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Items: 11

1.

Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65.

Delaney CE, Methot SP, Guidi M, Katic I, Gasser SM, Padeken J.

J Cell Biol. 2019 Feb 8. pii: jcb.201811038. doi: 10.1083/jcb.201811038. [Epub ahead of print]

PMID:
30737265
2.

PRMT5 is essential for B cell development and germinal center dynamics.

Litzler LC, Zahn A, Meli AP, Hébert S, Patenaude AM, Methot SP, Sprumont A, Bois T, Kitamura D, Costantino S, King IL, Kleinman CL, Richard S, Di Noia JM.

Nat Commun. 2019 Jan 3;10(1):22. doi: 10.1038/s41467-018-07884-6.

3.

A licensing step links AID to transcription elongation for mutagenesis in B cells.

Methot SP, Litzler LC, Subramani PG, Eranki AK, Fifield H, Patenaude AM, Gilmore JC, Santiago GE, Bagci H, Côté JF, Larijani M, Verdun RE, Di Noia JM.

Nat Commun. 2018 Mar 28;9(1):1248. doi: 10.1038/s41467-018-03387-6.

4.

Molecular Mechanisms of Somatic Hypermutation and Class Switch Recombination.

Methot SP, Di Noia JM.

Adv Immunol. 2017;133:37-87. doi: 10.1016/bs.ai.2016.11.002. Epub 2016 Dec 22. Review.

PMID:
28215280
5.

Pharmacological manipulation of AID.

Methot SP, Di Noia JM.

Oncotarget. 2015 Sep 29;6(29):26550-1. doi: 10.18632/oncotarget.5269. No abstract available.

6.

Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.

Methot SP, Litzler LC, Trajtenberg F, Zahn A, Robert F, Pelletier J, Buschiazzo A, Magor BG, Di Noia JM.

J Exp Med. 2015 Apr 6;212(4):581-96. doi: 10.1084/jem.20141157. Epub 2015 Mar 30.

7.

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.

Zahn A, Eranki AK, Patenaude AM, Methot SP, Fifield H, Cortizas EM, Foster P, Imai K, Durandy A, Larijani M, Verdun RE, Di Noia JM.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E988-97. doi: 10.1073/pnas.1320486111. Epub 2014 Mar 3.

8.

Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin.

Baker JH, Kyle AH, Bartels KL, Methot SP, Flanagan EJ, Balbirnie A, Cran JD, Minchinton AI.

PLoS One. 2013 Oct 28;8(10):e76832. doi: 10.1371/journal.pone.0076832. eCollection 2013.

9.

A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.

Hu Y, Ericsson I, Torseth K, Methot SP, Sundheim O, Liabakk NB, Slupphaug G, Di Noia JM, Krokan HE, Kavli B.

J Mol Biol. 2013 Jan 23;425(2):424-43. doi: 10.1016/j.jmb.2012.11.026. Epub 2012 Nov 23.

PMID:
23183374
10.

Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1.

Orthwein A, Zahn A, Methot SP, Godin D, Conticello SG, Terada K, Di Noia JM.

EMBO J. 2012 Feb 1;31(3):679-91. doi: 10.1038/emboj.2011.417. Epub 2011 Nov 15.

11.

Guanine-rich RNAs and DNAs that bind heme robustly catalyze oxygen transfer reactions.

Poon LC, Methot SP, Morabi-Pazooki W, Pio F, Bennet AJ, Sen D.

J Am Chem Soc. 2011 Feb 16;133(6):1877-84. doi: 10.1021/ja108571a. Epub 2011 Jan 25.

PMID:
21265562

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