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Items: 37

1.

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.

Duy C, Teater M, Garrett-Bakelman FE, Lee TC, Meydan C, Glass JL, Li M, Hellmuth JC, Mohammad HP, Smitheman KN, Shih AH, Abdel-Wahab O, Tallman MS, Guzman ML, Muench D, Grimes HL, Roboz GJ, Kruger RG, Creasy CL, Paietta EM, Levine RL, Carroll M, Melnick AM.

Cancer Discov. 2019 May 10. doi: 10.1158/2159-8290.CD-19-0106. [Epub ahead of print]

PMID:
31076479
2.

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW.

Science. 2019 Apr 12;364(6436). pii: eaau8650. doi: 10.1126/science.aau8650.

PMID:
30975860
3.

Growth Kinetics, Carbon Isotope Fractionation, and Gene Expression in the Hyperthermophile Methanocaldococcus jannaschii during Hydrogen-Limited Growth and Interspecies Hydrogen Transfer.

Topçuoğlu BD, Meydan C, Nguyen TB, Lang SQ, Holden JF.

Appl Environ Microbiol. 2019 Apr 18;85(9). pii: e00180-19. doi: 10.1128/AEM.00180-19. Print 2019 May 1.

4.

Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.

Agirre X, Meydan C, Jiang Y, Garate L, Doane AS, Li Z, Verma A, Paiva B, Martín-Subero JI, Elemento O, Mason CE, Prosper F, Melnick A.

Nat Commun. 2019 Feb 18;10(1):821. doi: 10.1038/s41467-019-08679-z.

5.

Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis.

Hatzi K, Geng H, Doane AS, Meydan C, LaRiviere R, Cardenas M, Duy C, Shen H, Vidal MNC, Baslan T, Mohammad HP, Kruger RG, Shaknovich R, Haberman AM, Inghirami G, Lowe SW, Melnick AM.

Nat Immunol. 2019 Jan;20(1):86-96. doi: 10.1038/s41590-018-0273-1. Epub 2018 Dec 10.

6.

Population-based data registries suggest novel insight into malignancy and metabolism.

Meydan C.

Cancer. 2019 Jan 1;125(1):15-17. doi: 10.1002/cncr.31762. Epub 2018 Nov 12. No abstract available.

PMID:
30417327
7.

Molecular Regulatory Pathways Link Sepsis With Metabolic Syndrome: Non-coding RNA Elements Underlying the Sepsis/Metabolic Cross-Talk.

Meydan C, Bekenstein U, Soreq H.

Front Mol Neurosci. 2018 Jun 5;11:189. doi: 10.3389/fnmol.2018.00189. eCollection 2018.

8.

ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2.

Jain D, Puno MR, Meydan C, Lailler N, Mason CE, Lima CD, Anderson KV, Keeney S.

Elife. 2018 Jan 23;7. pii: e30919. doi: 10.7554/eLife.30919.

9.

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.

Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, Maher R, Pronier E, Meyer SC, Garrett-Bakelman FE, Tallman M, Melnick A, Levine RL, Shih AH.

Cancer Cell. 2018 Jan 8;33(1):44-59.e8. doi: 10.1016/j.ccell.2017.11.012. Epub 2017 Dec 21.

10.

Formate hydrogenlyase and formate secretion ameliorate H2 inhibition in the hyperthermophilic archaeon Thermococcus paralvinellae.

Topçuoğlu BD, Meydan C, Orellana R, Holden JF.

Environ Microbiol. 2018 Mar;20(3):949-957. doi: 10.1111/1462-2920.14022. Epub 2017 Dec 29.

PMID:
29235714
11.

rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline.

Jain D, Meydan C, Lange J, Claeys Bouuaert C, Lailler N, Mason CE, Anderson KV, Keeney S.

PLoS Genet. 2017 Aug 30;13(8):e1006964. doi: 10.1371/journal.pgen.1006964. eCollection 2017 Aug.

12.

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.

Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, Kwon JA, Meydan C, Perales-Paton J, Arshi A, Gönen M, Famulare C, Patel M, Paietta E, Tallman MS, Lu Y, Glass J, Garret-Bakelman FE, Melnick A, Levine R, Al-Shahrour F, Järås M, Hacohen N, Hwang A, Garippa R, Lengner CJ, Armstrong SA, Cerchietti L, Cowley GS, Root D, Doench J, Leslie C, Ebert BL, Kharas MG.

Nat Genet. 2017 Jun;49(6):866-875. doi: 10.1038/ng.3854. Epub 2017 Apr 24.

13.

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.

Glass JL, Hassane D, Wouters BJ, Kunimoto H, Avellino R, Garrett-Bakelman FE, Guryanova OA, Bowman R, Redlich S, Intlekofer AM, Meydan C, Qin T, Fall M, Alonso A, Guzman ML, Valk PJM, Thompson CB, Levine R, Elemento O, Delwel R, Melnick A, Figueroa ME.

Cancer Discov. 2017 Aug;7(8):868-883. doi: 10.1158/2159-8290.CD-16-1032. Epub 2017 Apr 13.

14.

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.

Shih AH, Meydan C, Shank K, Garrett-Bakelman FE, Ward PS, Intlekofer AM, Nazir A, Stein EM, Knapp K, Glass J, Travins J, Straley K, Gliser C, Mason CE, Yen K, Thompson CB, Melnick A, Levine RL.

Cancer Discov. 2017 May;7(5):494-505. doi: 10.1158/2159-8290.CD-16-1049. Epub 2017 Feb 13.

15.

Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells.

Kunimoto H, McKenney AS, Meydan C, Shank K, Nazir A, Rapaport F, Durham B, Garrett-Bakelman FE, Pronier E, Shih AH, Melnick A, Chaudhuri J, Levine RL.

Blood. 2017 Mar 30;129(13):1779-1790. doi: 10.1182/blood-2016-06-721977. Epub 2017 Jan 11.

16.

Gastric Wall Thickness and the Choice of Linear Staples in Laparoscopic Sleeve Gastrectomy: Challenging Conventional Concepts.

Abu-Ghanem Y, Meydan C, Segev L, Rubin M, Blumenfeld O, Spivak H.

Obes Surg. 2017 Mar;27(3):837-843. doi: 10.1007/s11695-016-2516-2.

PMID:
28035523
17.

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.

Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre X, Teater M, Meydan C, Li Z, Poloway D, Wang S, Ennishi D, Scott DW, Stengel KR, Kranz JE, Holson E, Sharma S, Young JW, Chu CS, Roeder RG, Shaknovich R, Hiebert SW, Gascoyne RD, Tam W, Elemento O, Wendel HG, Melnick AM.

Cancer Discov. 2017 Jan;7(1):38-53. doi: 10.1158/2159-8290.CD-16-0975. Epub 2016 Oct 12.

18.

Reply to: "Biopsy of Paraganglioma and Takotsubo Syndrome".

Meydan C.

J Vasc Interv Radiol. 2016 Oct;27(10):1624-5. doi: 10.1016/j.jvir.2016.06.032. No abstract available.

PMID:
27670998
19.

Single Anastomosis Gastric Bypass-Comparative Short-Term Outcome Study of Conversional and Primary Procedures.

Meydan C, Raziel A, Sakran N, Gottfried V, Goitein D.

Obes Surg. 2017 Feb;27(2):432-438. doi: 10.1007/s11695-016-2336-4.

PMID:
27562250
20.

MicroRNA Regulators of Anxiety and Metabolic Disorders.

Meydan C, Shenhar-Tsarfaty S, Soreq H.

Trends Mol Med. 2016 Sep;22(9):798-812. doi: 10.1016/j.molmed.2016.07.001. Epub 2016 Aug 3. Review.

PMID:
27496210
21.

Takotsubo Cardiomyopathy Induced by CT-Guided Percutaneous Biopsy of a Paraganglioma.

Meydan C, Rimon U, Fefer P, Nissan A, Segev L.

J Vasc Interv Radiol. 2016 Jun;27(6):926-8. doi: 10.1016/j.jvir.2016.02.015. Epub 2016 Jun 3. No abstract available.

PMID:
27287974
22.

Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.

Afshinnekoo E, Meydan C, Chowdhury S, Jaroudi D, Boyer C, Bernstein N, Maritz JM, Reeves D, Gandara J, Chhangawala S, Ahsanuddin S, Simmons A, Nessel T, Sundaresh B, Pereira E, Jorgensen E, Kolokotronis SO, Kirchberger N, Garcia I, Gandara D, Dhanraj S, Nawrin T, Saletore Y, Alexander N, Vijay P, Hénaff EM, Zumbo P, Walsh M, O'Mullan GD, Tighe S, Dudley JT, Dunaif A, Ennis S, O'Halloran E, Magalhaes TR, Boone B, Jones AL, Muth TR, Paolantonio KS, Alter E, Schadt EE, Garbarino J, Prill RJ, Carlton JM, Levy S, Mason CE.

Cell Syst. 2015 Jul 29;1(1):97-97.e3. doi: 10.1016/j.cels.2015.07.006. Epub 2015 Jul 29. No abstract available.

23.

Modern Methods for Delineating Metagenomic Complexity.

Afshinnekoo E, Meydan C, Chowdhury S, Jaroudi D, Boyer C, Bernstein N, Maritz JM, Reeves D, Gandara J, Chhangawala S, Ahsanuddin S, Simmons A, Nessel T, Sundaresh B, Pereira E, Jorgensen E, Kolokotronis SO, Kirchberger N, Garcia I, Gandara D, Dhanraj S, Nawrin T, Saletore Y, Alexander N, Vijay P, Hénaff EM, Zumbo P, Walsh M, O'Mullan GD, Tighe S, Dudley JT, Dunaif A, Ennis S, O'Halloran E, Magalhaes TR, Boone B, Jones AL, Muth TR, Paolantonio KS, Alter E, Schadt EE, Garbarino J, Prill RJ, Carlton JM, Levy S, Mason CE.

Cell Syst. 2015 Jul 29;1(1):6-7. doi: 10.1016/j.cels.2015.07.007. Epub 2015 Jul 29. No abstract available.

24.

Achieving the "Minimal Scarring" Concept in Bariatrics by Port-Site Relocation.

Spivak H, Segev L, Meydan C, Yosef R, Ronen I, Heller L.

Obes Surg. 2016 Mar;26(3):683-7. doi: 10.1007/s11695-015-2019-6.

PMID:
26744283
25.

Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics.

Afshinnekoo E, Meydan C, Chowdhury S, Jaroudi D, Boyer C, Bernstein N, Maritz JM, Reeves D, Gandara J, Chhangawala S, Ahsanuddin S, Simmons A, Nessel T, Sundaresh B, Pereira E, Jorgensen E, Kolokotronis SO, Kirchberger N, Garcia I, Gandara D, Dhanraj S, Nawrin T, Saletore Y, Alexander N, Vijay P, Hénaff EM, Zumbo P, Walsh M, O'Mullan GD, Tighe S, Dudley JT, Dunaif A, Ennis S, O'Halloran E, Magalhaes TR, Boone B, Jones AL, Muth TR, Paolantonio KS, Alter E, Schadt EE, Garbarino J, Prill RJ, Carlton JM, Levy S, Mason CE.

Cell Syst. 2015 Jul 29;1(1):72-87. Epub 2015 Mar 3.

26.

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis.

Viny AD, Ott CJ, Spitzer B, Rivas M, Meydan C, Papalexi E, Yelin D, Shank K, Reyes J, Chiu A, Romin Y, Boyko V, Thota S, Maciejewski JP, Melnick A, Bradner JE, Levine RL.

J Exp Med. 2015 Oct 19;212(11):1819-32. doi: 10.1084/jem.20151317. Epub 2015 Oct 5.

27.

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.

Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason CE, Jaffrey SR.

Nat Methods. 2015 Aug;12(8):767-72. doi: 10.1038/nmeth.3453. Epub 2015 Jun 29.

28.

Immediate Metabolic Response Following Sleeve Gastrectomy in Obese Diabetics.

Meydan C, Goldstein N, Weiss-Shwartz E, Lederfine D, Goitein D, Rubin M, Spivak H.

Obes Surg. 2015 Nov;25(11):2023-9. doi: 10.1007/s11695-015-1669-8.

PMID:
25893648
29.

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.

Shih AH, Jiang Y, Meydan C, Shank K, Pandey S, Barreyro L, Antony-Debre I, Viale A, Socci N, Sun Y, Robertson A, Cavatore M, de Stanchina E, Hricik T, Rapaport F, Woods B, Wei C, Hatlen M, Baljevic M, Nimer SD, Tallman M, Paietta E, Cimmino L, Aifantis I, Steidl U, Mason C, Melnick A, Levine RL.

Cancer Cell. 2015 Apr 13;27(4):502-15. doi: 10.1016/j.ccell.2015.03.009.

30.

Managing the increasing shortage of acute care hospital beds in Israel.

Meydan C, Haklai Z, Gordon B, Mendlovic J, Afek A.

J Eval Clin Pract. 2015 Feb;21(1):79-84. doi: 10.1111/jep.12246. Epub 2014 Oct 14.

PMID:
25312266
31.

Cardiovascular and metabolic risk factors in inherited autoinflammation.

Twig G, Livneh A, Vivante A, Afek A, Derazne E, Leiba A, Shor DB, Meydan C, Ben-Zvi I, Tzur D, Furer A, Imazio M, Adler Y, Amital H.

J Clin Endocrinol Metab. 2014 Oct;99(10):E2123-8. doi: 10.1210/jc.2014-2096. Epub 2014 Jul 25.

PMID:
25062460
32.

Target-independent prediction of drug synergies using only drug lipophilicity.

Yilancioglu K, Weinstein ZB, Meydan C, Akhmetov A, Toprak I, Durmaz A, Iossifov I, Kazan H, Roth FP, Cokol M.

J Chem Inf Model. 2014 Aug 25;54(8):2286-93. doi: 10.1021/ci500276x. Epub 2014 Aug 1.

33.

Risk management--learning from the mistakes of others.

Meydan C.

J Eval Clin Pract. 2014 Aug;20(4):505-7. doi: 10.1111/jep.12165. Epub 2014 May 10. No abstract available.

PMID:
24815360
34.

The immigration effect on obesity and overweight in Israeli Jewish male adolescents born 1970-1993.

Meydan C, Twig G, Derazne E, Tzur D, Gordon B, Shamiss A, Afek A.

Ann Epidemiol. 2014 Jun;24(6):424-31. doi: 10.1016/j.annepidem.2014.02.012. Epub 2014 Mar 3.

PMID:
24698110
35.

Prediction of peptides binding to MHC class I and II alleles by temporal motif mining.

Meydan C, Otu HH, Sezerman OU.

BMC Bioinformatics. 2013;14 Suppl 2:S13. doi: 10.1186/1471-2105-14-S2-S13. Epub 2013 Jan 21.

36.

Testing robustness of relative complexity measure method constructing robust phylogenetic trees for Galanthus L. using the relative complexity measure.

Bakış Y, Otu HH, Taşçı N, Meydan C, Bilgin N, Yüzbaşıoğlu S, Sezerman OU.

BMC Bioinformatics. 2013 Jan 17;14:20. doi: 10.1186/1471-2105-14-20.

37.

Population-based trends in overweight and obesity: a comparative study of 2,148,342 Israeli male and female adolescents born 1950-1993.

Meydan C, Afek A, Derazne E, Tzur D, Twig G, Gordon B, Shamiss A.

Pediatr Obes. 2013 Apr;8(2):98-111. doi: 10.1111/j.2047-6310.2012.00096.x. Epub 2012 Sep 28.

PMID:
23019177

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