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Items: 1 to 50 of 349

1.

Associations of MAP2K3 Gene Variants With Superior Memory in SuperAgers.

Huentelman MJ, Piras IS, Siniard AL, De Both MD, Richholt RF, Balak CD, Jamshidi P, Bigio EH, Weintraub S, Loyer ET, Mesulam MM, Geula C, Rogalski EJ.

Front Aging Neurosci. 2018 May 29;10:155. doi: 10.3389/fnagi.2018.00155. eCollection 2018.

2.

The cholinergic system in the pathophysiology and treatment of Alzheimer's disease.

Hampel H, Mesulam MM, Cuello AC, Farlow MR, Giacobini E, Grossberg GT, Khachaturian AS, Vergallo A, Cavedo E, Snyder PJ, Khachaturian ZS.

Brain. 2018 Jul 1;141(7):1917-1933. doi: 10.1093/brain/awy132.

PMID:
29850777
3.

A nonverbal route to conceptual knowledge involving the right anterior temporal lobe.

Hurley RS, Mesulam MM, Sridhar J, Rogalski EJ, Thompson CK.

Neuropsychologia. 2018 May 23;117:92-101. doi: 10.1016/j.neuropsychologia.2018.05.019. [Epub ahead of print]

PMID:
29802865
4.

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Pottier C, Zhou X, Perkerson RB 3rd, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sánchez-Valle R, Antonell A, Lladó A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D, Graff C, Öijerstedt L, Troakes C, Al-Sarraj S, Cruchaga C, Cairns NJ, Rohrer JD, Halliday GM, Kwok JB, van Swieten JC, White CL 3rd, Ghetti B, Murell JR, Mackenzie IRA, Hsiung GR, Borroni B, Rossi G, Tagliavini F, Wszolek ZK, Petersen RC, Bigio EH, Grossman M, Van Deerlin VM, Seeley WW, Miller BL, Graff-Radford NR, Boeve BF, Dickson DW, Biernacka JM, Rademakers R.

Lancet Neurol. 2018 Jun;17(6):548-558. doi: 10.1016/S1474-4422(18)30126-1. Epub 2018 Apr 30.

PMID:
29724592
5.

Prominent microglial activation in cortical white matter is selectively associated with cortical atrophy in primary progressive aphasia.

Ohm DT, Kim G, Gefen T, Rademaker A, Weintraub S, Bigio EH, Mesulam MM, Rogalski E, Geula C.

Neuropathol Appl Neurobiol. 2018 Apr 21. doi: 10.1111/nan.12494. [Epub ahead of print]

PMID:
29679378
6.

Atrophy and microglial distribution in primary progressive aphasia with transactive response DNA-binding protein-43 kDa.

Kim G, Bolbolan K, Gefen T, Weintraub S, Bigio EH, Rogalski E, Mesulam MM, Geula C.

Ann Neurol. 2018 Apr 17. doi: 10.1002/ana.25240. [Epub ahead of print]

PMID:
29665116
7.

Combined Pathologies in FTLD-TDP Types A and C.

Gefen T, Ahmadian SS, Mao Q, Kim G, Seckin M, Bonakdarpour B, Ramos EM, Coppola G, Rademakers R, Rogalski E, Rademaker A, Weintraub S, Mesulam MM, Geula C, Bigio EH.

J Neuropathol Exp Neurol. 2018 May 1;77(5):405-412. doi: 10.1093/jnen/nly018.

PMID:
29584904
8.

Semantic Typicality Effects in Primary Progressive Aphasia.

Riley EA, Barbieri E, Weintraub S, Mesulam MM, Thompson CK.

Am J Alzheimers Dis Other Demen. 2018 Aug;33(5):292-300. doi: 10.1177/1533317518762443. Epub 2018 Mar 16.

PMID:
29544341
9.

Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases.

Rogalski E, Gefen T, Mao Q, Connelly M, Weintraub S, Geula C, Bigio EH, Mesulam MM.

Hippocampus. 2018 Jan 17. doi: 10.1002/hipo.22828. [Epub ahead of print]

PMID:
29341318
10.

Asymmetric TDP pathology in primary progressive aphasia with right hemisphere language dominance.

Kim G, Vahedi S, Gefen T, Weintraub S, Bigio EH, Mesulam MM, Geula C.

Neurology. 2018 Jan 30;90(5):e396-e403. doi: 10.1212/WNL.0000000000004891. Epub 2018 Jan 5.

PMID:
29305438
11.

Von Economo neurons of the anterior cingulate across the lifespan and in Alzheimer's disease.

Gefen T, Papastefan ST, Rezvanian A, Bigio EH, Weintraub S, Rogalski E, Mesulam MM, Geula C.

Cortex. 2018 Feb;99:69-77. doi: 10.1016/j.cortex.2017.10.015. Epub 2017 Nov 8.

PMID:
29175073
12.

Psychological well-being in elderly adults with extraordinary episodic memory.

Cook Maher A, Kielb S, Loyer E, Connelley M, Rademaker A, Mesulam MM, Weintraub S, McAdams D, Logan R, Rogalski E.

PLoS One. 2017 Oct 23;12(10):e0186413. doi: 10.1371/journal.pone.0186413. eCollection 2017.

13.

Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration.

Mao Q, Wang D, Li Y, Kohler M, Wilson J, Parton Z, Shmaltsuyeva B, Gursel D, Rademakers R, Weintraub S, Mesulam MM, Xia H, Bigio EH.

J Neuropathol Exp Neurol. 2017 Nov 1;76(11):957-968. doi: 10.1093/jnen/nlx085.

PMID:
29044416
14.

WITHDRAWN: Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research.

Hampel H, Mesulam MM, Cuello AC, Khachaturian AS, Farlow MR, Snyder PJ, Giacobini E, Khachaturian ZS; Cholinergic System Working Group.

Alzheimers Dement. 2017 Oct 10. pii: S1552-5260(17)33719-6. doi: 10.1016/j.jalz.2017.08.016. [Epub ahead of print]

PMID:
29028480
15.

Evidence for an early innate immune response in the motor cortex of ALS.

Jara JH, Genç B, Stanford MJ, Pytel P, Roos RP, Weintraub S, Mesulam MM, Bigio EH, Miller RJ, Özdinler PH.

J Neuroinflammation. 2017 Jun 26;14(1):129. doi: 10.1186/s12974-017-0896-4.

16.

Communication Bridge: A pilot feasibility study of Internet-based speech-language therapy for individuals with progressive aphasia.

Rogalski EJ, Saxon M, McKenna H, Wieneke C, Rademaker A, Corden ME, Borio K, Mesulam MM, Khayum B.

Alzheimers Dement (N Y). 2016 Nov;2(4):213-221. doi: 10.1016/j.trci.2016.08.005.

17.

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.

Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ.

Sci Transl Med. 2017 Apr 12;9(385). pii: eaah5642. doi: 10.1126/scitranslmed.aah5642.

18.

Selective verbal recognition memory impairments are associated with atrophy of the language network in non-semantic variants of primary progressive aphasia.

Nilakantan AS, Voss JL, Weintraub S, Mesulam MM, Rogalski EJ.

Neuropsychologia. 2017 Jun;100:10-17. doi: 10.1016/j.neuropsychologia.2017.04.006. Epub 2017 Apr 6.

19.

Rates of Cortical Atrophy in Adults 80 Years and Older With Superior vs Average Episodic Memory.

Cook AH, Sridhar J, Ohm D, Rademaker A, Mesulam MM, Weintraub S, Rogalski E.

JAMA. 2017 Apr 4;317(13):1373-1375. doi: 10.1001/jama.2017.0627. No abstract available. Erratum in: JAMA. 2017 May 9;317(18):1912.

20.

Proof of concept demonstration of optimal composite MRI endpoints for clinical trials.

Edland SD, Ard MC, Sridhar J, Cobia D, Martersteck A, Mesulam MM, Rogalski EJ.

Alzheimers Dement (N Y). 2016 Sep;2(3):177-181. doi: 10.1016/j.trci.2016.05.002.

21.

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction.

Lopez A, Lee SE, Wojta K, Ramos EM, Klein E, Chen J, Boxer AL, Gorno-Tempini ML, Geschwind DH, Schlotawa L, Ogryzko NV, Bigio EH, Rogalski E, Weintraub S, Mesulam MM; Tauopathy Genetics Consortium, Fleming A, Coppola G, Miller BL, Rubinsztein DC.

Brain. 2017 Apr 1;140(4):1128-1146. doi: 10.1093/brain/awx005.

22.

Variations in Acetylcholinesterase Activity within Human Cortical Pyramidal Neurons Across Age and Cognitive Trajectories.

Janeczek M, Gefen T, Samimi M, Kim G, Weintraub S, Bigio E, Rogalski E, Mesulam MM, Geula C.

Cereb Cortex. 2018 Apr 1;28(4):1329-1337. doi: 10.1093/cercor/bhx047.

PMID:
28334147
23.

Functional Connectivity is Reduced in Early-stage Primary Progressive Aphasia When Atrophy is not Prominent.

Bonakdarpour B, Rogalski EJ, Wang A, Sridhar J, Mesulam MM, Hurley RS.

Alzheimer Dis Assoc Disord. 2017 Apr-Jun;31(2):101-106. doi: 10.1097/WAD.0000000000000193.

24.

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia.

Oboudiyat C, Gefen T, Varelas E, Weintraub S, Rogalski E, Bigio EH, Mesulam MM.

Alzheimers Dement. 2017 May;13(5):598-601. doi: 10.1016/j.jalz.2017.01.006. Epub 2017 Feb 11.

25.

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS.

Genç B, Jara JH, Lagrimas AK, Pytel P, Roos RP, Mesulam MM, Geula C, Bigio EH, Özdinler PH.

Sci Rep. 2017 Feb 6;7:41765. doi: 10.1038/srep41765.

26.

Case 1-2017. A 70-Year-Old Woman with Gradually Progressive Loss of Language.

Mesulam MM, Dickerson BC, Sherman JC, Hochberg D, Gonzalez RG, Johnson KA, Frosch MP.

N Engl J Med. 2017 Jan 12;376(2):158-167. doi: 10.1056/NEJMcpc1613459. No abstract available.

27.

Postmortem Adult Human Microglia Proliferate in Culture to High Passage and Maintain Their Response to Amyloid-β.

Guo L, Rezvanian A, Kukreja L, Hoveydai R, Bigio EH, Mesulam MM, El Khoury J, Geula C.

J Alzheimers Dis. 2016 Oct 4;54(3):1157-1167.

28.

Aphasic variant of Alzheimer disease: Clinical, anatomic, and genetic features.

Rogalski E, Sridhar J, Rader B, Martersteck A, Chen K, Cobia D, Thompson CK, Weintraub S, Bigio EH, Mesulam MM.

Neurology. 2016 Sep 27;87(13):1337-43. doi: 10.1212/WNL.0000000000003165. Epub 2016 Aug 26.

29.

Neuropathologic Associations of Learning and Memory in Primary Progressive Aphasia.

Kielb S, Cook A, Wieneke C, Rademaker A, Bigio EH, Mesulam MM, Rogalski E, Weintraub S.

JAMA Neurol. 2016 Jul 1;73(7):846-52. doi: 10.1001/jamaneurol.2016.0880.

30.

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.

Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesulam MM, Rademakers R, Mackenzie IR, Seeley WW, Karydas A, Miller BL, Borroni B, Ghidoni R, Farese RV Jr, Paz JT, Barres BA, Huang EJ.

Cell. 2016 May 5;165(4):921-35. doi: 10.1016/j.cell.2016.04.001. Epub 2016 Apr 21.

31.

Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?

Khachaturian ZS, Mesulam MM, Mohs RC, Khachaturian AS.

Alzheimers Dement. 2016 Mar;12(3):213-5. doi: 10.1016/j.jalz.2016.02.003. No abstract available.

PMID:
27012483
32.

Frontotemporal networks and behavioral symptoms in primary progressive aphasia.

D'Anna L, Mesulam MM, Thiebaut de Schotten M, Dell'Acqua F, Murphy D, Wieneke C, Martersteck A, Cobia D, Rogalski E, Catani M.

Neurology. 2016 Apr 12;86(15):1393-9. doi: 10.1212/WNL.0000000000002579. Epub 2016 Mar 18.

33.

Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database.

Ringman JM, Monsell S, Ng DW, Zhou Y, Nguyen A, Coppola G, Van Berlo V, Mendez MF, Tung S, Weintraub S, Mesulam MM, Bigio EH, Gitelman DR, Fisher-Hubbard AO, Albin RL, Vinters HV.

J Neuropathol Exp Neurol. 2016 Mar;75(3):284-90. doi: 10.1093/jnen/nlv028. Epub 2016 Feb 17.

34.

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions.

Kim G, Ahmadian SS, Peterson M, Parton Z, Memon R, Weintraub S, Rademaker A, Bigio E, Mesulam MM, Geula C.

Neurology. 2016 Feb 16;86(7):627-36. doi: 10.1212/WNL.0000000000002375. Epub 2016 Jan 20.

35.

Is in vivo amyloid distribution asymmetric in primary progressive aphasia?

Martersteck A, Murphy C, Rademaker A, Wieneke C, Weintraub S, Chen K, Mesulam MM, Rogalski E; Alzheimer's Disease Neuroimaging Initiative.

Ann Neurol. 2016 Mar;79(3):496-501. doi: 10.1002/ana.24566. Epub 2016 Feb 2.

36.

The Special Topics Section of Alzheimer's & Dementia.

Khachaturian ZS, Mesulam MM, Khachaturian AS, Mohs RC.

Alzheimers Dement. 2015 Nov;11(11):1261-4. doi: 10.1016/j.jalz.2015.10.002. No abstract available.

PMID:
26589667
37.

Am I looking at a cat or a dog? Gaze in the semantic variant of primary progressive aphasia is subject to excessive taxonomic capture.

Seckin M, Mesulam MM, Voss JL, Huang W, Rogalski EJ, Hurley RS.

J Neurolinguistics. 2016 Feb 1;37:68-81.

38.

Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease.

Ahmadian SS, Rezvanian A, Peterson M, Weintraub S, Bigio EH, Mesulam MM, Geula C.

Neurobiol Aging. 2015 Dec;36(12):3163-3170. doi: 10.1016/j.neurobiolaging.2015.09.001. Epub 2015 Sep 6.

39.

What do pauses in narrative production reveal about the nature of word retrieval deficits in PPA?

Mack JE, Chandler SD, Meltzer-Asscher A, Rogalski E, Weintraub S, Mesulam MM, Thompson CK.

Neuropsychologia. 2015 Oct;77:211-22. doi: 10.1016/j.neuropsychologia.2015.08.019. Epub 2015 Aug 20.

40.

Diffuse leukoencephalopathy with spheroids presenting as primary progressive aphasia.

Oboudiyat C, Bigio EH, Bonakdarpour B, Baker MC, Rademakers R, Weintraub S, Mesulam MM.

Neurology. 2015 Aug 18;85(7):652-3. doi: 10.1212/WNL.0000000000001851. Epub 2015 Jul 22. No abstract available.

41.

Fifty years of disconnexion syndromes and the Geschwind legacy.

Mesulam MM.

Brain. 2015 Sep;138(Pt 9):2791-9. doi: 10.1093/brain/awv198. Epub 2015 Jul 10. No abstract available.

PMID:
26163663
42.

Memory improvement via slow-oscillatory stimulation during sleep in older adults.

Westerberg CE, Florczak SM, Weintraub S, Mesulam MM, Marshall L, Zee PC, Paller KA.

Neurobiol Aging. 2015 Sep;36(9):2577-86. doi: 10.1016/j.neurobiolaging.2015.05.014. Epub 2015 Jun 3.

43.

The Wernicke conundrum and the anatomy of language comprehension in primary progressive aphasia.

Mesulam MM, Thompson CK, Weintraub S, Rogalski EJ.

Brain. 2015 Aug;138(Pt 8):2423-37. doi: 10.1093/brain/awv154. Epub 2015 Jun 25.

44.

Eye movements as probes of lexico-semantic processing in a patient with primary progressive aphasia.

Seckin M, Mesulam MM, Rademaker AW, Voss JL, Weintraub S, Rogalski EJ, Hurley RS.

Neurocase. 2016;22(1):65-75. doi: 10.1080/13554794.2015.1045523. Epub 2015 May 18.

45.

Hippocampal subfield surface deformity in non-semantic primary progressive aphasia.

Christensen A, Alpert K, Rogalski E, Cobia D, Rao J, Beg MF, Weintraub S, Mesulam MM, Wang L.

Alzheimers Dement (Amst). 2015 Mar 1;1(1):14-23.

46.

Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity.

Gefen T, Peterson M, Papastefan ST, Martersteck A, Whitney K, Rademaker A, Bigio EH, Weintraub S, Rogalski E, Mesulam MM, Geula C.

J Neurosci. 2015 Jan 28;35(4):1781-91. doi: 10.1523/JNEUROSCI.2998-14.2015.

47.

Association between the prevalence of learning disabilities and primary progressive aphasia.

Rogalski EJ, Rademaker A, Wieneke C, Bigio EH, Weintraub S, Mesulam MM.

JAMA Neurol. 2014 Dec;71(12):1576-7. doi: 10.1001/jamaneurol.2014.2805. No abstract available.

48.

A designated odor-language integration system in the human brain.

Olofsson JK, Hurley RS, Bowman NE, Bao X, Mesulam MM, Gottfried JA.

J Neurosci. 2014 Nov 5;34(45):14864-73. doi: 10.1523/JNEUROSCI.2247-14.2014.

49.

Asymmetric connectivity between the anterior temporal lobe and the language network.

Hurley RS, Bonakdarpour B, Wang X, Mesulam MM.

J Cogn Neurosci. 2015 Mar;27(3):464-73. doi: 10.1162/jocn_a_00722. Epub 2014 Sep 22.

50.

Primary progressive aphasia and the evolving neurology of the language network.

Mesulam MM, Rogalski EJ, Wieneke C, Hurley RS, Geula C, Bigio EH, Thompson CK, Weintraub S.

Nat Rev Neurol. 2014 Oct;10(10):554-69. doi: 10.1038/nrneurol.2014.159. Epub 2014 Sep 2. Review.

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