Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 188

1.

Second M3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium.

Kistemaker LEM, Elzinga CRS, Tautermann CS, Pieper MP, Seeliger D, Alikhil S, Schmidt M, Meurs H, Gosens R.

Br J Pharmacol. 2019 May 11. doi: 10.1111/bph.14707. [Epub ahead of print]

PMID:
31077341
2.

Recent Patents in Allergy/Immunology: Use of arginase inhibitors in the treatment of asthma and allergic rhinitis.

Meurs H, Zaagsma J, Maarsingh H, van Duin M.

Allergy. 2019 Jun;74(6):1206-1208. doi: 10.1111/all.13770. Epub 2019 Apr 10. No abstract available.

3.

Small airway hyperresponsiveness in COPD: relationship between structure and function in lung slices.

Maarsingh H, Bidan CM, Brook BS, Zuidhof AB, Elzinga CRS, Smit M, Oldenburger A, Gosens R, Timens W, Meurs H.

Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L537-L546. doi: 10.1152/ajplung.00325.2018. Epub 2019 Jan 10.

4.

Correction: TERT promoter mutation in adult granulosa cell tumor of the ovary.

Pilsworth JA, Cochrane DR, Xia Z, Aubert G, Färkkilä AEM, Horlings HM, Yanagida S, Yang W, Lim JLP, Wang YK, Bashashati A, Keul J, Wong A, Norris K, Brucker SY, Taran FA, Krämer B, Staebler A, van Meurs H, Oliva E, Shah SP, Kommoss S, Kommoss F, Gilks CB, Baird DM, Huntsman DG.

Mod Pathol. 2019 Apr;32(4):593. doi: 10.1038/s41379-018-0085-8.

PMID:
29968850
5.

Delivery system for budesonide based on lipid-DNA.

Liu Y, Bos IST, Oenema TA, Meurs H, Maarsingh H, Hirsch AKH.

Eur J Pharm Biopharm. 2018 Sep;130:123-127. doi: 10.1016/j.ejpb.2018.06.012. Epub 2018 Jun 14.

PMID:
29908939
6.

Targeting arginase and nitric oxide metabolism in chronic airway diseases and their co-morbidities.

van den Berg MP, Meurs H, Gosens R.

Curr Opin Pharmacol. 2018 Jun;40:126-133. doi: 10.1016/j.coph.2018.04.010. Epub 2018 May 2. Review.

7.

TERT promoter mutation in adult granulosa cell tumor of the ovary.

Pilsworth JA, Cochrane DR, Xia Z, Aubert G, Färkkilä AEM, Horlings HM, Yanagida S, Yang W, Lim JLP, Wang YK, Bashashati A, Keul J, Wong A, Norris K, Brucker SY, Taran FA, Krämer B, Staebler A, van Meurs H, Oliva E, Shah SP, Kommoss S, Kommoss F, Gilks CB, Baird DM, Huntsman DG.

Mod Pathol. 2018 Jul;31(7):1107-1115. doi: 10.1038/s41379-018-0007-9. Epub 2018 Feb 15. Erratum in: Mod Pathol. 2018 Jul 3;:.

8.

Cost-effectiveness of laparoscopy as diagnostic tool before primary cytoreductive surgery in ovarian cancer.

van de Vrie R, van Meurs HS, Rutten MJ, Naaktgeboren CA, Opmeer BC, Gaarenstroom KN, van Gorp T, Ter Brugge HG, Hofhuis W, Schreuder HWR, Arts HJG, Zusterzeel PLM, Pijnenborg JMA, van Haaften M, Engelen MJA, Boss EA, Vos MC, Gerestein KG, Schutter EMJ, Kenter GG, Bossuyt PMM, Mol BW, Buist MR.

Gynecol Oncol. 2017 Sep;146(3):449-456. doi: 10.1016/j.ygyno.2017.06.019. Epub 2017 Jun 20.

PMID:
28645428
9.

Laparoscopy to Predict the Result of Primary Cytoreductive Surgery in Patients With Advanced Ovarian Cancer: A Randomized Controlled Trial.

Rutten MJ, van Meurs HS, van de Vrie R, Gaarenstroom KN, Naaktgeboren CA, van Gorp T, Ter Brugge HG, Hofhuis W, Schreuder HW, Arts HJ, Zusterzeel PL, Pijnenborg JM, van Haaften M, Fons G, Engelen MJ, Boss EA, Vos MC, Gerestein KG, Schutter EM, Opmeer BC, Spijkerboer AM, Bossuyt PM, Mol BW, Kenter GG, Buist MR.

J Clin Oncol. 2017 Feb 20;35(6):613-621. doi: 10.1200/JCO.2016.69.2962. Epub 2016 Dec 28.

PMID:
28029317
10.

Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype.

McConechy MK, Färkkilä A, Horlings HM, Talhouk A, Unkila-Kallio L, van Meurs HS, Yang W, Rozenberg N, Andersson N, Zaby K, Bryk S, Bützow R, Halfwerk JB, Hooijer GK, van de Vijver MJ, Buist MR, Kenter GG, Brucker SY, Krämer B, Staebler A, Bleeker MC, Heikinheimo M, Kommoss S, Blake Gilks C, Anttonen M, Huntsman DG.

J Natl Cancer Inst. 2016 Jun 13;108(11). pii: djw134. doi: 10.1093/jnci/djw134. Print 2016 Nov. Erratum in: J Natl Cancer Inst. 2017 Apr 1;109(4):.

11.

The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease.

Han B, Poppinga WJ, Zuo H, Zuidhof AB, Bos IS, Smit M, Vogelaar P, Krenning G, Henning RH, Maarsingh H, Halayko AJ, van Vliet B, Stienstra S, Graaf AC, Meurs H, Schmidt M.

Sci Rep. 2016 May 27;6:26928. doi: 10.1038/srep26928.

12.

TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8.

Spanjer AI, Baarsma HA, Oostenbrink LM, Jansen SR, Kuipers CC, Lindner M, Postma DS, Meurs H, Heijink IH, Gosens R, Königshoff M.

FASEB J. 2016 May;30(5):1823-35. doi: 10.1096/fj.201500129. Epub 2016 Feb 5.

PMID:
26849959
13.

Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma.

Kistemaker LE, Bos IS, Menzen MH, Maarsingh H, Meurs H, Gosens R.

Respir Res. 2016 Feb 4;17:13. doi: 10.1186/s12931-016-0327-6.

14.

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis.

Spanjer AI, Menzen MH, Dijkstra AE, van den Berge M, Boezen HM, Nickle DC, Sin DD, Bossé Y, Brandsma CA, Timens W, Postma DS, Meurs H, Heijink IH, Gosens R.

Thorax. 2016 Apr;71(4):312-22. doi: 10.1136/thoraxjnl-2015-206958. Epub 2016 Jan 21.

PMID:
26797711
15.

Airway and Extracellular Matrix Mechanics in COPD.

Bidan CM, Veldsink AC, Meurs H, Gosens R.

Front Physiol. 2015 Dec 2;6:346. doi: 10.3389/fphys.2015.00346. eCollection 2015. Review.

16.

The HysNiche trial: hysteroscopic resection of uterine caesarean scar defect (niche) in patients with abnormal bleeding, a randomised controlled trial.

Vervoort AJ, Van der Voet LF, Witmer M, Thurkow AL, Radder CM, van Kesteren PJ, Quartero HW, Kuchenbecker WK, Bongers MY, Geomini PM, de Vleeschouwer LH, van Hooff MH, van Vliet HA, Veersema S, Renes WB, van Meurs HS, Bosmans J, Oude Rengerink K, Brölmann HA, Mol BW, Huirne JA.

BMC Womens Health. 2015 Nov 12;15:103. doi: 10.1186/s12905-015-0260-8.

17.

Anti-inflammatory effects of targeted lung denervation in patients with COPD.

Kistemaker LE, Slebos DJ, Meurs H, Kerstjens HA, Gosens R.

Eur Respir J. 2015 Nov;46(5):1489-92. doi: 10.1183/13993003.00413-2015. Epub 2015 Sep 4. No abstract available.

18.

Evaluation of response to hormone therapy in patients with measurable adult granulosa cell tumors of the ovary.

van Meurs HS, van der Velden J, Buist MR, van Driel WJ, Kenter GG, van Lonkhuijzen LR.

Acta Obstet Gynecol Scand. 2015 Nov;94(11):1269-75. doi: 10.1111/aogs.12720. Epub 2015 Sep 15.

PMID:
26230362
19.

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells.

Kistemaker LE, Hiemstra PS, Bos IS, Bouwman S, van den Berge M, Hylkema MN, Meurs H, Kerstjens HA, Gosens R.

Thorax. 2015 Jul;70(7):668-76. doi: 10.1136/thoraxjnl-2014-205731. Epub 2015 May 20.

PMID:
25995156
20.

L-thyroxine promotes a proliferative airway smooth muscle phenotype in the presence of TGF-β1.

Dekkers BG, Naeimi S, Bos IS, Menzen MH, Halayko AJ, Hashjin GS, Meurs H.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 1;308(3):L301-6. doi: 10.1152/ajplung.00071.2014. Epub 2014 Dec 5.

21.

Integrins: therapeutic targets in airway hyperresponsiveness and remodelling?

Wright DB, Meurs H, Dekkers BG.

Trends Pharmacol Sci. 2014 Nov;35(11):567-74. doi: 10.1016/j.tips.2014.09.006. Epub 2014 Oct 16. Review.

PMID:
25441775
22.

Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice.

Kistemaker LE, van Os RP, Dethmers-Ausema A, Bos IS, Hylkema MN, van den Berge M, Hiemstra PS, Wess J, Meurs H, Kerstjens HA, Gosens R.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 1;308(1):L96-103. doi: 10.1152/ajplung.00259.2014. Epub 2014 Nov 7.

23.

Mechanisms of glucocorticoid action and insensitivity in airways disease.

Boardman C, Chachi L, Gavrila A, Keenan CR, Perry MM, Xia YC, Meurs H, Sharma P.

Pulm Pharmacol Ther. 2014 Dec;29(2):129-43. doi: 10.1016/j.pupt.2014.08.008. Epub 2014 Sep 9. Review.

PMID:
25218650
24.

Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.

Oldenburger A, Timens W, Bos S, Smit M, Smrcka AV, Laurent AC, Cao J, Hylkema M, Meurs H, Maarsingh H, Lezoualc'h F, Schmidt M.

FASEB J. 2014 Nov;28(11):4617-28. doi: 10.1096/fj.13-248930. Epub 2014 Aug 7.

25.

Interaction between Epac1 and miRNA-7 in airway smooth muscle cells.

Oldenburger A, van Basten B, Kooistra W, Meurs H, Maarsingh H, Krenning G, Timens W, Schmidt M.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Aug;387(8):795-7. doi: 10.1007/s00210-014-1015-z. Epub 2014 Jul 4. No abstract available.

PMID:
24994109
26.

Development and internal validation of a prognostic model to predict recurrence free survival in patients with adult granulosa cell tumors of the ovary.

van Meurs HS, Schuit E, Horlings HM, van der Velden J, van Driel WJ, Mol BW, Kenter GG, Buist MR.

Gynecol Oncol. 2014 Sep;134(3):498-504. doi: 10.1016/j.ygyno.2014.06.021. Epub 2014 Jun 28.

PMID:
24983647
27.

Hormone therapy in ovarian granulosa cell tumors: a systematic review.

van Meurs HS, van Lonkhuijzen LR, Limpens J, van der Velden J, Buist MR.

Gynecol Oncol. 2014 Jul;134(1):196-205. doi: 10.1016/j.ygyno.2014.03.573. Epub 2014 Apr 5. Review.

PMID:
24713548
28.

Arginase inhibition prevents inflammation and remodeling in a guinea pig model of chronic obstructive pulmonary disease.

Pera T, Zuidhof AB, Smit M, Menzen MH, Klein T, Flik G, Zaagsma J, Meurs H, Maarsingh H.

J Pharmacol Exp Ther. 2014 May;349(2):229-38. doi: 10.1124/jpet.113.210138. Epub 2014 Feb 21.

PMID:
24563530
29.

Effectiveness of chemotherapy in measurable granulosa cell tumors: a retrospective study and review of literature.

van Meurs HS, Buist MR, Westermann AM, Sonke GS, Kenter GG, van der Velden J.

Int J Gynecol Cancer. 2014 Mar;24(3):496-505. doi: 10.1097/IGC.0000000000000077. Review.

PMID:
24469325
30.

A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke.

Oldenburger A, Poppinga WJ, Kos F, de Bruin HG, Rijks WF, Heijink IH, Timens W, Meurs H, Maarsingh H, Schmidt M.

Am J Physiol Cell Physiol. 2014 Mar 15;306(6):C585-97. doi: 10.1152/ajpcell.00183.2013. Epub 2014 Jan 22.

31.

Bronchoprotection by olodaterol is synergistically enhanced by tiotropium in a guinea pig model of allergic asthma.

Smit M, Zuidhof AB, Bos SI, Maarsingh H, Gosens R, Zaagsma J, Meurs H.

J Pharmacol Exp Ther. 2014 Feb;348(2):303-10. doi: 10.1124/jpet.113.208439. Epub 2013 Dec 4.

PMID:
24307202
32.

The incidence of endometrial hyperplasia and cancer in 1031 patients with a granulosa cell tumor of the ovary: long-term follow-up in a population-based cohort study.

van Meurs HS, Bleeker MC, van der Velden J, Overbeek LI, Kenter GG, Buist MR.

Int J Gynecol Cancer. 2013 Oct;23(8):1417-22. doi: 10.1097/IGC.0b013e3182a57fb4.

PMID:
24257556
33.

Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.

Kistemaker LE, Bos ST, Mudde WM, Hylkema MN, Hiemstra PS, Wess J, Meurs H, Kerstjens HA, Gosens R.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):690-8. doi: 10.1165/rcmb.2013-0220OC.

PMID:
24156289
34.

Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: I. Effects on lung remodeling and pathology.

Baarsma HA, Bos S, Meurs H, Visser KH, Smit M, Schols AM, Langen RC, Kerstjens HA, Gosens R.

Respir Res. 2013 Oct 23;14:113. doi: 10.1186/1465-9921-14-113.

35.

Levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation (Novasure) in women with heavy menstrual bleeding: a multicentre randomised controlled trial.

Herman MC, van den Brink MJ, Geomini PM, van Meurs HS, Huirne JA, Eising HP, Timmermans A, Pijnenborg JM, Klinkert ER, Coppus SF, Nieboer TE, Catshoek R, van der Voet LF, van Eijndhoven HW, Graziosi GC, Veersema S, van Kesteren PJ, Langenveld J, Smeets NA, van Vliet HA, van der Steeg JW, Lisman-van Leeuwen Y, Dekker JH, Mol BW, Berger MY, Bongers MY.

BMC Womens Health. 2013 Aug 8;13:32. doi: 10.1186/1472-6874-13-32.

36.

Which patients benefit most from primary surgery or neoadjuvant chemotherapy in stage IIIC or IV ovarian cancer? An exploratory analysis of the European Organisation for Research and Treatment of Cancer 55971 randomised trial.

van Meurs HS, Tajik P, Hof MH, Vergote I, Kenter GG, Mol BW, Buist MR, Bossuyt PM.

Eur J Cancer. 2013 Oct;49(15):3191-201. doi: 10.1016/j.ejca.2013.06.013. Epub 2013 Jul 11.

PMID:
23850170
37.

Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices.

Oenema TA, Maarsingh H, Smit M, Groothuis GM, Meurs H, Gosens R.

PLoS One. 2013 Jun 26;8(6):e65580. doi: 10.1371/journal.pone.0065580. Print 2013.

38.

A new perspective on muscarinic receptor antagonism in obstructive airways diseases.

Meurs H, Oenema TA, Kistemaker LE, Gosens R.

Curr Opin Pharmacol. 2013 Jun;13(3):316-23. doi: 10.1016/j.coph.2013.04.004. Epub 2013 May 3. Review.

PMID:
23643733
39.

Surgical versus expectant management in women with an incomplete evacuation of the uterus after treatment with misoprostol for miscarriage: the MisoREST trial.

Verschoor MA, Lemmers M, Bossuyt PM, Graziosi GC, Hajenius PJ, Hendriks DJ, van Hooff MA, van Meurs HS, Opmeer BC, van Tulder MW, Bouwma L, Catshoek R, Geomini P, Klinkert ER, Langenveld J, Nieboer TE, van der Ploeg JM, Radder CM, Spinder T, van der Voet LF, Mol BW, Huirne JA, Ankum WM.

BMC Pregnancy Childbirth. 2013 May 2;13:102. doi: 10.1186/1471-2393-13-102.

40.

Focal adhesion kinase regulates collagen I-induced airway smooth muscle phenotype switching.

Dekkers BG, Spanjer AI, van der Schuyt RD, Kuik WJ, Zaagsma J, Meurs H.

J Pharmacol Exp Ther. 2013 Jul;346(1):86-95. doi: 10.1124/jpet.113.203042. Epub 2013 Apr 16.

PMID:
23591997
41.

Cross-talk between transforming growth factor-β₁ and muscarinic M₂ receptors augments airway smooth muscle proliferation.

Oenema TA, Mensink G, Smedinga L, Halayko AJ, Zaagsma J, Meurs H, Gosens R, Dekkers BG.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):18-27. doi: 10.1165/rcmb.2012-0261OC.

PMID:
23449734
42.

Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice.

Kistemaker LE, Bos IS, Hylkema MN, Nawijn MC, Hiemstra PS, Wess J, Meurs H, Kerstjens HA, Gosens R.

Eur Respir J. 2013 Dec;42(6):1677-88. doi: 10.1183/09031936.00112412. Epub 2013 Feb 8.

43.

Glycogen synthase kinase-3 (GSK-3) regulates TGF-β₁-induced differentiation of pulmonary fibroblasts.

Baarsma HA, Engelbertink LH, van Hees LJ, Menzen MH, Meurs H, Timens W, Postma DS, Kerstjens HA, Gosens R.

Br J Pharmacol. 2013 Jun;169(3):590-603. doi: 10.1111/bph.12098.

44.

The non-neuronal cholinergic system: basic science, therapeutic implications and new perspectives.

Grando SA, Kawashima K, Kirkpatrick CJ, Meurs H, Wessler I.

Life Sci. 2012 Nov 27;91(21-22):969-72. doi: 10.1016/j.lfs.2012.10.004. No abstract available.

PMID:
23141771
45.

Muscarinic receptor stimulation augments TGF-β1-induced contractile protein expression by airway smooth muscle cells.

Oenema TA, Smit M, Smedinga L, Racké K, Halayko AJ, Meurs H, Gosens R.

Am J Physiol Lung Cell Mol Physiol. 2012 Oct 1;303(7):L589-97. doi: 10.1152/ajplung.00400.2011. Epub 2012 Aug 3.

46.

Muscarinic receptors on airway mesenchymal cells: novel findings for an ancient target.

Meurs H, Dekkers BG, Maarsingh H, Halayko AJ, Zaagsma J, Gosens R.

Pulm Pharmacol Ther. 2013 Feb;26(1):145-55. doi: 10.1016/j.pupt.2012.07.003. Epub 2012 Jul 25. Review.

PMID:
22842340
47.

Glucocorticosteroids and β₂-adrenoceptor agonists synergize to inhibit airway smooth muscle remodeling.

Dekkers BG, Pehlic A, Mariani R, Bos IS, Meurs H, Zaagsma J.

J Pharmacol Exp Ther. 2012 Sep;342(3):780-7. doi: 10.1124/jpet.112.195867. Epub 2012 Jun 8.

PMID:
22685341
48.

Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells.

Pera T, Atmaj C, van der Vegt M, Halayko AJ, Zaagsma J, Meurs H.

Am J Physiol Lung Cell Mol Physiol. 2012 Aug 1;303(3):L272-8. doi: 10.1152/ajplung.00291.2011. Epub 2012 Apr 20.

49.

Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD.

Kistemaker LE, Oenema TA, Meurs H, Gosens R.

Life Sci. 2012 Nov 27;91(21-22):1126-33. doi: 10.1016/j.lfs.2012.02.021. Epub 2012 Mar 3. Review.

PMID:
22406302
50.

Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease.

Oldenburger A, Roscioni SS, Jansen E, Menzen MH, Halayko AJ, Timens W, Meurs H, Maarsingh H, Schmidt M.

PLoS One. 2012;7(2):e31574. doi: 10.1371/journal.pone.0031574. Epub 2012 Feb 21.

Supplemental Content

Support Center