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Items: 46

1.

Differential regulation of the Wnt/β-catenin pathway by hepatitis C virus recombinants expressing core from various genotypes.

Aicher S, Kakkanas A, Cohen L, Blumen B, Oprisan G, Njouom R, Meurs EF, Mavromara P, Martin A.

Sci Rep. 2018 Jul 25;8(1):11185. doi: 10.1038/s41598-018-29078-2.

2.

A potential robust antiviral defense state in the common vampire bat: Expression, induction and molecular characterization of the three interferon-stimulated genes -OAS1, ADAR1 and PKR.

Sarkis S, Dabo S, Lise MC, Neuveut C, Meurs EF, Lacoste V, Lavergne A.

Dev Comp Immunol. 2018 Aug;85:95-107. doi: 10.1016/j.dci.2018.04.006. Epub 2018 Apr 7.

PMID:
29635006
3.

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.

Dabo S, Maillard P, Collados Rodriguez M, Hansen MD, Mazouz S, Bigot DJ, Tible M, Janvier G, Helynck O, Cassonnet P, Jacob Y, Bellalou J, Gatignol A, Patel RC, Hugon J, Munier-Lehmann H, Meurs EF.

Sci Rep. 2017 Nov 23;7(1):16129. doi: 10.1038/s41598-017-16089-8.

4.

Development of molecular and cellular tools to decipher the type I IFN pathway of the common vampire bat.

Sarkis S, Lise MC, Darcissac E, Dabo S, Falk M, Chaulet L, Neuveut C, Meurs EF, Lavergne A, Lacoste V.

Dev Comp Immunol. 2018 Apr;81:1-7. doi: 10.1016/j.dci.2017.10.023. Epub 2017 Nov 6.

5.

Genetic variations in toll-like receptors 7 and 8 modulate natural hepatitis C outcomes and liver disease progression.

Fakhir FZ, Lkhider M, Badre W, Alaoui R, Meurs EF, Pineau P, Ezzikouri S, Benjelloun S.

Liver Int. 2018 Mar;38(3):432-442. doi: 10.1111/liv.13533. Epub 2017 Aug 24.

PMID:
28752959
6.

Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.

Hansen MD, Johnsen IB, Stiberg KA, Sherstova T, Wakita T, Richard GM, Kandasamy RK, Meurs EF, Anthonsen MW.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3462-E3471. doi: 10.1073/pnas.1616683114. Epub 2017 Apr 7.

7.

Dual Kinase Inhibition Affords Extended in vitro Neuroprotection in Amyloid-β Toxicity.

Gourmaud S, Mouton-Liger F, Abadie C, Meurs EF, Paquet C, Hugon J.

J Alzheimers Dis. 2016 Oct 18;54(4):1659-1670.

PMID:
27636848
8.

Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline.

Gourmaud S, Paquet C, Dumurgier J, Pace C, Bouras C, Gray F, Laplanche JL, Meurs EF, Mouton-Liger F, Hugon J.

J Psychiatry Neurosci. 2015 May;40(3):151-61.

9.

HIV-1 translation and its regulation by cellular factors PKR and PACT.

Burugu S, Daher A, Meurs EF, Gatignol A.

Virus Res. 2014 Nov 26;193:65-77. doi: 10.1016/j.virusres.2014.07.014. Epub 2014 Jul 23. Review.

PMID:
25064266
10.

NS3 of bluetongue virus interferes with the induction of type I interferon.

Chauveau E, Doceul V, Lara E, Breard E, Sailleau C, Vidalain PO, Meurs EF, Dabo S, Schwartz-Cornil I, Zientara S, Vitour D.

J Virol. 2013 Jul;87(14):8241-6. doi: 10.1128/JVI.00678-13. Epub 2013 May 8.

11.

dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection.

Dabo S, Meurs EF.

Viruses. 2012 Oct 29;4(11):2598-635. doi: 10.3390/v4112598. Review.

12.

The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.

Ruscanu S, Pascale F, Bourge M, Hemati B, Elhmouzi-Younes J, Urien C, Bonneau M, Takamatsu H, Hope J, Mertens P, Meyer G, Stewart M, Roy P, Meurs EF, Dabo S, Zientara S, Breard E, Sailleau C, Chauveau E, Vitour D, Charley B, Schwartz-Cornil I.

J Virol. 2012 May;86(10):5817-28. doi: 10.1128/JVI.06716-11. Epub 2012 Mar 21.

13.

Hepatitis C virus reveals a novel early control in acute immune response.

Arnaud N, Dabo S, Akazawa D, Fukasawa M, Shinkai-Ouchi F, Hugon J, Wakita T, Meurs EF.

PLoS Pathog. 2011 Oct;7(10):e1002289. doi: 10.1371/journal.ppat.1002289. Epub 2011 Oct 13.

14.

The PKR activator PACT is induced by Aβ: involvement in Alzheimer's disease.

Paquet C, Mouton-Liger F, Meurs EF, Mazot P, Bouras C, Pradier L, Gray F, Hugon J.

Brain Pathol. 2012 Mar;22(2):219-29. doi: 10.1111/j.1750-3639.2011.00520.x. Epub 2011 Sep 16.

PMID:
21790829
15.

A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response.

Paz S, Vilasco M, Werden SJ, Arguello M, Joseph-Pillai D, Zhao T, Nguyen TL, Sun Q, Meurs EF, Lin R, Hiscott J.

Cell Res. 2011 Jun;21(6):895-910. doi: 10.1038/cr.2011.2. Epub 2011 Jan 4.

16.

Hepatitis C virus controls interferon production through PKR activation.

Arnaud N, Dabo S, Maillard P, Budkowska A, Kalliampakou KI, Mavromara P, Garcin D, Hugon J, Gatignol A, Akazawa D, Wakita T, Meurs EF.

PLoS One. 2010 May 11;5(5):e10575. doi: 10.1371/journal.pone.0010575.

17.

ER targeting and retention of the HCV NS4B protein relies on the concerted action of multiple structural features including its transmembrane domains.

Boleti H, Smirlis D, Dalagiorgou G, Meurs EF, Christoforidis S, Mavromara P.

Mol Membr Biol. 2010 Jan;27(1):45-62. doi: 10.3109/09687680903426208.

PMID:
20001747
18.

ADAR1 interacts with PKR during human immunodeficiency virus infection of lymphocytes and contributes to viral replication.

Clerzius G, Gélinas JF, Daher A, Bonnet M, Meurs EF, Gatignol A.

J Virol. 2009 Oct;83(19):10119-28. doi: 10.1128/JVI.02457-08. Epub 2009 Jul 15.

19.

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS.

Vitour D, Dabo S, Ahmadi Pour M, Vilasco M, Vidalain PO, Jacob Y, Mezel-Lemoine M, Paz S, Arguello M, Lin R, Tangy F, Hiscott J, Meurs EF.

J Biol Chem. 2009 Aug 14;284(33):21797-809. doi: 10.1074/jbc.M109.018275. Epub 2009 Jun 22.

20.

Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter.

Paz S, Vilasco M, Arguello M, Sun Q, Lacoste J, Nguyen TL, Zhao T, Shestakova EA, Zaari S, Bibeau-Poirier A, Servant MJ, Lin R, Meurs EF, Hiscott J.

Mol Cell Biol. 2009 Jun;29(12):3401-12. doi: 10.1128/MCB.00880-08. Epub 2009 Apr 20.

21.

TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress.

Daher A, Laraki G, Singh M, Melendez-Peña CE, Bannwarth S, Peters AH, Meurs EF, Braun RE, Patel RC, Gatignol A.

Mol Cell Biol. 2009 Jan;29(1):254-65. doi: 10.1128/MCB.01030-08. Epub 2008 Oct 20.

22.

The interferon inducing pathways and the hepatitis C virus.

Meurs EF, Breiman A.

World J Gastroenterol. 2007 May 7;13(17):2446-54. Review.

23.

Regulation of interferon production by RIG-I and LGP2: a lesson in self-control.

Vitour D, Meurs EF.

Sci STKE. 2007 May 1;2007(384):pe20.

PMID:
17473309
24.

The dsRNA protein kinase PKR: virus and cell control.

García MA, Meurs EF, Esteban M.

Biochimie. 2007 Jun-Jul;89(6-7):799-811. Epub 2007 Mar 12. Review.

PMID:
17451862
25.

The protein kinase IKKepsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers.

Vilasco M, Larrea E, Vitour D, Dabo S, Breiman A, Regnault B, Riezu JI, Eid P, Prieto J, Meurs EF.

Hepatology. 2006 Dec;44(6):1635-47.

PMID:
17133498
26.

A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells.

Breiman A, Vitour D, Vilasco M, Ottone C, Molina S, Pichard L, Fournier C, Delgrange D, Charneau P, Duverlie G, Wychowski C, Maurel P, Meurs EF.

J Gen Virol. 2006 Dec;87(Pt 12):3587-98.

PMID:
17098974
27.

The N-terminus of PKR is responsible for the activation of the NF-kappaB signaling pathway by interacting with the IKK complex.

Bonnet MC, Daurat C, Ottone C, Meurs EF.

Cell Signal. 2006 Nov;18(11):1865-75. Epub 2006 Feb 28.

PMID:
16600570
28.

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.

Breiman A, Grandvaux N, Lin R, Ottone C, Akira S, Yoneyama M, Fujita T, Hiscott J, Meurs EF.

J Virol. 2005 Apr;79(7):3969-78.

29.

Positive effect of the hepatitis C virus nonstructural 5A protein on viral multiplication.

Bonte D, François C, Castelain S, Wychowski C, Dubuisson J, Meurs EF, Duverlie G.

Arch Virol. 2004 Jul;149(7):1353-71. Epub 2004 Mar 17.

PMID:
15221536
30.

The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR.

Dorin D, Bonnet MC, Bannwarth S, Gatignol A, Meurs EF, Vaquero C.

J Biol Chem. 2003 Feb 14;278(7):4440-8. Epub 2002 Dec 9.

31.

The role of the phosphorus BI-BII transition in protein-DNA recognition: the NF-kappaB complex.

Wecker K, Bonnet MC, Meurs EF, Delepierre M.

Nucleic Acids Res. 2002 Oct 15;30(20):4452-9.

32.

Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression.

Daher A, Longuet M, Dorin D, Bois F, Segeral E, Bannwarth S, Battisti PL, Purcell DF, Benarous R, Vaquero C, Meurs EF, Gatignol A.

J Biol Chem. 2001 Sep 7;276(36):33899-905. Epub 2001 Jul 3.

33.

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

Bonnet MC, Weil R, Dam E, Hovanessian AG, Meurs EF.

Mol Cell Biol. 2000 Jul;20(13):4532-42.

34.

Expression of hepatitis C virus proteins interferes with the antiviral action of interferon independently of PKR-mediated control of protein synthesis.

François C, Duverlie G, Rebouillat D, Khorsi H, Castelain S, Blum HE, Gatignol A, Wychowski C, Moradpour D, Meurs EF.

J Virol. 2000 Jun;74(12):5587-96.

35.
36.

Colocalization within the nucleolus of two highly related IFN-induced human nuclear phosphoproteins with nucleolin.

Welsh GI, Kadereit S, Coccia EM, Hovanessian AG, Meurs EF.

Exp Cell Res. 1999 Jul 10;250(1):62-74.

PMID:
10388521
37.

Full peptide synthesis, purification, and characterization of six Tat variants. Differences observed between HIV-1 isolates from Africa and other continents.

Péloponèse JM Jr, Collette Y, Grégoire C, Bailly C, Campèse D, Meurs EF, Olive D, Loret EP.

J Biol Chem. 1999 Apr 23;274(17):11473-8.

38.

Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons.

Raveh T, Hovanessian AG, Meurs EF, Sonenberg N, Kimchi A.

J Biol Chem. 1996 Oct 11;271(41):25479-84.

39.

Human PKR transfected into murine cells stimulates expression of genes under control of the HIV1 or HTLV-I LTR.

Meurs EF, McMillan N, Williams BR, Hovanessian AG, Southern PJ.

Virology. 1995 Dec 20;214(2):653-9. Erratum in: Virology 1998 Jul 20;247(1):125.

40.
41.

Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells.

Jeffrey IW, Kadereit S, Meurs EF, Metzger T, Bachmann M, Schwemmle M, Hovanessian AG, Clemens MJ.

Exp Cell Res. 1995 May;218(1):17-27.

PMID:
7737357
42.

Characterization of an interferon-induced 48-kD protein immunologically related to the double-stranded RNA-activated protein kinase PKR.

Kadereit S, Galabru J, Robert N, Meurs EF, Hovanessian AG.

J Interferon Res. 1994 Oct;14(5):251-7. Erratum in: J Interferon Res 1995 Feb;15(2):196.

PMID:
7532201
43.

Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins.

Kadereit S, Gewert DR, Galabru J, Hovanessian AG, Meurs EF.

J Biol Chem. 1993 Nov 15;268(32):24432-41.

44.

Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22.

Squire J, Meurs EF, Chong KL, McMillan NA, Hovanessian AG, Williams BR.

Genomics. 1993 Jun;16(3):768-70.

PMID:
7686884
45.

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.

Meurs EF, Galabru J, Barber GN, Katze MG, Hovanessian AG.

Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):232-6.

46.

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