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Items: 1 to 50 of 298

1.

Alemtuzumab in Multiple Sclerosis: Short- and Long-Term Effects of Immunodepletion on the Peripheral Treg Compartment.

Haas J, Würthwein C, Korporal-Kuhnke M, Viehoever A, Jarius S, Ruck T, Pfeuffer S, Meuth SG, Wildemann B.

Front Immunol. 2019 Jun 4;10:1204. doi: 10.3389/fimmu.2019.01204. eCollection 2019.

PMID:
31214176
2.

CSF Neurofilament light chain level predicts axonal damage in cerebral vasculitis.

Pawlitzki M, Butryn M, Kirchner F, Färber J, Beuing O, Minnerup J, Meuth SG, Neumann J.

Ann Clin Transl Neurol. 2019 Jun 3;6(6):1134-1137. doi: 10.1002/acn3.790. eCollection 2019 Jun.

3.

An update on Peginterferon beta-1a Management in Multiple Sclerosis: results from an interdisciplinary Board of German and Austrian Neurologists and dermatologists.

Kolb-Mäurer A, Sunderkötter C, Kukowski B, Meuth SG; members of an expert meeting.

BMC Neurol. 2019 Jun 15;19(1):130. doi: 10.1186/s12883-019-1354-y.

4.

Seizures and epilepsy in multiple sclerosis: epidemiology and prognosis in a large tertiary referral center.

Langenbruch L, Krämer J, Güler S, Möddel G, Geßner S, Melzer N, Elger CE, Wiendl H, Budde T, Meuth SG, Kovac S.

J Neurol. 2019 May 8. doi: 10.1007/s00415-019-09332-x. [Epub ahead of print]

PMID:
31069528
5.

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.

Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H.

Sci Transl Med. 2019 May 1;11(490). pii: eaao5563. doi: 10.1126/scitranslmed.aao5563.

PMID:
31043571
6.

Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis.

Fleischer V, Koirala N, Droby A, Gracien RM, Deichmann R, Ziemann U, Meuth SG, Muthuraman M, Zipp F, Groppa S.

Ther Adv Neurol Disord. 2019 Apr 24;12:1756286419838673. doi: 10.1177/1756286419838673. eCollection 2019.

7.

Substance P Saliva Reduction Predicts Pharyngeal Dysphagia in Parkinson's Disease.

Schröder JB, Marian T, Claus I, Muhle P, Pawlowski M, Wiendl H, Suntrup-Krueger S, Meuth SG, Dziewas R, Ruck T, Warnecke T.

Front Neurol. 2019 Apr 16;10:386. doi: 10.3389/fneur.2019.00386. eCollection 2019.

8.

Immune Cell Profiling of the Cerebrospinal Fluid Provides Pathogenetic Insights Into Inflammatory Neuropathies.

Heming M, Schulte-Mecklenbeck A, Brix T, Wolbert J, Ruland T, Klotz L, Meuth SG, Gross CC, Wiendl H, Meyer Zu Hörste G.

Front Immunol. 2019 Mar 21;10:515. doi: 10.3389/fimmu.2019.00515. eCollection 2019.

9.

Glial Activation Markers in CSF and Serum From Patients With Primary Progressive Multiple Sclerosis: Potential of Serum GFAP as Disease Severity Marker?

Abdelhak A, Hottenrott T, Morenas-Rodríguez E, Suárez-Calvet M, Zettl UK, Haass C, Meuth SG, Rauer S, Otto M, Tumani H, Huss A.

Front Neurol. 2019 Mar 26;10:280. doi: 10.3389/fneur.2019.00280. eCollection 2019.

10.

Best Practices for Long-Term Monitoring and Follow-Up of Alemtuzumab-Treated MS Patients in Real-World Clinical Settings.

Barclay K, Carruthers R, Traboulsee A, Bass AD, LaGanke C, Bertolotto A, Boster A, Celius EG, de Seze J, Cruz DD, Habek M, Lee JM, Limmroth V, Meuth SG, Oreja-Guevara C, Pagnotta P, Vos C, Ziemssen T, Baker DP, Wijmeersch BV.

Front Neurol. 2019 Mar 22;10:253. doi: 10.3389/fneur.2019.00253. eCollection 2019. Review.

11.

Neuronal ICAM-5 Plays a Neuroprotective Role in Progressive Neurodegeneration.

Birkner K, Loos J, Gollan R, Steffen F, Wasser B, Ruck T, Meuth SG, Zipp F, Bittner S.

Front Neurol. 2019 Mar 12;10:205. doi: 10.3389/fneur.2019.00205. eCollection 2019.

12.

Isolation of Primary Murine Skeletal Muscle Microvascular Endothelial Cells.

Müntefering T, Michels APE, Pfeuffer S, Meuth SG, Ruck T.

J Vis Exp. 2019 Mar 6;(145). doi: 10.3791/58901.

PMID:
30907887
13.

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis.

Amedonu E, Brenker C, Barman S, Schreiber JA, Becker S, Peischard S, Strutz-Seebohm N, Strippel C, Dik A, Hartung HP, Budde T, Wiendl H, Strünker T, Wünsch B, Goebels N, Meuth SG, Seebohm G, Melzer N.

Front Neurol. 2019 Mar 1;10:178. doi: 10.3389/fneur.2019.00178. eCollection 2019.

14.

The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.

Zobeiri M, Chaudhary R, Blaich A, Rottmann M, Herrmann S, Meuth P, Bista P, Kanyshkova T, Lüttjohann A, Narayanan V, Hundehege P, Meuth SG, Romanelli MN, Urbano FJ, Pape HC, Budde T, Ludwig A.

Cereb Cortex. 2019 Mar 16. pii: bhz047. doi: 10.1093/cercor/bhz047. [Epub ahead of print]

15.

A fatal case of daclizumab-induced liver failure in a patient with MS.

Stettner M, Gross CC, Mausberg AK, Pul R, Junker A, Baba HA, Schulte-Mecklenbeck A, Wiendl H, Kleinschnitz C, Meuth SG.

Neurol Neuroimmunol Neuroinflamm. 2019 Jan 21;6(2):e539. doi: 10.1212/NXI.0000000000000539. eCollection 2019 Mar. No abstract available.

16.

Immune thrombocytopenia in alemtuzumab-treated MS patients: Incidence, detection, and management.

Cuker A, Bass AD, Nadj C, Agius MA, Steingo B, Selmaj KW, Thoits T, Guerreiro A, Van Wijmeersch B, Ziemssen T, Meuth SG, LaGanke CC, Thangavelu K, Rodriguez CE, Baker DP, Margolin DH, Jannsens A.

Mult Scler. 2019 Feb 20:1352458518816612. doi: 10.1177/1352458518816612. [Epub ahead of print]

PMID:
30785358
17.

Immunophenotyping of cerebrospinal fluid cells in ischaemic stroke.

Schulte-Mecklenbeck A, Kleffner I, Beuker C, Wirth T, Hartwig M, Schmidt-Pogoda A, Klotz L, Hansen W, Wiendl H, Meuth SG, Gross CC, Minnerup J.

Eur J Neurol. 2019 Jun;26(6):919-926. doi: 10.1111/ene.13909. Epub 2019 Feb 8.

PMID:
30659722
18.

CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration.

Pawlitzki M, Schreiber S, Bittner D, Kreipe J, Leypoldt F, Rupprecht K, Carare RO, Meuth SG, Vielhaber S, Körtvélyessy P.

Front Neurol. 2018 Dec 14;9:1037. doi: 10.3389/fneur.2018.01037. eCollection 2018.

19.

The K2P -channel TASK1 affects Oligodendroglial differentiation but not myelin restoration.

Albrecht S, Korr S, Nowack L, Narayanan V, Starost L, Stortz F, Araúzo-Bravo MJ, Meuth SG, Kuhlmann T, Hundehege P.

Glia. 2019 May;67(5):870-883. doi: 10.1002/glia.23577. Epub 2019 Jan 9.

PMID:
30623969
20.

Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease.

Schröder JB, Pawlowski M, Meyer Zu Hörste G, Gross CC, Wiendl H, Meuth SG, Ruck T, Warnecke T.

Front Neurol. 2018 Dec 18;9:1081. doi: 10.3389/fneur.2018.01081. eCollection 2018.

21.

Cell injury and receptor expression in the epileptic human amygdala.

Jafarian M, Modarres Mousavi SM, Alipour F, Aligholi H, Noorbakhsh F, Ghadipasha M, Gharehdaghi J, Kellinghaus C, Kovac S, Khaleghi Ghadiri M, Meuth SG, Speckmann EJ, Stummer W, Gorji A.

Neurobiol Dis. 2019 Apr;124:416-427. doi: 10.1016/j.nbd.2018.12.017. Epub 2018 Dec 24.

PMID:
30590180
22.

Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release.

Göbel K, Asaridou CM, Merker M, Eichler S, Herrmann AM, Geuß E, Ruck T, Schüngel L, Groeneweg L, Narayanan V, Schneider-Hohendorf T, Gross CC, Wiendl H, Kehrel BE, Kleinschnitz C, Meuth SG.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):271-276. doi: 10.1073/pnas.1810020116. Epub 2018 Dec 17.

PMID:
30559188
23.

TPP2 mutation associated with sterile brain inflammation mimicking MS.

Reinthaler EM, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill CM, Hoffjan S, Epplen JT, Zettl UK, Hecker M, Deutschländer A, Meuth SG, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick AD, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A.

Neurol Genet. 2018 Nov 13;4(6):e285. doi: 10.1212/NXG.0000000000000285. eCollection 2018 Dec.

24.

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).

Johnen A, Bürkner PC, Landmeyer NC, Ambrosius B, Calabrese P, Motte J, Hessler N, Antony G, König IR, Klotz L, Hoshi MM, Aly L, Groppa S, Luessi F, Paul F, Tackenberg B, Bergh FT, Kümpfel T, Tumani H, Stangel M, Weber F, Bayas A, Wildemann B, Heesen C, Zettl UK, Zipp F, Hemmer B, Meuth SG, Gold R, Wiendl H, Salmen A; German Competence Network Multiple Sclerosis (KKNMS).

J Neurol. 2019 Feb;266(2):386-397. doi: 10.1007/s00415-018-9142-y. Epub 2018 Dec 4.

25.

Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis.

Hundehege P, Fernandez-Orth J, Römer P, Ruck T, Müntefering T, Eichler S, Cerina M, Epping L, Albrecht S, Menke AF, Birkner K, Göbel K, Budde T, Zipp F, Wiendl H, Gorji A, Bittner S, Meuth SG.

Neurosignals. 2018;26(1):77-93. doi: 10.1159/000495425. Epub 2018 Nov 27. Review.

26.

CSF macrophage migration inhibitory factor levels did not predict steroid treatment response after optic neuritis in patients with multiple sclerosis.

Pawlitzki M, Sweeney-Reed CM, Meuth SG, Reinhold D, Neumann J.

PLoS One. 2018 Nov 26;13(11):e0207726. doi: 10.1371/journal.pone.0207726. eCollection 2018.

27.

Efficacy and safety of alemtuzumab versus fingolimod in RRMS after natalizumab cessation.

Pfeuffer S, Schmidt R, Straeten FA, Pul R, Kleinschnitz C, Wieshuber M, Lee DH, Linker RA, Doerck S, Straeten V, Windhagen S, Pawlitzki M, Aufenberg C, Lang M, Eienbroeker C, Tackenberg B, Limmroth V, Wildemann B, Haas J, Klotz L, Wiendl H, Ruck T, Meuth SG.

J Neurol. 2019 Jan;266(1):165-173. doi: 10.1007/s00415-018-9117-z. Epub 2018 Nov 16.

PMID:
30446966
28.

Specific T-cell activation in peripheral blood and cerebrospinal fluid in central disorders of hypersomnolence.

Lippert J, Young P, Gross C, Meuth SG, Dräger B, Schirmacher A, Heidbreder A.

Sleep. 2019 Feb 1;42(2). doi: 10.1093/sleep/zsy223.

PMID:
30445542
29.

Vitiligo after alemtuzumab treatment: Secondary autoimmunity is not all about B cells.

Ruck T, Pfeuffer S, Schulte-Mecklenbeck A, Gross CC, Lindner M, Metze D, Ehrchen J, Sondermann W, Pul R, Kleinschnitz C, Wiendl H, Meuth SG, Klotz L.

Neurology. 2018 Dec 11;91(24):e2233-e2237. doi: 10.1212/WNL.0000000000006648. Epub 2018 Nov 7.

30.

Apraxia screening predicts Alzheimer pathology in frontotemporal dementia.

Pawlowski M, Joksch V, Wiendl H, Meuth SG, Duning T, Johnen A.

J Neurol Neurosurg Psychiatry. 2019 May;90(5):562-569. doi: 10.1136/jnnp-2018-318470. Epub 2018 Oct 10.

PMID:
30305323
31.

Changes in cell differentiation and proliferation lead to production of abzymes in EAE mice treated with DNA-Histone complexes.

Aulova KS, Toporkova LB, Lopatnikova JA, Alshevskaya AA, Sedykh SE, Buneva VN, Budde T, Meuth SG, Popova NA, Orlovskaya IA, Nevinsky GA.

J Cell Mol Med. 2018 Dec;22(12):5816-5832. doi: 10.1111/jcmm.13850. Epub 2018 Sep 28.

32.

In Vitro Analyses of Novel HCN4 Gene Mutations.

Möller M, Silbernagel N, Wrobel E, Stallmayer B, Amedonu E, Rinné S, Peischard S, Meuth SG, Wünsch B, Strutz-Seebohm N, Decher N, Schulze-Bahr E, Seebohm G.

Cell Physiol Biochem. 2018;49(3):1197-1207. doi: 10.1159/000493301. Epub 2018 Sep 7.

33.

Human T cells in silico: Modelling dynamic intracellular calcium and its influence on cellular electrophysiology.

Eichinger P, Herrmann AM, Ruck T, Herty M, Gola L, Kovac S, Budde T, Meuth SG, Hundehege P.

J Immunol Methods. 2018 Oct;461:78-84. doi: 10.1016/j.jim.2018.06.020. Epub 2018 Jul 3.

PMID:
30158076
34.

Primary B Cell Lymphoma of the CNS Mimicking Anti-LGI1 Limbic Encephalitis.

Thomas C, Lehrich C, Gross CC, Wiendl H, Meuth SG, Melzer N.

Front Neurol. 2018 Aug 10;9:658. doi: 10.3389/fneur.2018.00658. eCollection 2018.

35.

The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review.

Göbel K, Eichler S, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG.

Front Immunol. 2018 Jul 26;9:1731. doi: 10.3389/fimmu.2018.01731. eCollection 2018.

36.

Discriminative power of intra-retinal layers in early multiple sclerosis using 3D OCT imaging.

Seitz CB, Droby A, Zaubitzer L, Krämer J, Paradis M, Klotz L, Wiendl H, Groppa S, Meuth SG, Zipp F, Fleischer V.

J Neurol. 2018 Oct;265(10):2284-2294. doi: 10.1007/s00415-018-8988-3. Epub 2018 Aug 2.

PMID:
30073502
37.

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor Study.

Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L.

Front Immunol. 2018 Jul 9;9:1560. doi: 10.3389/fimmu.2018.01560. eCollection 2018.

38.

Impairment of frequency-specific responses associated with altered electrical activity patterns in auditory thalamus following focal and general demyelination.

Narayanan V, Cerina M, Göbel K, Meuth P, Herrmann AM, Fernandez-Orth J, Stangel M, Gudi V, Skripuletz T, Daldrup T, Lesting J, Schiffler P, Wiendl H, Seidenbecher T, Meuth SG, Budde T, Pape HC.

Exp Neurol. 2018 Nov;309:54-66. doi: 10.1016/j.expneurol.2018.07.010. Epub 2018 Jul 23.

PMID:
30048715
39.

Primary angiitis of the central nervous system: diagnosis and treatment.

Beuker C, Schmidt A, Strunk D, Sporns PB, Wiendl H, Meuth SG, Minnerup J.

Ther Adv Neurol Disord. 2018 Jul 9;11:1756286418785071. doi: 10.1177/1756286418785071. eCollection 2018. Review.

40.

Apraxia profiles-A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease.

Johnen A, Reul S, Wiendl H, Meuth SG, Duning T.

Alzheimers Dement (Amst). 2018 May 16;10:363-371. doi: 10.1016/j.dadm.2018.04.002. eCollection 2018.

41.

Onconeural antigen spreading in paraneoplastic neurological disease due to small cell lung cancer.

Dik A, Strippel C, Mönig C, Golombeck KS, Schulte-Mecklenbeck A, Wiendl H, Meuth SG, Johnen A, Gross CC, Melzer N.

Oxf Med Case Reports. 2018 Jul 9;2018(7):omy034. doi: 10.1093/omcr/omy034. eCollection 2018 Jul.

42.

Immune cell profiling in the cerebrospinal fluid of patients with primary angiitis of the central nervous system reflects the heterogeneity of the disease.

Strunk D, Schulte-Mecklenbeck A, Golombeck KS, Meyer Zu Hörste G, Melzer N, Beuker C, Schmidt A, Wiendl H, Meuth SG, Gross CC, Minnerup J.

J Neuroimmunol. 2018 Aug 15;321:109-116. doi: 10.1016/j.jneuroim.2018.06.004. Epub 2018 Jun 7.

PMID:
29957380
43.

Amygdala enlargement and emotional responses in (autoimmune) temporal lobe epilepsy.

Holtmann O, Schlossmacher I, Moenig C, Johnen A, Rutter LM, Tenberge JG, Schiffler P, Everding J, Golombeck KS, Strippel C, Dik A, Schwindt W, Wiendl H, Meuth SG, Bruchmann M, Melzer N, Straube T.

Sci Rep. 2018 Jun 22;8(1):9561. doi: 10.1038/s41598-018-27914-z.

44.

Cerebrospinal Fluid Concentrations of Neuronal Proteins Are Reduced in Primary Angiitis of the Central Nervous System.

Ruland T, Wolbert J, Gottschalk MG, König S, Schulte-Mecklenbeck A, Minnerup J, Meuth SG, Groß CC, Wiendl H, Meyer Zu Hörste G.

Front Neurol. 2018 Jun 5;9:407. doi: 10.3389/fneur.2018.00407. eCollection 2018.

45.

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation.

Thomas C, Zühlsdorf A, Hörtnagel K, Mulahasanovic L, Grauer OM, Kümpers P, Wiendl H, Meuth SG.

Front Neurol. 2018 May 25;9:383. doi: 10.3389/fneur.2018.00383. eCollection 2018.

46.

Reliability and main findings of the flexible endoscopic evaluation of swallowing-Tensilon test in patients with myasthenia gravis and dysphagia.

Im S, Suntrup-Krueger S, Colbow S, Sauer S, Claus I, Meuth SG, Dziewas R, Warnecke T.

Eur J Neurol. 2018 Oct;25(10):1235-1242. doi: 10.1111/ene.13688. Epub 2018 Jun 22.

PMID:
29802670
47.

Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis.

Sauter RJ, Sauter M, Reis ES, Emschermann FN, Nording H, Ebenhöch S, Kraft P, Münzer P, Mauler M, Rheinlaender J, Madlung J, Edlich F, Schäffer TE, Meuth SG, Dürschmied D, Geisler T, Borst O, Gawaz M, Kleinschnitz C, Lambris JD, Langer HF.

Circulation. 2018 Oct 16;138(16):1720-1735. doi: 10.1161/CIRCULATIONAHA.118.034600. Erratum in: Circulation. 2019 Jan 15;139(3):e8.

PMID:
29802205
48.

Immunotherapy of experimental and human stroke with agents approved for multiple sclerosis: a systematic review.

Dreikorn M, Milacic Z, Pavlovic V, Meuth SG, Kleinschnitz C, Kraft P.

Ther Adv Neurol Disord. 2018 Apr 20;11:1756286418770626. doi: 10.1177/1756286418770626. eCollection 2018. Review.

49.

Protective potential of dimethyl fumarate in a mouse model of thalamocortical demyelination.

Cerina M, Narayanan V, Delank A, Meuth P, Graebenitz S, Göbel K, Herrmann AM, Albrecht S, Daldrup T, Seidenbecher T, Gorji A, Kuhlmann T, Wiendl H, Kleinschnitz C, Speckmann EJ, Pape HC, Meuth SG, Budde T.

Brain Struct Funct. 2018 Sep;223(7):3091-3106. doi: 10.1007/s00429-018-1680-7. Epub 2018 May 9.

50.

The Use of Digital and Remote Communication Technologies as a Tool for Multiple Sclerosis Management: Narrative Review.

Marziniak M, Brichetto G, Feys P, Meyding-Lamadé U, Vernon K, Meuth SG.

JMIR Rehabil Assist Technol. 2018 Apr 24;5(1):e5. doi: 10.2196/rehab.7805.

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