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Items: 1 to 50 of 280

1.

The metabolic fate of the two new psychoactive substances 2-aminoindane and N-methyl-2-aminoindane studied in vitro and in vivo to support drug testing.

Manier SK, Felske C, Eckstein N, Meyer MR.

Drug Test Anal. 2019 Oct 30. doi: 10.1002/dta.2699. [Epub ahead of print]

PMID:
31667988
2.

Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoring.

Wagmann L, Hemmer S, Caspar AT, Meyer MR.

Clin Chem Lab Med. 2019 Oct 30. pii: /j/cclm.ahead-of-print/cclm-2019-0763/cclm-2019-0763.xml. doi: 10.1515/cclm-2019-0763. [Epub ahead of print]

PMID:
31665111
3.

Studies on the in vitro and in vivo metabolism of the synthetic opioids U-51754, U-47931E, and methoxyacetylfentanyl using hyphenated high-resolution mass spectrometry.

Nordmeier F, Richter LHJ, Schmidt PH, Schaefer N, Meyer MR.

Sci Rep. 2019 Sep 24;9(1):13774. doi: 10.1038/s41598-019-50196-y.

4.

Nox1 downregulators: A new class of therapeutics.

Barton M, Meyer MR, Prossnitz ER.

Steroids. 2019 Sep 10;152:108494. doi: 10.1016/j.steroids.2019.108494. [Epub ahead of print]

PMID:
31518594
5.

Current Situation of the Metabolomics Techniques Used for the Metabolism Studies of New Psychoactive Substances.

Manier SK, Meyer MR.

Ther Drug Monit. 2019 Aug 14. doi: 10.1097/FTD.0000000000000694. [Epub ahead of print]

PMID:
31425443
6.

Toxicokinetics and analytical toxicology of the abused opioid U-48800 - in vitro metabolism, metabolic stability, isozyme mapping, and plasma protein binding.

Gampfer TM, Richter LHJ, Schäper J, Wagmann L, Meyer MR.

Drug Test Anal. 2019 Oct;11(10):1572-1580. doi: 10.1002/dta.2683. Epub 2019 Sep 10.

PMID:
31424163
7.

Evaluation of novel organosilane modifications of paper spray mass spectrometry substrates for analyzing polar compounds.

Bambauer TP, Maurer HH, Weber AA, Hannig M, Pütz N, Koch M, Manier SK, Schneider M, Meyer MR.

Talanta. 2019 Nov 1;204:677-684. doi: 10.1016/j.talanta.2019.05.095. Epub 2019 May 26.

PMID:
31357352
8.

Use of UPLC-HRMS/MS for In Vitro and In Vivo Metabolite Identification of Three Methylphenidate-derived New Psychoactive Substances.

Manier SK, Niedermeier S, Schäper J, Meyer MR.

J Anal Toxicol. 2019 Jul 26. pii: bkz052. doi: 10.1093/jat/bkz052. [Epub ahead of print]

PMID:
31355413
9.

Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings.

Wagmann L, Hempel N, Richter LHJ, Brandt SD, Stratford A, Meyer MR.

Drug Test Anal. 2019 Oct;11(10):1507-1521. doi: 10.1002/dta.2675. Epub 2019 Jul 31.

PMID:
31299701
10.

Distribution of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs.

Schaefer N, Kröll AK, Körbel C, Laschke MW, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Arch Toxicol. 2019 Aug;93(8):2211-2218. doi: 10.1007/s00204-019-02493-8. Epub 2019 Jun 21.

PMID:
31227841
11.

Earliest axial fossils from the genus Australopithecus.

Meyer MR, Williams SA.

J Hum Evol. 2019 Jul;132:189-214. doi: 10.1016/j.jhevol.2019.05.004. Epub 2019 May 30.

PMID:
31203847
12.

Development and application of a LC-HRMS/MS method for analyzing antihypertensive drugs in oral fluid for monitoring drug adherence.

Richter LHJ, Jacobs CM, Mahfoud F, Kindermann I, Böhm M, Meyer MR.

Anal Chim Acta. 2019 Sep 6;1070:69-79. doi: 10.1016/j.aca.2019.04.026. Epub 2019 Apr 15.

PMID:
31103169
13.

Current state of transfusion in traumatic brain injury and associated coagulopathy.

Stolla M, Zhang F, Meyer MR, Zhang J, Dong JF.

Transfusion. 2019 Apr;59(S2):1522-1528. doi: 10.1111/trf.15169. Review.

PMID:
30980753
15.

Sibship, physical activity, and sedentary behavior: a longitudinal, observational study among Mexican-heritage sibling dyads.

Ylitalo KR, Bridges CN, Gutierrez M, Sharkey JR, Meyer MRU.

BMC Public Health. 2019 Feb 14;19(1):191. doi: 10.1186/s12889-019-6521-y.

16.

Tools for studying the metabolism of new psychoactive substances for toxicological screening purposes - A comparative study using pooled human liver S9, HepaRG cells, and zebrafish larvae.

Richter LHJ, Herrmann J, Andreas A, Park YM, Wagmann L, Flockerzi V, Müller R, Meyer MR.

Toxicol Lett. 2019 May 1;305:73-80. doi: 10.1016/j.toxlet.2019.01.010. Epub 2019 Jan 22.

PMID:
30682400
17.

In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening procedures.

Wagmann L, Richter LHJ, Kehl T, Wack F, Bergstrand MP, Brandt SD, Stratford A, Maurer HH, Meyer MR.

Anal Bioanal Chem. 2019 Jul;411(19):4751-4763. doi: 10.1007/s00216-018-1558-9. Epub 2019 Jan 7.

PMID:
30617391
18.

Permissive Role of GPER for Arterial Hypertension.

Barton M, Meyer MR.

Hypertension. 2019 Feb;73(2):e9-e10. doi: 10.1161/HYPERTENSIONAHA.118.12159. No abstract available.

PMID:
30595124
19.

HuR-ry Up: How Hydrogen Sulfide Protects Against Atherosclerosis.

Barton M, Meyer MR.

Circulation. 2019 Jan 2;139(1):115-118. doi: 10.1161/CIRCULATIONAHA.118.036854. No abstract available.

PMID:
30592653
20.

Post-myocardial Infarction (MI) Care: Medication Adherence for Secondary Prevention After MI in a Large Real-world Population.

Huber CA, Meyer MR, Steffel J, Blozik E, Reich O, Rosemann T.

Clin Ther. 2019 Jan;41(1):107-117. doi: 10.1016/j.clinthera.2018.11.012. Epub 2018 Dec 24.

PMID:
30591287
21.
22.

Cytotoxicity of new psychoactive substances and other drugs of abuse studied in human HepG2 cells using an adopted high content screening assay.

Richter LHJ, Beck A, Flockerzi V, Maurer HH, Meyer MR.

Toxicol Lett. 2019 Feb;301:79-89. doi: 10.1016/j.toxlet.2018.11.007. Epub 2018 Nov 19.

PMID:
30465810
23.

Gender differences in patient and system delay for primary percutaneous coronary intervention: current trends in a Swiss ST-segment elevation myocardial infarction population.

Meyer MR, Bernheim AM, Kurz DJ, O'Sullivan CJ, Tüller D, Zbinden R, Rosemann T, Eberli FR.

Eur Heart J Acute Cardiovasc Care. 2019 Apr;8(3):283-290. doi: 10.1177/2048872618810410. Epub 2018 Nov 8.

PMID:
30406673
24.

Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases.

Wagmann L, Brandt SD, Stratford A, Maurer HH, Meyer MR.

Drug Test Anal. 2019 Feb;11(2):318-324. doi: 10.1002/dta.2494. Epub 2018 Sep 28.

PMID:
30188017
25.

Antidepressant effects of direct-acting antivirals against hepatitis C virus-Results from a pilot study.

Hahn D, Stokes CS, Kaiser R, Meyer MR, Lammert F, Gruenhage F.

Eur J Clin Invest. 2018 Dec;48(12):e13024. doi: 10.1111/eci.13024. Epub 2018 Sep 19.

PMID:
30175442
26.

Metabolic fate of the new synthetic cannabinoid 7'N-5F-ADB in rat, human, and pooled human S9 studied by means of hyphenated high-resolution mass spectrometry.

Richter LHJ, Maurer HH, Meyer MR.

Drug Test Anal. 2019 Feb;11(2):305-317. doi: 10.1002/dta.2493. Epub 2018 Oct 9.

PMID:
30160067
27.

Inhibition and stimulation of the human breast cancer resistance protein as in vitro predictor of drug-drug interactions of drugs of abuse.

Wagmann L, Maurer HH, Meyer MR.

Arch Toxicol. 2018 Sep;92(9):2875-2884. doi: 10.1007/s00204-018-2276-y. Epub 2018 Aug 6.

PMID:
30083819
28.

Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?

Schaefer N, Wojtyniak JG, Kroell AK, Koerbel C, Laschke MW, Lehr T, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Biochem Pharmacol. 2018 Sep;155:403-418. doi: 10.1016/j.bcp.2018.07.029. Epub 2018 Jul 24.

PMID:
30048626
29.
30.
31.

In vitro glucuronidation of designer benzodiazepines by human UDP-glucuronyltransferases.

Pettersson Bergstrand M, Richter LHJ, Maurer HH, Wagmann L, Meyer MR.

Drug Test Anal. 2019 Jan;11(1):45-50. doi: 10.1002/dta.2463. Epub 2018 Aug 9.

PMID:
29996009
32.

Screening For Pulmonary Hypertension With Multidetector Computed Tomography Among Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation.

O'Sullivan CJ, Montalbetti M, Zbinden R, Kurz DJ, Bernheim AM, Liew A, Meyer MR, Tüller D, Eberli FR.

Front Cardiovasc Med. 2018 Jun 5;5:63. doi: 10.3389/fcvm.2018.00063. eCollection 2018.

33.

Simple screening tools to identify limited health literacy in a low-income patient population.

Ylitalo KR, Meyer MRU, Lanning BA, During C, Laschober R, Griggs JO.

Medicine (Baltimore). 2018 Mar;97(10):e0110. doi: 10.1097/MD.0000000000010110.

34.

Publisher Correction: A new approach towards biomarker selection in estimation of human exposure to chiral chemicals: a case study of mephedrone.

Castrignanò E, Mardal M, Rydevik A, Miserez B, Ramsey J, Shine T, Pantoș GD, Meyer MR, Kasprzyk-Hordern B.

Sci Rep. 2018 Mar 6;8(1):4295. doi: 10.1038/s41598-018-22367-w.

35.

Neck function in early hominins and suspensory primates: Insights from the uncinate process.

Meyer MR, Woodward C, Tims A, Bastir M.

Am J Phys Anthropol. 2018 Jul;166(3):613-637. doi: 10.1002/ajpa.23448. Epub 2018 Feb 28.

PMID:
29492962
36.

Toxicokinetics of NPS: Update 2017.

Meyer MR.

Handb Exp Pharmacol. 2018;252:441-459. doi: 10.1007/164_2018_102. Review.

PMID:
29476337
37.

Development of an In-vitro Drug Delivery Efficiency Test for a Pulmonary Toxicokinetic Pig Study.

Schaefer N, Kroll AK, Laschke MW, Menger MD, Maurer HH, Meyer MR, Schmidt PH.

Curr Drug Deliv. 2018;15(8):1167-1171. doi: 10.2174/1567201815666180214130014.

PMID:
29446742
38.

Different in vitro and in vivo tools for elucidating the human metabolism of alpha-cathinone-derived drugs of abuse.

Manier SK, Richter LHJ, Schäper J, Maurer HH, Meyer MR.

Drug Test Anal. 2018 Jan 4. doi: 10.1002/dta.2355. [Epub ahead of print]

PMID:
29314710
39.

Human cytochrome P450 kinetic studies on six N-2-methoxybenzyl (NBOMe)-derived new psychoactive substances using the substrate depletion approach.

Caspar AT, Meyer MR, Maurer HH.

Toxicol Lett. 2018 Mar 15;285:1-8. doi: 10.1016/j.toxlet.2017.12.017. Epub 2017 Dec 23.

PMID:
29277574
40.

Publisher Correction: A new approach towards biomarker selection in estimation of human exposure to chiral chemicals: a case study of mephedrone.

Castrignanò E, Mardal M, Rydevik A, Miserez B, Ramsey J, Shine T, Pantoș GD, Meyer MR, Kasprzyk-Hordern B.

Sci Rep. 2017 Dec 22;7(1):18114. doi: 10.1038/s41598-017-18350-6.

41.

A new approach towards biomarker selection in estimation of human exposure to chiral chemicals: a case study of mephedrone.

Castrignanò E, Mardal M, Rydevik A, Miserez B, Ramsey J, Shine T, Pantoș GD, Meyer MR, Kasprzyk-Hordern B.

Sci Rep. 2017 Nov 2;7(1):13009. doi: 10.1038/s41598-017-12581-3. Erratum in: Sci Rep. 2017 Dec 22;7(1):18114. Sci Rep. 2018 Mar 6;8(1):4295.

42.
44.

Development of a quantitative approach in blood plasma for low-dosed hallucinogens and opioids using LC-high resolution mass spectrometry.

Caspar AT, Kollas AB, Maurer HH, Meyer MR.

Talanta. 2018 Jan 1;176:635-645. doi: 10.1016/j.talanta.2017.08.063. Epub 2017 Aug 23.

PMID:
28917801
45.

C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation.

Burel S, Coyan FC, Lorenzini M, Meyer MR, Lichti CF, Brown JH, Loussouarn G, Charpentier F, Nerbonne JM, Townsend RR, Maier LS, Marionneau C.

J Biol Chem. 2017 Oct 20;292(42):17431-17448. doi: 10.1074/jbc.M117.787788. Epub 2017 Sep 7.

49.

Dried urine spots - A novel sampling technique for comprehensive LC-MSn drug screening.

Michely JA, Meyer MR, Maurer HH.

Anal Chim Acta. 2017 Aug 22;982:112-121. doi: 10.1016/j.aca.2017.05.033. Epub 2017 Jun 14.

PMID:
28734350
50.

GPER Mediates Functional Endothelial Aging in Renal Arteries.

Meyer MR, Rosemann T, Barton M, Prossnitz ER.

Pharmacology. 2017;100(3-4):188-193. doi: 10.1159/000478732. Epub 2017 Jul 14.

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