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Items: 1 to 50 of 177

1.

Drug Discovery and Repurposing Inhibits a Major Gut Pathogen-Derived Oncogenic Toxin.

Metz P, Tjan MJH, Wu S, Pervaiz M, Hermans S, Shettigar A, Sears CL, Ritschel T, Dutilh BE, Boleij A.

Front Cell Infect Microbiol. 2019 Oct 25;9:364. doi: 10.3389/fcimb.2019.00364. eCollection 2019.

2.

Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents.

Sayed AR, Gomha SM, Abdelrazek FM, Farghaly MS, Hassan SA, Metz P.

BMC Chem. 2019 Sep 24;13(1):116. doi: 10.1186/s13065-019-0632-5. eCollection 2019 Dec.

3.

An efficient synthesis of the guaiane sesquiterpene (-)-isoguaiene by domino metathesis.

Wang Y, Darweesh AF, Zimdars P, Metz P.

Beilstein J Org Chem. 2019 Apr 9;15:858-862. doi: 10.3762/bjoc.15.83. eCollection 2019.

4.

One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents.

Abdelrazek FM, Gomha SM, Shaaban MEB, Rabee KA, El-Shemy HN, Abdallah AM, Metz P.

Mini Rev Med Chem. 2019;19(6):527-538. doi: 10.2174/1389557518666181019124104.

PMID:
30360710
5.

A quantitative metabolomics study of bacterial metabolites in different domains.

Zhong F, Xu M, Metz P, Ghosh-Dastidar P, Zhu J.

Anal Chim Acta. 2018 Dec 11;1037:237-244. doi: 10.1016/j.aca.2018.02.046. Epub 2018 Feb 23.

PMID:
30292298
6.

Efficient directly emitting high-power Tb3+:LiLuF4 laser operating at 587.5  nm in the yellow range.

Castellano-Hernández E, Metz PW, Demesh M, Kränkel C.

Opt Lett. 2018 Oct 1;43(19):4791-4794. doi: 10.1364/OL.43.004791.

PMID:
30272741
7.

Total Synthesis of the Neoclerodane Diterpene Salvinorin A via an Intramolecular Diels-Alder Strategy.

Wang Y, Metz P.

Org Lett. 2018 Jun 1;20(11):3418-3421. doi: 10.1021/acs.orglett.8b01357. Epub 2018 May 22.

PMID:
29787286
8.

Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution.

Keßberg A, Lübken T, Metz P.

Org Lett. 2018 May 18;20(10):3006-3009. doi: 10.1021/acs.orglett.8b01034. Epub 2018 May 2.

PMID:
29718674
9.

Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance.

Klann JE, Kim SH, Remedios KA, He Z, Metz PJ, Lopez J, Tysl T, Olvera JG, Ablack JN, Cantor JM, Boland BS, Yeo G, Zheng Y, Lu LF, Bui JD, Ginsberg MH, Petrich BG, Chang JT.

J Immunol. 2018 Jun 15;200(12):4012-4023. doi: 10.4049/jimmunol.1800112. Epub 2018 Apr 27.

10.

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

Chung L, Orberg ET, Geis AL, Chan JL, Fu K, DeStefano Shields CE, Dejea CM, Fathi P, Chen J, Finard BB, Tam AJ, McAllister F, Fan H, Wu X, Ganguly S, Lebid A, Metz P, Van Meerbeke SW, Huso DL, Wick EC, Pardoll DM, Wan F, Wu S, Sears CL, Housseau F.

Cell Host Microbe. 2018 Mar 14;23(3):421. doi: 10.1016/j.chom.2018.02.004. No abstract available.

11.

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon.

Mutz P, Metz P, Lempp FA, Bender S, Qu B, Schöneweis K, Seitz S, Tu T, Restuccia A, Frankish J, Dächert C, Schusser B, Koschny R, Polychronidis G, Schemmer P, Hoffmann K, Baumert TF, Binder M, Urban S, Bartenschlager R.

Gastroenterology. 2018 May;154(6):1791-1804.e22. doi: 10.1053/j.gastro.2018.01.044. Epub 2018 Feb 1.

12.

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

Chung L, Thiele Orberg E, Geis AL, Chan JL, Fu K, DeStefano Shields CE, Dejea CM, Fathi P, Chen J, Finard BB, Tam AJ, McAllister F, Fan H, Wu X, Ganguly S, Lebid A, Metz P, Van Meerbeke SW, Huso DL, Wick EC, Pardoll DM, Wan F, Wu S, Sears CL, Housseau F.

Cell Host Microbe. 2018 Feb 14;23(2):203-214.e5. doi: 10.1016/j.chom.2018.01.007. Epub 2018 Feb 1. Erratum in: Cell Host Microbe. 2018 Mar 14;23 (3):421.

13.

Formal Synthesis of (-)-Codeine by Application of Temporary Thio Derivatization.

Rautschek J, Jäger A, Metz P.

Org Lett. 2018 Feb 2;20(3):832-835. doi: 10.1021/acs.orglett.7b03972. Epub 2018 Jan 22.

PMID:
29356553
14.

Enantioselective Total Synthesis of 3β-Hydroxy-7β-kemp-8(9)-en-6-one, a Diterpene Isolated from Higher Termites.

Wang Y, Jäger A, Gruner M, Lübken T, Metz P.

Angew Chem Int Ed Engl. 2017 Dec 11;56(50):15861-15865. doi: 10.1002/anie.201708561. Epub 2017 Nov 15.

PMID:
28960721
15.

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR 3rd, Goldrath AW, Overkleeft HS, Ovaa H, Chang JT.

J Clin Invest. 2017 Oct 2;127(10):3609-3623. doi: 10.1172/JCI90895. Epub 2017 Aug 28.

16.

Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution.

Qin T, Metz P.

Org Lett. 2017 Jun 2;19(11):2981-2984. doi: 10.1021/acs.orglett.7b01218. Epub 2017 May 23.

PMID:
28534398
17.

Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool.

Klann JE, Remedios KA, Kim SH, Metz PJ, Lopez J, Mack LA, Zheng Y, Ginsberg MH, Petrich BG, Chang JT.

J Immunol. 2017 Jun 15;198(12):4639-4651. doi: 10.4049/jimmunol.1601165. Epub 2017 May 17.

18.

Performance and wavelength tuning of green emitting terbium lasers.

Metz PW, Marzahl DT, Huber G, Kränkel C.

Opt Express. 2017 Mar 6;25(5):5716-5724. doi: 10.1364/OE.25.005716.

PMID:
28380828
19.

The critical role of point defects in improving the specific capacitance of δ-MnO2 nanosheets.

Gao P, Metz P, Hey T, Gong Y, Liu D, Edwards DD, Howe JY, Huang R, Misture ST.

Nat Commun. 2017 Feb 23;8:14559. doi: 10.1038/ncomms14559.

20.

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing.

Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath AW, Chang JT, Yeo GW.

Nat Immunol. 2017 Apr;18(4):422-432. doi: 10.1038/ni.3688. Epub 2017 Feb 20.

21.

A conceptually novel construction of the 6a-hydroxypterocarpan skeleton - Synthesis of (±)-variabilin.

Ciesielski P, Metz P.

Bioorg Med Chem. 2017 Nov 15;25(22):6175-6177. doi: 10.1016/j.bmc.2017.01.003. Epub 2017 Jan 5.

PMID:
28110821
22.
23.

Enantioselective Synthesis of Guaianolides in the Osmitopsin Family by Domino Metathesis.

Barthel A, Kaden F, Jäger A, Metz P.

Org Lett. 2016 Jul 1;18(13):3298-301. doi: 10.1021/acs.orglett.6b01619. Epub 2016 Jun 22.

PMID:
27333451
24.

[En Route for Objective Evaluation of Form, Volume, and Symmetry in Plastic Surgery using 3-D Intraoperative Scans].

Koban KC, Schenck T, Metz PM, Volkmer E, Haertnagl F, Titze V, Giunta RE.

Handchir Mikrochir Plast Chir. 2016 Apr;48(2):78-84. doi: 10.1055/s-0042-104506. Epub 2016 Apr 21. German.

PMID:
27100943
25.

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition.

Banno A, Garcia DA, van Baarsel ED, Metz PJ, Fisch K, Widjaja CE, Kim SH, Lopez J, Chang AN, Geurink PP, Florea BI, Overkleeft HS, Ovaa H, Bui JD, Yang J, Chang JT.

Oncotarget. 2016 Apr 19;7(16):21527-41. doi: 10.18632/oncotarget.7596.

26.

Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates.

Metz PJ, Lopez J, Kim SH, Akimoto K, Ohno S, Chang JT.

Sci Rep. 2016 Jan 14;6:19182. doi: 10.1038/srep19182.

27.

Utilizing an o-Quinone Methide in Asymmetric Transfer Hydrogenation: Enantioselective Synthesis of Brosimine A, Brosimine B, and Brosimacutin L.

Keßberg A, Metz P.

Angew Chem Int Ed Engl. 2016 Jan 18;55(3):1160-3. doi: 10.1002/anie.201507269. Epub 2015 Dec 4.

PMID:
26634801
28.

Ubiquitylation of CD98 limits cell proliferation and clonal expansion.

Ablack JN, Metz PJ, Chang JT, Cantor JM, Ginsberg MH.

J Cell Sci. 2015 Dec 1;128(23):4273-8. doi: 10.1242/jcs.178129. Epub 2015 Oct 22.

29.

Asymmetric Cell Division in T Lymphocyte Fate Diversification.

Arsenio J, Metz PJ, Chang JT.

Trends Immunol. 2015 Nov;36(11):670-683. doi: 10.1016/j.it.2015.09.004. Epub 2015 Oct 20. Review.

30.

Spectroscopy and laser operation of Sm(3+)-doped lithium lutetium tetrafluoride (LiLuF(4)) and strontium hexaaluminate (SrAl(12)O(19)).

Marzahl DT, Metz PW, Kränkel C, Huber G.

Opt Express. 2015 Aug 10;23(16):21118-27. doi: 10.1364/OE.23.021118.

PMID:
26367962
31.

Reply to: "CD8(+) T cell diversification by asymmetric cell division".

Arsenio J, Kakaradov B, Metz PJ, Yeo GW, Chang JT.

Nat Immunol. 2015 Sep;16(9):893-4. doi: 10.1038/ni.3234. No abstract available.

32.

DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.

Grünvogel O, Esser-Nobis K, Reustle A, Schult P, Müller B, Metz P, Trippler M, Windisch MP, Frese M, Binder M, Fackler O, Bartenschlager R, Ruggieri A, Lohmann V.

J Virol. 2015 Oct;89(20):10548-68. doi: 10.1128/JVI.01297-15. Epub 2015 Aug 12.

33.

Therapeutic effect of methotrexate encapsulated in cationic liposomes (EndoMTX) in comparison to free methotrexate in an antigen-induced arthritis study in vivo.

Gottschalk O, Metz P, Dao Trong ML, Altenberger S, Jansson V, Mutschler W, Schmitt-Sody M.

Scand J Rheumatol. 2015;44(6):456-63. doi: 10.3109/03009742.2015.1030448. Epub 2015 Jun 26.

PMID:
26114440
34.

Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62.

Metz P, Chiramel A, Chatel-Chaix L, Alvisi G, Bankhead P, Mora-Rodriguez R, Long G, Hamacher-Brady A, Brady NR, Bartenschlager R.

J Virol. 2015 Aug;89(15):8026-41.

35.

Simultaneous and accurate measurement of the dielectric constant at many frequencies spanning a wide range.

Pérez-Aparicio R, Crauste-Thibierge C, Cottinet D, Tanase M, Metz P, Bellon L, Naert A, Ciliberto S.

Rev Sci Instrum. 2015 Apr;86(4):044702. doi: 10.1063/1.4916260.

PMID:
25933875
36.

Deep red diode-pumped Pr³⁺:KY₃F₁₀ continuous-wave laser.

Sottile A, Metz PW.

Opt Lett. 2015 May 1;40(9):1992-5. doi: 10.1364/OL.40.001992.

PMID:
25927766
37.

Regulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι.

Metz PJ, Arsenio J, Kakaradov B, Kim SH, Remedios KA, Oakley K, Akimoto K, Ohno S, Yeo GW, Chang JT.

J Immunol. 2015 Mar 1;194(5):2249-59. doi: 10.4049/jimmunol.1401652. Epub 2015 Jan 23.

38.

Identification of HNRNPK as regulator of hepatitis C virus particle production.

Poenisch M, Metz P, Blankenburg H, Ruggieri A, Lee JY, Rupp D, Rebhan I, Diederich K, Kaderali L, Domingues FS, Albrecht M, Lohmann V, Erfle H, Bartenschlager R.

PLoS Pathog. 2015 Jan 8;11(1):e1004573. doi: 10.1371/journal.ppat.1004573. eCollection 2015 Jan.

39.

Insights into the pamamycin biosynthesis.

Rebets Y, Brötz E, Manderscheid N, Tokovenko B, Myronovskyi M, Metz P, Petzke L, Luzhetskyy A.

Angew Chem Int Ed Engl. 2015 Feb 9;54(7):2280-4. doi: 10.1002/anie.201408901. Epub 2014 Dec 23.

PMID:
25537663
40.

SESAM mode-locked red praseodymium laser.

Gaponenko M, Metz PW, Härkönen A, Heuer A, Leinonen T, Guina M, Südmeyer T, Huber G, Kränkel C.

Opt Lett. 2014 Dec 15;39(24):6939-41. doi: 10.1364/OL.39.006939.

PMID:
25503035
41.

Yellow laser performance of Dy³⁺ in co-doped Dy,Tb:LiLuF₄.

Bolognesi G, Parisi D, Calonico D, Costanzo GA, Levi F, Metz PW, Kränkel C, Huber G, Tonelli M.

Opt Lett. 2014 Dec 1;39(23):6628-31. doi: 10.1364/OL.39.006628.

PMID:
25490638
42.

Continuous-wave Pr³⁺:BaY₂F₈ and Pr³⁺:LiYF₄ lasers in the cyan-blue spectral region.

Metz PW, Hasse K, Parisi D, Hansen NO, Kränkel C, Tonelli M, Huber G.

Opt Lett. 2014 Sep 1;39(17):5158-61. doi: 10.1364/OL.39.005158.

PMID:
25166098
43.

High-power red, orange, and green Pr³⁺:LiYF₄ lasers.

Metz PW, Reichert F, Moglia F, Müller S, Marzahl DT, Kränkel C, Huber G.

Opt Lett. 2014 Jun 1;39(11):3193-6. doi: 10.1364/OL.39.003193.

PMID:
24876010
44.

Simvastatin reduces leucocyte- and platelet-endothelial cell interaction in murine antigen-induced arthritis in vivo.

Gottschalk O, Dao Trong ML, Metz P, Wallmichrath J, Piltz S, Jauch KW, Jansson V, Schmitt-Sody M.

Scand J Rheumatol. 2014;43(5):356-63. doi: 10.3109/03009742.2013.879606. Epub 2014 May 14.

PMID:
24825390
45.

[3D-imaging and analysis for plastic surgery by smartphone and tablet: an alternative to professional systems?].

Koban KC, Leitsch S, Holzbach T, Volkmer E, Metz PM, Giunta RE.

Handchir Mikrochir Plast Chir. 2014 Apr;46(2):97-104. doi: 10.1055/s-0034-1371822. Epub 2014 Apr 28. German.

PMID:
24777459
46.

Thin-disk laser operation of Pr³⁺,Mg²⁺:SrAl₁₂O₁₉.

Voss A, Reichert F, Metz PW, Marzahl DT, Kränkel C, Huber G, Graf T.

Opt Lett. 2014 Mar 1;39(5):1322-5. doi: 10.1364/OL.39.001322.

PMID:
24690737
47.

Highly efficient continuous wave blue second-harmonic generation in fs-laser written periodically poled Rb:KTiOPO₄ waveguides.

Müller S, Calmano T, Metz PW, Kränkel C, Canalias C, Liljestrand C, Laurell F, Huber G.

Opt Lett. 2014 Mar 1;39(5):1274-7. doi: 10.1364/OL.39.001274.

PMID:
24690725
48.

Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses.

Arsenio J, Kakaradov B, Metz PJ, Kim SH, Yeo GW, Chang JT.

Nat Immunol. 2014 Apr;15(4):365-372. doi: 10.1038/ni.2842. Epub 2014 Mar 2.

49.

Wide wavelength tunability and green laser operation of diode-pumped Pr3+:KY3F10.

Metz PW, Müller S, Reichert F, Marzahl DT, Moglia F, Kränkel C, Huber G.

Opt Express. 2013 Dec 16;21(25):31274-81. doi: 10.1364/OE.21.031274.

PMID:
24514701
50.

Compact, transmissive two-dimensional spatial disperser design with application in simultaneous endoscopic imaging and laser microsurgery.

Metz P, Adam J, Gerken M, Jalali B.

Appl Opt. 2014 Jan 20;53(3):376-82. doi: 10.1364/AO.53.000376.

PMID:
24514122

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