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Items: 46


Targeting innate immunity for tuberculosis vaccination.

Khader SA, Divangahi M, Hanekom W, Hill PC, Maeurer M, Makar KW, Mayer-Barber KD, Mhlanga MM, Nemes E, Schlesinger LS, van Crevel R, Vankalayapati R, Xavier RJ, Netea MG; Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group18.

J Clin Invest. 2019 Sep 3;129(9):3482-3491. doi: 10.1172/JCI128877. Review.


The lncRNA Connection Between Cellular Metabolism and Epigenetics in Trained Immunity.

Fok ET, Davignon L, Fanucchi S, Mhlanga MM.

Front Immunol. 2019 Jan 29;9:3184. doi: 10.3389/fimmu.2018.03184. eCollection 2018. Review.


Lnc-ing Trained Immunity to Chromatin Architecture.

Fanucchi S, Mhlanga MM.

Front Cell Dev Biol. 2019 Jan 24;7:2. doi: 10.3389/fcell.2019.00002. eCollection 2019. Review.


Transcriptionally induced enhancers in the macrophage immune response to Mycobacterium tuberculosis infection.

Denisenko E, Guler R, Mhlanga M, Suzuki H, Brombacher F, Schmeier S.

BMC Genomics. 2019 Jan 22;20(1):71. doi: 10.1186/s12864-019-5450-6.


Publisher Correction: Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments.

Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang EY, Stoychev S, Imakaev M, Grimm D, Wang KC, Li G, Sung WK, Mhlanga MM.

Nat Genet. 2019 Feb;51(2):364. doi: 10.1038/s41588-018-0341-3.


Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments.

Fanucchi S, Fok ET, Dalla E, Shibayama Y, Börner K, Chang EY, Stoychev S, Imakaev M, Grimm D, Wang KC, Li G, Sung WK, Mhlanga MM.

Nat Genet. 2019 Jan;51(1):138-150. doi: 10.1038/s41588-018-0298-2. Epub 2018 Dec 10. Erratum in: Nat Genet. 2019 Feb;51(2):364.


Candida auris in South Africa, 2012-2016.

Govender NP, Magobo RE, Mpembe R, Mhlanga M, Matlapeng P, Corcoran C, Govind C, Lowman W, Senekal M, Thomas J.

Emerg Infect Dis. 2018 Nov;24(11):2036-2040. doi: 10.3201/eid2411.180368.


Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA.

Barichievy S, Naidoo J, Boullé M, Scholefield J, Parihar SP, Coussens AK, Brombacher F, Sigal A, Mhlanga MM.

Front Cell Infect Microbiol. 2018 Aug 3;8:263. doi: 10.3389/fcimb.2018.00263. eCollection 2018.


Large Outbreaks of Fungal and Bacterial Bloodstream Infections in a Neonatal Unit, South Africa, 2012-2016.

van Schalkwyk E, Iyaloo S, Naicker SD, Maphanga TG, Mpembe RS, Zulu TG, Mhlanga M, Mahlangu S, Maloba MB, Ntlemo G, Sanyane K, Mawela D, Govender NP.

Emerg Infect Dis. 2018 Jul;24(7):1204-1212. doi: 10.3201/eid2407.171087.


Cryptococcal antigen positivity combined with the percentage of HIV-seropositive samples with CD4 counts <100 cells/μl identifies districts in South Africa with advanced burden of disease.

Coetzee LM, Cassim N, Sriruttan C, Mhlanga M, Govender NP, Glencross DK.

PLoS One. 2018 Jun 12;13(6):e0198993. doi: 10.1371/journal.pone.0198993. eCollection 2018.


Work-related musculoskeletal disorders among registered general nurses: a case of a large central hospital in Harare, Zimbabwe.

Chiwaridzo M, Makotore V, Dambi JM, Munambah N, Mhlanga M.

BMC Res Notes. 2018 May 18;11(1):315. doi: 10.1186/s13104-018-3412-8.


Three parallel information systems for malaria elimination in Swaziland, 2010-2015: are the numbers the same?

Zulu Z, Kunene S, Mkhonta N, Owiti P, Sikhondze W, Mhlanga M, Simelane Z, Geoffroy E, Zachariah R.

Public Health Action. 2018 Apr 25;8(Suppl 1):S13-S17. doi: 10.5588/pha.17.0058.


The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.


Genome-wide profiling of transcribed enhancers during macrophage activation.

Denisenko E, Guler R, Mhlanga MM, Suzuki H, Brombacher F, Schmeier S.

Epigenetics Chromatin. 2017 Oct 23;10(1):50. doi: 10.1186/s13072-017-0158-9.


Malaria Outbreak Investigation in Chipinge, Zimbabwe: A Case-control Study.

Kureya T, Ndaimani A, Mhlanga M.

Iran J Parasitol. 2017 Jul-Sep;12(3):423-432.


The emerging molecular biology toolbox for the study of long noncoding RNA biology.

Fok ET, Scholefield J, Fanucchi S, Mhlanga MM.

Epigenomics. 2017 Oct;9(10):1317-1327. doi: 10.2217/epi-2017-0062. Epub 2017 Sep 6. Review.


Lnc-ing inflammation to disease.

Magagula L, Gagliardi M, Naidoo J, Mhlanga M.

Biochem Soc Trans. 2017 Aug 15;45(4):953-62. doi: 10.1042/BST20160377. Epub 2017 Jul 7. Review.


Enhancer-Derived lncRNAs Regulate Genome Architecture: Fact or Fiction?

Fanucchi S, Mhlanga MM.

Trends Genet. 2017 Jun;33(6):375-377. doi: 10.1016/j.tig.2017.03.004. Epub 2017 Mar 27.


Emergency care capabilities in the Kingdom of Swaziland, Africa.

Chowa EP, Espinola JA, Sullivan AF, Mhlanga M, Camargo CA Jr.

Afr J Emerg Med. 2017 Mar;7(1):15-18. doi: 10.1016/j.afjem.2017.01.004. Epub 2017 Jan 28.


Stability and structural properties of gene regulation networks with coregulation rules.

Warrell J, Mhlanga M.

J Theor Biol. 2017 May 7;420:304-317. doi: 10.1016/j.jtbi.2016.10.020. Epub 2016 Nov 17.


Visualization of Enhancer-Derived Noncoding RNA.

Shibayama Y, Fanucchi S, Mhlanga MM.

Methods Mol Biol. 2017;1468:19-32. doi: 10.1007/978-1-4939-4035-6_3.


Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti.

Scholefield J, Henriques R, Savulescu AF, Fontan E, Boucharlat A, Laplantine E, Smahi A, Israël A, Agou F, Mhlanga MM.

Nat Commun. 2016 Sep 2;7:12629. doi: 10.1038/ncomms12629.


The epidemiology of malignant catarrhal fever (MCF) and contribution to cattle losses in farms around Rhodes Matopos National Park, Zimbabwe.

Mlilo D, Mhlanga M, Mwembe R, Sisito G, Moyo B, Sibanda B.

Trop Anim Health Prod. 2015 Jun;47(5):989-94. doi: 10.1007/s11250-015-0821-8. Epub 2015 Apr 12.


Non-coding RNAs and HIV: viral manipulation of host dark matter to shape the cellular environment.

Barichievy S, Naidoo J, Mhlanga MM.

Front Genet. 2015 Mar 26;6:108. doi: 10.3389/fgene.2015.00108. eCollection 2015. Review.


lncRNA and gene looping: what's the connection?

Shibayama Y, Fanucchi S, Magagula L, Mhlanga MM.

Transcription. 2014;5(3):e28658. doi: 10.4161/trns.28658. Review.


Nanoscopic Localization of Surface-Exposed Antigens of Borrelia burgdorferi.

Lemgruber L, Sant'Anna C, Griffths C, Abud Y, Mhlanga M, Wallich R, Frischknecht F.

Microsc Microanal. 2015 Jun;21(3):680-8. doi: 10.1017/S1431927615000318. Epub 2015 Mar 5.


Feasibility and validity of telephone triage for adverse events during a voluntary medical male circumcision campaign in Swaziland.

Ashengo TA, Grund J, Mhlanga M, Hlophe T, Mirira M, Bock N, Njeuhmeli E, Curran K, Mallas E, Fitzgerald L, Shoshore R, Moyo K, Bicego G.

BMC Public Health. 2014 Aug 18;14:858. doi: 10.1186/1471-2458-14-858.


Are genes switched on when they kiss?

Fanucchi S, Shibayama Y, Mhlanga MM.

Nucleus. 2014 Mar-Apr;5(2):103-12. doi: 10.4161/nucl.28352. Epub 2014 Feb 25. Review.


TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.

Tarantino N, Tinevez JY, Crowell EF, Boisson B, Henriques R, Mhlanga M, Agou F, Israël A, Laplantine E.

J Cell Biol. 2014 Jan 20;204(2):231-45. doi: 10.1083/jcb.201307172.


Chromosomal contact permits transcription between coregulated genes.

Fanucchi S, Shibayama Y, Burd S, Weinberg MS, Mhlanga MM.

Cell. 2013 Oct 24;155(3):606-20. doi: 10.1016/j.cell.2013.09.051. Epub 2013 Oct 24.


Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.

Parihar SP, Guler R, Khutlang R, Lang DM, Hurdayal R, Mhlanga MM, Suzuki H, Marais AD, Brombacher F.

J Infect Dis. 2014 Mar 1;209(5):754-63. doi: 10.1093/infdis/jit550. Epub 2013 Oct 16.


Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens.

Meliopoulos VA, Andersen LE, Birrer KF, Simpson KJ, Lowenthal JW, Bean AG, Stambas J, Stewart CR, Tompkins SM, van Beusechem VW, Fraser I, Mhlanga M, Barichievy S, Smith Q, Leake D, Karpilow J, Buck A, Jona G, Tripp RA.

FASEB J. 2012 Apr;26(4):1372-86. doi: 10.1096/fj.11-193466. Epub 2012 Jan 12. Review.


"Othering" the health worker: self-stigmatization of HIV/AIDS care among health workers in Swaziland.

de Vries DH, Galvin S, Mhlanga M, Cindzi B, Dlamini T.

J Int AIDS Soc. 2011 Dec 22;14:60. doi: 10.1186/1758-2652-14-60.


PALM and STORM: unlocking live-cell super-resolution.

Henriques R, Griffiths C, Hesper Rego E, Mhlanga MM.

Biopolymers. 2011 May;95(5):322-31. doi: 10.1002/bip.21586. Epub 2011 Jan 19. Review.


QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ.

Henriques R, Lelek M, Fornasiero EF, Valtorta F, Zimmer C, Mhlanga MM.

Nat Methods. 2010 May;7(5):339-40. doi: 10.1038/nmeth0510-339. No abstract available.


Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity.

Rolando M, Stefani C, Flatau G, Auberger P, Mettouchi A, Mhlanga M, Rapp U, Galmiche A, Lemichez E.

Cell Microbiol. 2010 Jul;12(7):891-905. doi: 10.1111/j.1462-5822.2010.01438.x. Epub 2010 May 20.


High-throughput SNP genotyping: combining tag SNPs and molecular beacons.

Barreiro LB, Henriques R, Mhlanga MM.

Methods Mol Biol. 2009;578:255-76. doi: 10.1007/978-1-60327-411-1_17.


In vivo colocalisation of oskar mRNA and trans-acting proteins revealed by quantitative imaging of the Drosophila oocyte.

Mhlanga MM, Bratu DP, Genovesio A, Rybarska A, Chenouard N, Nehrbass U, Olivo-Marin JC.

PLoS One. 2009 Jul 14;4(7):e6241. doi: 10.1371/journal.pone.0006241.


PALM and STORM: what hides beyond the Rayleigh limit?

Henriques R, Mhlanga MM.

Biotechnol J. 2009 Jun;4(6):846-57. doi: 10.1002/biot.200900024. Review.


Novel inner membrane retention signals in Pseudomonas aeruginosa lipoproteins.

Lewenza S, Mhlanga MM, Pugsley AP.

J Bacteriol. 2008 Sep;190(18):6119-25. doi: 10.1128/JB.00603-08. Epub 2008 Jul 18.


[Practising in the shadow of AIDS. Interview by Charles Meunier].

Gwagwa T, Mhlanga M.

Perspect Infirm. 2008 May-Jun;5(5):3-4. French. No abstract available.


Using tRNA-linked molecular beacons to image cytoplasmic mRNAs in live cells.

Mhlanga MM, Tyagi S.

Nat Protoc. 2006;1(3):1392-8.


tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells.

Mhlanga MM, Vargas DY, Fung CW, Kramer FR, Tyagi S.

Nucleic Acids Res. 2005 Apr 4;33(6):1902-12. Print 2005.


Visualizing the distribution and transport of mRNAs in living cells.

Bratu DP, Cha BJ, Mhlanga MM, Kramer FR, Tyagi S.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13308-13. Epub 2003 Oct 28.


Using molecular beacons to detect single-nucleotide polymorphisms with real-time PCR.

Mhlanga MM, Malmberg L.

Methods. 2001 Dec;25(4):463-71.


Spectral genotyping of human alleles.

Kostrikis LG, Tyagi S, Mhlanga MM, Ho DD, Kramer FR.

Science. 1998 Feb 20;279(5354):1228-9. No abstract available.


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