Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 61


Ethanol Conditioned Taste Aversion in High Drinking in the Dark Mice.

Crabbe JC, Metten P, Savarese AM, Ozburn AR, Schlumbohm JP, Spence SE, Hack WR.

Brain Sci. 2019 Jan 1;9(1). pii: E2. doi: 10.3390/brainsci9010002.


Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs.

Iancu OD, Colville AM, Wilmot B, Searles R, Darakjian P, Zheng C, McWeeney S, Kawane S, Crabbe JC, Metten P, Oberbeck D, Hitzemann R.

Alcohol Clin Exp Res. 2018 May 22. doi: 10.1111/acer.13777. [Epub ahead of print]


An alcohol withdrawal test battery measuring multiple behavioral symptoms in mice.

Metten P, Schlumbohm JP, Huang LC, Greenberg GD, Hack WR, Spence SE, Crabbe JC.

Alcohol. 2018 May;68:19-35. doi: 10.1016/j.alcohol.2017.08.014. Epub 2017 Sep 6.


Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice.

Ferguson LB, Ozburn AR, Ponomarev I, Metten P, Reilly M, Crabbe JC, Harris RA, Mayfield RD.

Neuropsychopharmacology. 2018 May;43(6):1257-1266. doi: 10.1038/npp.2017.301. Epub 2017 Dec 18.


High Drinking in the Dark (HDID) mice are sensitive to the effects of some clinically relevant drugs to reduce binge-like drinking.

Crabbe JC, Ozburn AR, Metten P, Barkley-Levenson A, Schlumbohm JP, Spence SE, Hack WR, Huang LC.

Pharmacol Biochem Behav. 2017 Sep;160:55-62. doi: 10.1016/j.pbb.2017.08.002. Epub 2017 Aug 5.


Alignment of the transcriptome with individual variation in animals selectively bred for High Drinking-In-the-Dark (HDID).

Hitzemann R, Oberbeck D, Iancu O, Darakjian P, McWeeney S, Spence S, Schlumbohm J, Metten P, Crabbe J.

Alcohol. 2017 May;60:115-120. doi: 10.1016/j.alcohol.2017.02.176. Epub 2017 Apr 12.


Fear conditioning in mouse lines genetically selected for binge-like ethanol drinking.

Crabbe JC, Schlumbohm JP, Hack W, Barkley-Levenson AM, Metten P, Lattal KM.

Alcohol. 2016 May;52:25-32. doi: 10.1016/j.alcohol.2016.01.004. Epub 2016 Feb 17.


Nest building is a novel method for indexing severity of alcohol withdrawal in mice.

Greenberg GD, Huang LC, Spence SE, Schlumbohm JP, Metten P, Ozburn AR, Crabbe JC.

Behav Brain Res. 2016 Apr 1;302:182-90. doi: 10.1016/j.bbr.2016.01.023. Epub 2016 Jan 12.


Dual-trait selection for ethanol consumption and withdrawal: genetic and transcriptional network effects.

Metten P, Iancu OD, Spence SE, Walter NA, Oberbeck D, Harrington CA, Colville A, McWeeney S, Phillips TJ, Buck KJ, Crabbe JC, Belknap JK, Hitzemann RJ.

Alcohol Clin Exp Res. 2014 Dec;38(12):2915-24. doi: 10.1111/acer.12574.


Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.

Bubier JA, Jay JJ, Baker CL, Bergeson SE, Ohno H, Metten P, Crabbe JC, Chesler EJ.

Genetics. 2014 Aug;197(4):1377-93. doi: 10.1534/genetics.114.166165. Epub 2014 Jun 11.


Genetic relationship between predisposition for binge alcohol consumption and blunted sensitivity to adverse effects of alcohol in mice.

Fritz BM, Cordero KA, Barkley-Levenson AM, Metten P, Crabbe JC, Boehm SL 2nd.

Alcohol Clin Exp Res. 2014 May;38(5):1284-92. doi: 10.1111/acer.12385. Epub 2014 Feb 25.


Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice.

Crabbe JC, Metten P, Belknap JK, Spence SE, Cameron AJ, Schlumbohm JP, Huang LC, Barkley-Levenson AM, Ford MM, Phillips TJ.

Genes Brain Behav. 2014 Feb;13(2):236-46. doi: 10.1111/gbb.12105. Epub 2013 Dec 6.


Ethanol drinking in withdrawal seizure-prone and -resistant selected mouse lines.

Crabbe JC, Spence SE, Huang LC, Cameron AJ, Schlumbohm JP, Barkley-Levenson AM, Metten P.

Alcohol. 2013 Aug;47(5):381-9. doi: 10.1016/j.alcohol.2013.05.002. Erratum in: Alcohol. 2013 Dec;47(8):651.


Selection for drinking in the dark alters brain gene coexpression networks.

Iancu OD, Oberbeck D, Darakjian P, Metten P, McWeeney S, Crabbe JC, Hitzemann R.

Alcohol Clin Exp Res. 2013 Aug;37(8):1295-303. doi: 10.1111/acer.12100. Epub 2013 Mar 29.


Ethanol Withdrawal-Associated Drinking and Drinking in the Dark: Common and Discrete Genetic Contributions.

Crabbe JC, Metten P, Huang LC, Schlumbohm JP, Spence SE, Barkley-Levenson AM, Finn DA, Rhodes JS, Cameron AJ.

Addict Genet. 2012 Oct 19;1:3-11.


Intermittent availability of ethanol does not always lead to elevated drinking in mice.

Crabbe JC, Harkness JH, Spence SE, Huang LC, Metten P.

Alcohol Alcohol. 2012 Sep-Oct;47(5):509-17. doi: 10.1093/alcalc/ags067. Epub 2012 Jun 19.


Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.

Cozzoli DK, Courson J, Caruana AL, Miller BW, Greentree DI, Thompson AB, Wroten MG, Zhang PW, Xiao B, Hu JH, Klugmann M, Metten P, Worley PF, Crabbe JC, Szumlinski KK.

Alcohol Clin Exp Res. 2012 Sep;36(9):1623-33. doi: 10.1111/j.1530-0277.2012.01776.x. Epub 2012 Mar 20.


Ethanol sensitivity in high drinking in the dark selectively bred mice.

Crabbe JC, Kruse LC, Colville AM, Cameron AJ, Spence SE, Schlumbohm JP, Huang LC, Metten P.

Alcohol Clin Exp Res. 2012 Jul;36(7):1162-70. doi: 10.1111/j.1530-0277.2012.01735.x. Epub 2012 Feb 8.


Ethanol tolerance and withdrawal severity in high drinking in the dark selectively bred mice.

Crabbe JC, Colville AM, Kruse LC, Cameron AJ, Spence SE, Schlumbohm JP, Huang LC, Metten P.

Alcohol Clin Exp Res. 2012 Jul;36(7):1152-61. doi: 10.1111/j.1530-0277.2011.01715.x. Epub 2012 Feb 6.


Ethanol withdrawal-induced motor impairment in mice.

Philibin SD, Cameron AJ, Schlumbohm JP, Metten P, Crabbe JC.

Psychopharmacology (Berl). 2012 Mar;220(2):367-78. doi: 10.1007/s00213-011-2483-1. Epub 2011 Sep 24.


Limited access ethanol drinking in the dark in adolescent and adult mice.

Metten P, Brown LL, Crabbe JC.

Pharmacol Biochem Behav. 2011 Apr;98(2):279-85. doi: 10.1016/j.pbb.2011.01.003. Epub 2011 Jan 14.


Alcohol preference drinking in a mouse line selectively bred for high drinking in the dark.

Crabbe JC, Spence SE, Brown LL, Metten P.

Alcohol. 2011 Aug;45(5):427-40. doi: 10.1016/j.alcohol.2010.12.001. Epub 2010 Dec 30.


Withdrawal severity after chronic intermittent ethanol in inbred mouse strains.

Metten P, Sorensen ML, Cameron AJ, Yu CH, Crabbe JC.

Alcohol Clin Exp Res. 2010 Sep 1;34(9):1552-64. doi: 10.1111/j.1530-0277.2010.01240.x. Epub 2010 Jun 25.


Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism.

Cozzoli DK, Goulding SP, Zhang PW, Xiao B, Hu JH, Ary AW, Obara I, Rahn A, Abou-Ziab H, Tyrrel B, Marini C, Yoneyama N, Metten P, Snelling C, Dehoff MH, Crabbe JC, Finn DA, Klugmann M, Worley PF, Szumlinski KK.

J Neurosci. 2009 Jul 8;29(27):8655-68. doi: 10.1523/JNEUROSCI.5900-08.2009.


A line of mice selected for high blood ethanol concentrations shows drinking in the dark to intoxication.

Crabbe JC, Metten P, Rhodes JS, Yu CH, Brown LL, Phillips TJ, Finn DA.

Biol Psychiatry. 2009 Apr 15;65(8):662-70. doi: 10.1016/j.biopsych.2008.11.002. Epub 2008 Dec 18.


Calibration of rotational acceleration for the rotarod test of rodent motor coordination.

Bohlen M, Cameron A, Metten P, Crabbe JC, Wahlsten D.

J Neurosci Methods. 2009 Mar 30;178(1):10-4. doi: 10.1016/j.jneumeth.2008.11.001. Epub 2008 Nov 12.


Genetic correlates of morphine withdrawal in 14 inbred mouse strains.

Metten P, Crabbe JC, Belknap JK.

Drug Alcohol Depend. 2009 Jan 1;99(1-3):123-31. doi: 10.1016/j.drugalcdep.2008.07.006. Epub 2008 Sep 6.


Multivariate analyses reveal common and drug-specific genetic influences on responses to four drugs of abuse.

Belknap JK, Metten P, Beckley EH, Crabbe JC.

Trends Pharmacol Sci. 2008 Nov;29(11):537-43. doi: 10.1016/ Epub 2008 Sep 4. Review.


Motor impairment: a new ethanol withdrawal phenotype in mice.

Philibin SD, Cameron AJ, Metten P, Crabbe JC.

Behav Pharmacol. 2008 Sep;19(5-6):604-14. doi: 10.1097/FBP.0b013e32830ded27.


Use of a novel mouse genotype to model acute benzodiazepine withdrawal.

Metten P, Buck KJ, Merrill CM, Roberts AJ, Yu CH, Crabbe JC.

Behav Genet. 2007 Jan;37(1):160-70. Epub 2006 Aug 5.


Effects of genetic and procedural variation on measurement of alcohol sensitivity in mouse inbred strains.

Crabbe JC, Metten P, Ponomarev I, Prescott CA, Wahlsten D.

Behav Genet. 2006 Jul;36(4):536-52. Epub 2006 Apr 18.


Fine mapping of a sedative-hypnotic drug withdrawal locus on mouse chromosome 11.

Hood HM, Metten P, Crabbe JC, Buck KJ.

Genes Brain Behav. 2006 Feb;5(1):1-10.


Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice.

Blednov YA, Metten P, Finn DA, Rhodes JS, Bergeson SE, Harris RA, Crabbe JC.

Alcohol Clin Exp Res. 2005 Nov;29(11):1949-58.


Alcohol withdrawal severity in inbred mouse (Mus musculus) strains.

Metten P, Crabbe JC.

Behav Neurosci. 2005 Aug;119(4):911-25.


Scheduled access to ethanol results in motor impairment and tolerance in female C57BL/6J mice.

Cronise K, Finn DA, Metten P, Crabbe JC.

Pharmacol Biochem Behav. 2005 Aug;81(4):943-53.


An analysis of the genetics of alcohol intoxication in inbred mice.

Crabbe JC, Metten P, Cameron AJ, Wahlsten D.

Neurosci Biobehav Rev. 2005 Jan;28(8):785-802. Review.


Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs.

Kliethermes CL, Metten P, Belknap JK, Buck KJ, Crabbe JC.

Brain Res. 2004 May 29;1009(1-2):17-25.


Observer-rated ataxia: rating scales for assessment of genetic differences in ethanol-induced intoxication in mice.

Metten P, Best KL, Cameron AJ, Saultz AB, Zuraw JM, Yu CH, Wahlsten D, Crabbe JC.

J Appl Physiol (1985). 2004 Jul;97(1):360-8. Epub 2004 Mar 19.


Potential pleiotropic effects of Mpdz on vulnerability to seizures.

Fehr C, Shirley RL, Metten P, Kosobud AE, Belknap JK, Crabbe JC, Buck KJ.

Genes Brain Behav. 2004 Feb;3(1):8-19.


Strain differences in three measures of ethanol intoxication in mice: the screen, dowel and grip strength tests.

Crabbe JC, Cotnam CJ, Cameron AJ, Schlumbohm JP, Rhodes JS, Metten P, Wahlsten D.

Genes Brain Behav. 2003 Aug;2(4):201-13. Erratum in: Genes Brain Behav. 2004 Aug;3(4):252.


Chromosomal loci influencing chronic alcohol withdrawal severity.

Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK.

Mamm Genome. 2003 Jul;14(7):454-63.


Genotypic differences in ethanol sensitivity in two tests of motor incoordination.

Crabbe JC, Metten P, Yu CH, Schlumbohm JP, Cameron AJ, Wahlsten D.

J Appl Physiol (1985). 2003 Oct;95(4):1338-51. Epub 2003 Apr 18.


In search of a better mouse test.

Wahlsten D, Rustay NR, Metten P, Crabbe JC.

Trends Neurosci. 2003 Mar;26(3):132-6. Review.


Different data from different labs: lessons from studies of gene-environment interaction.

Wahlsten D, Metten P, Phillips TJ, Boehm SL 2nd, Burkhart-Kasch S, Dorow J, Doerksen S, Downing C, Fogarty J, Rodd-Henricks K, Hen R, McKinnon CS, Merrill CM, Nolte C, Schalomon M, Schlumbohm JP, Sibert JR, Wenger CD, Dudek BC, Crabbe JC.

J Neurobiol. 2003 Jan;54(1):283-311. Review.


Genetic determinants of sensitivity to pentobarbital in inbred mice.

Crabbe JC, Metten P, Gallaher EJ, Belknap JK.

Psychopharmacology (Berl). 2002 Jun;161(4):408-16. Epub 2002 Apr 24.


Mapping of quantitative trait loci underlying ethanol metabolism in BXD recombinant inbred mouse strains.

Grisel JE, Metten P, Wenger CD, Merrill CM, Crabbe JC.

Alcohol Clin Exp Res. 2002 May;26(5):610-6.


Mapping murine loci for physical dependence on ethanol.

Buck KJ, Rademacher BS, Metten P, Crabbe JC.

Psychopharmacology (Berl). 2002 Apr;160(4):398-407. Epub 2002 Feb 15.


Protein kinase C epsilon mediates up-regulation of N-type calcium channels by ethanol.

McMahon T, Andersen R, Metten P, Crabbe JC, Messing RO.

Mol Pharmacol. 2000 Jan;57(1):53-8.


Supplemental Content

Loading ...
Support Center