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Items: 6

1.

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, Frohberger SJ, Sjoberg H, Pionnier N, Murphy E, Archer J, Steven A, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Kwenti TDB, Woods AK, Joseph SB, Hull MV, Xiong W, Kuhen KL, Taylor MJ, Wanji S, Turner JD, Hübner MP, Hoerauf A, Chatterjee AK, Roland J, Tremblay MS, Schultz PG, Sullivan W, Chu XJ, Petrassi HM, McNamara CW.

Sci Transl Med. 2019 May 8;11(491). pii: eaav3523. doi: 10.1126/scitranslmed.aav3523.

PMID:
31068442
2.

Mouse models of Loa loa.

Pionnier NP, Sjoberg H, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Tayong DB, Taylor MJ, Wanji S, Turner JD.

Nat Commun. 2019 Mar 29;10(1):1429. doi: 10.1038/s41467-019-09442-0.

3.

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau2086. doi: 10.1126/scitranslmed.aau2086.

PMID:
30867321
4.

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models.

Sjoberg HT, Pionnier N, Aljayyoussi G, Metuge HM, Njouendou AJ, Chunda VC, Fombad FF, Tayong DB, Gandjui NVT, Akumtoh DN, Chounna PWN, Ndzeshang BL, Lachaud S, Tekle F, Quirynen L, Engelen M, Baeten B, Steven A, Ward SA, Taylor MJ, Wanji S, Turner JD.

PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0006356. doi: 10.1371/journal.pntd.0006356. eCollection 2019 Jan.

5.

Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents.

Fombad FF, Njouendou AJ, Ndongmo PC, Ritter M, Chunda VC, Metuge HM, Gandjui NVT, Enyong P, Njiokou F, Hoerauf A, Mackenzie CD, Wanji S.

Parasit Vectors. 2019 Jan 8;12(1):14. doi: 10.1186/s13071-018-3282-x.

6.

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis.

Halliday A, Guimaraes AF, Tyrer HE, Metuge HM, Patrick CN, Arnaud KO, Kwenti TD, Forsbrook G, Steven A, Cook D, Enyong P, Wanji S, Taylor MJ, Turner JD.

Parasit Vectors. 2014 Oct 24;7:472. doi: 10.1186/s13071-014-0472-z.

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