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Items: 1 to 50 of 63

1.

Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial Heterogeneity.

Schmiesing J, Storch S, Dörfler AC, Schweizer M, Makrypidi-Fraune G, Thelen M, Sylvester M, Gieselmann V, Meyer-Schwesinger C, Koch-Nolte F, Tidow H, Mühlhausen C, Waheed A, Sly WS, Braulke T.

Cell Rep. 2018 Sep 11;24(11):2946-2956. doi: 10.1016/j.celrep.2018.08.014.

2.

The chemokine receptor CX3CR1 reduces renal injury in mice with angiotensin II induced hypertension.

Ahadzadeh E, Rosendahl A, Czesla D, Steffens P, Prüßner L, Meyer-Schwesinger C, Wanner N, Paust HJ, Huber TB, Stahl RA, Wiech T, Kurts C, Seniuk A, Ehmke H, Wenzel UO.

Am J Physiol Renal Physiol. 2018 Sep 12. doi: 10.1152/ajprenal.00149.2018. [Epub ahead of print]

PMID:
30207169
3.

Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition.

Kumar V, Vashistha H, Lan X, Chandel N, Ayasolla K, Shoshtari SSM, Aslam R, Paliwal N, Abbruscato F, Mikulak J, Popik W, Atta MG, Chander PN, Malhotra A, Meyer-Schwesinger C, Skorecki K, Singhal PC.

Am J Pathol. 2018 Nov;188(11):2508-2528. doi: 10.1016/j.ajpath.2018.07.025. Epub 2018 Sep 8.

4.

Glomerular endothelial cell maturation depends on ADAM10, a key regulator of Notch signaling.

Farber G, Hurtado R, Loh S, Monette S, Mtui J, Kopan R, Quaggin S, Meyer-Schwesinger C, Herzlinger D, Scott RP, Blobel CP.

Angiogenesis. 2018 May;21(2):335-347. doi: 10.1007/s10456-018-9599-4. Epub 2018 Feb 3.

PMID:
29397483
5.

A Heterologous Model of Thrombospondin Type 1 Domain-Containing 7A-Associated Membranous Nephropathy.

Tomas NM, Meyer-Schwesinger C, von Spiegel H, Kotb AM, Zahner G, Hoxha E, Helmchen U, Endlich N, Koch-Nolte F, Stahl RAK.

J Am Soc Nephrol. 2017 Nov;28(11):3262-3277. doi: 10.1681/ASN.2017010030. Epub 2017 Aug 16.

6.

Ubiquitin C-Terminal Hydrolase L1 is required for regulated protein degradation through the ubiquitin proteasome system in kidney.

Radón V, Czesla M, Reichelt J, Fehlert J, Hammel A, Rosendahl A, Knop JH, Wiech T, Wenzel UO, Sachs M, Reinicke AT, Stahl RAK, Meyer-Schwesinger C.

Kidney Int. 2018 Jan;93(1):110-127. doi: 10.1016/j.kint.2017.05.016. Epub 2017 Jul 26.

PMID:
28754552
7.

A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease.

Haase R, Potthoff SA, Meyer-Schwesinger C, Frosch C, Wiech T, Panzer U, Königshausen E, Stegbauer J, Sellin L, Rump LC, Quack I, Woznowski M.

PLoS One. 2017 Jun 12;12(6):e0179217. doi: 10.1371/journal.pone.0179217. eCollection 2017.

8.

IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis.

Riedel JH, Becker M, Kopp K, Düster M, Brix SR, Meyer-Schwesinger C, Kluth LA, Gnirck AC, Attar M, Krohn S, Fehse B, Stahl RAK, Panzer U, Turner JE.

J Am Soc Nephrol. 2017 Jul;28(7):2068-2080. doi: 10.1681/ASN.2016080877. Epub 2017 Feb 2.

9.

Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.

Danquah W, Meyer-Schwesinger C, Rissiek B, Pinto C, Serracant-Prat A, Amadi M, Iacenda D, Knop JH, Hammel A, Bergmann P, Schwarz N, Assunção J, Rotthier W, Haag F, Tolosa E, Bannas P, Boué-Grabot E, Magnus T, Laeremans T, Stortelers C, Koch-Nolte F.

Sci Transl Med. 2016 Nov 23;8(366):366ra162.

PMID:
27881823
10.

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney.

Krebs CF, Paust HJ, Krohn S, Koyro T, Brix SR, Riedel JH, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch P, Mittrücker HW, Steinhoff U, Stockinger B, Perez LG, Wenzel UO, Janneck M, Steinmetz OM, Gagliani N, Stahl RAK, Huber S, Turner JE, Panzer U.

Immunity. 2016 Nov 15;45(5):1078-1092. doi: 10.1016/j.immuni.2016.10.020.

11.

An Indirect Immunofluorescence Method Facilitates Detection of Thrombospondin Type 1 Domain-Containing 7A-Specific Antibodies in Membranous Nephropathy.

Hoxha E, Beck LH Jr, Wiech T, Tomas NM, Probst C, Mindorf S, Meyer-Schwesinger C, Zahner G, Stahl PR, Schöpper R, Panzer U, Harendza S, Helmchen U, Salant DJ, Stahl RA.

J Am Soc Nephrol. 2017 Feb;28(2):520-531. doi: 10.1681/ASN.2016010050. Epub 2016 Jul 19.

12.

Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy.

Tomas NM, Hoxha E, Reinicke AT, Fester L, Helmchen U, Gerth J, Bachmann F, Budde K, Koch-Nolte F, Zahner G, Rune G, Lambeau G, Meyer-Schwesinger C, Stahl RA.

J Clin Invest. 2016 Jul 1;126(7):2519-32. doi: 10.1172/JCI85265. Epub 2016 May 23.

13.

A Mechanism for Cancer-Associated Membranous Nephropathy.

Hoxha E, Wiech T, Stahl PR, Zahner G, Tomas NM, Meyer-Schwesinger C, Wenzel U, Janneck M, Steinmetz OM, Panzer U, Harendza S, Stahl RA.

N Engl J Med. 2016 May 19;374(20):1995-6. doi: 10.1056/NEJMc1511702. No abstract available.

14.

The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension.

Weiss S, Rosendahl A, Czesla D, Meyer-Schwesinger C, Stahl RA, Ehmke H, Kurts C, Zipfel PF, Köhl J, Wenzel UO.

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1356-65. doi: 10.1152/ajprenal.00040.2016. Epub 2016 Apr 6.

15.

Immune Complex-Type Deposits in the Fischer-344 to Lewis Rat Model of Renal Transplantation and a Subset of Human Transplant Glomerulopathy.

Grau V, Zeuschner P, Immenschuh S, Bockmeyer CL, Zell S, Wittig J, Säuberlich K, Abbas M, Padberg W, Meyer-Schwesinger C, von Brandenstein M, Schlosser M, Dieplinger G, Galliford J, Clarke C, Roufosse C, Becker JU.

Transplantation. 2016 May;100(5):1004-14. doi: 10.1097/TP.0000000000001068.

PMID:
26895216
16.

The Role of Renal Progenitors in Renal Regeneration.

Meyer-Schwesinger C.

Nephron. 2016;132(2):101-9. doi: 10.1159/000442180. Epub 2016 Jan 16. Review.

17.

CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.

Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U.

J Am Soc Nephrol. 2016 Jul;27(7):1933-42. doi: 10.1681/ASN.2015020203. Epub 2015 Nov 3.

18.

Treg17 cells are programmed by Stat3 to suppress Th17 responses in systemic lupus.

Kluger MA, Melderis S, Nosko A, Goerke B, Luig M, Meyer MC, Turner JE, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

Kidney Int. 2016 Jan;89(1):158-66. doi: 10.1038/ki.2015.296. Epub 2016 Jan 4.

PMID:
26466322
19.

TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis.

Hünemörder S, Treder J, Ahrens S, Schumacher V, Paust HJ, Menter T, Matthys P, Kamradt T, Meyer-Schwesinger C, Panzer U, Hopfer H, Mittrücker HW.

J Pathol. 2015 Sep;237(1):62-71. doi: 10.1002/path.4559. Epub 2015 Jun 11.

PMID:
25965582
20.

CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation.

Schneider M, Schumacher V, Lischke T, Lücke K, Meyer-Schwesinger C, Velden J, Koch-Nolte F, Mittrücker HW.

PLoS One. 2015 May 4;10(5):e0126007. doi: 10.1371/journal.pone.0126007. eCollection 2015.

21.

Glomerulopathy induced by immunization with a peptide derived from the goodpasture antigen α3IV-NC1.

Hopfer H, Hünemörder S, Treder J, Turner JE, Paust HJ, Meyer-Schwesinger C, Hopfer U, Sachs M, Peters A, Bucher-Kocaoglu B, Ahrens S, Panzer U, Mittrücker HW.

J Immunol. 2015 Apr 15;194(8):3646-55. doi: 10.4049/jimmunol.1401267. Epub 2015 Mar 13.

22.

Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy.

Meyer-Schwesinger C, Lambeau G, Stahl RA.

N Engl J Med. 2015 Mar 12;372(11):1074-5. doi: 10.1056/NEJMc1500130. No abstract available.

23.

Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy.

Tomas NM, Beck LH Jr, Meyer-Schwesinger C, Seitz-Polski B, Ma H, Zahner G, Dolla G, Hoxha E, Helmchen U, Dabert-Gay AS, Debayle D, Merchant M, Klein J, Salant DJ, Stahl RAK, Lambeau G.

N Engl J Med. 2014 Dec 11;371(24):2277-2287. doi: 10.1056/NEJMoa1409354. Epub 2014 Nov 13.

24.

MicroRNA-193a Regulates the Transdifferentiation of Human Parietal Epithelial Cells toward a Podocyte Phenotype.

Kietzmann L, Guhr SS, Meyer TN, Ni L, Sachs M, Panzer U, Stahl RA, Saleem MA, Kerjaschki D, Gebeshuber CA, Meyer-Schwesinger C.

J Am Soc Nephrol. 2015 Jun;26(6):1389-401. doi: 10.1681/ASN.2014020190. Epub 2014 Sep 30.

25.

Myeloperoxidase deficiency ameliorates progression of chronic kidney disease in mice.

Lehners A, Lange S, Niemann G, Rosendahl A, Meyer-Schwesinger C, Oh J, Stahl R, Ehmke H, Benndorf R, Klinke A, Baldus S, Wenzel UO.

Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F407-17. doi: 10.1152/ajprenal.00262.2014. Epub 2014 Jul 2.

26.

CXCL5 drives neutrophil recruitment in TH17-mediated GN.

Disteldorf EM, Krebs CF, Paust HJ, Turner JE, Nouailles G, Tittel A, Meyer-Schwesinger C, Stege G, Brix S, Velden J, Wiech T, Helmchen U, Steinmetz OM, Peters A, Bennstein SB, Kaffke A, Llanto C, Lira SA, Mittrücker HW, Stahl RA, Kurts C, Kaufmann SH, Panzer U.

J Am Soc Nephrol. 2015 Jan;26(1):55-66. doi: 10.1681/ASN.2013101061. Epub 2014 Jun 5.

27.

Alterations in the ubiquitin proteasome system in persistent but not reversible proteinuric diseases.

Beeken M, Lindenmeyer MT, Blattner SM, Radón V, Oh J, Meyer TN, Hildebrand D, Schlüter H, Reinicke AT, Knop JH, Vivekanandan-Giri A, Münster S, Sachs M, Wiech T, Pennathur S, Cohen CD, Kretzler M, Stahl RA, Meyer-Schwesinger C.

J Am Soc Nephrol. 2014 Nov;25(11):2511-25. doi: 10.1681/ASN.2013050522. Epub 2014 Apr 10.

28.

UCH-L1 induces podocyte hypertrophy in membranous nephropathy by protein accumulation.

Lohmann F, Sachs M, Meyer TN, Sievert H, Lindenmeyer MT, Wiech T, Cohen CD, Balabanov S, Stahl RA, Meyer-Schwesinger C.

Biochim Biophys Acta. 2014 Jul;1842(7):945-58. doi: 10.1016/j.bbadis.2014.02.011. Epub 2014 Feb 28.

29.

CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.

Nouailles G, Dorhoi A, Koch M, Zerrahn J, Weiner J 3rd, Faé KC, Arrey F, Kuhlmann S, Bandermann S, Loewe D, Mollenkopf HJ, Vogelzang A, Meyer-Schwesinger C, Mittrücker HW, McEwen G, Kaufmann SH.

J Clin Invest. 2014 Mar;124(3):1268-82. doi: 10.1172/JCI72030. Epub 2014 Feb 10.

30.

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium.

Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl JM, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, Bernhagen J, Bucala R, Panzer U, Kolanus W, Gröne HJ, Garbi N, Kastenmüller W, Knolle PA, Kurts C, Engel DR.

Cell. 2014 Jan 30;156(3):456-68. doi: 10.1016/j.cell.2014.01.006.

31.

Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension.

Krebs CF, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl RA, Benndorf RA, Velden J, Paust HJ, Panzer U, Ehmke H, Wenzel UO.

Hypertension. 2014 Mar;63(3):565-71. doi: 10.1161/HYPERTENSIONAHA.113.02620. Epub 2013 Dec 23.

PMID:
24366079
32.

B-cell-derived IL-10 does not vitally contribute to the clinical course of glomerulonephritis.

Kluger MA, Ostmann A, Luig M, Meyer MC, Goerke B, Paust HJ, Meyer-Schwesinger C, Stahl RA, Panzer U, Tiegs G, Steinmetz OM.

Eur J Immunol. 2014 Mar;44(3):683-93. doi: 10.1002/eji.201343842. Epub 2013 Dec 16.

33.

The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis.

Sosna J, Voigt S, Mathieu S, Kabelitz D, Trad A, Janssen O, Meyer-Schwesinger C, Schütze S, Adam D.

Cell Commun Signal. 2013 Oct 3;11:76. doi: 10.1186/1478-811X-11-76.

34.

Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients.

Schröder C, Milde-Langosch K, Gebauer F, Schmid K, Mueller V, Wirtz RM, Meyer-Schwesinger C, Schlüter H, Sauter G, Schumacher U.

J Cancer Res Clin Oncol. 2013 Oct;139(10):1745-55. doi: 10.1007/s00432-013-1496-z. Epub 2013 Aug 31.

PMID:
23996067
35.

MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN.

Krebs CF, Kapffer S, Paust HJ, Schmidt T, Bennstein SB, Peters A, Stege G, Brix SR, Meyer-Schwesinger C, Müller RU, Turner JE, Steinmetz OM, Wolf G, Stahl RA, Panzer U.

J Am Soc Nephrol. 2013 Dec;24(12):1955-65. doi: 10.1681/ASN.2013020130. Epub 2013 Aug 15.

36.

Mouse models of membranous nephropathy: the road less travelled by.

Borza DB, Zhang JJ, Beck LH Jr, Meyer-Schwesinger C, Luo W.

Am J Clin Exp Immunol. 2013 Jun 15;2(2):135-45. Print 2013.

37.

Acute renal proximal tubule alterations during induced metabolic crises in a mouse model of glutaric aciduria type 1.

Thies B, Meyer-Schwesinger C, Lamp J, Schweizer M, Koeller DM, Ullrich K, Braulke T, Mühlhausen C.

Biochim Biophys Acta. 2013 Oct;1832(10):1463-72. doi: 10.1016/j.bbadis.2013.04.019. Epub 2013 Apr 24.

38.

The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation.

Guhr SS, Sachs M, Wegner A, Becker JU, Meyer TN, Kietzmann L, Schlossarek S, Carrier L, Braig M, Jat PS, Stahl RA, Meyer-Schwesinger C.

Kidney Int. 2013 Sep;84(3):532-44. doi: 10.1038/ki.2013.115. Epub 2013 Apr 24.

39.

Rho-kinase inhibition prevents proteinuria in immune-complex-mediated antipodocyte nephritis.

Meyer-Schwesinger C, Dehde S, Sachs M, Mathey S, Arefi K, Gatzemeier S, Balabanov S, Becker JU, Thaiss F, Meyer TN.

Am J Physiol Renal Physiol. 2012 Oct;303(7):F1015-25. doi: 10.1152/ajprenal.00380.2011. Epub 2012 Jul 18.

40.

IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.

Turner JE, Krebs C, Tittel AP, Paust HJ, Meyer-Schwesinger C, Bennstein SB, Steinmetz OM, Prinz I, Magnus T, Korn T, Stahl RA, Kurts C, Panzer U.

J Am Soc Nephrol. 2012 Sep;23(9):1486-95. doi: 10.1681/ASN.2012010040. Epub 2012 Jul 12.

41.

Characterization of the renal CD4+ T-cell response in experimental autoimmune glomerulonephritis.

Hopfer H, Holzer J, Hünemörder S, Paust HJ, Sachs M, Meyer-Schwesinger C, Turner JE, Panzer U, Mittrücker HW.

Kidney Int. 2012 Jul;82(1):60-71. doi: 10.1038/ki.2012.73. Epub 2012 Mar 21.

42.

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation.

Ummanni R, Jost E, Braig M, Lohmann F, Mundt F, Barett C, Schlomm T, Sauter G, Senff T, Bokemeyer C, Sültmann H, Meyer-Schwesinger C, Brümmendorf TH, Balabanov S.

Mol Cancer. 2011 Oct 14;10:129. doi: 10.1186/1476-4598-10-129.

43.

Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis.

Meyer-Schwesinger C, Dehde S, Klug P, Becker JU, Mathey S, Arefi K, Balabanov S, Venz S, Endlich KH, Pekna M, Gessner JE, Thaiss F, Meyer TN.

J Immunol. 2011 Sep 15;187(6):3218-29. doi: 10.4049/jimmunol.1003451. Epub 2011 Aug 15.

44.

Ubiquitin C-terminal hydrolase-l1 activity induces polyubiquitin accumulation in podocytes and increases proteinuria in rat membranous nephropathy.

Meyer-Schwesinger C, Meyer TN, Sievert H, Hoxha E, Sachs M, Klupp EM, Münster S, Balabanov S, Carrier L, Helmchen U, Thaiss F, Stahl RA.

Am J Pathol. 2011 May;178(5):2044-57. doi: 10.1016/j.ajpath.2011.01.017.

45.

Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats.

Meyer-Schwesinger C, Lange C, Bröcker V, Agustian P, Lehmann U, Raabe A, Brinkmeyer M, Kobayashi E, Schiffer M, Büsche G, Kreipe HH, Thaiss F, Becker JU.

Am J Pathol. 2011 Feb;178(2):494-9. doi: 10.1016/j.ajpath.2010.10.024. Erratum in: Am J Pathol. 2011 Jul;179(1):537. Andina Agustian, Putri [corrected to Agustian, Putri Andina].

46.

CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes.

Tossidou I, Teng B, Drobot L, Meyer-Schwesinger C, Worthmann K, Haller H, Schiffer M.

J Biol Chem. 2010 Aug 13;285(33):25285-95. doi: 10.1074/jbc.M109.087239. Epub 2010 May 10.

47.

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.

Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB.

J Clin Invest. 2010 Apr;120(4):1084-96. doi: 10.1172/JCI39492.

48.

CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.

Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U.

J Immunol. 2009 Oct 1;183(7):4693-704. doi: 10.4049/jimmunol.0802626. Epub 2009 Sep 4.

49.

The instructive role of metanephric mesenchyme in ureteric bud patterning, sculpting, and maturation and its potential ability to buffer ureteric bud branching defects.

Shah MM, Tee JB, Meyer T, Meyer-Schwesinger C, Choi Y, Sweeney DE, Gallegos TF, Johkura K, Rosines E, Kouznetsova V, Rose DW, Bush KT, Sakurai H, Nigam SK.

Am J Physiol Renal Physiol. 2009 Nov;297(5):F1330-41. doi: 10.1152/ajprenal.00125.2009. Epub 2009 Sep 2. Erratum in: Am J Physiol Renal Physiol. 2010 May;298(5):F1285.

50.

Alterations of the podocyte proteome in response to high glucose concentrations.

Schordan S, Schordan E, Endlich N, Lindenmeyer MT, Meyer-Schwesinger C, Meyer TN, Giebel J, Cohen CD, Endlich K, Maurer MH.

Proteomics. 2009 Oct;9(19):4519-28. doi: 10.1002/pmic.200800214.

PMID:
19688724

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