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Items: 33


Benzoazepine-Fused Isoindolines via Intramolecular (3 + 2)-Cycloadditions of Azomethine Ylides with Dinitroarenes.

Wales SM, Rivinoja DJ, Gardiner MG, Bird MJ, Meyer AG, Ryan JH, Hyland CJT.

Org Lett. 2019 Jun 21;21(12):4703-4708. doi: 10.1021/acs.orglett.9b01580. Epub 2019 Jun 12.


mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition.

Xue G, Kohler R, Tang F, Hynx D, Wang Y, Orso F, Prêtre V, Ritschard R, Hirschmann P, Cron P, Roloff T, Dummer R, Mandalà M, Bichet S, Genoud C, Meyer AG, Muraro MG, Spagnoli GC, Taverna D, Rüegg C, Merghoub T, Massi D, Tang H, Levesque MP, Dirnhofer S, Zippelius A, Hemmings BA, Wicki A.

Oncotarget. 2017 May 25;8(41):69204-69218. doi: 10.18632/oncotarget.18213. eCollection 2017 Sep 19.


Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis.

Bahou KA, Braddock DC, Meyer AG, Savage GP.

Org Lett. 2017 Oct 6;19(19):5332-5335. doi: 10.1021/acs.orglett.7b02492. Epub 2017 Sep 21.


Lower Activation in Frontal Cortex and Posterior Cingulate Cortex Observed during Sex Determination Test in Early-Stage Dementia of the Alzheimer Type.

Rajmohan R, Anderson RC, Fang D, Meyer AG, Laengvejkal P, Julayanont P, Hannabas G, Linton K, Culberson J, Khan H, De Toledo J, Reddy PH, O'Boyle MW.

Front Aging Neurosci. 2017 May 22;9:156. doi: 10.3389/fnagi.2017.00156. eCollection 2017.


White Matter Deterioration May Foreshadow Impairment of Emotional Valence Determination in Early-Stage Dementia of the Alzheimer Type.

Rajmohan R, Anderson RC, Fang D, Meyer AG, Laengvejkal P, Julayanont P, Hannabas G, Linton K, Culberson J, Khan HM, De Toledo J, Reddy PH, O'Boyle M.

Front Aging Neurosci. 2017 Mar 1;9:37. doi: 10.3389/fnagi.2017.00037. eCollection 2017.


Molecular Markers for Pyrethrin Autoxidation in Stored Pyrethrum Crop: Analysis and Structure Determination.

Freemont JA, Littler SW, Hutt OE, Mauger S, Meyer AG, Winkler DA, Kerr MG, Ryan JH, Cole HF, Duggan PJ.

J Agric Food Chem. 2016 Sep 28;64(38):7134-41. doi: 10.1021/acs.jafc.6b02959. Epub 2016 Sep 19.


1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides with Carbonyl Dipolarophiles Yielding Oxazolidine Derivatives.

Meyer AG, Ryan JH.

Molecules. 2016 Jul 23;21(8). pii: E935. doi: 10.3390/molecules21080935. Review.


Functional Sites Induce Long-Range Evolutionary Constraints in Enzymes.

Jack BR, Meyer AG, Echave J, Wilke CO.

PLoS Biol. 2016 May 3;14(5):e1002452. doi: 10.1371/journal.pbio.1002452. eCollection 2016 May.


Time dependence of evolutionary metrics during the 2009 pandemic influenza virus outbreak.

Meyer AG, Spielman SJ, Bedford T, Wilke CO.

Virus Evol. 2015 Jan;1(1). pii: vev006. Epub 2015 Jan 1.


The utility of protein structure as a predictor of site-wise dN/dS varies widely among HIV-1 proteins.

Meyer AG, Wilke CO.

J R Soc Interface. 2015 Oct 6;12(111):20150579. doi: 10.1098/rsif.2015.0579.


Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses.

Kerr SA, Jackson EL, Lungu OI, Meyer AG, Demogines A, Ellington AD, Georgiou G, Wilke CO, Sawyer SL.

J Virol. 2015 Nov;89(22):11643-53. doi: 10.1128/JVI.01408-15. Epub 2015 Sep 9.


Geometric Constraints Dominate the Antigenic Evolution of Influenza H3N2 Hemagglutinin.

Meyer AG, Wilke CO.

PLoS Pathog. 2015 May 28;11(5):e1004940. doi: 10.1371/journal.ppat.1004940. eCollection 2015 May.


Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity.

Kachroo AH, Laurent JM, Yellman CM, Meyer AG, Wilke CO, Marcotte EM.

Science. 2015 May 22;348(6237):921-5. doi: 10.1126/science.aaa0769.


Predicting growth conditions from internal metabolic fluxes in an in-silico model of E. coli.

Sridhara V, Meyer AG, Rai P, Barrick JE, Ravikumar P, Segrè D, Wilke CO.

PLoS One. 2014 Dec 12;9(12):e114608. doi: 10.1371/journal.pone.0114608. eCollection 2014.


Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq.

Barrick JE, Colburn G, Deatherage DE, Traverse CC, Strand MD, Borges JJ, Knoester DB, Reba A, Meyer AG.

BMC Genomics. 2014 Nov 29;15:1039. doi: 10.1186/1471-2164-15-1039.


Predicting evolutionary site variability from structure in viral proteins: buriedness, packing, flexibility, and design.

Shahmoradi A, Sydykova DK, Spielman SJ, Jackson EL, Dawson ET, Meyer AG, Wilke CO.

J Mol Evol. 2014 Oct;79(3-4):130-42. doi: 10.1007/s00239-014-9644-x. Epub 2014 Sep 13.


Naturally occurring polyphenolic inhibitors of amyloid beta aggregation.

Churches QI, Caine J, Cavanagh K, Epa VC, Waddington L, Tranberg CE, Meyer AG, Varghese JN, Streltsov V, Duggan PJ.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3108-12. doi: 10.1016/j.bmcl.2014.05.008. Epub 2014 May 13.


An iterative in silico and modular synthetic approach to aqueous soluble tercyclic α-helix mimetics.

Lim Z, Duggan PJ, Meyer AG, Tuck KL.

Org Biomol Chem. 2014 Jul 7;12(25):4432-44. doi: 10.1039/c4ob00647j.


Analyzing machupo virus-receptor binding by molecular dynamics simulations.

Meyer AG, Sawyer SL, Ellington AD, Wilke CO.

PeerJ. 2014 Feb 27;2:e266. doi: 10.7717/peerj.266. eCollection 2014.


Maximum allowed solvent accessibilites of residues in proteins.

Tien MZ, Meyer AG, Sydykova DK, Spielman SJ, Wilke CO.

PLoS One. 2013 Nov 21;8(11):e80635. doi: 10.1371/journal.pone.0080635. eCollection 2013.


Alternate splicing of dysferlin C2A confers Ca²⁺-dependent and Ca²⁺-independent binding for membrane repair.

Fuson K, Rice A, Mahling R, Snow A, Nayak K, Shanbhogue P, Meyer AG, Redpath GM, Hinderliter A, Cooper ST, Sutton RB.

Structure. 2014 Jan 7;22(1):104-15. doi: 10.1016/j.str.2013.10.001. Epub 2013 Nov 14.


PeptideBuilder: A simple Python library to generate model peptides.

Tien MZ, Sydykova DK, Meyer AG, Wilke CO.

PeerJ. 2013 May 21;1:e80. doi: 10.7717/peerj.80. Print 2013.


Cross-species comparison of site-specific evolutionary-rate variation in influenza haemagglutinin.

Meyer AG, Dawson ET, Wilke CO.

Philos Trans R Soc Lond B Biol Sci. 2013 Feb 4;368(1614):20120334. doi: 10.1098/rstb.2012.0334. Print 2013 Mar 19.


Integrating sequence variation and protein structure to identify sites under selection.

Meyer AG, Wilke CO.

Mol Biol Evol. 2013 Jan;30(1):36-44. doi: 10.1093/molbev/mss217. Epub 2012 Sep 12.


Modeling coding-sequence evolution within the context of residue solvent accessibility.

Scherrer MP, Meyer AG, Wilke CO.

BMC Evol Biol. 2012 Sep 12;12:179. doi: 10.1186/1471-2148-12-179.


1,3-Dipolar cycloaddition-decarboxylation reactions of an azomethine ylide with isatoic anhydrides: formation of novel benzodiazepinones.

D'Souza AM, Spiccia N, Basutto J, Jokisz P, Wong LS, Meyer AG, Holmes AB, White JM, Ryan JH.

Org Lett. 2011 Feb 4;13(3):486-9. doi: 10.1021/ol102824k. Epub 2010 Dec 22.


Discovery of ectoparasiticidal hydrazonotrifluoromethanesulfonanilides.

Ali A, Fisara P, Freemont JA, Kyi S, Meyer AG, Riches AG, Sargent RM, Sawutz DG, Turner KA, Winzenberg KN, Yang Q.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):649-52. doi: 10.1016/j.bmcl.2009.11.054. Epub 2009 Dec 2.


Carboxymethylated-kappa-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation.

Carver JA, Duggan PJ, Ecroyd H, Liu Y, Meyer AG, Tranberg CE.

Bioorg Med Chem. 2010 Jan 1;18(1):222-8. doi: 10.1016/j.bmc.2009.10.063. Epub 2009 Nov 4.


Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro.

Aljofan M, Sganga ML, Lo MK, Rootes CL, Porotto M, Meyer AG, Saubern S, Moscona A, Mungall BA.

Virol J. 2009 Nov 4;6:187. doi: 10.1186/1743-422X-6-187.


Characteristics of Nipah virus and Hendra virus replication in different cell lines and their suitability for antiviral screening.

Aljofan M, Saubern S, Meyer AG, Marsh G, Meers J, Mungall BA.

Virus Res. 2009 Jun;142(1-2):92-9. doi: 10.1016/j.virusres.2009.01.014. Epub 2009 Jan 29.


Parasiticidal 2-alkoxy- and 2-aryloxyiminoalkyl trifluoromethanesulfonanilides.

Ali A, Altamore TM, Bliese M, Fisara P, Liepa AJ, Meyer AG, Nguyen O, Sargent RM, Sawutz DG, Winkler DA, Winzenberg KN, Ziebell A.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):252-5. Epub 2007 Oct 30.


Validation of hearing results in tympanoplasty: a preliminary report.

Meyer AG, Albers FW, De Visscher AV, Tenvergert EM.

Acta Otorhinolaryngol Belg. 1998;52(4):313-6.


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