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Evaluation of Pneumococcal Surface Protein A as a Vaccine Antigen against Secondary Streptococcus pneumoniae Challenge during Influenza A Infection.

Roberts S, Williams CM, Salmon SL, Bonin JL, Metzger DW, Furuya Y.

Vaccines (Basel). 2019 Oct 11;7(4). pii: E146. doi: 10.3390/vaccines7040146.


Clinical Outcomes Prior to and Following Complete Everolimus-Eluting Bioresorbable Scaffold Resorption: Five-Year Follow-Up From the ABSORB III Trial.

Kereiakes DJ, Ellis SG, Metzger DC, Caputo RP, Rizik DG, Teirstein PS, Litt MR, Kini A, Kabour A, Marx SO, Popma JJ, Tan SH, Ediebah DE, Simonton C, Stone GW; ABSORB III Investigators.

Circulation. 2019 Sep 25. doi: 10.1161/CIRCULATIONAHA.119.042584. [Epub ahead of print]


Practice Patterns and Prognostic Value of Sentinel Lymph Node Biopsy for Thick Melanoma: A National Cancer Database Study.

Song Y, Azari FS, Metzger DA, Fraker DL, Karakousis GC.

Ann Surg Oncol. 2019 Sep 4. doi: 10.1245/s10434-019-07783-0. [Epub ahead of print]


Association Between Hypertension, Platelet Reactivity, and the Risk of Adverse Events After Percutaneous Coronary Intervention (From the ADAPT-DES Study).

Redfors B, Chen S, Ben-Yehuda O, Huang X, Witzenbichler B, Weisz G, Liu Y, Brodie BR, Rinaldi MJ, Neumann FJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Mazzaferri EL Jr, Mehran R, Stuckey TD, Kirtane AJ, Stone GW.

Am J Cardiol. 2019 Nov 1;124(9):1380-1388. doi: 10.1016/j.amjcard.2019.07.044. Epub 2019 Aug 7.


Compartmentalized effects of aging on group 2 innate lymphoid cell development and function.

D'Souza SS, Shen X, Fung ITH, Ye L, Kuentzel M, Chittur SV, Furuya Y, Siebel CW, Maillard IP, Metzger DW, Yang Q.

Aging Cell. 2019 Aug 20:e13019. doi: 10.1111/acel.13019. [Epub ahead of print]


Is Age a Risk Factor for Cerebral Edema in Children With Diabetic Ketoacidosis? A Literature Review.

Glackin S, Metzger D, Hanas R, Chanoine JP.

Can J Diabetes. 2019 May 7. pii: S1499-2671(18)30709-3. doi: 10.1016/j.jcjd.2019.04.013. [Epub ahead of print] Review.


Allergic Airway Disease Prevents Lethal Synergy of Influenza A Virus-Streptococcus pneumoniae Coinfection.

Roberts S, Salmon SL, Steiner DJ, Williams CM, Metzger DW, Furuya Y.

MBio. 2019 Jul 2;10(4). pii: e01335-19. doi: 10.1128/mBio.01335-19.


Long-Term Clinical Effectiveness of a Drug-Coated Balloon for the Treatment of Femoropopliteal Lesions.

Laird JA, Schneider PA, Jaff MR, Brodmann M, Zeller T, Metzger DC, Krishnan P, Scheinert D, Micari A, Wang H, Masters M, Tepe G.

Circ Cardiovasc Interv. 2019 Jun;12(6):e007702. doi: 10.1161/CIRCINTERVENTIONS.118.007702. Epub 2019 Jun 14.


Derivation and external validation of a novel risk score for prediction of 30-day mortality after percutaneous coronary intervention.

Brener SJ, Leon MB, Serruys PW, Smits PC, von Birgelen C, Mehran R, Kirtane AJ, Witzenbichler B, Rinaldi MJ, Metzger DC, Mazzaferri EL Jr, Zhang Z, Stone GW; Collaborators.

EuroIntervention. 2019 Aug 9;15(6):e551-e557. doi: 10.4244/EIJ-D-19-00262.


Aging Exacerbates Ischemia-Reperfusion-Induced Mitochondrial Respiration Impairment in Skeletal Muscle.

Paradis S, Charles AL, Georg I, Goupilleau F, Meyer A, Kindo M, Laverny G, Metzger D, Geny B.

Antioxidants (Basel). 2019 Jun 8;8(6). pii: E168. doi: 10.3390/antiox8060168.


Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates.

Vonarburg C, Loetscher M, Spycher MO, Kropf A, Illi M, Salmon S, Roberts S, Steinfuehrer K, Campbell I, Koernig S, Bain J, Edler M, Baumann U, Miescher S, Metzger DW, Schaub A, Käsermann F, Zuercher AW.

Respir Res. 2019 May 22;20(1):99. doi: 10.1186/s12931-019-1057-3.


Placebo-controlled randomized clinical trial testing the efficacy and safety of varenicline for smokers with HIV.

Ashare RL, Thompson M, Serrano K, Leone F, Metzger D, Frank I, Gross R, Hole A, Mounzer K, Collman RG, Wileyto EP, Schnoll R.

Drug Alcohol Depend. 2019 Jul 1;200:26-33. doi: 10.1016/j.drugalcdep.2019.03.011. Epub 2019 May 7.


Differences in the rate of nicotine metabolism among smokers with and without HIV.

Ashare RL, Thompson M, Leone F, Metzger D, Gross R, Mounzer K, Tyndale RF, Lerman C, Mahoney MC, Cinciripini P, George TP, Collman RG, Schnoll R.

AIDS. 2019 May 1;33(6):1083-1088. doi: 10.1097/QAD.0000000000002127.


Skeletal Muscle-Specific Activation of Gq Signaling Maintains Glucose Homeostasis.

Bone DBJ, Meister J, Knudsen JR, Dattaroy D, Cohen A, Lee R, Lu H, Metzger D, Jensen TE, Wess J.

Diabetes. 2019 Jun;68(6):1341-1352. doi: 10.2337/db18-0796. Epub 2019 Apr 1.


Designing an Individually Tailored Multilevel Intervention to Increase Engagement in HIV and Substance Use Treatment Among People Who Inject Drugs With HIV: HPTN 074.

Lancaster KE, Miller WC, Kiriazova T, Sarasvita R, Bui Q, Ha TV, Dumchev K, Susami H, Hamilton EL, Rose S, Hershow RB, Go VF, Metzger D, Hoffman IF, Latkin CA.

AIDS Educ Prev. 2019 Apr;31(2):95-110. doi: 10.1521/aeap.2019.31.2.95.


Adverse events in patients with high platelet reactivity following successful chronic total occlusion PCI: The Assessment of Dual AntiPlatelet Therapy with Drug-Eluting Stents (ADAPT-DES) study.

Finn MT, Redfors B, Karmpaliotis D, Kirtane AJ, Green P, McAndrew T, Liu M, Cloney MB, Witzenbichler B, Weisz G, Stuckey TD, Brodie BR, Rinaldi MJ, Neumann FJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Mazzaferri EL Jr, Mehran R, Stone GW.

Am Heart J. 2019 May;211:68-76. doi: 10.1016/j.ahj.2019.02.002. Epub 2019 Feb 20.


Glucocorticoid-immune response to acute stress in women and men living with HIV.

Hantsoo L, Kornfield S, Iannelli C, Podcasy J, Metzger D, Sammel MD, Epperson CN.

J Behav Med. 2019 Mar 19. doi: 10.1007/s10865-019-00029-0. [Epub ahead of print]


Influenza and Staphylococcus aureus Coinfection: TLR9 at Play.

Sun K, Metzger DW.

Trends Microbiol. 2019 May;27(5):383-384. doi: 10.1016/j.tim.2019.02.006. Epub 2019 Mar 11.


Senescence controls prostatic neoplasia driven by Pten loss.

Parisotto M, Grelet E, El Bizri R, Metzger D.

Mol Cell Oncol. 2018 Nov 23;6(1):1511205. doi: 10.1080/23723556.2018.1511205. eCollection 2019.


Relationship Between Intravascular Ultrasound Guidance and Clinical Outcomes After Drug-Eluting Stents.

Maehara A, Mintz GS, Witzenbichler B, Weisz G, Neumann FJ, Rinaldi MJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Brodie BR, Stuckey TD, Mazzaferri EL Jr, McAndrew T, Généreux P, Mehran R, Kirtane AJ, Stone GW.

Circ Cardiovasc Interv. 2018 Nov;11(11):e006243. doi: 10.1161/CIRCINTERVENTIONS.117.006243.


Emergence of Kaposi's Sarcoma Herpesvirus-Associated Complications Following Corticosteroid Use in TB-IRIS.

Manion M, Uldrick T, Polizzotto MN, Sheikh V, Roby G, Lurain K, Metzger D, Mican JM, Pau A, Lisco A, Laidlaw E, Hammoud DA, Whitby D, Yarchoan R, Sereti I.

Open Forum Infect Dis. 2018 Oct 12;5(10):ofy217. doi: 10.1093/ofid/ofy217. eCollection 2018 Oct.


A First-in-Human Evaluation of a Novel Mesh-Covered Stent for Treatment of Carotid Stenosis in Patients at High Risk for Endarterectomy: 30-Day Results of the SCAFFOLD Trial.

Schneider PA, Levy E, Bacharach JM, Metzger DC, Randall B, Garcia A, Siddiqui A, Schonholz C, Gray W.

JACC Cardiovasc Interv. 2018 Dec 10;11(23):2396-2404. doi: 10.1016/j.jcin.2018.07.040.


Impact of Point-of-Care Platelet Function Testing Among Patients With and Without Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents (from the ADAPT-DES Study).

Rinaldi MJ, Gohs FX, Kirtane AJ, Brodie BR, Stuckey TD, Redfors B, McAndrew T, Witzenbichler B, Weisz G, Neumann FJ, Metzger DC, Maehara A, Généreux P, Mehran R, Stone GW.

Am J Cardiol. 2019 Feb 15;123(4):549-557. doi: 10.1016/j.amjcard.2018.11.026. Epub 2018 Nov 23.


[How to limit the progression of PTEN-deficient prostatic tumors?]

Grelet É, Parisotto M, Metzger D.

Med Sci (Paris). 2018 Nov;34(11):904-906. doi: 10.1051/medsci/2018224. Epub 2018 Dec 10. French. No abstract available.


PGC-1β modulates statin-associated myotoxicity in mice.

Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J.

Arch Toxicol. 2019 Feb;93(2):487-504. doi: 10.1007/s00204-018-2369-7. Epub 2018 Dec 3.


Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition.

Liu W, Shao PP, Liang GB, Bawiec J, He J, Aster SD, Wu M, Chicchi G, Wang J, Tsao KL, Shang J, Salituro G, Zhou YP, Li C, Akiyama TE, Metzger DE, Murphy BA, Howard AD, Weber AE, Duffy JL.

ACS Med Chem Lett. 2018 Sep 12;9(11):1082-1087. doi: 10.1021/acsmedchemlett.8b00305. eCollection 2018 Nov 8.


S100A14 Is Increased in Activated NK Cells and Plasma of HIV-Exposed Seronegative People Who Inject Drugs and Promotes Monocyte-NK Crosstalk.

Colón K, Speicher DW, Smith P, Taylor M, Metzger DS, Montaner LJ, Tomescu C.

J Acquir Immune Defic Syndr. 2019 Feb 1;80(2):234-241. doi: 10.1097/QAI.0000000000001911.


Brief Report: Rate of Nicotine Metabolism and Tobacco Use Among Persons With HIV: Implications for Treatment and Research.

Schnoll RA, Thompson M, Serrano K, Leone F, Metzger D, Frank I, Gross R, Mounzer K, Tyndale RF, Weisbrot J, Meline M, Collman RG, Ashare RL.

J Acquir Immune Defic Syndr. 2019 Feb 1;80(2):e36-e40. doi: 10.1097/QAI.0000000000001895.


Prediction of Ischemic and Bleeding Events Using the Dual Antiplatelet Therapy Score in an Unrestricted Percutaneous Coronary Intervention Population.

Brener SJ, Kirtane AJ, Rinaldi MJ, Stuckey TD, Witzenbichler B, Weisz G, Neumann FJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Mazzaferri EL Jr, Gurbel PA, Brodie BR, Mehran R, McAndrew T, Stone GW.

Circ Cardiovasc Interv. 2018 Oct;11(10):e006853. doi: 10.1161/CIRCINTERVENTIONS.118.006853.


Regional differences between people who inject drugs in an HIV prevention trial integrating treatment and prevention (HPTN 074): a baseline analysis.

Lancaster KE, Hoffman IF, Hanscom B, Ha TV, Dumchev K, Susami H, Rose S, Go VF, Reifeis SA, Mollan KR, Hudgens MG, Piwowar-Manning EM, Richardson P, Dvoriak S, Djoerban Z, Kiriazova T, Zeziulin O, Djauzi S, Ahn CV, Latkin C, Metzger D, Burns DN, Sugarman J, Strathdee SA, Eshleman SH, Clarke W, Donnell D, Emel L, Sunner LE, McKinstry L, Sista N, Hamilton EL, Lucas JP, Duong BD, Van Vuong N, Sarasvita R, Miller WC; HPTN 074 Study Team.

J Int AIDS Soc. 2018 Oct;21(10):e25195. doi: 10.1002/jia2.25195.


Client and Provider Perspectives on Antiretroviral Treatment Uptake and Adherence Among People Who Inject Drugs in Indonesia, Ukraine and Vietnam: HPTN 074.

Go VF, Hershow RB, Kiriazova T, Sarasvita R, Bui Q, Latkin CA, Rose S, Hamilton E, Lancaster KE, Metzger D, Hoffman IF, Miller WC.

AIDS Behav. 2019 Apr;23(4):1084-1093. doi: 10.1007/s10461-018-2307-y.


A solution to Nature's haemoglobin knockout: a plasma-accessible carbonic anhydrase catalyses CO2 excretion in Antarctic icefish gills.

Harter TS, Sackville MA, Wilson JM, Metzger DCH, Egginton S, Esbaugh AJ, Farrell AP, Brauner CJ.

J Exp Biol. 2018 Nov 19;221(Pt 22). pii: jeb190918. doi: 10.1242/jeb.190918.


Blinded outcomes and angina assessment of coronary bioresorbable scaffolds: 30-day and 1-year results from the ABSORB IV randomised trial.

Stone GW, Ellis SG, Gori T, Metzger DC, Stein B, Erickson M, Torzewski J, Williams J Jr, Lawson W, Broderick TM, Kabour A, Piegari G, Cavendish J, Bertolet B, Choi JW, Marx SO, Généreux P, Kereiakes DJ; ABSORB IV Investigators.

Lancet. 2018 Oct 27;392(10157):1530-1540. doi: 10.1016/S0140-6736(18)32283-9. Epub 2018 Sep 25. Erratum in: Lancet. 2019 Oct 5;394(10205):1230.


Evaluation of intracoronary hyperoxemic oxygen therapy in acute anterior myocardial infarction: The IC-HOT study.

David SW, Khan ZA, Patel NC, Metzger DC, Wood FO, Wasserman HS, Lotfi AS, Hanson ID, Dixon SR, LaLonde TA, Généreux P, Ozan MO, Maehara A, Stone GW.

Catheter Cardiovasc Interv. 2019 Apr 1;93(5):882-890. doi: 10.1002/ccd.27905. Epub 2018 Sep 28.


Increased Metabolic Activity on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Human Immunodeficiency Virus-Associated Immune Reconstitution Inflammatory Syndrome.

Hammoud DA, Boulougoura A, Papadakis GZ, Wang J, Dodd LE, Rupert A, Higgins J, Roby G, Metzger D, Laidlaw E, Mican JM, Pau A, Lage S, Wong CS, Lisco A, Manion M, Sheikh V, Millo C, Sereti I.

Clin Infect Dis. 2019 Jan 7;68(2):229-238. doi: 10.1093/cid/ciy454.


Impact of high on-aspirin platelet reactivity on outcomes following successful percutaneous coronary intervention with drug-eluting stents.

Chung CJ, Kirtane AJ, Zhang Y, Witzenbichler B, Weisz G, Stuckey TD, Brodie BR, Rinaldi MJ, Neumann FJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Mazzaferri EL Jr, Mehran R, Stone GW.

Am Heart J. 2018 Nov;205:77-86. doi: 10.1016/j.ahj.2018.07.020. Epub 2018 Aug 15.


A scalable, integrated intervention to engage people who inject drugs in HIV care and medication-assisted treatment (HPTN 074): a randomised, controlled phase 3 feasibility and efficacy study.

Miller WC, Hoffman IF, Hanscom BS, Ha TV, Dumchev K, Djoerban Z, Rose SM, Latkin CA, Metzger DS, Lancaster KE, Go VF, Dvoriak S, Mollan KR, Reifeis SA, Piwowar-Manning EM, Richardson P, Hudgens MG, Hamilton EL, Sugarman J, Eshleman SH, Susami H, Chu VA, Djauzi S, Kiriazova T, Bui DD, Strathdee SA, Burns DN.

Lancet. 2018 Sep 1;392(10149):747-759. doi: 10.1016/S0140-6736(18)31487-9.


Chronic benzodiazepine suppresses translocator protein and elevates amyloid β in mice.

Tan S, Metzger DB, Jung ME.

Pharmacol Biochem Behav. 2018 Sep;172:59-67. doi: 10.1016/j.pbb.2018.07.005. Epub 2018 Jul 18.


Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver.

Della Torre S, Mitro N, Meda C, Lolli F, Pedretti S, Barcella M, Ottobrini L, Metzger D, Caruso D, Maggi A.

Cell Metab. 2018 Aug 7;28(2):256-267.e5. doi: 10.1016/j.cmet.2018.05.021. Epub 2018 Jun 14.


Platelet Reactivity and Risk of Ischemic Stroke After Coronary Drug-Eluting Stent Implantation: From the ADAPT-DES Study.

Giustino G, Redfors B, Kirtane AJ, Mehran R, Dangas GD, Witzenbichler B, Neumann FJ, Weisz G, Généreux P, Maehara A, McAndrew T, Farhan S, Rinaldi MJ, Metzger DC, Henry TD, Cox DA, Duffy PL, Mazzaferri EL Jr, Brodie BR, Stuckey TD, Gurbel P, Ben-Yehuda O, Stone GW.

JACC Cardiovasc Interv. 2018 Jul 9;11(13):1277-1286. doi: 10.1016/j.jcin.2018.01.263. Epub 2018 Jun 13.


Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

Pottecher J, Adamopoulos C, Lejay A, Bouitbir J, Charles AL, Meyer A, Singer M, Wolff V, Diemunsch P, Laverny G, Metzger D, Geny B.

Front Physiol. 2018 May 22;9:579. doi: 10.3389/fphys.2018.00579. eCollection 2018.


WHO height charts can be safely substituted when calculating BP Z-scores in a North American clinic setting.

Rodd CJ, Metzger DL, Sharma AK.

Paediatr Child Health. 2018 May;23(3):176-178. doi: 10.1093/pch/pxx185. Epub 2017 Nov 28.


Effects of Influenza on Alveolar Macrophage Viability Are Dependent on Mouse Genetic Strain.

Califano D, Furuya Y, Metzger DW.

J Immunol. 2018 Jul 1;201(1):134-144. doi: 10.4049/jimmunol.1701406. Epub 2018 May 14.


Prevalence of HIV Viral Load Suppression Among Psychiatric Inpatients with Comorbid Substance Use Disorders.

Coviello DM, Lovato R, Apostol K, Eisenberg MM, Metzger DS, Szucs-Reed R, Kiryankova-Dalseth N, Kelly D, Jackson A, Plano M, Blank MB.

Community Ment Health J. 2018 Nov;54(8):1146-1153. doi: 10.1007/s10597-018-0284-2. Epub 2018 May 11.


PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo.

Parisotto M, Grelet E, El Bizri R, Dai Y, Terzic J, Eckert D, Gargowitsch L, Bornert JM, Metzger D.

J Exp Med. 2018 Jun 4;215(6):1749-1763. doi: 10.1084/jem.20171207. Epub 2018 May 9.


Prevalence and Severity of High Blood Pressure Among Children Based on the 2017 American Academy of Pediatrics Guidelines.

Sharma AK, Metzger DL, Rodd CJ.

JAMA Pediatr. 2018 Jun 1;172(6):557-565. doi: 10.1001/jamapediatrics.2018.0223.


DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates.

McLaren DG, Han S, Murphy BA, Wilsie L, Stout SJ, Zhou H, Roddy TP, Gorski JN, Metzger DE, Shin MK, Reilly DF, Zhou HH, Tadin-Strapps M, Bartz SR, Cumiskey AM, Graham TH, Shen DM, Akinsanya KO, Previs SF, Imbriglio JE, Pinto S.

Cell Metab. 2018 Jun 5;27(6):1236-1248.e6. doi: 10.1016/j.cmet.2018.04.004. Epub 2018 Apr 26.


Influenza Vaccination Protects Against Pandemic H1N1 Infection in Sickle Cell Disease Mice.

Roberts S, Metzger DW, Szczepanek SM.

Viral Immunol. 2018 Jul/Aug;31(6):470-471. doi: 10.1089/vim.2018.0024. Epub 2018 Apr 24.


Glucose control and autonomic response during acute stress in youth with type 1 diabetes: A pilot study.

Guan L, Metzger DL, Lavoie PM, Collet JP.

Pediatr Diabetes. 2018 Aug;19(5):1020-1024. doi: 10.1111/pedi.12680. Epub 2018 May 7.


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