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Items: 1 to 50 of 323

1.

Serial position effects rapidly distinguish Alzheimer's from frontotemporal dementia.

Kloth N, Lemke J, Wiendl H, Meuth SG, Duning T, Johnen A.

J Neurol. 2019 Dec 5. doi: 10.1007/s00415-019-09662-w. [Epub ahead of print]

PMID:
31807915
2.

Fulminant MS Reactivation Following Combined Fingolimod Cessation and Yellow Fever Vaccination.

Rolfes L, Pawlitzki M, Pfeuffer S, Thomas C, Schmidt-Chanasit J, Gross CC, Schulte-Mecklenbeck A, Wiendl H, Meuth SG, M Grauer O, Ruck T.

Int J Mol Sci. 2019 Nov 28;20(23). pii: E5985. doi: 10.3390/ijms20235985.

3.

Why Most Acute Stroke Studies Are Positive in Animals but Not in Patients: A Systematic Comparison of Preclinical, Early Phase, and Phase 3 Clinical Trials of Neuroprotective Agents.

Schmidt-Pogoda A, Bonberg N, Koecke MHM, Strecker JK, Wellmann J, Bruckmann NM, Beuker C, Schäbitz WR, Meuth SG, Wiendl H, Minnerup H, Minnerup J.

Ann Neurol. 2019 Nov 12. doi: 10.1002/ana.25643. [Epub ahead of print]

PMID:
31714631
4.

[Frequency and risk factors associated with post-stroke dementia-an observational study on stroke patients without premorbid cognitive impairment].

Johnen A, Räthe S, Lohmann H, Philipp K, Minnerup J, Wiendl H, Meuth SG, Duning T.

Nervenarzt. 2019 Nov 11. doi: 10.1007/s00115-019-00830-x. [Epub ahead of print] German.

PMID:
31712835
5.

A case of idiopathic multicentric Castleman disease in an alemtuzumab-treated patient with MS.

Rolfes L, Pfeuffer S, Ruck T, Windhagen S, Oschlies I, Pavenstädt HJ, Angenendt L, Wiendl H, Krämer J, Meuth SG.

Neurol Neuroimmunol Neuroinflamm. 2019 Nov 8;7(1). pii: e638. doi: 10.1212/NXI.0000000000000638. Print 2020 Jan. No abstract available. Erratum in: Neurol Neuroimmunol Neuroinflamm. 2019 Dec 5;7(1):.

6.

Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis.

Keller CW, Ruck T, McHugh D, Pfeuffer S, Gross CC, Korsukewitz C, Melzer N, Klotz L, Meuth SG, Münz C, Nimmerjahn F, Wiendl H, Lünemann JD.

Ann Clin Transl Neurol. 2019 Nov 4. doi: 10.1002/acn3.50935. [Epub ahead of print]

7.

Skeletal muscle as potential central link between sarcopenia and immune senescence.

Nelke C, Dziewas R, Minnerup J, Meuth SG, Ruck T.

EBioMedicine. 2019 Nov;49:381-388. doi: 10.1016/j.ebiom.2019.10.034. Epub 2019 Oct 26. Review.

8.

β1-integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells.

Birkner K, Wasser B, Ruck T, Thalman C, Luchtman D, Pape K, Schmaul S, Bitar L, Krämer-Albers EM, Stroh A, Meuth SG, Zipp F, Bittner S.

J Clin Invest. 2019 Oct 29. pii: 126381. doi: 10.1172/JCI126381. [Epub ahead of print]

9.

Resolving the cognitive clinico-radiological paradox - Microstructural degeneration of fronto-striatal-thalamic loops in early active multiple sclerosis.

Johnen A, Schiffler P, Landmeyer NC, Tenberge JG, Riepl E, Wiendl H, Krämer J, Meuth SG.

Cortex. 2019 Dec;121:239-252. doi: 10.1016/j.cortex.2019.08.022. Epub 2019 Sep 26.

PMID:
31654896
10.

Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.

Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Röth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M.

Nat Commun. 2019 Oct 25;10(1):4877. doi: 10.1038/s41467-019-12776-4.

11.

EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases.

von Martial S, Brix TJ, Klotz L, Neuhaus P, Berger K, Warnke C, Meuth SG, Wiendl H, Dugas M.

PLoS One. 2019 Oct 15;14(10):e0223886. doi: 10.1371/journal.pone.0223886. eCollection 2019.

12.

Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?

Pawlitzki M, Schneider-Hohendorf T, Rolfes L, Meuth SG, Wiendl H, Schwab N, Grauer OM.

Neurol Neuroimmunol Neuroinflamm. 2019 Oct 9;6(6):e627. doi: 10.1212/NXI.0000000000000627. Print 2019 Nov. No abstract available.

13.

Therapeutic Apheresis in Acute Relapsing Multiple Sclerosis: Current Evidence and Unmet Needs-A Systematic Review.

Rolfes L, Pfeuffer S, Ruck T, Melzer N, Pawlitzki M, Heming M, Brand M, Wiendl H, Meuth SG.

J Clin Med. 2019 Oct 4;8(10). pii: E1623. doi: 10.3390/jcm8101623. Review.

14.

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke.

Stegner D, Hofmann S, Schuhmann MK, Kraft P, Herrmann AM, Popp S, Höhn M, Popp M, Klaus V, Post A, Kleinschnitz C, Braun A, Meuth SG, Lesch KP, Stoll G, Kraft R, Nieswandt B.

Stroke. 2019 Nov;50(11):3238-3245. doi: 10.1161/STROKEAHA.119.025357. Epub 2019 Sep 25.

PMID:
31551038
15.

Early effective treatment may protect from cognitive decline in paediatric multiple sclerosis.

Johnen A, Elpers C, Riepl E, Landmeyer NC, Krämer J, Polzer P, Lohmann H, Omran H, Wiendl H, Göbel K, Meuth SG.

Eur J Paediatr Neurol. 2019 Nov;23(6):783-791. doi: 10.1016/j.ejpn.2019.08.007. Epub 2019 Sep 5.

PMID:
31540711
16.

Prospective validation of the PML risk biomarker l-selectin and influence of natalizumab extended intervals.

Schwab N, Schneider-Hohendorf T, Pignolet B, Bucciarelli F, Scandella L, Ciron J, Biotti D, Lebrun-Frenay C, Mathey G, Clavelou P, Pelletier J, Ostkamp P, Meinl I, Windhagen S, Klotz L, Gross CC, Meuth SG, Deisenhammer F, Brassat D, Wiendl H; Best-MS Study Group.

Neurology. 2019 Sep 17;93(12):550-554. doi: 10.1212/WNL.0000000000008135. Epub 2019 Aug 22. No abstract available.

PMID:
31439633
17.

Selective Brain Network and Cellular Responses Upon Dimethyl Fumarate Immunomodulation in Multiple Sclerosis.

Ciolac D, Luessi F, Gonzalez-Escamilla G, Koirala N, Riedel C, Fleischer V, Bittner S, Krämer J, Meuth SG, Muthuraman M, Groppa S.

Front Immunol. 2019 Jul 30;10:1779. doi: 10.3389/fimmu.2019.01779. eCollection 2019.

18.

Sequestosome-1 (p62) expression reveals chaperone-assisted selective autophagy in immune-mediated necrotizing myopathies.

Fischer N, Preuße C, Radke J, Pehl D, Allenbach Y, Schneider U, Feist E, von Casteleyn V, Hahn K, Ruck T, Meuth SG, Goebel HH, Graf R, Mammen A, Benveniste O, Stenzel W.

Brain Pathol. 2019 Aug 3. doi: 10.1111/bpa.12772. [Epub ahead of print]

PMID:
31376301
19.

Imaging in mice and men: Pathophysiological insights into multiple sclerosis from conventional and advanced MRI techniques.

Krämer J, Brück W, Zipp F, Cerina M, Groppa S, Meuth SG.

Prog Neurobiol. 2019 Nov;182:101663. doi: 10.1016/j.pneurobio.2019.101663. Epub 2019 Jul 30. Review.

PMID:
31374243
20.

Pretreatment anti-thyroid autoantibodies indicate increased risk for thyroid autoimmunity secondary to alemtuzumab: A prospective cohort study.

Ruck T, Schulte-Mecklenbeck A, Pfeuffer S, Heming M, Klotz L, Windhagen S, Kleinschnitz C, Gross CC, Wiendl H, Meuth SG.

EBioMedicine. 2019 Aug;46:381-386. doi: 10.1016/j.ebiom.2019.07.062. Epub 2019 Jul 29.

21.

Brain fibrinogen deposition plays a key role in MS pathophysiology - No.

Göbel K, Meuth SG.

Mult Scler. 2019 Oct;25(11):1436-1437. doi: 10.1177/1352458518820240. Epub 2019 Jul 18. No abstract available.

PMID:
31315524
22.

[Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany].

Bittner S, Engel S, Lange C, Weber MS, Haghikia A, Luessi F, Korn T, Klotz L, Bayas A, Paul F, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Trebst C, Warnke C, Linker R, Kerschensteiner M, Zettl U, Tumani H, Brück W, Meuth SG, Kümpfel T, Hemmer B, Wiendl H, Gold R, Zipp F.

Nervenarzt. 2019 Dec;90(12):1245-1253. doi: 10.1007/s00115-019-0760-0. Review. German.

PMID:
31297574
23.

The next-generation sphingosine-1 receptor modulator BAF312 (siponimod) improves cortical network functionality in focal autoimmune encephalomyelitis.

Hundehege P, Cerina M, Eichler S, Thomas C, Herrmann AM, Göbel K, Müntefering T, Fernandez-Orth J, Bock S, Narayanan V, Budde T, Speckmann EJ, Wiendl H, Schubart A, Ruck T, Meuth SG.

Neural Regen Res. 2019 Nov;14(11):1950-1960. doi: 10.4103/1673-5374.259622.

24.

Seizure-induced shoulder dislocations - Case series and review of the literature.

Langenbruch L, Rickert C, Gosheger G, Schorn D, Schliemann B, Brix T, Elger CE, Meuth SG, Kovac S.

Seizure. 2019 Aug;70:38-42. doi: 10.1016/j.seizure.2019.06.025. Epub 2019 Jun 20.

PMID:
31252362
25.

Biomarkers in Vasculitides of the Nervous System.

Strunk D, Schmidt-Pogoda A, Beuker C, Milles LS, Korsukewitz C, Meuth SG, Minnerup J.

Front Neurol. 2019 Jun 6;10:591. doi: 10.3389/fneur.2019.00591. eCollection 2019. Review.

26.

Alemtuzumab in Multiple Sclerosis: Short- and Long-Term Effects of Immunodepletion on the Peripheral Treg Compartment.

Haas J, Würthwein C, Korporal-Kuhnke M, Viehoever A, Jarius S, Ruck T, Pfeuffer S, Meuth SG, Wildemann B.

Front Immunol. 2019 Jun 4;10:1204. doi: 10.3389/fimmu.2019.01204. eCollection 2019.

27.

CSF Neurofilament light chain level predicts axonal damage in cerebral vasculitis.

Pawlitzki M, Butryn M, Kirchner F, Färber J, Beuing O, Minnerup J, Meuth SG, Neumann J.

Ann Clin Transl Neurol. 2019 Jun 3;6(6):1134-1137. doi: 10.1002/acn3.790. eCollection 2019 Jun.

28.

An update on Peginterferon beta-1a Management in Multiple Sclerosis: results from an interdisciplinary Board of German and Austrian Neurologists and dermatologists.

Kolb-Mäurer A, Sunderkötter C, Kukowski B, Meuth SG; members of an expert meeting.

BMC Neurol. 2019 Jun 15;19(1):130. doi: 10.1186/s12883-019-1354-y.

29.

Seizures and epilepsy in multiple sclerosis: epidemiology and prognosis in a large tertiary referral center.

Langenbruch L, Krämer J, Güler S, Möddel G, Geßner S, Melzer N, Elger CE, Wiendl H, Budde T, Meuth SG, Kovac S.

J Neurol. 2019 Jul;266(7):1789-1795. doi: 10.1007/s00415-019-09332-x. Epub 2019 May 8.

PMID:
31069528
30.

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.

Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H.

Sci Transl Med. 2019 May 1;11(490). pii: eaao5563. doi: 10.1126/scitranslmed.aao5563.

PMID:
31043571
31.

Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis.

Fleischer V, Koirala N, Droby A, Gracien RM, Deichmann R, Ziemann U, Meuth SG, Muthuraman M, Zipp F, Groppa S.

Ther Adv Neurol Disord. 2019 Apr 24;12:1756286419838673. doi: 10.1177/1756286419838673. eCollection 2019.

32.

Substance P Saliva Reduction Predicts Pharyngeal Dysphagia in Parkinson's Disease.

Schröder JB, Marian T, Claus I, Muhle P, Pawlowski M, Wiendl H, Suntrup-Krueger S, Meuth SG, Dziewas R, Ruck T, Warnecke T.

Front Neurol. 2019 Apr 16;10:386. doi: 10.3389/fneur.2019.00386. eCollection 2019.

33.

Immune Cell Profiling of the Cerebrospinal Fluid Provides Pathogenetic Insights Into Inflammatory Neuropathies.

Heming M, Schulte-Mecklenbeck A, Brix T, Wolbert J, Ruland T, Klotz L, Meuth SG, Gross CC, Wiendl H, Meyer Zu Hörste G.

Front Immunol. 2019 Mar 21;10:515. doi: 10.3389/fimmu.2019.00515. eCollection 2019.

34.

Glial Activation Markers in CSF and Serum From Patients With Primary Progressive Multiple Sclerosis: Potential of Serum GFAP as Disease Severity Marker?

Abdelhak A, Hottenrott T, Morenas-Rodríguez E, Suárez-Calvet M, Zettl UK, Haass C, Meuth SG, Rauer S, Otto M, Tumani H, Huss A.

Front Neurol. 2019 Mar 26;10:280. doi: 10.3389/fneur.2019.00280. eCollection 2019.

35.

Best Practices for Long-Term Monitoring and Follow-Up of Alemtuzumab-Treated MS Patients in Real-World Clinical Settings.

Barclay K, Carruthers R, Traboulsee A, Bass AD, LaGanke C, Bertolotto A, Boster A, Celius EG, de Seze J, Cruz DD, Habek M, Lee JM, Limmroth V, Meuth SG, Oreja-Guevara C, Pagnotta P, Vos C, Ziemssen T, Baker DP, Wijmeersch BV.

Front Neurol. 2019 Mar 22;10:253. doi: 10.3389/fneur.2019.00253. eCollection 2019. Review.

36.

Neuronal ICAM-5 Plays a Neuroprotective Role in Progressive Neurodegeneration.

Birkner K, Loos J, Gollan R, Steffen F, Wasser B, Ruck T, Meuth SG, Zipp F, Bittner S.

Front Neurol. 2019 Mar 12;10:205. doi: 10.3389/fneur.2019.00205. eCollection 2019.

37.

Isolation of Primary Murine Skeletal Muscle Microvascular Endothelial Cells.

Müntefering T, Michels APE, Pfeuffer S, Meuth SG, Ruck T.

J Vis Exp. 2019 Mar 6;(145). doi: 10.3791/58901.

PMID:
30907887
38.

An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis.

Amedonu E, Brenker C, Barman S, Schreiber JA, Becker S, Peischard S, Strutz-Seebohm N, Strippel C, Dik A, Hartung HP, Budde T, Wiendl H, Strünker T, Wünsch B, Goebels N, Meuth SG, Seebohm G, Melzer N.

Front Neurol. 2019 Mar 1;10:178. doi: 10.3389/fneur.2019.00178. eCollection 2019.

39.

The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.

Zobeiri M, Chaudhary R, Blaich A, Rottmann M, Herrmann S, Meuth P, Bista P, Kanyshkova T, Lüttjohann A, Narayanan V, Hundehege P, Meuth SG, Romanelli MN, Urbano FJ, Pape HC, Budde T, Ludwig A.

Cereb Cortex. 2019 May 1;29(5):2291-2304. doi: 10.1093/cercor/bhz047.

40.

A fatal case of daclizumab-induced liver failure in a patient with MS.

Stettner M, Gross CC, Mausberg AK, Pul R, Junker A, Baba HA, Schulte-Mecklenbeck A, Wiendl H, Kleinschnitz C, Meuth SG.

Neurol Neuroimmunol Neuroinflamm. 2019 Jan 21;6(2):e539. doi: 10.1212/NXI.0000000000000539. eCollection 2019 Mar. No abstract available.

41.

Immune thrombocytopenia in alemtuzumab-treated MS patients: Incidence, detection, and management.

Cuker A, Bass AD, Nadj C, Agius MA, Steingo B, Selmaj KW, Thoits T, Guerreiro A, Van Wijmeersch B, Ziemssen T, Meuth SG, LaGanke CC, Thangavelu K, Rodriguez CE, Baker DP, Margolin DH, Jannsens A.

Mult Scler. 2019 Feb 20:1352458518816612. doi: 10.1177/1352458518816612. [Epub ahead of print]

PMID:
30785358
42.

Immunophenotyping of cerebrospinal fluid cells in ischaemic stroke.

Schulte-Mecklenbeck A, Kleffner I, Beuker C, Wirth T, Hartwig M, Schmidt-Pogoda A, Klotz L, Hansen W, Wiendl H, Meuth SG, Gross CC, Minnerup J.

Eur J Neurol. 2019 Jun;26(6):919-926. doi: 10.1111/ene.13909. Epub 2019 Feb 8.

PMID:
30659722
43.

CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration.

Pawlitzki M, Schreiber S, Bittner D, Kreipe J, Leypoldt F, Rupprecht K, Carare RO, Meuth SG, Vielhaber S, Körtvélyessy P.

Front Neurol. 2018 Dec 14;9:1037. doi: 10.3389/fneur.2018.01037. eCollection 2018.

44.

The K2P -channel TASK1 affects Oligodendroglial differentiation but not myelin restoration.

Albrecht S, Korr S, Nowack L, Narayanan V, Starost L, Stortz F, Araúzo-Bravo MJ, Meuth SG, Kuhlmann T, Hundehege P.

Glia. 2019 May;67(5):870-883. doi: 10.1002/glia.23577. Epub 2019 Jan 9.

PMID:
30623969
45.

Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease.

Schröder JB, Pawlowski M, Meyer Zu Hörste G, Gross CC, Wiendl H, Meuth SG, Ruck T, Warnecke T.

Front Neurol. 2018 Dec 18;9:1081. doi: 10.3389/fneur.2018.01081. eCollection 2018.

46.

Cell injury and receptor expression in the epileptic human amygdala.

Jafarian M, Modarres Mousavi SM, Alipour F, Aligholi H, Noorbakhsh F, Ghadipasha M, Gharehdaghi J, Kellinghaus C, Kovac S, Khaleghi Ghadiri M, Meuth SG, Speckmann EJ, Stummer W, Gorji A.

Neurobiol Dis. 2019 Apr;124:416-427. doi: 10.1016/j.nbd.2018.12.017. Epub 2018 Dec 24.

PMID:
30590180
47.

Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release.

Göbel K, Asaridou CM, Merker M, Eichler S, Herrmann AM, Geuß E, Ruck T, Schüngel L, Groeneweg L, Narayanan V, Schneider-Hohendorf T, Gross CC, Wiendl H, Kehrel BE, Kleinschnitz C, Meuth SG.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):271-276. doi: 10.1073/pnas.1810020116. Epub 2018 Dec 17.

48.

TPP2 mutation associated with sterile brain inflammation mimicking MS.

Reinthaler EM, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill CM, Hoffjan S, Epplen JT, Zettl UK, Hecker M, Deutschländer A, Meuth SG, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick AD, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A.

Neurol Genet. 2018 Nov 13;4(6):e285. doi: 10.1212/NXG.0000000000000285. eCollection 2018 Dec.

49.

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).

Johnen A, Bürkner PC, Landmeyer NC, Ambrosius B, Calabrese P, Motte J, Hessler N, Antony G, König IR, Klotz L, Hoshi MM, Aly L, Groppa S, Luessi F, Paul F, Tackenberg B, Bergh FT, Kümpfel T, Tumani H, Stangel M, Weber F, Bayas A, Wildemann B, Heesen C, Zettl UK, Zipp F, Hemmer B, Meuth SG, Gold R, Wiendl H, Salmen A; German Competence Network Multiple Sclerosis (KKNMS).

J Neurol. 2019 Feb;266(2):386-397. doi: 10.1007/s00415-018-9142-y. Epub 2018 Dec 4.

50.

Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis.

Hundehege P, Fernandez-Orth J, Römer P, Ruck T, Müntefering T, Eichler S, Cerina M, Epping L, Albrecht S, Menke AF, Birkner K, Göbel K, Budde T, Zipp F, Wiendl H, Gorji A, Bittner S, Meuth SG.

Neurosignals. 2018;26(1):77-93. doi: 10.1159/000495425. Epub 2018 Nov 27. Review.

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