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Items: 32

1.

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens.

Pan J, Meyers RM, Michel BC, Mashtalir N, Sizemore AE, Wells JN, Cassel SH, Vazquez F, Weir BA, Hahn WC, Marsh JA, Tsherniak A, Kadoch C.

Cell Syst. 2018 May 23;6(5):555-568.e7. doi: 10.1016/j.cels.2018.04.011. Epub 2018 May 16.

2.

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.

Chen L, Alexe G, Dharia NV, Ross L, Iniguez AB, Conway AS, Wang EJ, Veschi V, Lam N, Qi J, Gustafson WC, Nasholm N, Vazquez F, Weir BA, Cowley GS, Ali LD, Pantel S, Jiang G, Harrington WF, Lee Y, Goodale A, Lubonja R, Krill-Burger JM, Meyers RM, Tsherniak A, Root DE, Bradner JE, Golub TR, Roberts CW, Hahn WC, Weiss WA, Thiele CJ, Stegmaier K.

J Clin Invest. 2018 Jan 2;128(1):446-462. doi: 10.1172/JCI90793. Epub 2017 Dec 4.

3.

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

Meyers RM, Bryan JG, McFarland JM, Weir BA, Sizemore AE, Xu H, Dharia NV, Montgomery PG, Cowley GS, Pantel S, Goodale A, Lee Y, Ali LD, Jiang G, Lubonja R, Harrington WF, Strickland M, Wu T, Hawes DC, Zhivich VA, Wyatt MR, Kalani Z, Chang JJ, Okamoto M, Stegmaier K, Golub TR, Boehm JS, Vazquez F, Root DE, Hahn WC, Tsherniak A.

Nat Genet. 2017 Dec;49(12):1779-1784. doi: 10.1038/ng.3984. Epub 2017 Oct 30.

4.

Defining a Cancer Dependency Map.

Tsherniak A, Vazquez F, Montgomery PG, Weir BA, Kryukov G, Cowley GS, Gill S, Harrington WF, Pantel S, Krill-Burger JM, Meyers RM, Ali L, Goodale A, Lee Y, Jiang G, Hsiao J, Gerath WFJ, Howell S, Merkel E, Ghandi M, Garraway LA, Root DE, Golub TR, Boehm JS, Hahn WC.

Cell. 2017 Jul 27;170(3):564-576.e16. doi: 10.1016/j.cell.2017.06.010.

5.

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies.

Hwang JK, Wang C, Du Z, Meyers RM, Kepler TB, Neuberg D, Kwong PD, Mascola JR, Joyce MG, Bonsignori M, Haynes BF, Yeap LS, Alt FW.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8614-8619. doi: 10.1073/pnas.1709203114. Epub 2017 Jul 26.

6.

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting.

Aguirre AJ, Meyers RM, Weir BA, Vazquez F, Zhang CZ, Ben-David U, Cook A, Ha G, Harrington WF, Doshi MB, Kost-Alimova M, Gill S, Xu H, Ali LD, Jiang G, Pantel S, Lee Y, Goodale A, Cherniack AD, Oh C, Kryukov G, Cowley GS, Garraway LA, Stegmaier K, Roberts CW, Golub TR, Meyerson M, Root DE, Tsherniak A, Hahn WC.

Cancer Discov. 2016 Aug;6(8):914-29. doi: 10.1158/2159-8290.CD-16-0154. Epub 2016 Jun 3.

7.

Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing.

Hu J, Meyers RM, Dong J, Panchakshari RA, Alt FW, Frock RL.

Nat Protoc. 2016 May;11(5):853-71. doi: 10.1038/nprot.2016.043. Epub 2016 Mar 31.

8.

Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.

Schwer B, Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2258-63. doi: 10.1073/pnas.1525564113. Epub 2016 Feb 12.

9.

Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.

Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW, Schwer B.

Cell. 2016 Feb 11;164(4):644-55. doi: 10.1016/j.cell.2015.12.039.

10.

Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.

Hu J, Zhang Y, Zhao L, Frock RL, Du Z, Meyers RM, Meng FL, Schatz DG, Alt FW.

Cell. 2015 Nov 5;163(4):947-59. doi: 10.1016/j.cell.2015.10.016. Epub 2015 Oct 22.

11.

Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes.

Yeap LS, Hwang JK, Du Z, Meyers RM, Meng FL, JakubauskaitÄ— A, Liu M, Mani V, Neuberg D, Kepler TB, Wang JH, Alt FW.

Cell. 2015 Nov 19;163(5):1124-1137. doi: 10.1016/j.cell.2015.10.042. Epub 2015 Nov 12.

12.

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW.

Nature. 2015 Sep 3;525(7567):134-139. doi: 10.1038/nature14970. Epub 2015 Aug 26.

13.

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

Frock RL, Hu J, Meyers RM, Ho YJ, Kii E, Alt FW.

Nat Biotechnol. 2015 Feb;33(2):179-86. doi: 10.1038/nbt.3101. Epub 2014 Dec 15.

14.

Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability.

Meng FL, Du Z, Federation A, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig MC, Bradner JE, Liu XS, Alt FW.

Cell. 2014 Dec 18;159(7):1538-48. doi: 10.1016/j.cell.2014.11.014. Epub 2014 Dec 4.

15.

Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.

Hu J, Tepsuporn S, Meyers RM, Gostissa M, Alt FW.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10269-74. doi: 10.1073/pnas.1410112111. Epub 2014 Jun 30.

16.

IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.

Gostissa M, Schwer B, Chang A, Dong J, Meyers RM, Marecki GT, Choi VW, Chiarle R, Zarrin AA, Alt FW.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2644-9. doi: 10.1073/pnas.1324176111. Epub 2014 Feb 3.

17.

Microbial colonization influences early B-lineage development in the gut lamina propria.

Wesemann DR, Portuguese AJ, Meyers RM, Gallagher MP, Cluff-Jones K, Magee JM, Panchakshari RA, Rodig SJ, Kepler TB, Alt FW.

Nature. 2013 Sep 5;501(7465):112-5. doi: 10.1038/nature12496. Epub 2013 Aug 21.

18.

Diabetes management in long-term care facilities: a practical guide.

Meyers RM, Reger L.

J Am Med Dir Assoc. 2009 Oct;10(8):589. doi: 10.1016/j.jamda.2009.07.007. Epub 2009 Sep 3. No abstract available.

PMID:
19808159
19.

Safety and efficacy of home intravenous therapy.

Brooks B, Meyers RM.

J Am Geriatr Soc. 2008 Jan;56(1):177. doi: 10.1111/j.1532-5415.2007.01487.x. No abstract available.

PMID:
18184216
20.

Variability in glycosylated hemoglobin values in diabetic patients living in long-term care facilities.

Meyers RM, Broton JC, Woo-Rippe KW, Lindquist SA, Cen YY.

J Am Med Dir Assoc. 2007 Oct;8(8):511-4. Epub 2007 Sep 17.

PMID:
17931574
21.
22.

The Ojibwa Health Study: fish residue comparisons for Lakes Superior, Michigan, and Huron.

Dellinger JA, Meyers RM, Gebhardt KJ, Hansen LK.

Toxicol Ind Health. 1996 May-Aug;12(3-4):393-402.

PMID:
8843556
23.

Decisionmaking regarding the initiation of tube feedings in the severely demented elderly: a review.

Meyers RM, Grodin MA.

J Am Geriatr Soc. 1991 May;39(5):526-31. Review. No abstract available.

PMID:
1902494
24.

Incidence of perforation with Goode T-tube.

Matt BH, Miller RP, Meyers RM, Campbell JM, Cotton RT.

Int J Pediatr Otorhinolaryngol. 1991 Feb;21(1):1-6.

PMID:
2037413
25.

Do-not-resuscitate orders in an extended-care study group.

Meyers RM, Lurie N, Breitenbucher RB, Waring CJ.

J Am Geriatr Soc. 1990 Sep;38(9):1011-5.

PMID:
2212435
26.

Interaction of AD2+D2 protein and simian virus 40 large T antigen with the large tumor antigen binding site I.

Fisher EF, Feist PL, Beaucage SL, Meyers RM, Tjian R, Caruthers MH.

Biochemistry. 1984 Dec 4;23(25):5938-44.

PMID:
6098305
27.

Carcinoma of the buccal mucosa and retromolar area.

Skolnik EM, Campbell JM, Meyers RM.

Otolaryngol Clin North Am. 1972 Jun;5(2):327-31. No abstract available.

PMID:
5039662
28.

Dermoid cysts of the nose.

Skolnik EM, Campbell JM, Meyers RM.

Laryngoscope. 1971 Oct;81(10):1632-7. No abstract available.

PMID:
4255918
29.

Malignancies of the parotid gland.

Skolnik EM, Meyers RM, Tardy ME Jr, Ross JC, Saberman MN.

Arch Otolaryngol. 1971 Mar;93(3):256-60. No abstract available.

PMID:
5100627
30.

Ototoxic effects of gentamicin.

Meyers RM.

Arch Otolaryngol. 1970 Aug;92(2):160-2. No abstract available.

PMID:
5310642
31.

Superiorly based pharyngeal flap.

Skolnik EM, Saberman MN, Meyers RM, Ross JC.

Laryngoscope. 1969 Aug;79(8):1396-9. No abstract available.

PMID:
5806986
32.

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