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High level MYC amplification in B-cell lymphomas: is it a marker of aggressive disease?

Pophali PA, Marinelli LM, Ketterling RP, Meyer RG, McPhail ED, Kurtin PJ, Mwangi R, Maurer MJ, Habermann T, King RL.

Blood Cancer J. 2020 Jan 13;10(1):5. doi: 10.1038/s41408-019-0271-z.


Clinical utility of fluorescence in situ hybridization-based diagnosis of BCR-ABL1 like (Philadelphia chromosome like) B-acute lymphoblastic leukemia.

Anagnostou T, Knudson RA, Pearce KE, Meyer RG, Pitel BA, Peterson JF, Baughn LB, Reichard KK, Ketterling RP, Kloft-Nelson SM, Knutson DL, Khan SP, Gangat N, Litzow MR, Hogan WJ, Wolanskyj A, Al-Kali A, Begna KH, Elliott M, Pardanani A, Foran J, Shah M, Tefferi A, Alkhateeb H, Halling K, Rodriguez V, Greipp PT, Patnaik MM.

Am J Hematol. 2020 Mar;95(3):E68-E72. doi: 10.1002/ajh.25729. Epub 2020 Jan 26. No abstract available.


Working Up Group 4 Equivocal HER2 Samples Tested by Fluorescence in Situ Hybridization in a Reference Laboratory Setting: Past, Present, and Future.

Geiersbach KB, Meyer RG, Sill DR, Mounajjed T, Chen B, Sukov WR, Jenkins RB.

J Clin Oncol. 2020 Jan 10;38(2):175-176. doi: 10.1200/JCO.19.02482. Epub 2019 Nov 26. No abstract available.


Fluorescence in-situ hybridisation for TP63 rearrangements in T cell lymphomas: single-site experience of 470 patients and implications for clinical testing.

Peterson JF, Pearce KE, Meyer RG, Greipp PT, Knudson RA, Baughn LB, Ketterling RP, Feldman AL.

Histopathology. 2020 Feb;76(3):481-485. doi: 10.1111/his.14005. Epub 2020 Jan 17.


Effect of modified Soxhlet (Soxtec) and Folch extraction method selection on the total lipid determination of aged beef.

Holman BWB, Bailes KL, Meyer RG, Hopkins DL.

J Food Sci Technol. 2019 Aug;56(8):3957-3961. doi: 10.1007/s13197-019-03878-4. Epub 2019 Jun 24.


Whole Genome Mate-pair Sequencing of Plasma Cell Neoplasm as a Novel Diagnostic Strategy: A Case of Unrecognized t(2;11) Structural Variation.

Peterson JF, Meyer RG, Smoley SA, Webley M, Smadbeck JB, Vasmatzis G, Pearce K, Greipp PT, Ketterling RP, Craig FE, Stewart AK, Baughn LB.

Clin Lymphoma Myeloma Leuk. 2019 Sep;19(9):598-602. doi: 10.1016/j.clml.2019.06.006. Epub 2019 Jun 18. No abstract available.


In vitro effects of poly(ADP-ribose) polymerase inhibitors on the production of tumor necrosis factor-α by interferon- γ - and lipopolysaccharide-stimulated peripheral blood mononuclear cells of horses.

Cacciolatti C, Meyer-Ficca ML, Southwood LL, Meyer RG, Bertolotti L, Zarucco L.

Am J Vet Res. 2019 Jul;80(7):663-669. doi: 10.2460/ajvr.80.7.663.


Warthin-like Mucoepidermoid Carcinoma of the Parotid Gland: Unusual Morphology and Diagnostic Pitfalls.

Zhang D, Liao X, Tang Y, Meyer RG, VAN Dyke DL, Liu X, Islam MN, Lai J.

Anticancer Res. 2019 Jun;39(6):3213-3217. doi: 10.21873/anticanres.13461. Review.


Acute leukemias harboring KMT2A/MLLT10 fusion: a 10-year experience from a single genomics laboratory.

Peterson JF, Sukov WR, Pitel BA, Smoley SA, Pearce KE, Meyer RG, Williamson CM, Smadbeck JB, Vasmatzis G, Hoppman NL, Greipp PT, Baughn LB, Ketterling RP.

Genes Chromosomes Cancer. 2019 Aug;58(8):567-577. doi: 10.1002/gcc.22741. Epub 2019 Mar 19.


False-negative rates for MYC fluorescence in situ hybridization probes in B-cell neoplasms.

King RL, McPhail ED, Meyer RG, Vasmatzis G, Pearce K, Smadbeck JB, Ketterling RP, Smoley SA, Greipp PT, Hoppman NL, Peterson JF, Baughn LB.

Haematologica. 2019 Jun;104(6):e248-e251. doi: 10.3324/haematol.2018.207290. Epub 2018 Dec 6. No abstract available.


Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD+ Synthesis.

Palzer L, Bader JJ, Angel F, Witzel M, Blaser S, McNeil A, Wandersee MK, Leu NA, Lengner CJ, Cho CE, Welch KD, Kirkland JB, Meyer RG, Meyer-Ficca ML.

Cell Rep. 2018 Oct 30;25(5):1359-1370.e4. doi: 10.1016/j.celrep.2018.09.091.


Analysis of Common Abnormalities Seen in Chronic Lymphocytic Leukemia Using Fluorescence In Situ Hybridization.

Meyer RG, Van Dyke DL.

Methods Mol Biol. 2019;1881:35-49. doi: 10.1007/978-1-4939-8876-1_4.


KMT2A (MLL) rearrangements observed in pediatric/young adult T-lymphoblastic leukemia/lymphoma: A 10-year review from a single cytogenetic laboratory.

Peterson JF, Baughn LB, Pearce KE, Williamson CM, Benevides Demasi JC, Olson RM, Goble TA, Meyer RG, Greipp PT, Ketterling RP.

Genes Chromosomes Cancer. 2018 Nov;57(11):541-546. doi: 10.1002/gcc.22666. Epub 2018 Sep 10.


Assessment of Poly(ADP-ribose) Polymerase1 (PARP1) expression and activity in cells purified from blood and milk of dairy cattle.

De Matteis G, Reale A, Grandoni F, Meyer-Ficca ML, Scatà MC, Meyer RG, Buttazzoni L, Moioli B.

Vet Immunol Immunopathol. 2018 Aug;202:102-108. doi: 10.1016/j.vetimm.2018.06.013. Epub 2018 Jun 30.


Integrated Analysis of HER2 Copy Number by Cytogenomic Microarray in Breast Cancers With Nonclassical In Situ Hybridization Results.

Haskell GT, Liu YJ, Chen H, Chen B, Meyer RG, Yuhas JA, Geiersbach KB.

Am J Clin Pathol. 2018 Jan 29;149(2):135-147. doi: 10.1093/ajcp/aqx143.


Early histone H4 acetylation during chromatin remodeling in equine spermatogenesis.

Ketchum CC, Larsen CD, McNeil A, Meyer-Ficca ML, Meyer RG.

Biol Reprod. 2018 Jan 1;98(1):115-129. doi: 10.1093/biolre/iox159.


Heritable sperm chromatin epigenetics: a break to remember.

Meyer RG, Ketchum CC, Meyer-Ficca ML.

Biol Reprod. 2017 Jan 1;97(6):784-797. doi: 10.1093/biolre/iox137. Review.


Long-term survival of sorafenib-treated FLT3-ITD-positive acute myeloid leukaemia patients relapsing after allogeneic stem cell transplantation.

Metzelder SK, Schroeder T, Lübbert M, Ditschkowski M, Götze K, Scholl S, Meyer RG, Dreger P, Basara N, Fey MF, Salih HR, Finck A, Pabst T, Giagounidis A, Kobbe G, Wollmer E, Finke J, Neubauer A, Burchert A.

Eur J Cancer. 2017 Nov;86:233-239. doi: 10.1016/j.ejca.2017.09.016. Epub 2017 Oct 18.


Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease.

Cornely OA, Robertson MN, Haider S, Grigg A, Geddes M, Aoun M, Heinz WJ, Raad I, Schanz U, Meyer RG, Hammond SP, Mullane KM, Ostermann H, Ullmann AJ, Zimmerli S, Van Iersel MLPS, Hepler DA, Waskin H, Kartsonis NA, Maertens J.

J Antimicrob Chemother. 2017 Dec 1;72(12):3501. doi: 10.1093/jac/dkx382. No abstract available.


Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease.

Cornely OA, Robertson MN, Haider S, Grigg A, Geddes M, Aoun M, Heinz WJ, Raad I, Schanz U, Meyer RG, Hammond SP, Mullane KM, Ostermann H, Ullmann AJ, Zimmerli S, Van Iersel MLPS, Hepler DA, Waskin H, Kartsonis NA, Maertens J.

J Antimicrob Chemother. 2017 Dec 1;72(12):3406-3413. doi: 10.1093/jac/dkx263. Erratum in: J Antimicrob Chemother. 2017 Dec 1;72(12):3501.


A Rare Pediatric Example of Subcutaneous Extraskeletal Osteosarcoma: A Case Report and Review of the Morphologic Differential Diagnosis.

Zreik RT, Meyer RG, Jenkins RB, Norambuena GA, Fritchie KJ.

Am J Dermatopathol. 2016 Apr;38(4):e44-8. doi: 10.1097/DAD.0000000000000458. Review.


Allogeneic stem cell transplantation after conditioning with treosulfan, etoposide and cyclophosphamide for patients with ALL: a phase II-study on behalf of the German Cooperative Transplant Study Group and ALL Study Group (GMALL).

Kröger N, Bornhäuser M, Stelljes M, Pichlmeier U, Trenschel R, Schmid C, Arnold R, Martin H, Heinzelmann M, Wolschke C, Meyer RG, Bethge W, Kobbe G, Ayuk F, Gökbuget N, Hölzer D, Zander A, Beelen D.

Bone Marrow Transplant. 2015 Dec;50(12):1503-7. doi: 10.1038/bmt.2015.202. Epub 2015 Sep 14.


The activity and inhibition of poly(ADP-ribose) polymerase-1 in equine peripheral blood mononuclear cells in vitro.

Douglas HF, Southwood LL, Meyer-Ficca ML, Hart SK, Meyer RG.

J Vet Emerg Crit Care (San Antonio). 2015 Jul-Aug;25(4):528-37. doi: 10.1111/vec.12316. Epub 2015 Jun 3.


Characterization of BRD4 during mammalian postmeiotic sperm development.

Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL.

Mol Cell Biol. 2015 Apr;35(8):1433-48. doi: 10.1128/MCB.01328-14. Epub 2015 Feb 17.


Spermatid head elongation with normal nuclear shaping requires ADP-ribosyltransferase PARP11 (ARTD11) in mice.

Meyer-Ficca ML, Ihara M, Bader JJ, Leu NA, Beneke S, Meyer RG.

Biol Reprod. 2015 Mar;92(3):80. doi: 10.1095/biolreprod.114.123661. Epub 2015 Feb 11.


Rituximab combined with DexaBEAM followed by high dose therapy as salvage therapy in patients with relapsed or refractory B-cell lymphoma: mature results of a phase II multicentre study.

Kirschey S, Flohr T, Wolf HH, Frickhofen N, Gramatzki M, Link H, Basara N, Peter N, Meyer RG, Schmitz N, Weidmann E, Banat A, Schulz A, Kolbe K, Derigs G, Theobald M, Hess G.

Br J Haematol. 2015 Mar;168(6):824-34. doi: 10.1111/bjh.13234. Epub 2014 Dec 28.


Transmission of angioimmunoblastic T-cell lymphoma by bone marrow transplant.

Kreft A, Springer E, Geissinger E, Wagner EM, Bender K, Kolbe K, Hainz M, Rosenwald A, Herr W, Kirkpatrick CJ, Meyer RG.

Leuk Lymphoma. 2015 Apr;56(4):1164-7. doi: 10.3109/10428194.2014.949702. Epub 2014 Oct 9. No abstract available.


Paternal poly (ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression.

Ihara M, Meyer-Ficca ML, Leu NA, Rao S, Li F, Gregory BD, Zalenskaya IA, Schultz RM, Meyer RG.

PLoS Genet. 2014 May 8;10(5):e1004317. doi: 10.1371/journal.pgen.1004317. eCollection 2014 May.


Separation of spermatogenic cell types using STA-PUT velocity sedimentation.

Bryant JM, Meyer-Ficca ML, Dang VM, Berger SL, Meyer RG.

J Vis Exp. 2013 Oct 9;(80). doi: 10.3791/50648.


Human CD8+ memory and EBV-specific T cells show low alloreactivity in vitro and in CD34+ stem cell-engrafted NOD/SCID/IL-2Rγc null mice.

Thomas S, Klobuch S, Sommer M, van Ewijk R, Theobald M, Meyer RG, Herr W.

Exp Hematol. 2014 Jan;42(1):28-38.e1-2. doi: 10.1016/j.exphem.2013.09.013. Epub 2013 Oct 8.


Transplantation in follicular lymphoma: not "yes or no" but "whom and when".

Hess G, Meyer RG.

Haematologica. 2013 Sep;98(9):1333-4. doi: 10.3324/haematol.2013.091538. No abstract available.


Second allograft for hematologic relapse of acute leukemia after first allogeneic stem-cell transplantation from related and unrelated donors: the role of donor change.

Christopeit M, Kuss O, Finke J, Bacher U, Beelen DW, Bornhäuser M, Schwerdtfeger R, Bethge WA, Basara N, Gramatzki M, Tischer J, Kolb HJ, Uharek L, Meyer RG, Bunjes D, Scheid C, Martin H, Niederwieser D, Kröger N, Bertz H, Schrezenmeier H, Schmid C.

J Clin Oncol. 2013 Sep 10;31(26):3259-71. doi: 10.1200/JCO.2012.44.7961. Epub 2013 Aug 5.


Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation.

Meyer-Ficca ML, Lonchar JD, Ihara M, Bader JJ, Meyer RG.

Chromosoma. 2013 Aug;122(4):319-35. doi: 10.1007/s00412-013-0416-y. Epub 2013 Jun 1.


Current practice in diagnosis and treatment of acute graft-versus-host disease: results from a survey among German-Austrian-Swiss hematopoietic stem cell transplant centers.

Wolff D, Ayuk F, Elmaagacli A, Bertz H, Lawitschka A, Schleuning M, Meyer RG, Gerbitz A, Hilgendorf I, Hildebrandt GC, Edinger M, Klein S, Halter J, Mousset S, Holler E, Greinix HT.

Biol Blood Marrow Transplant. 2013 May;19(5):767-76. doi: 10.1016/j.bbmt.2013.01.018. Epub 2013 Jan 29.


Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse.

Pfeiffer T, Schleuning M, Mayer J, Haude KH, Tischer J, Buchholz S, Bunjes D, Bug G, Holler E, Meyer RG, Greinix H, Scheid C, Christopeit M, Schnittger S, Braess J, Schlimok G, Spiekermann K, Ganser A, Kolb HJ, Schmid C.

Haematologica. 2013 Apr;98(4):518-25. doi: 10.3324/haematol.2012.070235. Epub 2012 Sep 14.


Intronic promoters and their noncoding transcripts: a new source of cancer-associated genes.

Relle M, Becker M, Meyer RG, Stassen M, Schwarting A.

Mol Carcinog. 2014 Feb;53(2):117-24. doi: 10.1002/mc.21955. Epub 2012 Aug 28.


Improved extraction of saturated fatty acids but not omega-3 fatty acids from sheep red blood cells using a one-step extraction procedure.

Clayton EH, Gulliver CE, Piltz JW, Taylor RD, Blake RJ, Meyer RG.

Lipids. 2012 Jul;47(7):719-27. doi: 10.1007/s11745-012-3674-1. Epub 2012 May 10.


High activity of sorafenib in FLT3-ITD-positive acute myeloid leukemia synergizes with allo-immune effects to induce sustained responses.

Metzelder SK, Schroeder T, Finck A, Scholl S, Fey M, Götze K, Linn YC, Kröger M, Reiter A, Salih HR, Heinicke T, Stuhlmann R, Müller L, Giagounidis A, Meyer RG, Brugger W, Vöhringer M, Dreger P, Mori M, Basara N, Schäfer-Eckart K, Schultheis B, Baldus C, Neubauer A, Burchert A.

Leukemia. 2012 Nov;26(11):2353-9. doi: 10.1038/leu.2012.105. Epub 2012 Apr 16.


Varicella-zoster virus glycoproteins B and E are major targets of CD4+ and CD8+ T cells reconstituting during zoster after allogeneic transplantation.

Kleemann P, Distler E, Wagner EM, Thomas S, Klobuch S, Aue S, Schnürer E, Schild H, Theobald M, Plachter B, Tenzer S, Meyer RG, Herr W.

Haematologica. 2012 Jun;97(6):874-82. doi: 10.3324/haematol.2011.052597. Epub 2011 Dec 29.


Genetic approaches to targeting multiple PARP genes in a mammalian genome.

Meyer-Ficca ML, Meyer RG.

Methods Mol Biol. 2011;780:349-76. doi: 10.1007/978-1-61779-270-0_21.


Human epidermal Langerhans cells replenish skin xenografts and are depleted by alloreactive T cells in vivo.

Hemmerling J, Wegner-Kops J, von Stebut E, Wolff D, Wagner EM, Hartwig UF, André MC, Theobald M, Schopf RE, Herr W, Meyer RG.

J Immunol. 2011 Aug 1;187(3):1142-9. doi: 10.4049/jimmunol.1001491. Epub 2011 Jun 22.


Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.

Bermudez Y, Benavente CA, Meyer RG, Coyle WR, Jacobson MK, Jacobson EL.

PLoS One. 2011;6(5):e20487. doi: 10.1371/journal.pone.0020487. Epub 2011 May 31.


Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.

Meyer-Ficca ML, Lonchar JD, Ihara M, Meistrich ML, Austin CA, Meyer RG.

Biol Reprod. 2011 May;84(5):900-9. doi: 10.1095/biolreprod.110.090035. Epub 2011 Jan 12.


Addressing tumour tolerance to improve cancer immunotherapy.

Meyer RG, Herr W.

Eur J Immunol. 2010 Dec;40(12):3302-5. doi: 10.1002/eji.201090067. No abstract available.


Poly(ADP-ribose) metabolism is essential for proper nucleoprotein exchange during mouse spermiogenesis.

Meyer-Ficca ML, Ihara M, Lonchar JD, Meistrich ML, Austin CA, Min W, Wang ZQ, Meyer RG.

Biol Reprod. 2011 Feb;84(2):218-28. doi: 10.1095/biolreprod.110.087361. Epub 2010 Sep 29.


Leishmaniasis, contact hypersensitivity and graft-versus-host disease: understanding the role of dendritic cell subsets in balancing skin immunity and tolerance.

Kautz-Neu K, Meyer RG, Clausen BE, von Stebut E.

Exp Dermatol. 2010 Aug;19(8):760-71. doi: 10.1111/j.1600-0625.2010.01116.x.


Preservation of dendritic cell function upon labeling with amino functionalized polymeric nanoparticles.

Zupke O, Distler E, Baumann D, Strand D, Meyer RG, Landfester K, Herr W, Mailänder V.

Biomaterials. 2010 Sep;31(27):7086-95. doi: 10.1016/j.biomaterials.2010.05.073. Epub 2010 Jun 22.


A case of Down syndrome with mirror-image duplication of chromosome 21.

Ha TM, Nguyen VN, Lindor NM, Meyer RG, Rai R, Velagaleti GV.

Am J Med Genet A. 2010 Jun;152A(6):1580-2. doi: 10.1002/ajmg.a.33326. No abstract available.


Automated cellular imaging system III for assessing HER2 status in breast cancer specimens: development of a standardized scoring method that correlates with FISH.

Minot DM, Kipp BR, Root RM, Meyer RG, Reynolds CA, Nassar A, Henry MR, Clayton AC.

Am J Clin Pathol. 2009 Jul;132(1):133-8. doi: 10.1309/AJCPJV0SKAF2PCMY.


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