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Items: 1 to 50 of 177

1.

Radiomic Biomarkers Informative of Cancerous Transformation in Neurofibromatosis-1 Plexiform Tumors.

Uthoff J, Stefano FA, Panzer K, Darbro BW, Sato TS, Khanna R, Quelle DE, Meyerholz DK, Weimer J, Sieren JC.

J Neuroradiol. 2018 Jun 26. pii: S0150-9861(17)30519-9. doi: 10.1016/j.neurad.2018.05.006. [Epub ahead of print]

PMID:
29958847
2.

A porcine model of neurofibromatosis type 1 that mimics the human disease.

White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM.

JCI Insight. 2018 Jun 21;3(12). pii: 120402. doi: 10.1172/jci.insight.120402. [Epub ahead of print]

3.

Citation Index Is Not Critically Important to Veterinary Pathology, Medicine, and Research.

Ward JM, Meyerholz DK.

Vet Pathol. 2018 Jul;55(4):595-596. doi: 10.1177/0300985818758472. No abstract available.

PMID:
29890927
4.

Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia.

Hua X, Vijay R, Channappanavar R, Athmer J, Meyerholz DK, Pagedar N, Tilley S, Perlman S.

JCI Insight. 2018 Jun 7;3(11). pii: 99025. doi: 10.1172/jci.insight.99025. [Epub ahead of print]

5.

Principles and approaches for reproducible scoring of tissue stains in research.

Meyerholz DK, Beck AP.

Lab Invest. 2018 May 30. doi: 10.1038/s41374-018-0057-0. [Epub ahead of print] Review.

PMID:
29849125
6.

The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity.

Reznikov LR, Meyerholz DK, Abou Alaiwa MH, Kuan SP, Liao YJ, Bormann NL, Bair TB, Price M, Stoltz DA, Welsh MJ.

Am J Physiol Lung Cell Mol Physiol. 2018 Apr 5. doi: 10.1152/ajplung.00557.2017. [Epub ahead of print]

7.

MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity.

Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, Nicholls JM, Meyerholz DK, Kuranga SA, Mamo G, Zhou Z, So RTY, Hemida MG, Webby RJ, Roger F, Rambaut A, Poon LLM, Perlman S, Drosten C, Chevalier V, Peiris M.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3144-3149. doi: 10.1073/pnas.1718769115. Epub 2018 Mar 5.

8.

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs.

Meyerholz DK, Stoltz DA, Gansemer ND, Ernst SE, Cook DP, Strub MD, LeClair EN, Barker CK, Adam RJ, Leidinger MR, Gibson-Corley KN, Karp PH, Welsh MJ, McCray PB Jr.

Lab Invest. 2018 Jun;98(6):825-838. doi: 10.1038/s41374-018-0026-7. Epub 2018 Feb 21.

PMID:
29467455
9.

Solitary Cholinergic Stimulation Induces Airway Hyperreactivity and Transcription of Distinct Pro-inflammatory Pathways.

Reznikov LR, Meyerholz DK, Kuan SP, Guevara MV, Atanasova KR, Abou Alaiwa MH.

Lung. 2018 Apr;196(2):219-229. doi: 10.1007/s00408-018-0091-0. Epub 2018 Jan 29.

PMID:
29380034
10.

Microglia are required for protection against lethal coronavirus encephalitis in mice.

Wheeler DL, Sariol A, Meyerholz DK, Perlman S.

J Clin Invest. 2018 Mar 1;128(3):931-943. doi: 10.1172/JCI97229. Epub 2018 Jan 29.

11.

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.

Schmidt ME, Knudson CJ, Hartwig SM, Pewe LL, Meyerholz DK, Langlois RA, Harty JT, Varga SM.

PLoS Pathog. 2018 Jan 2;14(1):e1006810. doi: 10.1371/journal.ppat.1006810. eCollection 2018 Jan.

12.

Pathology and Pathogenesis of Immune-Mediated Diseases of Animals.

Diehl L, Meyerholz DK, Day MJ, Affolter VK.

Vet Pathol. 2018 Jan;55(1):5-7. doi: 10.1177/0300985817739091. No abstract available.

PMID:
29254471
13.

Depletion of Airway Submucosal Glands and TP63+KRT5+ Basal Cells in Obliterative Bronchiolitis.

Swatek AM, Lynch TJ, Crooke AK, Anderson PJ, Tyler SR, Brooks L, Ivanovic M, Klesney-Tait JA, Eberlein M, Pena T, Meyerholz DK, Engelhardt JF, Parekh KR.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1045-1057. doi: 10.1164/rccm.201707-1368OC.

PMID:
29236513
14.

Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development.

Chakravarti B, Yang J, Ahlers-Dannen KE, Luo Z, Flaherty HA, Meyerholz DK, Anderson ME, Fisher RA.

J Am Heart Assoc. 2017 Oct 27;6(11). pii: e007038. doi: 10.1161/JAHA.117.007038.

15.

5'-methylschweinfurthin G reduces chondrosarcoma tumor growth .

Stevens JW, Meyerholz DK, Neighbors JD, Morcuende JA.

J Orthop Res. 2018 Apr;36(4):1283-1293. doi: 10.1002/jor.23753. Epub 2017 Nov 21.

PMID:
28960476
16.

Maintenance of Distal Intestinal Structure in the Face of Prolonged Fasting: A Comparative Examination of Species From Five Vertebrate Classes.

McCue MD, Passement CA, Meyerholz DK.

Anat Rec (Hoboken). 2017 Dec;300(12):2208-2219. doi: 10.1002/ar.23691. Epub 2017 Oct 5.

PMID:
28941363
17.

CF airway smooth muscle transcriptome reveals a role for PYK2.

Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA.

JCI Insight. 2017 Sep 7;2(17). pii: 95332. doi: 10.1172/jci.insight.95332. [Epub ahead of print]

18.

Patterns of host gene expression associated with harboring a foregut microbial community.

Kohl KD, Oakeson KF, Dunn D, Meyerholz DK, Dale C, Weiss RB, Dearing MD.

BMC Genomics. 2017 Sep 6;18(1):697. doi: 10.1186/s12864-017-4101-z.

19.

Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models.

Meyerholz DK, Ofori-Amanfo GK, Leidinger MR, Goeken JA, Khanna R, Sieren JC, Darbro BW, Quelle DE, Weimer JM.

J Histochem Cytochem. 2017 Oct;65(10):607-618. doi: 10.1369/0022155417729357. Epub 2017 Aug 28.

PMID:
28846462
20.

Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus.

Wheeler DL, Athmer J, Meyerholz DK, Perlman S.

J Virol. 2017 Aug 23. pii: JVI.01099-17. doi: 10.1128/JVI.01099-17. [Epub ahead of print]

21.

Approaches to Evaluate Lung Inflammation in Translational Research.

Meyerholz DK, Sieren JC, Beck AP, Flaherty HA.

Vet Pathol. 2018 Jan;55(1):42-52. doi: 10.1177/0300985817726117. Epub 2017 Aug 16. Review.

PMID:
28812529
22.

Genetic ataxia telangiectasia porcine model phenocopies the multisystemic features of the human disease.

Beraldi R, Meyerholz DK, Savinov A, Kovács AD, Weimer JM, Dykstra JA, Geraets RD, Pearce DA.

Biochim Biophys Acta. 2017 Nov;1863(11):2862-2870. doi: 10.1016/j.bbadis.2017.07.020. Epub 2017 Jul 23.

PMID:
28746835
23.

Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.

Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):E5444-E5453. doi: 10.1073/pnas.1704099114. Epub 2017 Jun 19.

24.

The Evolving Significance and Future Relevance of the Impact Factor.

Meyerholz DK, Flaherty HA.

Vet Pathol. 2017 Jul;54(4):721-722. doi: 10.1177/0300985817690209. No abstract available.

PMID:
28622493
25.

Postnatal airway growth in cystic fibrosis piglets.

Adam RJ, Abou Alaiwa MH, Bouzek DC, Cook DP, Gansemer ND, Taft PJ, Powers LS, Stroik MR, Hoegger MJ, McMenimen JD, Hoffman EA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA.

J Appl Physiol (1985). 2017 Sep 1;123(3):526-533. doi: 10.1152/japplphysiol.00263.2017. Epub 2017 Jun 15.

PMID:
28620056
26.

Gel-forming mucins form distinct morphologic structures in airways.

Ostedgaard LS, Moninger TO, McMenimen JD, Sawin NM, Parker CP, Thornell IM, Powers LS, Gansemer ND, Bouzek DC, Cook DP, Meyerholz DK, Abou Alaiwa MH, Stoltz DA, Welsh MJ.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6842-6847. doi: 10.1073/pnas.1703228114. Epub 2017 Jun 12.

27.

Simple and reproducible approaches for the collection of select porcine ganglia.

Meyerholz DK, Reznikov LR.

J Neurosci Methods. 2017 Sep 1;289:93-98. doi: 10.1016/j.jneumeth.2017.06.005. Epub 2017 Jun 8.

PMID:
28602889
28.

CD8 T cells contribute to lacrimal gland pathology in the nonobese diabetic mouse model of Sjögren syndrome.

Barr JY, Wang X, Meyerholz DK, Lieberman SM.

Immunol Cell Biol. 2017 Sep;95(8):684-694. doi: 10.1038/icb.2017.38. Epub 2017 May 3.

29.

Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection.

Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S.

J Immunol. 2017 May 15;198(10):4046-4053. doi: 10.4049/jimmunol.1601896. Epub 2017 Apr 3.

30.

Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice.

Li K, Wohlford-Lenane CL, Channappanavar R, Park JE, Earnest JT, Bair TB, Bates AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB Jr.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3119-E3128. doi: 10.1073/pnas.1619109114. Epub 2017 Mar 27.

31.

Mounier-Kuhn syndrome: a case of tracheal smooth muscle remodeling.

Cook DP, Adam RJ, Abou Alaiwa MH, Eberlein M, Klesney-Tait JA, Parekh KR, Meyerholz DK, Stoltz DA.

Clin Case Rep. 2016 Dec 29;5(2):93-96. doi: 10.1002/ccr3.794. eCollection 2017 Feb.

32.

Abnormal CD161+ immune cells and retinoic acid receptor-related orphan receptor γt-mediate enhanced IL-17F expression in the setting of genetic hypertension.

Singh MV, Cicha MZ, Kumar S, Meyerholz DK, Irani K, Chapleau MW, Abboud FM.

J Allergy Clin Immunol. 2017 Sep;140(3):809-821.e3. doi: 10.1016/j.jaci.2016.11.039. Epub 2017 Jan 16.

PMID:
28093217
33.

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection.

Fehr AR, Channappanavar R, Jankevicius G, Fett C, Zhao J, Athmer J, Meyerholz DK, Ahel I, Perlman S.

MBio. 2016 Dec 13;7(6). pii: e01721-16. doi: 10.1128/mBio.01721-16.

34.

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice.

Reznikov LR, Meyerholz DK, Adam RJ, Abou Alaiwa M, Jaffer O, Michalski AS, Powers LS, Price MP, Stoltz DA, Welsh MJ.

PLoS One. 2016 Nov 7;11(11):e0166089. doi: 10.1371/journal.pone.0166089. eCollection 2016.

35.

Nicotine Mediates CD161a+ Renal Macrophage Infiltration and Premature Hypertension in the Spontaneously Hypertensive Rat.

Harwani SC, Ratcliff J, Sutterwala FS, Ballas ZK, Meyerholz DK, Chapleau MW, Abboud FM.

Circ Res. 2016 Oct 28;119(10):1101-1115. Epub 2016 Sep 22.

36.

The Spl Serine Proteases Modulate Staphylococcus aureus Protein Production and Virulence in a Rabbit Model of Pneumonia.

Paharik AE, Salgado-Pabon W, Meyerholz DK, White MJ, Schlievert PM, Horswill AR.

mSphere. 2016 Oct 12;1(5). pii: e00208-16. eCollection 2016 Sep-Oct.

37.

Lentiviral-mediated phenotypic correction of cystic fibrosis pigs.

Cooney AL, Abou Alaiwa MH, Shah VS, Bouzek DC, Stroik MR, Powers LS, Gansemer ND, Meyerholz DK, Welsh MJ, Stoltz DA, Sinn PL, McCray PB Jr.

JCI Insight. 2016 Sep 8;1(14). pii: e88730.

38.

Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet.

Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA.

Obesity (Silver Spring). 2016 Oct;24(10):2140-9. doi: 10.1002/oby.21620. Epub 2016 Aug 12.

39.

Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses.

Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S.

Immunity. 2016 Jun 21;44(6):1379-91. doi: 10.1016/j.immuni.2016.05.006. Epub 2016 Jun 7.

40.

Lessons learned from the cystic fibrosis pig.

Meyerholz DK.

Theriogenology. 2016 Jul 1;86(1):427-32. doi: 10.1016/j.theriogenology.2016.04.057. Epub 2016 Apr 21. Review.

41.

Animal models: Software for study design falls short.

Meyerholz DK, Piersigilli A.

Nature. 2016 Apr 14;532(7598):177. doi: 10.1038/532177c. No abstract available.

PMID:
27075088
42.

Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection.

Ibberson CB, Parlet CP, Kwiecinski J, Crosby HA, Meyerholz DK, Horswill AR.

Infect Immun. 2016 May 24;84(6):1917-1929. doi: 10.1128/IAI.01418-15. Print 2016 Jun.

43.

Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus.

Bartlett JA, Ramachandran S, Wohlford-Lenane CL, Barker CK, Pezzulo AA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA, McCray PB Jr.

Am J Respir Crit Care Med. 2016 Oct 1;194(7):845-854.

44.

Modeling Emergent Diseases: Lessons From Middle East Respiratory Syndrome.

Meyerholz DK.

Vet Pathol. 2016 May;53(3):517-8. doi: 10.1177/0300985816634811. Epub 2016 Mar 21. No abstract available.

PMID:
27000399
45.

The "Naked Truth": Naked Mole-Rats Do Get Cancer.

Piersigilli A, Meyerholz DK.

Vet Pathol. 2016 May;53(3):519-20. doi: 10.1177/0300985816638431. Epub 2016 Mar 21. No abstract available.

PMID:
27000397
46.

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice.

Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, Perlman S.

Cell Host Microbe. 2016 Feb 10;19(2):181-93. doi: 10.1016/j.chom.2016.01.007.

47.

Computed Tomography and Magnetic Resonance Imaging for Longitudinal Characterization of Lung Structure Changes in a Yucatan Miniature Pig Silicosis Model.

Hammond E, Newell JD Jr, Dilger SK, Stoyles N, Morgan J, Sieren JP, Thedens DR, Hoffman EA, Meyerholz DK, Sieren JC.

Toxicol Pathol. 2016 Apr;44(3):373-81. doi: 10.1177/0192623315622303. Epub 2016 Feb 2.

48.

Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ.

Science. 2016 Jan 29;351(6272):503-7. doi: 10.1126/science.aad5589.

49.

Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense.

Li X, Tang XX, Vargas Buonfiglio LG, Comellas AP, Thornell IM, Ramachandran S, Karp PH, Taft PJ, Sheets K, Abou Alaiwa MH, Welsh MJ, Meyerholz DK, Stoltz DA, Zabner J.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L670-9. doi: 10.1152/ajplung.00422.2015. Epub 2016 Jan 22.

50.

Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome.

Meyerholz DK, Lambertz AM, McCray PB Jr.

Am J Pathol. 2016 Jan;186(1):78-86. doi: 10.1016/j.ajpath.2015.09.014. Epub 2015 Nov 18.

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