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Items: 1 to 50 of 340

1.

MS optic neuritis-induced long-term structural changes within the visual pathway.

Pawlitzki M, Horbrügger M, Loewe K, Kaufmann J, Opfer R, Wagner M, Al-Nosairy KO, Meuth SG, Hoffmann MB, Schippling S.

Neurol Neuroimmunol Neuroinflamm. 2020 Jan 22;7(2). pii: e665. doi: 10.1212/NXI.0000000000000665. Print 2020 Mar 5.

2.

Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study.

Heitmann H, Haller B, Tiemann L, Mühlau M, Berthele A, Tölle TR, Salmen A, Ambrosius B, Bayas A, Asseyer S, Hartung HP, Heesen C, Stangel M, Wildemann B, Haars S, Groppa S, Luessi F, Kümpfel T, Nischwitz S, Meuth SG, Klotz L, Linker RA, Zettl UK, Ziemann U, Tumani H, Tackenberg B, Zipp F, Wiendl H, Gold R, Hemmer B, Ploner M.

Pain. 2020 Apr;161(4):787-796. doi: 10.1097/j.pain.0000000000001767.

PMID:
32197038
3.

Generation of a Model to Predict Differentiation and Migration of Lymphocyte Subsets under Homeostatic and CNS Autoinflammatory Conditions.

Gross CC, Pawlitzki M, Schulte-Mecklenbeck A, Rolfes L, Ruck T, Hundehege P, Wiendl H, Herty M, Meuth SG.

Int J Mol Sci. 2020 Mar 17;21(6). pii: E2046. doi: 10.3390/ijms21062046.

4.

Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events.

Skryabin BV, Kummerfeld DM, Gubar L, Seeger B, Kaiser H, Stegemann A, Roth J, Meuth SG, Pavenstädt H, Sherwood J, Pap T, Wedlich-Söldner R, Sunderkötter C, Schwartz YB, Brosius J, Rozhdestvensky TS.

Sci Adv. 2020 Feb 12;6(7):eaax2941. doi: 10.1126/sciadv.aax2941. eCollection 2020 Feb.

5.

Tetrahydrocannabinol and cannabidiol oromucosal spray in resistant multiple sclerosis spasticity: consistency of response across subgroups from the SAVANT randomized clinical trial.

Meuth SG, Henze T, Essner U, Trompke C, Vila Silván C.

Int J Neurosci. 2020 Mar 1:1-7. doi: 10.1080/00207454.2020.1730832. [Epub ahead of print]

PMID:
32065006
6.

MOG encephalomyelitis: distinct clinical, MRI and CSF features in patients with longitudinal extensive transverse myelitis as first clinical presentation.

Loos J, Pfeuffer S, Pape K, Ruck T, Luessi F, Spreer A, Zipp F, Meuth SG, Bittner S.

J Neurol. 2020 Feb 13. doi: 10.1007/s00415-020-09755-x. [Epub ahead of print]

PMID:
32055995
7.

Gray matter integrity predicts white matter network reorganization in multiple sclerosis.

Radetz A, Koirala N, Krämer J, Johnen A, Fleischer V, Gonzalez-Escamilla G, Cerina M, Muthuraman M, Meuth SG, Groppa S.

Hum Brain Mapp. 2020 Mar;41(4):917-927. doi: 10.1002/hbm.24849. Epub 2019 Nov 5.

PMID:
32026599
8.

Covarying patterns of white matter lesions and cortical atrophy predict progression in early MS.

Muthuraman M, Fleischer V, Kroth J, Ciolac D, Radetz A, Koirala N, Gonzalez-Escamilla G, Wiendl H, Meuth SG, Zipp F, Groppa S.

Neurol Neuroimmunol Neuroinflamm. 2020 Feb 5;7(3). pii: e681. doi: 10.1212/NXI.0000000000000681. Print 2020 May 4.

9.

Continuous reorganization of cortical information flow in multiple sclerosis: A longitudinal fMRI effective connectivity study.

Fleischer V, Muthuraman M, Anwar AR, Gonzalez-Escamilla G, Radetz A, Gracien RM, Bittner S, Luessi F, Meuth SG, Zipp F, Groppa S.

Sci Rep. 2020 Jan 21;10(1):806. doi: 10.1038/s41598-020-57895-x.

10.

Initial experience with [18F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system.

Backhaus P, Roll W, Beuker C, Zinnhardt B, Seifert R, Wenning C, Eisenblätter M, Thomas C, Schmidt-Pogoda A, Strunk D, Wagner S, Faust A, Tüttelmann F, Röpke A, Jacobs AH, Stummer W, Wiendl H, Meuth SG, Schäfers M, Grauer O, Minnerup J.

Eur J Nucl Med Mol Imaging. 2020 Jan 20. doi: 10.1007/s00259-019-04662-4. [Epub ahead of print]

PMID:
31960097
11.

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis.

Schafflick D, Xu CA, Hartlehnert M, Cole M, Schulte-Mecklenbeck A, Lautwein T, Wolbert J, Heming M, Meuth SG, Kuhlmann T, Gross CC, Wiendl H, Yosef N, Meyer Zu Horste G.

Nat Commun. 2020 Jan 14;11(1):247. doi: 10.1038/s41467-019-14118-w.

12.

Production of Abzymes in Th, CBA, and C57BL/6 Mice before and after MOG Treatment: Comparing Changes in Cell Differentiation and Proliferation.

Aulova KS, Urusov AE, Toporkova LB, Sedykh SE, Shevchenko YA, Tereshchenko VP, Sennikov SV, Budde T, Meuth SG, Popova NA, Orlovskaya IA, Nevinsky GA.

Biomolecules. 2019 Dec 28;10(1). pii: E53. doi: 10.3390/biom10010053.

13.

An enigmatic case of cortical anopsia: Antemortem diagnosis of a 14-3-3 negative Heidenhain-variant MM1-sCJD.

Obergassel J, Lohmann L, Meuth SG, Wiendl H, Grauer O, Nelke C.

Prion. 2020 Dec;14(1):24-28. doi: 10.1080/19336896.2019.1706703.

14.

Comparing Plasma Exchange to Escalated Methyl Prednisolone in Refractory Multiple Sclerosis Relapses.

Pfeuffer S, Rolfes L, Bormann E, Sauerland C, Ruck T, Schilling M, Melzer N, Brand M, Pul R, Kleinschnitz C, Wiendl H, Meuth SG.

J Clin Med. 2019 Dec 22;9(1). pii: E35. doi: 10.3390/jcm9010035.

15.

Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration.

Speicher AM, Wiendl H, Meuth SG, Pawlowski M.

Mol Neurodegener. 2019 Dec 19;14(1):46. doi: 10.1186/s13024-019-0347-z. Review.

16.

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.

Gross CC, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher AR, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud DA, Loussouarn D, Parratt J, Barnett M, Buckland ME, Hardy TA, Reddel SW, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth SG, Martin-Blondel G, Wiendl H, Liblau R.

Nat Commun. 2019 Dec 18;10(1):5779. doi: 10.1038/s41467-019-13593-5.

17.

Alemtuzumab therapy changes immunoglobulin levels in peripheral blood and CSF.

Möhn N, Pfeuffer S, Ruck T, Gross CC, Skripuletz T, Klotz L, Wiendl H, Stangel M, Meuth SG.

Neurol Neuroimmunol Neuroinflamm. 2019 Dec 11;7(2). pii: e654. doi: 10.1212/NXI.0000000000000654. Print 2020 Mar.

18.

Serial position effects rapidly distinguish Alzheimer's from frontotemporal dementia.

Kloth N, Lemke J, Wiendl H, Meuth SG, Duning T, Johnen A.

J Neurol. 2020 Apr;267(4):975-983. doi: 10.1007/s00415-019-09662-w. Epub 2019 Dec 5.

PMID:
31807915
19.

Fulminant MS Reactivation Following Combined Fingolimod Cessation and Yellow Fever Vaccination.

Rolfes L, Pawlitzki M, Pfeuffer S, Thomas C, Schmidt-Chanasit J, Gross CC, Schulte-Mecklenbeck A, Wiendl H, Meuth SG, M Grauer O, Ruck T.

Int J Mol Sci. 2019 Nov 28;20(23). pii: E5985. doi: 10.3390/ijms20235985.

20.

Why Most Acute Stroke Studies Are Positive in Animals but Not in Patients: A Systematic Comparison of Preclinical, Early Phase, and Phase 3 Clinical Trials of Neuroprotective Agents.

Schmidt-Pogoda A, Bonberg N, Koecke MHM, Strecker JK, Wellmann J, Bruckmann NM, Beuker C, Schäbitz WR, Meuth SG, Wiendl H, Minnerup H, Minnerup J.

Ann Neurol. 2020 Jan;87(1):40-51. doi: 10.1002/ana.25643. Epub 2019 Nov 26.

PMID:
31714631
21.

[Frequency and risk factors associated with post-stroke dementia-an observational study on stroke patients without premorbid cognitive impairment].

Johnen A, Räthe S, Lohmann H, Philipp K, Minnerup J, Wiendl H, Meuth SG, Duning T.

Nervenarzt. 2020 Feb;91(2):131-140. doi: 10.1007/s00115-019-00830-x. German.

PMID:
31712835
22.

A case of idiopathic multicentric Castleman disease in an alemtuzumab-treated patient with MS.

Rolfes L, Pfeuffer S, Ruck T, Windhagen S, Oschlies I, Pavenstädt HJ, Angenendt L, Wiendl H, Krämer J, Meuth SG.

Neurol Neuroimmunol Neuroinflamm. 2019 Nov 8;7(1). pii: e638. doi: 10.1212/NXI.0000000000000638. Print 2020 Jan. No abstract available. Erratum in: Neurol Neuroimmunol Neuroinflamm. 2019 Dec 5;7(1):.

23.

Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis.

Keller CW, Ruck T, McHugh D, Pfeuffer S, Gross CC, Korsukewitz C, Melzer N, Klotz L, Meuth SG, Münz C, Nimmerjahn F, Wiendl H, Lünemann JD.

Ann Clin Transl Neurol. 2019 Dec;6(12):2586-2594. doi: 10.1002/acn3.50935. Epub 2019 Nov 4.

24.

Skeletal muscle as potential central link between sarcopenia and immune senescence.

Nelke C, Dziewas R, Minnerup J, Meuth SG, Ruck T.

EBioMedicine. 2019 Nov;49:381-388. doi: 10.1016/j.ebiom.2019.10.034. Epub 2019 Oct 26. Review.

25.

β1-Integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells.

Birkner K, Wasser B, Ruck T, Thalman C, Luchtman D, Pape K, Schmaul S, Bitar L, Krämer-Albers EM, Stroh A, Meuth SG, Zipp F, Bittner S.

J Clin Invest. 2020 Feb 3;130(2):715-732. doi: 10.1172/JCI126381.

26.

Resolving the cognitive clinico-radiological paradox - Microstructural degeneration of fronto-striatal-thalamic loops in early active multiple sclerosis.

Johnen A, Schiffler P, Landmeyer NC, Tenberge JG, Riepl E, Wiendl H, Krämer J, Meuth SG.

Cortex. 2019 Dec;121:239-252. doi: 10.1016/j.cortex.2019.08.022. Epub 2019 Sep 26.

PMID:
31654896
27.

Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.

Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Röth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M.

Nat Commun. 2019 Oct 25;10(1):4877. doi: 10.1038/s41467-019-12776-4.

28.

EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases.

von Martial S, Brix TJ, Klotz L, Neuhaus P, Berger K, Warnke C, Meuth SG, Wiendl H, Dugas M.

PLoS One. 2019 Oct 15;14(10):e0223886. doi: 10.1371/journal.pone.0223886. eCollection 2019.

29.

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?

Pawlitzki M, Schneider-Hohendorf T, Rolfes L, Meuth SG, Wiendl H, Schwab N, Grauer OM.

Neurol Neuroimmunol Neuroinflamm. 2019 Oct 9;6(6):e627. doi: 10.1212/NXI.0000000000000627. Print 2019 Nov. No abstract available.

30.

Therapeutic Apheresis in Acute Relapsing Multiple Sclerosis: Current Evidence and Unmet Needs-A Systematic Review.

Rolfes L, Pfeuffer S, Ruck T, Melzer N, Pawlitzki M, Heming M, Brand M, Wiendl H, Meuth SG.

J Clin Med. 2019 Oct 4;8(10). pii: E1623. doi: 10.3390/jcm8101623. Review.

31.

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke.

Stegner D, Hofmann S, Schuhmann MK, Kraft P, Herrmann AM, Popp S, Höhn M, Popp M, Klaus V, Post A, Kleinschnitz C, Braun A, Meuth SG, Lesch KP, Stoll G, Kraft R, Nieswandt B.

Stroke. 2019 Nov;50(11):3238-3245. doi: 10.1161/STROKEAHA.119.025357. Epub 2019 Sep 25.

PMID:
31551038
32.

Early effective treatment may protect from cognitive decline in paediatric multiple sclerosis.

Johnen A, Elpers C, Riepl E, Landmeyer NC, Krämer J, Polzer P, Lohmann H, Omran H, Wiendl H, Göbel K, Meuth SG.

Eur J Paediatr Neurol. 2019 Nov;23(6):783-791. doi: 10.1016/j.ejpn.2019.08.007. Epub 2019 Sep 5.

PMID:
31540711
33.

Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals.

Schwab N, Schneider-Hohendorf T, Pignolet B, Bucciarelli F, Scandella L, Ciron J, Biotti D, Lebrun-Frenay C, Mathey G, Clavelou P, Pelletier J, Ostkamp P, Meinl I, Windhagen S, Klotz L, Gross CC, Meuth SG, Deisenhammer F, Brassat D, Wiendl H; Best-MS Study Group.

Neurology. 2019 Sep 17;93(12):550-554. doi: 10.1212/WNL.0000000000008135. Epub 2019 Aug 22. No abstract available.

PMID:
31439633
34.

Selective Brain Network and Cellular Responses Upon Dimethyl Fumarate Immunomodulation in Multiple Sclerosis.

Ciolac D, Luessi F, Gonzalez-Escamilla G, Koirala N, Riedel C, Fleischer V, Bittner S, Krämer J, Meuth SG, Muthuraman M, Groppa S.

Front Immunol. 2019 Jul 30;10:1779. doi: 10.3389/fimmu.2019.01779. eCollection 2019.

35.

Sequestosome-1 (p62) expression reveals chaperone-assisted selective autophagy in immune-mediated necrotizing myopathies.

Fischer N, Preuße C, Radke J, Pehl D, Allenbach Y, Schneider U, Feist E, von Casteleyn V, Hahn K, Ruck T, Meuth SG, Goebel HH, Graf R, Mammen A, Benveniste O, Stenzel W.

Brain Pathol. 2020 Mar;30(2):261-271. doi: 10.1111/bpa.12772. Epub 2019 Aug 27.

PMID:
31376301
36.

Imaging in mice and men: Pathophysiological insights into multiple sclerosis from conventional and advanced MRI techniques.

Krämer J, Brück W, Zipp F, Cerina M, Groppa S, Meuth SG.

Prog Neurobiol. 2019 Nov;182:101663. doi: 10.1016/j.pneurobio.2019.101663. Epub 2019 Jul 30. Review.

PMID:
31374243
37.

Pretreatment anti-thyroid autoantibodies indicate increased risk for thyroid autoimmunity secondary to alemtuzumab: A prospective cohort study.

Ruck T, Schulte-Mecklenbeck A, Pfeuffer S, Heming M, Klotz L, Windhagen S, Kleinschnitz C, Gross CC, Wiendl H, Meuth SG.

EBioMedicine. 2019 Aug;46:381-386. doi: 10.1016/j.ebiom.2019.07.062. Epub 2019 Jul 29.

38.

Brain fibrinogen deposition plays a key role in MS pathophysiology - No.

Göbel K, Meuth SG.

Mult Scler. 2019 Oct;25(11):1436-1437. doi: 10.1177/1352458518820240. Epub 2019 Jul 18. No abstract available.

PMID:
31315524
39.

[Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany].

Bittner S, Engel S, Lange C, Weber MS, Haghikia A, Luessi F, Korn T, Klotz L, Bayas A, Paul F, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Trebst C, Warnke C, Linker R, Kerschensteiner M, Zettl U, Tumani H, Brück W, Meuth SG, Kümpfel T, Hemmer B, Wiendl H, Gold R, Zipp F.

Nervenarzt. 2019 Dec;90(12):1245-1253. doi: 10.1007/s00115-019-0760-0. Review. German.

PMID:
31297574
40.

The next-generation sphingosine-1 receptor modulator BAF312 (siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis.

Hundehege P, Cerina M, Eichler S, Thomas C, Herrmann AM, Göbel K, Müntefering T, Fernandez-Orth J, Bock S, Narayanan V, Budde T, Speckmann EJ, Wiendl H, Schubart A, Ruck T, Meuth SG.

Neural Regen Res. 2019 Nov;14(11):1950-1960. doi: 10.4103/1673-5374.259622.

41.

Seizure-induced shoulder dislocations - Case series and review of the literature.

Langenbruch L, Rickert C, Gosheger G, Schorn D, Schliemann B, Brix T, Elger CE, Meuth SG, Kovac S.

Seizure. 2019 Aug;70:38-42. doi: 10.1016/j.seizure.2019.06.025. Epub 2019 Jun 20. Review.

PMID:
31252362
42.

Biomarkers in Vasculitides of the Nervous System.

Strunk D, Schmidt-Pogoda A, Beuker C, Milles LS, Korsukewitz C, Meuth SG, Minnerup J.

Front Neurol. 2019 Jun 6;10:591. doi: 10.3389/fneur.2019.00591. eCollection 2019. Review.

43.

Alemtuzumab in Multiple Sclerosis: Short- and Long-Term Effects of Immunodepletion on the Peripheral Treg Compartment.

Haas J, Würthwein C, Korporal-Kuhnke M, Viehoever A, Jarius S, Ruck T, Pfeuffer S, Meuth SG, Wildemann B.

Front Immunol. 2019 Jun 4;10:1204. doi: 10.3389/fimmu.2019.01204. eCollection 2019.

44.

CSF Neurofilament light chain level predicts axonal damage in cerebral vasculitis.

Pawlitzki M, Butryn M, Kirchner F, Färber J, Beuing O, Minnerup J, Meuth SG, Neumann J.

Ann Clin Transl Neurol. 2019 Jun 3;6(6):1134-1137. doi: 10.1002/acn3.790. eCollection 2019 Jun.

45.

An update on Peginterferon beta-1a Management in Multiple Sclerosis: results from an interdisciplinary Board of German and Austrian Neurologists and dermatologists.

Kolb-Mäurer A, Sunderkötter C, Kukowski B, Meuth SG; members of an expert meeting.

BMC Neurol. 2019 Jun 15;19(1):130. doi: 10.1186/s12883-019-1354-y.

46.

Seizures and epilepsy in multiple sclerosis: epidemiology and prognosis in a large tertiary referral center.

Langenbruch L, Krämer J, Güler S, Möddel G, Geßner S, Melzer N, Elger CE, Wiendl H, Budde T, Meuth SG, Kovac S.

J Neurol. 2019 Jul;266(7):1789-1795. doi: 10.1007/s00415-019-09332-x. Epub 2019 May 8.

PMID:
31069528
47.

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.

Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H.

Sci Transl Med. 2019 May 1;11(490). pii: eaao5563. doi: 10.1126/scitranslmed.aao5563.

PMID:
31043571
48.

Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis.

Fleischer V, Koirala N, Droby A, Gracien RM, Deichmann R, Ziemann U, Meuth SG, Muthuraman M, Zipp F, Groppa S.

Ther Adv Neurol Disord. 2019 Apr 24;12:1756286419838673. doi: 10.1177/1756286419838673. eCollection 2019.

49.

Substance P Saliva Reduction Predicts Pharyngeal Dysphagia in Parkinson's Disease.

Schröder JB, Marian T, Claus I, Muhle P, Pawlowski M, Wiendl H, Suntrup-Krueger S, Meuth SG, Dziewas R, Ruck T, Warnecke T.

Front Neurol. 2019 Apr 16;10:386. doi: 10.3389/fneur.2019.00386. eCollection 2019.

50.

Immune Cell Profiling of the Cerebrospinal Fluid Provides Pathogenetic Insights Into Inflammatory Neuropathies.

Heming M, Schulte-Mecklenbeck A, Brix T, Wolbert J, Ruland T, Klotz L, Meuth SG, Gross CC, Wiendl H, Meyer Zu Hörste G.

Front Immunol. 2019 Mar 21;10:515. doi: 10.3389/fimmu.2019.00515. eCollection 2019.

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