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Items: 1 to 50 of 407

1.

Glucocorticoids Reduce Aberrant O-Glycosylation of IgA1 in IgA Nephropathy Patients.

Kosztyu P, Hill M, Jemelkova J, Czernekova L, Kafkova LR, Hruby M, Matousovic K, Vondrak K, Zadrazil J, Sterzl I, Mestecky J, Raska M.

Kidney Blood Press Res. 2018;43(2):350-359. doi: 10.1159/000487903. Epub 2018 Mar 6.

2.

Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy.

Nabi R, Moldoveanu Z, Wei Q, Golub ET, Durkin HG, Greenblatt RM, Herold BC, Nowicki MJ, Kassaye S, Cho MW, Pinter A, Landay AL, Mestecky J, Kozlowski PA.

PLoS One. 2017 Jul 3;12(7):e0180245. doi: 10.1371/journal.pone.0180245. eCollection 2017.

3.

Two Cells, One Antibody: The Discovery of the Cellular Origins and Transport of Secretory IgA.

Kaetzel CS, Mestecky J, Johansen FE.

J Immunol. 2017 Mar 1;198(5):1765-1767. doi: 10.4049/jimmunol.1700025. No abstract available.

4.

Diminished CD103 (αEβ7) Expression on Resident T Cells from the Female Genital Tract of HIV-Positive Women.

Moylan DC, Goepfert PA, Kempf MC, Saag MS, Richter HE, Mestecky J, Sabbaj S.

Pathog Immun. 2016 Fall-Winter;1(2):371-387. doi: 10.20411/pai.v1i2.166. Epub 2017 Jan 16.

5.

Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection.

Hel Z, Xu J, Denning WL, Helton ES, Huijbregts RP, Heath SL, Overton ET, Christmann BS, Elson CO, Goepfert PA, Mestecky J.

PLoS Pathog. 2017 Jan 26;13(1):e1006087. doi: 10.1371/journal.ppat.1006087. eCollection 2017 Jan.

6.

[IgA nephropathy - research-generated questions].

Raška M, Zadražil J, Horynová MS, Kafková LR, Vráblíková A, Matoušovic K, Novak J, Městecký J.

Vnitr Lek. 2016 Winter;62 Suppl 6:67-77. Czech.

PMID:
28124935
7.

IgA nephropathy enigma.

Mestecky J, Novak J, Moldoveanu Z, Raska M.

Clin Immunol. 2016 Nov;172:72-77. doi: 10.1016/j.clim.2016.07.011. Epub 2016 Jul 18. Review.

8.

The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy.

Knoppova B, Reily C, Maillard N, Rizk DV, Moldoveanu Z, Mestecky J, Raska M, Renfrow MB, Julian BA, Novak J.

Front Immunol. 2016 Apr 12;7:117. doi: 10.3389/fimmu.2016.00117. eCollection 2016. Review.

9.

Characterization of serum antibodies from women immunized with Gardasil: A study of HPV-18 infection of primary human keratinocytes.

Wang HK, Wei Q, Moldoveanu Z, Huh WK, Vu HL, Broker TR, Mestecky J, Chow LT.

Vaccine. 2016 Jun 8;34(27):3171-3177. doi: 10.1016/j.vaccine.2016.04.038. Epub 2016 Apr 23.

10.

[IgA Nephropathy. Facts, uncertainties, and potential causal therapy approaches].

Matoušovic K, Městecký J, Vondrák K, Dušek J, Chvátalová E, Háček J, Horynová M, Kašperová A, Rossmann P, Šterzl I, Raška M.

Cas Lek Cesk. 2015;154(4):168-73. Review. Czech.

PMID:
26357858
11.

Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.

Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter M, Yuan S, Yan J, Ginsberg A, Sylvester A, Pahar B, Carnathan D, Kathuria N, Khan AS, Montefiori D, Sardesai NY, Betts MR, Mestecky J, Marx P, Weiner DB.

Mucosal Immunol. 2016 Jan;9(1):13-23. doi: 10.1038/mi.2015.31. Epub 2015 May 6.

12.

Cellular signaling and production of galactose-deficient IgA1 in IgA nephropathy, an autoimmune disease.

Reily C, Ueda H, Huang ZQ, Mestecky J, Julian BA, Willey CD, Novak J.

J Immunol Res. 2014;2014:197548. doi: 10.1155/2014/197548. Epub 2014 Jul 23. Review.

13.

Origin of galactose-deficient immunoglobulin g in gingival crevicular fluid in periodontitis.

Komiyama Y, Kafkova LR, Barasch A, Shah GR, Grbic JT, Novak Z, Komiyama K, Novak J, Mestecky J, Moldoveanu Z.

J Periodontol. 2014 Dec;85(12):1779-85. doi: 10.1902/jop.2014.140212.

PMID:
25152004
14.

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection.

Raska M, Czernekova L, Moldoveanu Z, Zachova K, Elliott MC, Novak Z, Hall S, Hoelscher M, Maboko L, Brown R, Smith PD, Mestecky J, Novak J.

AIDS Res Ther. 2014 Aug 1;11:23. doi: 10.1186/1742-6405-11-23. eCollection 2014.

15.

Humoral immune responses to HIV in the mucosal secretions and sera of HIV-infected women.

Mestecky J, Wei Q, Alexander R, Raska M, Novak J, Moldoveanu Z.

Am J Reprod Immunol. 2014 Jun;71(6):600-7. doi: 10.1111/aji.12203. Epub 2014 Feb 5. Review.

16.

The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.

Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN.

PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013 Nov 21. Erratum in: PLoS Pathog. 2013 Nov;9(11). doi:10.1371/annotation/31430955-703b-484a-96eb-e180f917d683.

17.

Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women.

Wei Q, Moldoveanu Z, Huang WQ, Alexander RC, Goepfert PA, Mestecky J.

Open AIDS J. 2012;6:293-302. doi: 10.2174/1874613601206010293. Epub 2012 Dec 28.

18.

IgA nephropathy: molecular mechanisms of the disease.

Mestecky J, Raska M, Julian BA, Gharavi AG, Renfrow MB, Moldoveanu Z, Novak L, Matousovic K, Novak J.

Annu Rev Pathol. 2013 Jan 24;8:217-40. doi: 10.1146/annurev-pathol-011110-130216. Epub 2012 Oct 18. Review.

PMID:
23092188
19.

Glycosylation of IgA1 and pathogenesis of IgA nephropathy.

Novak J, Julian BA, Mestecky J, Renfrow MB.

Semin Immunopathol. 2012 May;34(3):365-82. doi: 10.1007/s00281-012-0306-z. Epub 2012 Mar 21. Review.

PMID:
22434325
20.

In vitro-generated immune complexes containing galactose-deficient IgA1 stimulate proliferation of mesangial cells.

Yanagihara T, Brown R, Hall S, Moldoveanu Z, Goepfert A, Tomana M, Julian BA, Mestecky J, Novak J.

Results Immunol. 2012 Jan 1;2:166-172.

21.

Menstrual blood as a potential source of endometrial derived CD3+ T cells.

Sabbaj S, Hel Z, Richter HE, Mestecky J, Goepfert PA.

PLoS One. 2011;6(12):e28894. doi: 10.1371/journal.pone.0028894. Epub 2011 Dec 9.

22.

[Strategic dominance of the mucosal immune system in the defence and tolerance].

Mestecký J, Raska M.

Cas Lek Cesk. 2011;150(9):480-8. Review. Czech.

PMID:
22132615
23.

Naturally occurring structural isomers in serum IgA1 o-glycosylation.

Takahashi K, Smith AD, Poulsen K, Kilian M, Julian BA, Mestecky J, Novak J, Renfrow MB.

J Proteome Res. 2012 Feb 3;11(2):692-702. doi: 10.1021/pr200608q. Epub 2011 Dec 29.

24.

The pathophysiology of IgA nephropathy.

Suzuki H, Kiryluk K, Novak J, Moldoveanu Z, Herr AB, Renfrow MB, Wyatt RJ, Scolari F, Mestecky J, Gharavi AG, Julian BA.

J Am Soc Nephrol. 2011 Oct;22(10):1795-803. doi: 10.1681/ASN.2011050464. Epub 2011 Sep 23. Review.

25.

Aberrant glycosylation of IgA1 and anti-glycan antibodies in IgA nephropathy: role of mucosal immune system.

Novak J, Moldoveanu Z, Julian BA, Raska M, Wyatt RJ, Suzuki Y, Tomino Y, Gharavi AG, Mestecky J, Suzuki H.

Adv Otorhinolaryngol. 2011;72:60-3. doi: 10.1159/000324607. Epub 2011 Aug 18. Review.

PMID:
21865691
26.

IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.

Novak J, Raskova Kafkova L, Suzuki H, Tomana M, Matousovic K, Brown R, Hall S, Sanders JT, Eison TM, Moldoveanu Z, Novak L, Novak Z, Mayne R, Julian BA, Mestecky J, Wyatt RJ.

Nephrol Dial Transplant. 2011 Nov;26(11):3451-7. doi: 10.1093/ndt/gfr448. Epub 2011 Aug 9.

27.

Humoral immune response to keyhole limpet haemocyanin, the protein carrier in cancer vaccines.

Kantele A, Häkkinen MP, Zivny J, Elson CO, Mestecky J, Kantele JM.

Clin Dev Immunol. 2011;2011:614383. doi: 10.1155/2011/614383. Epub 2011 Jun 12.

28.

Systemic and mucosal differences in HIV burden, immune, and therapeutic responses.

Wahl SM, Redford M, Christensen S, Mack W, Cohn J, Janoff EN, Mestecky J, Jenson HB, Navazesh M, Cohen M, Reichelderfer P, Kovacs A; DATRI 009 Study Group.

J Acquir Immune Defic Syndr. 2011 Apr 15;56(5):401-11. doi: 10.1097/QAI.0b013e31820cdfdb.

29.

Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women.

Mestecky J, Wright PF, Lopalco L, Staats HF, Kozlowski PA, Moldoveanu Z, Alexander RC, Kulhavy R, Pastori C, Maboko L, Riedner G, Zhu Y, Wrinn T, Hoelscher M.

AIDS Res Hum Retroviruses. 2011 May;27(5):469-86. doi: 10.1089/aid.2010.0169. Epub 2010 Nov 22.

30.

Methods for evaluation of humoral immune responses in human genital tract secretions.

Mestecky J, Alexander RC, Wei Q, Moldoveanu Z.

Am J Reprod Immunol. 2011 Mar;65(3):361-7. doi: 10.1111/j.1600-0897.2010.00923.x. Epub 2010 Nov 19. Review.

31.

Enhancing oral vaccine potency by targeting intestinal M cells.

Azizi A, Kumar A, Diaz-Mitoma F, Mestecky J.

PLoS Pathog. 2010 Nov 11;6(11):e1001147. doi: 10.1371/journal.ppat.1001147. Review.

32.

Clustered O-glycans of IgA1: defining macro- and microheterogeneity by use of electron capture/transfer dissociation.

Takahashi K, Wall SB, Suzuki H, Smith AD 4th, Hall S, Poulsen K, Kilian M, Mobley JA, Julian BA, Mestecky J, Novak J, Renfrow MB.

Mol Cell Proteomics. 2010 Nov;9(11):2545-57. doi: 10.1074/mcp.M110.001834. Epub 2010 Sep 7.

33.

Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study.

Gomes MM, Suzuki H, Brooks MT, Tomana M, Moldoveanu Z, Mestecky J, Julian BA, Novak J, Herr AB.

Biochemistry. 2010 Jul 13;49(27):5671-82. doi: 10.1021/bi9019498.

34.

Tolerance and protection against infection in the genital tract.

Russell MW, Mestecky J.

Immunol Invest. 2010;39(4-5):500-25. doi: 10.3109/08820131003674834. Review.

PMID:
20450289
35.

Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.

Raska M, Takahashi K, Czernekova L, Zachova K, Hall S, Moldoveanu Z, Elliott MC, Wilson L, Brown R, Jancova D, Barnes S, Vrbkova J, Tomana M, Smith PD, Mestecky J, Renfrow MB, Novak J.

J Biol Chem. 2010 Jul 2;285(27):20860-9. doi: 10.1074/jbc.M109.085472. Epub 2010 May 3.

36.

Mucosal HIV vaccines: a holy grail or a dud?

Azizi A, Ghunaim H, Diaz-Mitoma F, Mestecky J.

Vaccine. 2010 May 28;28(24):4015-26. doi: 10.1016/j.vaccine.2010.04.018. Epub 2010 Apr 20. Review.

PMID:
20412879
37.

Antibody-mediated protection and the mucosal immune system of the genital tract: relevance to vaccine design.

Mestecky J, Raska M, Novak J, Alexander RC, Moldoveanu Z.

J Reprod Immunol. 2010 May;85(1):81-5. doi: 10.1016/j.jri.2010.02.003. Epub 2010 Mar 16. Review.

38.

Expression of homing receptors on IgA1 and IgA2 plasmablasts in blood reflects differential distribution of IgA1 and IgA2 in various body fluids.

Pakkanen SH, Kantele JM, Moldoveanu Z, Hedges S, Häkkinen M, Mestecky J, Kantele A.

Clin Vaccine Immunol. 2010 Mar;17(3):393-401. doi: 10.1128/CVI.00475-09. Epub 2010 Jan 20.

39.

Tissue distribution and biological activities of immune complexes are determined by their size and composition.

Matousovic K, Novak J, Julian BA, Mestecky J.

Nephrol Dial Transplant. 2010 Mar;25(3):1007. doi: 10.1093/ndt/gfp585. Epub 2009 Nov 13. No abstract available.

PMID:
19914998
40.

Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection.

Hel Z, Stringer E, Mestecky J.

Endocr Rev. 2010 Feb;31(1):79-97. doi: 10.1210/er.2009-0018. Epub 2009 Nov 10. Review.

41.

Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection.

Mestecky J, Moldoveanu Z, Smith PD, Hel Z, Alexander RC.

J Reprod Immunol. 2009 Dec;83(1-2):196-200. doi: 10.1016/j.jri.2009.07.005. Epub 2009 Oct 23. Review.

42.

Specific antibody activity, glycan heterogeneity and polyreactivity contribute to the protective activity of S-IgA at mucosal surfaces.

Mestecky J, Russell MW.

Immunol Lett. 2009 Jun 4;124(2):57-62. doi: 10.1016/j.imlet.2009.03.013. Epub 2009 Apr 5. Review.

43.

Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.

Suzuki H, Fan R, Zhang Z, Brown R, Hall S, Julian BA, Chatham WW, Suzuki Y, Wyatt RJ, Moldoveanu Z, Lee JY, Robinson J, Tomana M, Tomino Y, Mestecky J, Novak J.

J Clin Invest. 2009 Jun;119(6):1668-77. doi: 10.1172/JCI38468. Epub 2009 May 26.

44.

Oral immunization: an update.

Mestecky J, Nguyen H, Czerkinsky C, Kiyono H.

Curr Opin Gastroenterol. 2008 Nov;24(6):713-9. doi: 10.1097/MOG.0b013e32830d58be. Review.

PMID:
19122521
45.

Mucosal antibody responses to HIV.

Moldoveanu Z, Mestecky J.

Methods Mol Biol. 2009;485:333-45. doi: 10.1007/978-1-59745-170-3_22.

PMID:
19020835
46.

[Treatment of IgA nephropathy].

Matousovic K, Mestecky J, Tomana M, Novak J.

Vnitr Lek. 2008 Mar;54(3):239-44. Review. Czech.

PMID:
18522291
47.

Delivery of DNA HIV-1 vaccine to the liver induces high and long-lasting humoral immune responses.

Raska M, Moldoveanu Z, Novak J, Hel Z, Novak L, Bozja J, Compans RW, Yang C, Mestecky J.

Vaccine. 2008 Mar 17;26(12):1541-51. doi: 10.1016/j.vaccine.2008.01.035. Epub 2008 Feb 7.

48.

Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy.

Gharavi AG, Moldoveanu Z, Wyatt RJ, Barker CV, Woodford SY, Lifton RP, Mestecky J, Novak J, Julian BA.

J Am Soc Nephrol. 2008 May;19(5):1008-14. doi: 10.1681/ASN.2007091052. Epub 2008 Feb 13.

49.

IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy.

Novak J, Julian BA, Tomana M, Mestecky J.

Semin Nephrol. 2008 Jan;28(1):78-87. doi: 10.1016/j.semnephrol.2007.10.009. Review.

50.

Peyer's patches as the inductive site for IgA responses.

Mestecky J, Elson CO.

J Immunol. 2008 Feb 1;180(3):1293-4. No abstract available.

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