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Items: 12


Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids.

Chaveroux C, Bruhat A, Carraro V, Jousse C, Averous J, Maurin AC, Parry L, Mesclon F, Muranishi Y, Cordelier P, Meulle A, Baril P, Do Thi A, Ravassard P, Mallet J, Fafournoux P.

Nat Biotechnol. 2016 Jul;34(7):746-51. doi: 10.1038/nbt.3582. Epub 2016 Jun 6.


First-in-man phase 1 clinical trial of gene therapy for advanced pancreatic cancer: safety, biodistribution, and preliminary clinical findings.

Buscail L, Bournet B, Vernejoul F, Cambois G, Lulka H, Hanoun N, Dufresne M, Meulle A, Vignolle-Vidoni A, Ligat L, Saint-Laurent N, Pont F, Dejean S, Gayral M, Martins F, Torrisani J, Barbey O, Gross F, Guimbaud R, Otal P, Lopez F, Tiraby G, Cordelier P.

Mol Ther. 2015 Apr;23(4):779-89. doi: 10.1038/mt.2015.1. Epub 2015 Jan 14.


MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer.

Gayral M, Jo S, Hanoun N, Vignolle-Vidoni A, Lulka H, Delpu Y, Meulle A, Dufresne M, Humeau M, Chalret du Rieu M, Bournet B, Sèlves J, Guimbaud R, Carrère N, Buscail L, Torrisani J, Cordelier P.

World J Gastroenterol. 2014 Aug 28;20(32):11199-209. doi: 10.3748/wjg.v20.i32.11199. Review.


Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases.

Kedinger V, Meulle A, Zounib O, Bonnet ME, Gossart JB, Benoit E, Messmer M, Shankaranarayanan P, Behr JP, Erbacher P, Bolcato-Bellemin AL.

BMC Cancer. 2013 Jul 9;13:338. doi: 10.1186/1471-2407-13-338.


Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition.

Bonnet ME, Gossart JB, Benoit E, Messmer M, Zounib O, Moreau V, Behr JP, Lenne-Samuel N, Kedinger V, Meulle A, Erbacher P, Bolcato-Bellemin AL.

J Control Release. 2013 Sep 10;170(2):183-90. doi: 10.1016/j.jconrel.2013.05.015. Epub 2013 May 29.


Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

Boidot R, Végran F, Meulle A, Le Breton A, Dessy C, Sonveaux P, Lizard-Nacol S, Feron O.

Cancer Res. 2012 Feb 15;72(4):939-48. doi: 10.1158/0008-5472.CAN-11-2474. Epub 2011 Dec 19.


LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line.

Gérard E, Meulle A, Feron O, Marchand-Brynaert J.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):586-90. doi: 10.1016/j.bmcl.2011.10.078. Epub 2011 Oct 31.


Cancer-associated adipocytes promotes breast tumor radioresistance.

Bochet L, Meulle A, Imbert S, Salles B, Valet P, Muller C.

Biochem Biophys Res Commun. 2011 Jul 22;411(1):102-6. doi: 10.1016/j.bbrc.2011.06.101. Epub 2011 Jun 25.


Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion.

Dirat B, Bochet L, Dabek M, Daviaud D, Dauvillier S, Majed B, Wang YY, Meulle A, Salles B, Le Gonidec S, Garrido I, Escourrou G, Valet P, Muller C.

Cancer Res. 2011 Apr 1;71(7):2455-65. doi: 10.1158/0008-5472.CAN-10-3323.


Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.

Masson O, Prébois C, Derocq D, Meulle A, Dray C, Daviaud D, Quilliot D, Valet P, Muller C, Liaudet-Coopman E.

PLoS One. 2011 Feb 2;6(2):e16452. doi: 10.1371/journal.pone.0016452.


LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.

Masson O, Chavey C, Dray C, Meulle A, Daviaud D, Quilliot D, Muller C, Valet P, Liaudet-Coopman E.

PLoS One. 2009 Oct 12;4(10):e7422. doi: 10.1371/journal.pone.0007422.


Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesis.

Meulle A, Salles B, Daviaud D, Valet P, Muller C.

PLoS One. 2008;3(10):e3345. doi: 10.1371/journal.pone.0003345. Epub 2008 Oct 10.

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