhi M, Miao EA.

Nat Immunol. 2015 Dec;16(12):1292. doi: 10.1038/ni1215-1292b. No abstract available.

PMID:
26580509
18.

Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.

Maltez VI, Tubbs AL, Cook KD, Aachoui Y, Falcone EL, Holland SM, Whitmire JK, Miao EA.

Immunity. 2015 Nov 17;43(5):987-97. doi: 10.1016/j.immuni.2015.10.010. Epub 2015 Nov 10.

19.

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

Finethy R, Jorgensen I, Haldar AK, de Zoete MR, Strowig T, Flavell RA, Yamamoto M, Nagarajan UM, Miao EA, Coers J.

Infect Immun. 2015 Dec;83(12):4740-9. doi: 10.1128/IAI.00856-15. Epub 2015 Sep 28.

20.

Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.

Aachoui Y, Kajiwara Y, Leaf IA, Mao D, Ting JP, Coers J, Aderem A, Buxbaum JD, Miao EA.

Cell Host Microbe. 2015 Sep 9;18(3):320-32. doi: 10.1016/j.chom.2015.07.016. Epub 2015 Aug 27.

21.

Pyroptotic cell death defends against intracellular pathogens.

Jorgensen I, Miao EA.

Immunol Rev. 2015 May;265(1):130-42. doi: 10.1111/imr.12287. Review.

22.

Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague.

Sivaraman V, Pechous RD, Stasulli NM, Eichelberger KR, Miao EA, Goldman WE.

PLoS Pathog. 2015 Mar 17;11(3):e1004688. doi: 10.1371/journal.ppat.1004688. eCollection 2015 Mar. Erratum in: PLoS Pathog. 2015 May;11(5):e1004921.

23.

Corrigendum: The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3.

Rayamajhi M, Miao EA.

Nat Immunol. 2015 Mar;16(3):326. doi: 10.1038/ni0315-326c. No abstract available.

PMID:
25689445
24.

NAIP inflammasomes give the NOD to bacterial ligands.

Maltez VI, Miao EA.

Trends Immunol. 2014 Nov;35(11):503-4. doi: 10.1016/j.it.2014.10.002. Epub 2014 Oct 18.

25.

The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3.

Rayamajhi M, Miao EA.

Nat Immunol. 2014 Dec;15(12):1100-2. doi: 10.1038/ni.3030. Erratum in: Nat Immunol. 2015 Mar;16(3):326. Nat Immunol. 2015 Dec;16(12):1292.

26.

WildCARDs: inflammatory caspases directly detect LPS.

Hagar JA, Aachoui Y, Miao EA.

Cell Res. 2015 Feb;25(2):149-50. doi: 10.1038/cr.2014.128. Epub 2014 Sep 30.

27.

NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.

West TE, Myers ND, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Miao EA, Hajjar AM, Peacock SJ, Liggitt HD, Skerrett SJ.

PLoS Negl Trop Dis. 2014 Sep 18;8(9):e3178. doi: 10.1371/journal.pntd.0003178. eCollection 2014 Sep.

28.

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

Pilla DM, Hagar JA, Haldar AK, Mason AK, Degrandi D, Pfeffer K, Ernst RK, Yamamoto M, Miao EA, Coers J.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6046-51. doi: 10.1073/pnas.1321700111. Epub 2014 Apr 8.

29.

Detection of cytosolic bacteria by inflammatory caspases.

Hagar JA, Miao EA.

Curr Opin Microbiol. 2014 Feb;17:61-6. doi: 10.1016/j.mib.2013.11.008. Epub 2013 Dec 22. Review.

30.

miniMAVS, You Complete Me!

Rayamajhi M, Miao EA, Moorman NJ.

Cell. 2014 Feb 13;156(4):629-30. doi: 10.1016/j.cell.2014.01.045.

31.

Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP.

Choi HW, Brooking-Dixon R, Neupane S, Lee CJ, Miao EA, Staats HF, Abraham SN.

Immunity. 2013 Dec 12;39(6):1108-20. doi: 10.1016/j.immuni.2013.11.009.

32.

Mechanisms of NOD-like receptor-associated inflammasome activation.

Wen H, Miao EA, Ting JP.

Immunity. 2013 Sep 19;39(3):432-41. doi: 10.1016/j.immuni.2013.08.037. Review.

33.

Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein.

Rayamajhi M, Zak DE, Chavarria-Smith J, Vance RE, Miao EA.

J Immunol. 2013 Oct 15;191(8):3986-9. doi: 10.4049/jimmunol.1301549. Epub 2013 Sep 16.

34.

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.

Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA.

Science. 2013 Sep 13;341(6151):1250-3. doi: 10.1126/science.1240988.

35.

Detection of pyroptosis by measuring released lactate dehydrogenase activity.

Rayamajhi M, Zhang Y, Miao EA.

Methods Mol Biol. 2013;1040:85-90. doi: 10.1007/978-1-62703-523-1_7.

36.

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection.

Aachoui Y, Sagulenko V, Miao EA, Stacey KJ.

Curr Opin Microbiol. 2013 Jun;16(3):319-26. doi: 10.1016/j.mib.2013.04.004. Epub 2013 May 23. Review.

37.

Caspase-11 protects against bacteria that escape the vacuole.

Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA.

Science. 2013 Feb 22;339(6122):975-8. doi: 10.1126/science.1230751. Epub 2013 Jan 24.

38.

YopM puts caspase-1 on ice.

Jørgensen I, Miao EA.

Cell Host Microbe. 2012 Dec 13;12(6):737-8. doi: 10.1016/j.chom.2012.11.006.

39.

Just say NO to NLRP3.

Rayamajhi M, Miao EA.

Nat Immunol. 2013 Jan;14(1):12-4. doi: 10.1038/ni.2493. No abstract available.

PMID:
23238751
40.

Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.

Inoue M, Williams KL, Oliver T, Vandenabeele P, Rajan JV, Miao EA, Shinohara ML.

Sci Signal. 2012 May 22;5(225):ra38. doi: 10.1126/scisignal.2002767.

41.

Caspase-1-induced pyroptotic cell death.

Miao EA, Rajan JV, Aderem A.

Immunol Rev. 2011 Sep;243(1):206-14. doi: 10.1111/j.1600-065X.2011.01044.x. Review.

42.

Salmonella and Caspase-1: A complex Interplay of Detection and Evasion.

Miao EA, Rajan JV.

Front Microbiol. 2011 Apr 25;2:85. doi: 10.3389/fmicb.2011.00085. eCollection 2011.

43.

Generation of a Listeria vaccine strain by enhanced caspase-1 activation.

Warren SE, Duong H, Mao DP, Armstrong A, Rajan J, Miao EA, Aderem A.

Eur J Immunol. 2011 Jul;41(7):1934-40. doi: 10.1002/eji.201041214. Epub 2011 Jun 8.

44.

The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection.

Rajan JV, Rodriguez D, Miao EA, Aderem A.

J Virol. 2011 May;85(9):4167-72. doi: 10.1128/JVI.01687-10. Epub 2011 Feb 2.

45.

Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.

Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, Dunipace EA, Warren SE, Miao EA, Vance RE.

Infect Immun. 2011 Apr;79(4):1606-14. doi: 10.1128/IAI.01187-10. Epub 2011 Jan 31.

46.

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

Miao EA, Leaf IA, Treuting PM, Mao DP, Dors M, Sarkar A, Warren SE, Wewers MD, Aderem A.

Nat Immunol. 2010 Dec;11(12):1136-42. doi: 10.1038/ni.1960. Epub 2010 Nov 7.

47.

Activation of the NLRP3 inflammasome by intracellular poly I:C.

Rajan JV, Warren SE, Miao EA, Aderem A.

FEBS Lett. 2010 Nov 19;584(22):4627-32. doi: 10.1016/j.febslet.2010.10.036. Epub 2010 Oct 23.

48.

Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2.

Warren SE, Armstrong A, Hamilton MK, Mao DP, Leaf IA, Miao EA, Aderem A.

J Immunol. 2010 Jul 15;185(2):818-21. doi: 10.4049/jimmunol.1000724. Epub 2010 Jun 18.

49.

Innate immune detection of bacterial virulence factors via the NLRC4 inflammasome.

Miao EA, Warren SE.

J Clin Immunol. 2010 Jul;30(4):502-6. doi: 10.1007/s10875-010-9386-5. Epub 2010 Mar 27.

50.

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome.

Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, Leaf IA, Aderem A.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3076-80. doi: 10.1073/pnas.0913087107. Epub 2010 Feb 1.

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