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Items: 1 to 50 of 1172

1.

Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia.

Liu P, Wang L, DuBois BG, Colandrea VJ, Liu R, Cai J, Du X, Quan W, Morris W, Bai J, Bishwokarma B, Cheng M, Piesvaux J, Ray K, Alpert C, Chiu CS, Zielstorff M, Metzger JM, Yang L, Leung D, Alleyne C, Vincent SH, Pucci V, Li X, Crespo A, Stickens D, Hale JJ, Ujjainwalla F, Sinz CJ.

ACS Med Chem Lett. 2018 Nov 13;9(12):1193-1198. doi: 10.1021/acsmedchemlett.8b00274. eCollection 2018 Dec 13.

PMID:
30613325
2.

Autonomic dysfunction in Parkinson disease and animal models.

Metzger JM, Emborg ME.

Clin Auton Res. 2019 Jan 2. doi: 10.1007/s10286-018-00584-7. [Epub ahead of print] Review.

PMID:
30604165
3.

Strategic approaches to restoring ecosystems can triple conservation gains and halve costs.

Strassburg BBN, Beyer HL, Crouzeilles R, Iribarrem A, Barros F, de Siqueira MF, Sánchez-Tapia A, Balmford A, Sansevero JBB, Brancalion PHS, Broadbent EN, Chazdon RL, Filho AO, Gardner TA, Gordon A, Latawiec A, Loyola R, Metzger JP, Mills M, Possingham HP, Rodrigues RR, Scaramuzza CAM, Scarano FR, Tambosi L, Uriarte M.

Nat Ecol Evol. 2019 Jan;3(1):62-70. doi: 10.1038/s41559-018-0743-8. Epub 2018 Dec 17.

PMID:
30568285
4.

Scenarios and Models to Support Global Conservation Targets.

Nicholson E, Fulton EA, Brooks TM, Blanchard R, Leadley P, Metzger JP, Mokany K, Stevenson S, Wintle BA, Woolley SNC, Barnes M, Watson JEM, Ferrier S.

Trends Ecol Evol. 2019 Jan;34(1):57-68. doi: 10.1016/j.tree.2018.10.006. Epub 2018 Dec 1. Review.

PMID:
30514580
5.

[Chronic granulomatous disease as a rare differential diagnosis of inflammatory bowel disease].

Metzger JC, Kurz E, von Spee-Mayer C, Kolck G, Bogumil A, Galle PR, Zimmermann T.

Z Gastroenterol. 2018 Dec;56(12):1507-1512. doi: 10.1055/a-0732-5865. Epub 2018 Nov 22. German.

PMID:
30466133
6.

A de Novo EDA-Variant in a Litter of Shorthaired Standard Dachshunds with X-Linked Hypohidrotic Ectodermal Dysplasia.

Vasiliadis D, Hewicker-Trautwein M, Klotz D, Fehr M, Ruseva S, Arndt J, Metzger J, Distl O.

G3 (Bethesda). 2019 Jan 9;9(1):95-104. doi: 10.1534/g3.118.200814.

7.

Breast ultrasound utilization in a safety net emergency department.

Porembka JH, Compton L, Omar L, Sharma P, Clark H, Ahn R, Ganti R, Xi Y, Metzger J, Leyendecker JR.

Emerg Radiol. 2018 Oct 30. doi: 10.1007/s10140-018-1651-6. [Epub ahead of print]

PMID:
30377859
8.

Evaluation of a Novel Rule-Out Myocardial Infarction Protocol Incorporating High-Sensitivity Troponin T in a US Hospital.

Vigen R, Kutscher P, Fernandez F, Yu A, Bertulfo B, Hashim IA, Molberg K, Diercks DB, Metzger JC, Soto J, Alzubaidy D, Thibodeaux L, Joglar JA, de Lemos JA, Das SR.

Circulation. 2018 Oct 30;138(18):2061-2063. doi: 10.1161/CIRCULATIONAHA.118.033861. No abstract available.

PMID:
30372140
9.

Urinary proteomics to diagnose chronic active antibody-mediated rejection in pediatric kidney transplantation - a pilot study.

Kanzelmeyer NK, Zürbig P, Mischak H, Metzger J, Fichtner A, Ruszai KH, Seemann T, Hansen M, Wygoda S, Krupka K, Tönshoff B, Melk A, Pape L.

Transpl Int. 2019 Jan;32(1):28-37. doi: 10.1111/tri.13363. Epub 2018 Nov 12.

PMID:
30357927
10.

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.

Yoney A, Etoc F, Ruzo A, Carroll T, Metzger JJ, Martyn I, Li S, Kirst C, Siggia ED, Brivanlou AH.

Elife. 2018 Oct 12;7. pii: e38279. doi: 10.7554/eLife.38279.

11.

Clinical Proteomics for Post-Hematopoeitic Stem Cell Transplantation Outcomes.

Paczesny S, Metzger J.

Proteomics Clin Appl. 2018 Oct 11:e1800145. doi: 10.1002/prca.201800145. [Epub ahead of print] Review.

PMID:
30307119
12.

Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers.

Houang EM, Sham YY, Bates FS, Metzger JM.

Skelet Muscle. 2018 Oct 10;8(1):31. doi: 10.1186/s13395-018-0177-7. Review.

13.

A recessive lethal chondrodysplasia in a miniature zebu family results from an insertion affecting the chondroitin sulfat domain of aggrecan.

Struck AK, Dierks C, Braun M, Hellige M, Wagner A, Oelmaier B, Beineke A, Metzger J, Distl O.

BMC Genet. 2018 Oct 11;19(1):91. doi: 10.1186/s12863-018-0678-8.

14.

Treatments targeting inotropy.

Maack C, Eschenhagen T, Hamdani N, Heinzel FR, Lyon AR, Manstein DJ, Metzger J, Papp Z, Tocchetti CG, Yilmaz MB, Anker SD, Balligand JL, Bauersachs J, Brutsaert D, Carrier L, Chlopicki S, Cleland JG, de Boer RA, Dietl A, Fischmeister R, Harjola VP, Heymans S, Hilfiker-Kleiner D, Holzmeister J, de Keulenaer G, Limongelli G, Linke WA, Lund LH, Masip J, Metra M, Mueller C, Pieske B, Ponikowski P, Ristic A, Ruschitzka F, Seferovic PM, Skouri H, Zimmermann WH, Mebazaa A.

Eur Heart J. 2018 Oct 8. doi: 10.1093/eurheartj/ehy600. [Epub ahead of print]

PMID:
30295807
15.

Normal cognitive and social development require posterior cerebellar activity.

Badura A, Verpeut JL, Metzger JW, Pereira TD, Pisano TJ, Deverett B, Bakshinskaya DE, Wang SS.

Elife. 2018 Sep 20;7. pii: e36401. doi: 10.7554/eLife.36401.

16.

Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits.

Peripolli E, Metzger J, de Lemos MVA, Stafuzza NB, Kluska S, Olivieri BF, Feitosa FLB, Berton MP, Lopes FB, Munari DP, Lôbo RB, Magnabosco CU, Di Croce F, Osterstock J, Denise S, Pereira ASC, Baldi F.

BMC Genomics. 2018 Sep 17;19(1):680. doi: 10.1186/s12864-018-5060-8.

17.

Association of Batai Virus Infection and Encephalitis in Harbor Seals, Germany, 2016.

Jo WK, Pfankuche VM, Lehmbecker A, Martina B, Rubio-Garcia A, Becker S, Kruppa J, Jung K, Klotz D, Metzger J, Ludlow M, Baumgärtner W, van der Vries E, Osterhaus A.

Emerg Infect Dis. 2018 Sep;24(9):1691-1695. doi: 10.3201/eid2409.171829.

18.

Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency-mediated chronically increased cardiac Ca2+ cycling in vivo.

Law ML, Prins KW, Olander ME, Metzger JM.

Am J Physiol Heart Circ Physiol. 2018 Aug 17. doi: 10.1152/ajpheart.00341.2018. [Epub ahead of print]

PMID:
30118340
19.

In vivo imaging of inflammation and oxidative stress in a nonhuman primate model of cardiac sympathetic neurodegeneration.

Metzger JM, Moore CF, Boettcher CA, Brunner KG, Fleddermann RA, Matsoff HN, Resnikoff HA, Bondarenko V, Kamp TJ, Hacker TA, Barnhart TE, Lao PJ, Christian BT, Nickles RJ, Gallagher CL, Holden JE, Emborg ME.

NPJ Parkinsons Dis. 2018 Jul 13;4:22. doi: 10.1038/s41531-018-0057-1. eCollection 2018.

20.

Synthetic embryology: controlling geometry to model early mammalian development.

Metzger JJ, Simunovic M, Brivanlou AH.

Curr Opin Genet Dev. 2018 Oct;52:86-91. doi: 10.1016/j.gde.2018.06.006. Epub 2018 Jun 27. Review.

PMID:
29957587
21.

Genome data uncover four synergistic key regulators for extremely small body size in horses.

Metzger J, Rau J, Naccache F, Bas Conn L, Lindgren G, Distl O.

BMC Genomics. 2018 Jun 25;19(1):492. doi: 10.1186/s12864-018-4877-5.

22.

Curly coat caused by a keratin 27 variant was transmitted from Fleckvieh into German Angus.

Braun M, Reinartz S, Heppelmann M, Rehage J, Sürie C, Distl O, Metzger J.

Anim Genet. 2018 Aug;49(4):349-350. doi: 10.1111/age.12669. Epub 2018 Jun 22. No abstract available.

PMID:
29932459
23.

Proteomics biomarkers for solid tumors: Current status and future prospects.

Belczacka I, Latosinska A, Metzger J, Marx D, Vlahou A, Mischak H, Frantzi M.

Mass Spectrom Rev. 2019 Jan;38(1):49-78. doi: 10.1002/mas.21572. Epub 2018 Jun 11. Review.

PMID:
29889308
24.

Symptomatic lymphangioma of the adrenal gland: a case report.

Liechti R, Fourie L, Fischli S, Metzger J.

J Surg Case Rep. 2018 May 18;2018(5):rjy106. doi: 10.1093/jscr/rjy106. eCollection 2018 May.

25.

Organophosphonates: A review on environmental relevance, biodegradability and removal in wastewater treatment plants.

Rott E, Steinmetz H, Metzger JW.

Sci Total Environ. 2018 Feb 15;615:1176-1191. doi: 10.1016/j.scitotenv.2017.09.223. Epub 2017 Oct 17. Review.

PMID:
29751423
26.

Renewable Polyethers via GaBr3 -Catalyzed Reduction of Polyesters.

Dannecker PK, Biermann U, von Czapiewski M, Metzger JO, Meier MAR.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8775-8779. doi: 10.1002/anie.201804368. Epub 2018 Jun 6.

PMID:
29722106
27.

An epistatic effect of KRT25 on SP6 is involved in curly coat in horses.

Thomer A, Gottschalk M, Christmann A, Naccache F, Jung K, Hewicker-Trautwein M, Distl O, Metzger J.

Sci Rep. 2018 Apr 23;8(1):6374. doi: 10.1038/s41598-018-24865-3.

28.

TnI Structural Interface with the N-Terminal Lobe of TnC as a Determinant of Cardiac Contractility.

Vetter AD, Houang EM, Sell JJ, Thompson BR, Sham YY, Metzger JM.

Biophys J. 2018 Apr 10;114(7):1646-1656. doi: 10.1016/j.bpj.2018.02.015.

PMID:
29642034
29.

Investigation of human iPSC-derived cardiac myocyte functional maturation by single cell traction force microscopy.

Wheelwright M, Win Z, Mikkila JL, Amen KY, Alford PW, Metzger JM.

PLoS One. 2018 Apr 4;13(4):e0194909. doi: 10.1371/journal.pone.0194909. eCollection 2018.

30.

Urinary CE-MS peptide marker pattern for detection of solid tumors.

Belczacka I, Latosinska A, Siwy J, Metzger J, Merseburger AS, Mischak H, Vlahou A, Frantzi M, Jankowski V.

Sci Rep. 2018 Mar 27;8(1):5227. doi: 10.1038/s41598-018-23585-y.

31.

[Follow-up Care in Cancer: Selected Solid Tumors and Hematological Neoplasias].

Rörden M, Hinterleitner C, Metzger J, Kanz L.

Dtsch Med Wochenschr. 2018 Mar;143(5):334-342. doi: 10.1055/s-0043-124254. Epub 2018 Mar 5. German.

PMID:
29506300
32.

Genetic risk factors for osteochondrosis in various horse breeds.

Naccache F, Metzger J, Distl O.

Equine Vet J. 2018 Sep;50(5):556-563. doi: 10.1111/evj.12824. Epub 2018 Mar 30. Review.

PMID:
29498750
33.

Phylogenetic classification of the world's tropical forests.

Slik JWF, Franklin J, Arroyo-Rodríguez V, Field R, Aguilar S, Aguirre N, Ahumada J, Aiba SI, Alves LF, K A, Avella A, Mora F, Aymard C GA, Báez S, Balvanera P, Bastian ML, Bastin JF, Bellingham PJ, van den Berg E, da Conceição Bispo P, Boeckx P, Boehning-Gaese K, Bongers F, Boyle B, Brambach F, Brearley FQ, Brown S, Chai SL, Chazdon RL, Chen S, Chhang P, Chuyong G, Ewango C, Coronado IM, Cristóbal-Azkarate J, Culmsee H, Damas K, Dattaraja HS, Davidar P, DeWalt SJ, Din H, Drake DR, Duque A, Durigan G, Eichhorn K, Eler ES, Enoki T, Ensslin A, Fandohan AB, Farwig N, Feeley KJ, Fischer M, Forshed O, Garcia QS, Garkoti SC, Gillespie TW, Gillet JF, Gonmadje C, Granzow-de la Cerda I, Griffith DM, Grogan J, Hakeem KR, Harris DJ, Harrison RD, Hector A, Hemp A, Homeier J, Hussain MS, Ibarra-Manríquez G, Hanum IF, Imai N, Jansen PA, Joly CA, Joseph S, Kartawinata K, Kearsley E, Kelly DL, Kessler M, Killeen TJ, Kooyman RM, Laumonier Y, Laurance SG, Laurance WF, Lawes MJ, Letcher SG, Lindsell J, Lovett J, Lozada J, Lu X, Lykke AM, Mahmud KB, Mahayani NPD, Mansor A, Marshall AR, Martin EH, Calderado Leal Matos D, Meave JA, Melo FPL, Mendoza ZHA, Metali F, Medjibe VP, Metzger JP, Metzker T, Mohandass D, Munguía-Rosas MA, Muñoz R, Nurtjahy E, de Oliveira EL, Onrizal, Parolin P, Parren M, Parthasarathy N, Paudel E, Perez R, Pérez-García EA, Pommer U, Poorter L, Qie L, Piedade MTF, Pinto JRR, Poulsen AD, Poulsen JR, Powers JS, Prasad RC, Puyravaud JP, Rangel O, Reitsma J, Rocha DSB, Rolim S, Rovero F, Rozak A, Ruokolainen K, Rutishauser E, Rutten G, Mohd Said MN, Saiter FZ, Saner P, Santos B, Dos Santos JR, Sarker SK, Schmitt CB, Schoengart J, Schulze M, Sheil D, Sist P, Souza AF, Spironello WR, Sposito T, Steinmetz R, Stevart T, Suganuma MS, Sukri R, Sultana A, Sukumar R, Sunderland T, Supriyadi, Suresh HS, Suzuki E, Tabarelli M, Tang J, Tanner EVJ, Targhetta N, Theilade I, Thomas D, Timberlake J, de Morisson Valeriano M, van Valkenburg J, Van Do T, Van Sam H, Vandermeer JH, Verbeeck H, Vetaas OR, Adekunle V, Vieira SA, Webb CO, Webb EL, Whitfeld T, Wich S, Williams J, Wiser S, Wittmann F, Yang X, Adou Yao CY, Yap SL, Zahawi RA, Zakaria R, Zang R.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1837-1842. doi: 10.1073/pnas.1714977115. Epub 2018 Feb 5. Erratum in: Proc Natl Acad Sci U S A. 2018 Mar 12;:.

34.

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.

Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK.

Elife. 2018 Feb 7;7. pii: e32839. doi: 10.7554/eLife.32839.

35.

The Significance of 18F-Fluorocholine-PET/CT as Localizing Imaging Technique in Patients with Primary Hyperparathyroidism and Negative Conventional Imaging.

Fischli S, Suter-Widmer I, Nguyen BT, Müller W, Metzger J, Strobel K, Grünig H, Henzen C.

Front Endocrinol (Lausanne). 2018 Jan 22;8:380. doi: 10.3389/fendo.2017.00380. eCollection 2017.

36.

Chromosomal instability during neurogenesis in Huntington's disease.

Ruzo A, Croft GF, Metzger JJ, Galgoczi S, Gerber LJ, Pellegrini C, Wang H Jr, Fenner M, Tse S, Marks A, Nchako C, Brivanlou AH.

Development. 2018 Jan 29;145(2). pii: dev156844. doi: 10.1242/dev.156844.

37.

Proteomics and Metabolomics for AKI Diagnosis.

Marx D, Metzger J, Pejchinovski M, Gil RB, Frantzi M, Latosinska A, Belczacka I, Heinzmann SS, Husi H, Zoidakis J, Klingele M, Herget-Rosenthal S.

Semin Nephrol. 2018 Jan;38(1):63-87. doi: 10.1016/j.semnephrol.2017.09.007. Review.

PMID:
29291763
38.

ATLANTIC BIRDS: a data set of bird species from the Brazilian Atlantic Forest.

Hasui É, Metzger JP, Pimentel RG, Silveira LF, Bovo AADA, Martensen AC, Uezu A, Regolin AL, Bispo de Oliveira AÂ, Gatto CAFR, Duca C, Andretti CB, Banks-Leite C, Luz D, Mariz D, Alexandrino ER, de Barros FM, Martello F, Pereira IMDS, da Silva JN, Ferraz KMPMDB, Naka LN, Dos Anjos L, Efe MA, Pizo MA, Pichorim M, Gonçalves MSS, Cordeiro PHC, Dias RA, Muylaert RDL, Rodrigues RC, da Costa TVV, Cavarzere V, Tonetti VR, Silva WR, Jenkins CN, Galetti M, Ribeiro MC.

Ecology. 2018 Feb;99(2):497. doi: 10.1002/ecy.2119. Epub 2018 Jan 22.

PMID:
29266462
39.

New Avian Hepadnavirus in Palaeognathous Bird, Germany.

Jo WK, Pfankuche VM, Petersen H, Frei S, Kummrow M, Lorenzen S, Ludlow M, Metzger J, Baumgärtner W, Osterhaus A, van der Vries E.

Emerg Infect Dis. 2017 Dec;23(12):2089-2091. doi: 10.3201/eid2312.161634.

40.

Landscape-level effects on aboveground biomass of tropical forests: A conceptual framework.

Melito M, Metzger JP, de Oliveira AA.

Glob Chang Biol. 2018 Feb;24(2):597-607. doi: 10.1111/gcb.13970. Epub 2017 Nov 27.

PMID:
29095549
41.

Quantifying Binding of Ethylene Oxide-Propylene Oxide Block Copolymers with Lipid Bilayers.

Zhang W, Haman KJ, Metzger JM, Hackel BJ, Bates FS, Lodge TP.

Langmuir. 2017 Nov 7;33(44):12624-12634. doi: 10.1021/acs.langmuir.7b02279. Epub 2017 Oct 25.

42.

All-Atom Molecular Dynamics-Based Analysis of Membrane-Stabilizing Copolymer Interactions with Lipid Bilayers Probed under Constant Surface Tensions.

Houang EM, Bates FS, Sham YY, Metzger JM.

J Phys Chem B. 2017 Nov 30;121(47):10657-10664. doi: 10.1021/acs.jpcb.7b08938. Epub 2017 Nov 20.

PMID:
29049887
43.

Germline mutation within COL2A1 associated with lethal chondrodysplasia in a polled Holstein family.

Reinartz S, Mohwinkel H, Sürie C, Hellige M, Feige K, Eikelberg D, Beineke A, Metzger J, Distl O.

BMC Genomics. 2017 Oct 10;18(1):762. doi: 10.1186/s12864-017-4153-0.

44.

A combined bile and urine proteomic test for cholangiocarcinoma diagnosis in patients with biliary strictures of unknown origin.

Voigtländer T, Metzger J, Schönemeier B, Jäger M, Mischak H, Manns MP, Lankisch TO.

United European Gastroenterol J. 2017 Aug;5(5):668-676. doi: 10.1177/2050640616687836. Epub 2017 Jan 11.

45.

Inclusion of PET-CT into planning of primary or neoadjuvant chemoradiotherapy of esophageal cancer improves prognosis.

Metzger JC, Wollschläger D, Miederer M, Vaupel P, Moehler M, Schmidberger H, Mayer A.

Strahlenther Onkol. 2017 Oct;193(10):791-799. doi: 10.1007/s00066-017-1164-3. Epub 2017 Aug 2.

PMID:
28770295
46.

Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds.

Schaefer RJ, Schubert M, Bailey E, Bannasch DL, Barrey E, Bar-Gal GK, Brem G, Brooks SA, Distl O, Fries R, Finno CJ, Gerber V, Haase B, Jagannathan V, Kalbfleisch T, Leeb T, Lindgren G, Lopes MS, Mach N, da Câmara Machado A, MacLeod JN, McCoy A, Metzger J, Penedo C, Polani S, Rieder S, Tammen I, Tetens J, Thaller G, Verini-Supplizi A, Wade CM, Wallner B, Orlando L, Mickelson JR, McCue ME.

BMC Genomics. 2017 Jul 27;18(1):565. doi: 10.1186/s12864-017-3943-8.

47.

Climate change and sugarcane expansion increase Hantavirus infection risk.

Prist PR, Uriarte M, Fernandes K, Metzger JP.

PLoS Negl Trop Dis. 2017 Jul 20;11(7):e0005705. doi: 10.1371/journal.pntd.0005705. eCollection 2017 Jul.

48.

Y Chromosome Uncovers the Recent Oriental Origin of Modern Stallions.

Wallner B, Palmieri N, Vogl C, Rigler D, Bozlak E, Druml T, Jagannathan V, Leeb T, Fries R, Tetens J, Thaller G, Metzger J, Distl O, Lindgren G, Rubin CJ, Andersson L, Schaefer R, McCue M, Neuditschko M, Rieder S, Schlötterer C, Brem G.

Curr Biol. 2017 Jul 10;27(13):2029-2035.e5. doi: 10.1016/j.cub.2017.05.086. Epub 2017 Jun 29.

49.

Acceptance of Ambulatory Laparoscopic Cholecystectomy in Central Switzerland.

Widjaja SP, Fischer H, Brunner AR, Honigmann P, Metzger J.

World J Surg. 2017 Nov;41(11):2731-2734. doi: 10.1007/s00268-017-4098-0.

PMID:
28660320
50.

Landscape, Climate and Hantavirus Cardiopulmonary Syndrome Outbreaks.

Prist PR, D Andrea PS, Metzger JP.

Ecohealth. 2017 Sep;14(3):614-629. doi: 10.1007/s10393-017-1255-8. Epub 2017 Jun 15. Review.

PMID:
28620680

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