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Items: 1 to 50 of 156

1.

On predicting foldability of a protein from its sequence.

Mezei M.

Proteins. 2019 Sep 3. doi: 10.1002/prot.25811. [Epub ahead of print]

PMID:
31479556
2.

Transmitted Drug Resistance in Newly Diagnosed, Treatment-Naïve, HIV Type 1-Infected Patients in Hungary.

Áy É, Müller V, Mezei M, Pocskay Á, Koroknai A, Müller D, Győri Z, Marschalkó M, Tóth B, Kárpáti S, Lakatos B, Szlávik J, Takács M, Minárovits J.

J Glob Antimicrob Resist. 2019 Jul 19. pii: S2213-7165(19)30180-8. doi: 10.1016/j.jgar.2019.07.014. [Epub ahead of print]

PMID:
31330377
3.

Piloting a surveillance system for HIV drug resistance in the European Union.

van de Laar MJ, Bosman A, Pharris A, Andersson E, Assoumou L, Ay E, Bannert N, Bartmeyer B, Brady M, Chaix ML, Descamps D, Dauwe K, Fonager J, Hauser A, Lunar M, Mezei M, Neary M, Poljak M, van Sighem A, Verhofstede C, Amato-Gauci AJ, Broberg EK.

Euro Surveill. 2019 May;24(19). doi: 10.2807/1560-7917.ES.2019.24.19.1800390.

4.

Flavonol 7-O-Glucoside Herbacitrin Inhibits HIV-1 Replication through Simultaneous Integrase and Reverse Transcriptase Inhibition.

Áy É, Hunyadi A, Mezei M, Minárovits J, Hohmann J.

Evid Based Complement Alternat Med. 2019 Feb 3;2019:1064793. doi: 10.1155/2019/1064793. eCollection 2019.

5.

A Modifying Autoantigen in Graves' Disease.

Latif R, Mezei M, Morshed SA, Ma R, Ehrlich R, Davies TF.

Endocrinology. 2019 May 1;160(5):1008-1020. doi: 10.1210/en.2018-01048.

PMID:
30822352
6.

Virtual screening of a natural compound library at orthosteric and allosteric binding sites of the neurotensin receptor.

Rejwan Ali M, Sadoqi M, Boutajangout A, Mezei M.

J Biomol Struct Dyn. 2019 Oct;37(17):4494-4506. doi: 10.1080/07391102.2018.1552200. Epub 2019 Jan 9.

PMID:
30479178
7.

Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3.

Vincek AS, Patel J, Jaganathan A, Green A, Pierre-Louis V, Arora V, Rehmann J, Mezei M, Zhou MM, Ohlmeyer M, Mujtaba S.

Molecules. 2018 Aug 2;23(8). pii: E1930. doi: 10.3390/molecules23081930.

8.

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.

Adams D, Gonzalez-Duarte A, O'Riordan WD, Yang CC, Ueda M, Kristen AV, Tournev I, Schmidt HH, Coelho T, Berk JL, Lin KP, Vita G, Attarian S, Planté-Bordeneuve V, Mezei MM, Campistol JM, Buades J, Brannagan TH 3rd, Kim BJ, Oh J, Parman Y, Sekijima Y, Hawkins PN, Solomon SD, Polydefkis M, Dyck PJ, Gandhi PJ, Goyal S, Chen J, Strahs AL, Nochur SV, Sweetser MT, Garg PP, Vaishnaw AK, Gollob JA, Suhr OB.

N Engl J Med. 2018 Jul 5;379(1):11-21. doi: 10.1056/NEJMoa1716153.

9.

Concurrent inflammatory myopathy and myasthenia gravis with or without thymic pathology: A case series and literature review.

Huang K, Shojania K, Chapman K, Amiri N, Dehghan N, Mezei M.

Semin Arthritis Rheum. 2019 Feb;48(4):745-751. doi: 10.1016/j.semarthrit.2018.05.004. Epub 2018 Jun 28. Review.

PMID:
29958689
10.

Comparison of a quantum random number generator with pseudorandom number generators for their use in molecular Monte Carlo simulations.

Ghersi D, Parakh A, Mezei M.

J Comput Chem. 2017 Dec 5;38(31):2713-2720. doi: 10.1002/jcc.25065. Epub 2017 Sep 18.

PMID:
28925088
11.

Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies.

Ali MR, Sadoqi M, Møller SG, Boutajangout A, Mezei M.

J Mol Graph Model. 2017 Sep;76:36-42. doi: 10.1016/j.jmgm.2017.06.027. Epub 2017 Jun 29.

PMID:
28711758
12.

The BigLEN-GPR171 Peptide Receptor System Within the Basolateral Amygdala Regulates Anxiety-Like Behavior and Contextual Fear Conditioning.

Bobeck EN, Gomes I, Pena D, Cummings KA, Clem RL, Mezei M, Devi LA.

Neuropsychopharmacology. 2017 Dec;42(13):2527-2536. doi: 10.1038/npp.2017.79. Epub 2017 Apr 20.

13.

Rescore protein-protein docked ensembles with an interface contact statistics.

Mezei M.

Proteins. 2017 Feb;85(2):235-241. doi: 10.1002/prot.25209. Epub 2016 Dec 5.

PMID:
27862307
14.

TSH Receptor Signaling Abrogation by a Novel Small Molecule.

Latif R, Realubit RB, Karan C, Mezei M, Davies TF.

Front Endocrinol (Lausanne). 2016 Sep 27;7:130. eCollection 2016.

15.

Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7.

Ren C, Smith SG, Yap K, Li S, Li J, Mezei M, Rodriguez Y, Vincek A, Aguilo F, Walsh MJ, Zhou MM.

ACS Med Chem Lett. 2016 Feb 29;7(6):601-5. doi: 10.1021/acsmedchemlett.6b00042. eCollection 2016 Jun 9.

16.

Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.

Wardman JH, Gomes I, Bobeck EN, Stockert JA, Kapoor A, Bisignano P, Gupta A, Mezei M, Kumar S, Filizola M, Devi LA.

Sci Signal. 2016 May 31;9(430):ra55. doi: 10.1126/scisignal.aac8035.

17.

In Silico Modeling of Novel Drug Ligands for Treatment of Concussion Associated Tauopathy.

Zhao W, Ho L, Wang J, Bi W, Yemul S, Ward L, Freire D, Mazzola P, Brathwaite J, Mezei M, Sanchez R, Elder GA, Pasinetti GM.

J Cell Biochem. 2016 Oct;117(10):2241-8. doi: 10.1002/jcb.25521. Epub 2016 Jul 12.

18.

Identifying a Small Molecule Blocking Antigen Presentation in Autoimmune Thyroiditis.

Li CW, Menconi F, Osman R, Mezei M, Jacobson EM, Concepcion E, David CS, Kastrinsky DB, Ohlmeyer M, Tomer Y.

J Biol Chem. 2016 Feb 19;291(8):4079-90. doi: 10.1074/jbc.M115.694687. Epub 2015 Dec 24.

19.
20.

The role of protein "Stability patches" in molecular recognition: A case study of the human growth hormone-receptor complex.

Osman R, Mezei M, Engel S.

J Comput Chem. 2016 Apr 15;37(10):913-9. doi: 10.1002/jcc.24276. Epub 2015 Dec 21.

PMID:
26691434
21.

Characterization of the Binding Site of Aspartame in the Human Sweet Taste Receptor.

Maillet EL, Cui M, Jiang P, Mezei M, Hecht E, Quijada J, Margolskee RF, Osman R, Max M.

Chem Senses. 2015 Oct;40(8):577-86. doi: 10.1093/chemse/bjv045.

22.

Choline Acetyltransferase Mutations Causing Congenital Myasthenic Syndrome: Molecular Findings and Genotype-Phenotype Correlations.

Arredondo J, Lara M, Gospe SM Jr, Mazia CG, Vaccarezza M, Garcia-Erro M, Bowe CM, Chang CH, Mezei MM, Maselli RA.

Hum Mutat. 2015 Sep;36(9):881-93. doi: 10.1002/humu.22823. Epub 2015 Jul 24.

23.

Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer.

Kwon YJ, Petrie K, Leibovitch BA, Zeng L, Mezei M, Howell L, Gil V, Christova R, Bansal N, Yang S, Sharma R, Ariztia EV, Frankum J, Brough R, Sbirkov Y, Ashworth A, Lord CJ, Zelent A, Farias E, Zhou MM, Waxman S.

Mol Cancer Ther. 2015 Aug;14(8):1824-36. doi: 10.1158/1535-7163.MCT-14-0980-T. Epub 2015 Jun 15.

24.

A case of good syndrome presumed secondary to metastatic pancreatic thymoma in a patient presenting with a myasthenic crisis postthymectomy.

Jack KL, Kula M, Flint JD, Mezei MM.

J Clin Neuromuscul Dis. 2015 Mar;16(3):159-63. doi: 10.1097/CND.0000000000000070.

PMID:
25695921
25.

A genome-wide association study of myasthenia gravis.

Renton AE, Pliner HA, Provenzano C, Evoli A, Ricciardi R, Nalls MA, Marangi G, Abramzon Y, Arepalli S, Chong S, Hernandez DG, Johnson JO, Bartoccioni E, Scuderi F, Maestri M, Gibbs JR, Errichiello E, Chiò A, Restagno G, Sabatelli M, Macek M, Scholz SW, Corse A, Chaudhry V, Benatar M, Barohn RJ, McVey A, Pasnoor M, Dimachkie MM, Rowin J, Kissel J, Freimer M, Kaminski HJ, Sanders DB, Lipscomb B, Massey JM, Chopra M, Howard JF Jr, Koopman WJ, Nicolle MW, Pascuzzi RM, Pestronk A, Wulf C, Florence J, Blackmore D, Soloway A, Siddiqi Z, Muppidi S, Wolfe G, Richman D, Mezei MM, Jiwa T, Oger J, Drachman DB, Traynor BJ.

JAMA Neurol. 2015 Apr;72(4):396-404. doi: 10.1001/jamaneurol.2014.4103.

26.

Transmembrane domains of attraction on the TSH receptor.

Latif R, Ali MR, Mezei M, Davies TF.

Endocrinology. 2015 Feb;156(2):488-98. doi: 10.1210/en.2014-1509. Epub 2014 Nov 19.

27.

New small molecule agonists to the thyrotropin receptor.

Latif R, Ali MR, Ma R, David M, Morshed SA, Ohlmeyer M, Felsenfeld DP, Lau Z, Mezei M, Davies TF.

Thyroid. 2015 Jan;25(1):51-62. doi: 10.1089/thy.2014.0119.

28.

Computational approaches for modeling GPCR dimerization.

Meng XY, Mezei M, Cui M.

Curr Pharm Biotechnol. 2014;15(10):996-1006. Review.

29.

Monte Carlo loop refinement and virtual screening of the thyroid-stimulating hormone receptor transmembrane domain.

Ali MR, Latif R, Davies TF, Mezei M.

J Biomol Struct Dyn. 2015;33(5):1140-52. doi: 10.1080/07391102.2014.932310. Epub 2014 Jul 11.

30.

Mutations in B4GALNT1 (GM2 synthase) underlie a new disorder of ganglioside biosynthesis.

Harlalka GV, Lehman A, Chioza B, Baple EL, Maroofian R, Cross H, Sreekantan-Nair A, Priestman DA, Al-Turki S, McEntagart ME, Proukakis C, Royle L, Kozak RP, Bastaki L, Patton M, Wagner K, Coblentz R, Price J, Mezei M, Schlade-Bartusiak K, Platt FM, Hurles ME, Crosby AH.

Brain. 2013 Dec;136(Pt 12):3618-24. doi: 10.1093/brain/awt270. Epub 2013 Oct 7.

31.

Epigenetics of HIV infection: promising research areas and implications for therapy.

Ay E, Banati F, Mezei M, Bakos A, Niller HH, Buzás K, Minarovits J.

AIDS Rev. 2013 Jul-Sep;15(3):181-8. Review.

PMID:
24002202
32.

Increased Prevalence of Hypertension in Young Adults with High Heteroplasmy Levels of the MELAS m.3243A>G Mutation.

Hannah-Shmouni F, Sirrs S, Mezei MM, Waters PJ, Mattman A.

JIMD Rep. 2014;12:17-23. doi: 10.1007/8904_2013_239. Epub 2013 Jul 12.

33.

Safety of statin therapy in patients with mitochondrial diseases.

Hannah-Shmouni F, Al-Sarraf A, Frohlich J, Mezei MM, Sirrs S, Mattman A.

J Clin Lipidol. 2013 Mar-Apr;7(2):182. doi: 10.1016/j.jacl.2012.08.003. Epub 2012 Aug 10. No abstract available.

PMID:
23415441
34.

Performance of serum and dried blood spot acylcarnitine profiles for detection of fatty acid β-oxidation disorders in adult patients with rhabdomyolysis.

Al-Thihli K, Sinclair G, Sirrs S, Mezei M, Nelson J, Vallance H.

J Inherit Metab Dis. 2014 Mar;37(2):207-13. doi: 10.1007/s10545-012-9578-7. Epub 2013 Jan 8.

PMID:
23296367
35.

Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation.

Jin YJ, Cai CY, Mezei M, Ohlmeyer M, Sanchez R, Burakoff SJ.

AIDS Res Hum Retroviruses. 2013 Apr;29(4):725-31. doi: 10.1089/AID.2012.0286. Epub 2012 Dec 31.

36.

Cardiac screening investigations in adult-onset progressive external ophthalmoplegia patients.

Pfeffer G, Mezei MM.

Muscle Nerve. 2012 Oct;46(4):593-6. doi: 10.1002/mus.23538. Review.

PMID:
22987704
37.
38.

The ABCs of molecular dynamics simulations on B-DNA, circa 2012.

Beveridge DL, Cheatham TE 3rd, Mezei M.

J Biosci. 2012 Jul;37(3):379-97. Review.

39.

Levator palpebrae biopsy and diagnosis of progressive external ophthalmoplegia.

Pfeffer G, Waters PJ, Maguire J, Vallance HD, Wong VA, Mezei MM.

Can J Neurol Sci. 2012 Jul;39(4):520-4.

PMID:
22728862
40.

Predicting protein interactions by Brownian dynamics simulations.

Meng XY, Xu Y, Zhang HX, Mezei M, Cui M.

J Biomed Biotechnol. 2012;2012:121034. doi: 10.1155/2012/121034. Epub 2012 Feb 15.

41.

HIV‑1 molecular epidemiology in the Balkans: a melting pot for high genetic diversity.

Stanojevic M, Alexiev I, Beshkov D, Gökengin D, Mezei M, Minarovits J, Otelea D, Paraschiv S, Poljak M, Zidovec-Lepej S, Paraskevis D.

AIDS Rev. 2012 Jan-Mar;14(1):28-36. Review.

PMID:
22297502
42.

Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.

Naidu MD, Agarwal R, Pena LA, Cunha L, Mezei M, Shen M, Wilson DM 3rd, Liu Y, Sanchez Z, Chaudhary P, Wilson SH, Waring MJ.

PLoS One. 2011;6(9):e23679. doi: 10.1371/journal.pone.0023679. Epub 2011 Sep 15.

43.

Molecular docking: a powerful approach for structure-based drug discovery.

Meng XY, Zhang HX, Mezei M, Cui M.

Curr Comput Aided Drug Des. 2011 Jun;7(2):146-57. Review.

44.

Expanding the clinical phenotype of the mitochondrial m.13513G>A mutation with the first report of a fatal neonatal presentation.

Van Karnebeek CD, Waters PJ, Sargent MA, Mezei MM, Wong LJ, Wang J, Stöckler-Ipsiroglu S.

Dev Med Child Neurol. 2011 Jun;53(6):565-8. doi: 10.1111/j.1469-8749.2010.03907.x. Epub 2011 Apr 19. Erratum in: Dev Med Child Neurol. 2011 Aug;53(8):767. Mezey, Michelle M [corrected to Mezei, Michelle M].

45.

Molecular epidemiological analysis of env and pol sequences in newly diagnosed HIV type 1-infected, untreated patients in Hungary.

Mezei M, Ay E, Koroknai A, Tóth R, Balázs A, Bakos A, Gyori Z, Bánáti F, Marschalkó M, Kárpáti S, Minárovits J.

AIDS Res Hum Retroviruses. 2011 Nov;27(11):1243-7. doi: 10.1089/AID.2011.0077. Epub 2011 May 9.

PMID:
21453184
46.

Multisystem disorder in late-onset chronic progressive external ophthalmoplegia.

Pfeffer G, Sirrs S, Wade NK, Mezei MM.

Can J Neurol Sci. 2011 Jan;38(1):119-23.

PMID:
21156440
47.

Discriminatory power of stoichiometry-driven protein folding?

Mezei M.

J Biomol Struct Dyn. 2011 Feb;28(4):625-6; discussion 669-674. No abstract available.

PMID:
21142238
48.

Simulaid: a simulation facilitator and analysis program.

Mezei M.

J Comput Chem. 2010 Nov 15;31(14):2658-68. doi: 10.1002/jcc.21551.

PMID:
20740566
49.

Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.

Siatecka M, Sahr KE, Andersen SG, Mezei M, Bieker JJ, Peters LL.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15151-6. doi: 10.1073/pnas.1004996107. Epub 2010 Aug 9.

50.

Guillian-Barré syndrome in high tetraplegia following acute respiratory illness.

Grant C, Briscoe N, Mezei M, Krassioukov A.

Spinal Cord. 2011 Mar;49(3):480-1. doi: 10.1038/sc.2010.84. Epub 2010 Jul 6.

PMID:
20603630

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