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Items: 1 to 50 of 76

1.

Ribosomal Protein S6 Phosphorylation Is Involved in Novelty-Induced Locomotion, Synaptic Plasticity and mRNA Translation.

Puighermanal E, Biever A, Pascoli V, Melser S, Pratlong M, Cutando L, Rialle S, Severac D, Boubaker-Vitre J, Meyuhas O, Marsicano G, Lüscher C, Valjent E.

Front Mol Neurosci. 2017 Dec 21;10:419. doi: 10.3389/fnmol.2017.00419. eCollection 2017.

2.

Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-Cells.

Wittenberg AD, Azar S, Klochendler A, Stolovich-Rain M, Avraham S, Birnbaum L, Binder Gallimidi A, Katz M, Dor Y, Meyuhas O.

PLoS One. 2016 Feb 26;11(2):e0149995. doi: 10.1371/journal.pone.0149995. eCollection 2016. Erratum in: PLoS One. 2016;11(5):e0155281.

3.

Ribosomal Protein S6 Phosphorylation: Four Decades of Research.

Meyuhas O.

Int Rev Cell Mol Biol. 2015;320:41-73. doi: 10.1016/bs.ircmb.2015.07.006. Epub 2015 Aug 5. Review.

PMID:
26614871
4.

Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 Phosphorylation.

Salmond RJ, Brownlie RJ, Meyuhas O, Zamoyska R.

J Immunol. 2015 Nov 15;195(10):4615-22. doi: 10.4049/jimmunol.1501473. Epub 2015 Oct 9.

5.

Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney Growth.

Wu H, Chen J, Xu J, Dong Z, Meyuhas O, Chen JK.

J Am Soc Nephrol. 2016 Apr;27(4):1145-58. doi: 10.1681/ASN.2014121264. Epub 2015 Aug 21.

6.

Phosphorylation of Ribosomal Protein S6 Mediates Mammalian Target of Rapamycin Complex 1-Induced Parathyroid Cell Proliferation in Secondary Hyperparathyroidism.

Volovelsky O, Cohen G, Kenig A, Wasserman G, Dreazen A, Meyuhas O, Silver J, Naveh-Many T.

J Am Soc Nephrol. 2016 Apr;27(4):1091-101. doi: 10.1681/ASN.2015040339. Epub 2015 Aug 17.

7.

PKA-dependent phosphorylation of ribosomal protein S6 does not correlate with translation efficiency in striatonigral and striatopallidal medium-sized spiny neurons.

Biever A, Puighermanal E, Nishi A, David A, Panciatici C, Longueville S, Xirodimas D, Gangarossa G, Meyuhas O, Hervé D, Girault JA, Valjent E.

J Neurosci. 2015 Mar 11;35(10):4113-30. doi: 10.1523/JNEUROSCI.3288-14.2015.

8.

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.

Faller WJ, Jackson TJ, Knight JR, Ridgway RA, Jamieson T, Karim SA, Jones C, Radulescu S, Huels DJ, Myant KB, Dudek KM, Casey HA, Scopelliti A, Cordero JB, Vidal M, Pende M, Ryazanov AG, Sonenberg N, Meyuhas O, Hall MN, Bushell M, Willis AE, Sansom OJ.

Nature. 2015 Jan 22;517(7535):497-500. doi: 10.1038/nature13896. Epub 2014 Nov 5.

9.

Reassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs.

Patursky-Polischuk I, Kasir J, Miloslavski R, Hayouka Z, Hausner-Hanochi M, Stolovich-Rain M, Tsukerman P, Biton M, Mudhasani R, Jones SN, Meyuhas O.

PLoS One. 2014 Oct 22;9(10):e109410. doi: 10.1371/journal.pone.0109410. eCollection 2014.

10.

The race to decipher the top secrets of TOP mRNAs.

Meyuhas O, Kahan T.

Biochim Biophys Acta. 2015 Jul;1849(7):801-11. doi: 10.1016/j.bbagrm.2014.08.015. Epub 2014 Sep 16. Review.

PMID:
25234618
11.

Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy.

Xu J, Chen J, Dong Z, Meyuhas O, Chen JK.

Kidney Int. 2015 Mar;87(3):543-56. doi: 10.1038/ki.2014.302. Epub 2014 Sep 17.

12.

Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.

Miloslavski R, Cohen E, Avraham A, Iluz Y, Hayouka Z, Kasir J, Mudhasani R, Jones SN, Cybulski N, Rüegg MA, Larsson O, Gandin V, Rajakumar A, Topisirovic I, Meyuhas O.

J Mol Cell Biol. 2014 Jun;6(3):255-66. doi: 10.1093/jmcb/mju008. Epub 2014 Mar 13.

13.

Parallel measurement of dynamic changes in translation rates in single cells.

Han K, Jaimovich A, Dey G, Ruggero D, Meyuhas O, Sonenberg N, Meyer T.

Nat Methods. 2014 Jan;11(1):86-93. doi: 10.1038/nmeth.2729. Epub 2013 Nov 10.

14.

Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.

Khalaileh A, Dreazen A, Khatib A, Apel R, Swisa A, Kidess-Bassir N, Maitra A, Meyuhas O, Dor Y, Zamir G.

Cancer Res. 2013 Mar 15;73(6):1811-20. doi: 10.1158/0008-5472.CAN-12-2014. Epub 2013 Jan 29.

15.

Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program.

Chauvin C, Koka V, Nouschi A, Mieulet V, Hoareau-Aveilla C, Dreazen A, Cagnard N, Carpentier W, Kiss T, Meyuhas O, Pende M.

Oncogene. 2014 Jan 23;33(4):474-83. doi: 10.1038/onc.2012.606. Epub 2013 Jan 14.

PMID:
23318442
16.

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E.

Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, Meyuhas O, Shokat KM, Ruggero D.

Cancer Cell. 2010 Mar 16;17(3):249-61. doi: 10.1016/j.ccr.2010.01.021.

17.

LKB1 regulates pancreatic beta cell size, polarity, and function.

Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ Jr, Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N, Dor Y.

Cell Metab. 2009 Oct;10(4):296-308. doi: 10.1016/j.cmet.2009.08.010.

18.

Mice deficient in ribosomal protein S6 phosphorylation suffer from muscle weakness that reflects a growth defect and energy deficit.

Ruvinsky I, Katz M, Dreazen A, Gielchinsky Y, Saada A, Freedman N, Mishani E, Zimmerman G, Kasir J, Meyuhas O.

PLoS One. 2009 May 19;4(5):e5618. doi: 10.1371/journal.pone.0005618.

19.

Ribosomal protein S6 kinase from TOP mRNAs to cell size.

Meyuhas O, Dreazen A.

Prog Mol Biol Transl Sci. 2009;90:109-53. doi: 10.1016/S1877-1173(09)90003-5. Epub 2009 Oct 27. Review.

PMID:
20374740
20.

The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner.

Patursky-Polischuk I, Stolovich-Rain M, Hausner-Hanochi M, Kasir J, Cybulski N, Avruch J, Rüegg MA, Hall MN, Meyuhas O.

Mol Cell Biol. 2009 Feb;29(3):640-9. doi: 10.1128/MCB.00980-08. Epub 2008 Dec 1. Erratum in: Mol Cell Biol. 2009 Mar;29(6):1670.

21.

Physiological roles of ribosomal protein S6: one of its kind.

Meyuhas O.

Int Rev Cell Mol Biol. 2008;268:1-37. doi: 10.1016/S1937-6448(08)00801-0. Review.

PMID:
18703402
22.

The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes.

Markert A, Grimm M, Martinez J, Wiesner J, Meyerhans A, Meyuhas O, Sickmann A, Fischer U.

EMBO Rep. 2008 Jun;9(6):569-75. doi: 10.1038/embor.2008.72. Epub 2008 May 16.

23.

Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling.

Jeon YJ, Kim IK, Hong SH, Nan H, Kim HJ, Lee HJ, Masuda ES, Meyuhas O, Oh BH, Jung YK.

Oncogene. 2008 Jul 17;27(31):4344-52. doi: 10.1038/onc.2008.73. Epub 2008 Mar 24.

PMID:
18362888
24.

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

Ruvinsky I, Meyuhas O.

Trends Biochem Sci. 2006 Jun;31(6):342-8. Epub 2006 May 6. Review.

PMID:
16679021
25.

Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.

Ruvinsky I, Sharon N, Lerer T, Cohen H, Stolovich-Rain M, Nir T, Dor Y, Zisman P, Meyuhas O.

Genes Dev. 2005 Sep 15;19(18):2199-211.

26.

Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation.

Karni R, Gus Y, Dor Y, Meyuhas O, Levitzki A.

Mol Cell Biol. 2005 Jun;25(12):5031-9.

27.
28.

Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs.

Hornstein E, Tang H, Meyuhas O.

Cold Spring Harb Symp Quant Biol. 2001;66:477-84. Review. No abstract available.

PMID:
12762050
30.

Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia.

Karni R, Dor Y, Keshet E, Meyuhas O, Levitzki A.

J Biol Chem. 2002 Nov 8;277(45):42919-25. Epub 2002 Aug 27.

31.

S6 phosphorylation-independent pathways regulate translation of 5'-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells.

Barth-Baus D, Stratton CA, Parrott L, Myerson H, Meyuhas O, Templeton DJ, Landreth GE, Hensold JO.

Nucleic Acids Res. 2002 May 1;30(9):1919-28.

32.
33.

Interplay in lipoplexes between type of pDNA promoter and lipid composition determines transfection efficiency of human growth hormone in NIH3T3 cells in culture.

Kerner M, Meyuhas O, Hirsch-Lerner D, Rosen LJ, Min Z, Barenholz Y.

Biochim Biophys Acta. 2001 May 31;1532(1-2):128-36.

PMID:
11420182
34.

Synthesis of the translational apparatus is regulated at the translational level.

Meyuhas O.

Eur J Biochem. 2000 Nov;267(21):6321-30. Review.

35.

Overexpression of poly(A)-binding protein down-regulates the translation or the abundance of its own mRNA.

Hornstein E, Harel H, Levy G, Meyuhas O.

FEBS Lett. 1999 Aug 27;457(2):209-13.

36.
37.
38.

Growth-dependent and PKC-mediated translational regulation of the upstream stimulating factor-2 (USF2) mRNA in hematopoietic cells.

Zhang ZC, Nechushtan H, Jacob-Hirsch J, Avni D, Meyuhas O, Razin E.

Oncogene. 1998 Feb 12;16(6):763-9.

40.
42.
45.

Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control.

Levy S, Avni D, Hariharan N, Perry RP, Meyuhas O.

Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3319-23.

46.

The mammalian genome contains a high proportion of processed pseudogenes corresponding to ribosomal protein L19.

Shiran A, Flusser G, Aloni R, Meyuhas O.

Biochem Int. 1990 Dec;22(5):921-8.

PMID:
2099152
47.
48.
49.

Translational control of ribosomal protein production in mammalian cells.

Perry RP, Meyuhas O.

Enzyme. 1990;44(1-4):83-92. Review.

PMID:
2133661
50.

Glucocorticoids induce transcription of ribosomal protein genes in rat liver.

Flusser G, Ginzburg V, Meyuhas O.

Mol Cell Endocrinol. 1989 Jul;64(2):213-22.

PMID:
2792563

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