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Items: 46


Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over.

Du Puy RS, Postmus I, Stott DJ, Blum MR, Poortvliet RKE, Den Elzen WPJ, Peeters RP, van Munster BC, Wolffenbuttel BHR, Westendorp RGJ, Kearney PM, Ford I, Kean S, Messow CM, Watt T, Jukema JW, Dekkers OM, Smit JWA, Rodondi N, Gussekloo J, Mooijaart SP.

BMC Endocr Disord. 2018 Sep 19;18(1):67. doi: 10.1186/s12902-018-0285-8.


Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM).

Norman JE, Marlow N, Messow CM, Shennan A, Bennett PR, Thornton S, Robson SC, McConnachie A, Petrou S, Sebire NJ, Lavender T, Whyte S, Norrie J.

Health Technol Assess. 2018 Jun;22(35):1-304. doi: 10.3310/hta22350.


Randomised, double-blind, placebo-controlled trials of non-individualised homeopathic treatment: systematic review and meta-analysis.

Mathie RT, Ramparsad N, Legg LA, Clausen J, Moss S, Davidson JR, Messow CM, McConnachie A.

Syst Rev. 2017 Mar 24;6(1):63. doi: 10.1186/s13643-017-0445-3. Review.


Meta-analysis of statins in chronic kidney disease: who benefits?

Messow CM, Isles C.

QJM. 2017 Aug 1;110(8):493-500. doi: 10.1093/qjmed/hcx040.


Age-adjusted D-dimer excludes pulmonary embolism and reduces unnecessary radiation exposure in older adults: retrospective study.

Nobes J, Messow CM, Khan M, Hrobar P, Isles C.

Postgrad Med J. 2017 Jul;93(1101):420-424. doi: 10.1136/postgradmedj-2016-134552. Epub 2016 Dec 9.


Endovascular therapy for acute ischaemic stroke: the Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial.

Muir KW, Ford GA, Messow CM, Ford I, Murray A, Clifton A, Brown MM, Madigan J, Lenthall R, Robertson F, Dixit A, Cloud GC, Wardlaw J, Freeman J, White P; PISTE Investigators.

J Neurol Neurosurg Psychiatry. 2017 Jan;88(1):38-44. doi: 10.1136/jnnp-2016-314117. Epub 2016 Oct 18.


Association between GDF-15 levels and changes in vascular and physical function in older patients with hypertension.

Barma M, Khan F, Price RJG, Donnan PT, Messow CM, Ford I, McConnachie A, Struthers AD, McMurdo MET, Witham MD.

Aging Clin Exp Res. 2017 Oct;29(5):1055-1059. doi: 10.1007/s40520-016-0636-0. Epub 2016 Oct 12.


Excessive Age-Related Decline in Functional Ovarian Reserve in Infertile Women: Prospective Cohort of 15,500 Women.

Iliodromiti S, Iglesias Sanchez C, Messow CM, Cruz M, Garcia Velasco J, Nelson SM.

J Clin Endocrinol Metab. 2016 Sep;101(9):3548-54. doi: 10.1210/jc.2015-4279. Epub 2016 Jul 6.


Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled, non-inferiority, trial.

Porter D, van Melckebeke J, Dale J, Messow CM, McConnachie A, Walker A, Munro R, McLaren J, McRorie E, Packham J, Buckley CD, Harvie J, Taylor P, Choy E, Pitzalis C, McInnes IB.

Lancet. 2016 Jul 16;388(10041):239-47. doi: 10.1016/S0140-6736(16)00380-9. Epub 2016 May 17.


Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial.

Norman JE, Marlow N, Messow CM, Shennan A, Bennett PR, Thornton S, Robson SC, McConnachie A, Petrou S, Sebire NJ, Lavender T, Whyte S, Norrie J; OPPTIMUM study group.

Lancet. 2016 May 21;387(10033):2106-2116. doi: 10.1016/S0140-6736(16)00350-0. Epub 2016 Feb 24.


Counselling versus low-intensity cognitive behavioural therapy for persistent sub-threshold and mild depression (CLICD): a pilot/feasibility randomised controlled trial.

Freire E, Williams C, Messow CM, Cooper M, Elliott R, McConnachie A, Walker A, Heard D, Morrison J.

BMC Psychiatry. 2015 Aug 15;15:197. doi: 10.1186/s12888-015-0582-y.


Radiotherapy-induced xerostomia, pre-clinical promise of LMS-611.

Paterson C, Caldwell B, Porteous S, McLean A, Messow CM, Thomson M.

Support Care Cancer. 2016 Feb;24(2):629-636. doi: 10.1007/s00520-015-2823-5. Epub 2015 Jul 5.


Poor symptom control is associated with reduced CT scan segmental airway lumen area in smokers with asthma.

Thomson NC, Chaudhuri R, Spears M, Messow CM, MacNee W, Connell M, Murchison JT, Sproule M, McSharry C.

Chest. 2015 Mar;147(3):735-744. doi: 10.1378/chest.14-1119. Erratum in: Chest. 2015 Aug;148(2):572.


Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma.

Chaudhuri R, McSharry C, Brady J, Grierson C, Messow CM, Spears M, Miele G, Nocka K, MacNee W, Connell M, Murchison JT, Sproule M, Hilmi OJ, Miller DK, Thomson NC.

Eur Respir J. 2014 Oct;44(4):895-904. doi: 10.1183/09031936.00047014. Epub 2014 Jul 3.


Arachidonic acid metabolites and enzyme transcripts in asthma are altered by cigarette smoking.

Thomson NC, Chaudhuri R, Spears M, Messow CM, Jelinsky S, Miele G, Nocka K, Takahashi E, Hilmi OJ, Shepherd MC, Miller DK, McSharry C.

Allergy. 2014 Apr;69(4):527-36. doi: 10.1111/all.12376. Epub 2014 Feb 26.


Sputum matrix metalloproteinase-9 is associated with the degree of emphysema on computed tomography in COPD.

Chaudhuri R, McSharry C, Spears M, Brady J, Grierson C, Messow CM, Miele G, Nocka K, MacNee W, Connell M, Murchison JT, Sproule M, Hilmi O, Miller DK, Thomson NC.

Transl Respir Med. 2013 Dec;1(1):11. doi: 10.1186/2213-0802-1-11. Epub 2013 Jun 6.


Reference range for the antimüllerian hormone Generation II assay: a population study of 10,984 women, with comparison to the established Diagnostics Systems Laboratory nomogram.

Nelson SM, Iliodromiti S, Fleming R, Anderson R, McConnachie A, Messow CM.

Fertil Steril. 2014 Feb;101(2):523-9. doi: 10.1016/j.fertnstert.2013.10.021. Epub 2013 Nov 9.


Cholecalciferol treatment to reduce blood pressure in older patients with isolated systolic hypertension: the VitDISH randomized controlled trial.

Witham MD, Price RJ, Struthers AD, Donnan PT, Messow CM, Ford I, McMurdo ME.

JAMA Intern Med. 2013 Oct 14;173(18):1672-9.


Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma.

Thomson NC, Chaudhuri R, Messow CM, Spears M, MacNee W, Connell M, Murchison JT, Sproule M, McSharry C.

Respir Med. 2013 Oct;107(10):1501-8. doi: 10.1016/j.rmed.2013.07.017. Epub 2013 Aug 6.


The relationship between anti-Müllerian hormone in women receiving fertility assessments and age at menopause in subfertile women: evidence from large population studies.

Dólleman M, Faddy MJ, van Disseldorp J, van der Schouw YT, Messow CM, Leader B, Peeters PH, McConnachie A, Nelson SM, Broekmans FJ.

J Clin Endocrinol Metab. 2013 May;98(5):1946-53. doi: 10.1210/jc.2012-4228. Epub 2013 Mar 18.


Searching for gene expression differences in primary fibroblasts between patients with one and two neoplasms in childhood.

Victor A, Weis E, Messow CM, Marron M, Haaf T, Spix C, Galetzka D.

Pediatr Hematol Oncol. 2013 Feb;30(1):33-45. doi: 10.3109/08880018.2012.735747. Epub 2012 Nov 9.


Feasibility of screening for and treating vitamin D deficiency in forensic psychiatric inpatients.

Murie J, Messow CM, Fitzpatrick B.

J Forensic Leg Med. 2012 Nov;19(8):457-64. doi: 10.1016/j.jflm.2012.04.003. Epub 2012 May 4.


Interaction of personality traits with social deprivation in determining mental wellbeing and health behaviours.

Packard CJ, Cavanagh J, McLean JS, McConnachie A, Messow CM, Batty GD, Burns H, Deans KA, Sattar N, Shiels PG, Velupillai YN, Tannahill C, Millar K.

J Public Health (Oxf). 2012 Dec;34(4):615-24. doi: 10.1093/pubmed/fds030. Epub 2012 May 2.


Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity.

Chaudhuri R, McSharry C, Brady J, Donnelly I, Grierson C, McGuinness S, Jolly L, Weir CJ, Messow CM, Spears M, Miele G, Nocka K, Crowther D, Thompson J, Brannigan M, Lafferty J, Sproule M, Macnee W, Connell M, Murchison JT, Shepherd MC, Feuerstein G, Miller DK, Thomson NC.

J Allergy Clin Immunol. 2012 Mar;129(3):655-663.e8. doi: 10.1016/j.jaci.2011.12.996. Epub 2012 Feb 2. Erratum in: J Allergy Clin Immunol. 2013 Jun;131(6):1716.


A new approach to scoring systems to improve identification of acute medical admissions that will require critical care.

Carmichael HA, Robertson E, Austin J, McCruden D, Messow CM, Belcher PR.

Scott Med J. 2011 Nov;56(4):195-202. doi: 10.1258/smj.2011.011157.


Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta-analysis.

Lim WY, Messow CM, Berry C.

Br J Pharmacol. 2012 Apr;165(7):2034-43. doi: 10.1111/j.1476-5381.2011.01691.x. Review.


The Heart failure and Optimal Outcomes from Pharmacy Study (HOOPS): rationale, design, and baseline characteristics.

Lowrie R, Mair FS, Greenlaw N, Forsyth P, McConnachie A, Richardson J, Khan N, Morrison D, Messow CM, Rae B, McMurray JJ.

Eur J Heart Fail. 2011 Aug;13(8):917-24. doi: 10.1093/eurjhf/hfr083.


First-trimester circulating 25-hydroxyvitamin D levels and development of gestational diabetes mellitus.

Makgoba M, Nelson SM, Savvidou M, Messow CM, Nicolaides K, Sattar N.

Diabetes Care. 2011 May;34(5):1091-3. doi: 10.2337/dc10-2264. Epub 2011 Mar 31.


First-trimester prediction of gestational diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures.

Savvidou M, Nelson SM, Makgoba M, Messow CM, Sattar N, Nicolaides K.

Diabetes. 2010 Dec;59(12):3017-22. doi: 10.2337/db10-0688. Epub 2010 Sep 28.


Multiple marker approach to risk stratification in patients with stable coronary artery disease.

Schnabel RB, Schulz A, Messow CM, Lubos E, Wild PS, Zeller T, Sinning CR, Rupprecht HJ, Bickel C, Peetz D, Cambien F, Kempf T, Wollert KC, Benjamin EJ, Lackner KJ, Münzel TF, Tiret L, Vasan RS, Blankenberg S.

Eur Heart J. 2010 Dec;31(24):3024-31. doi: 10.1093/eurheartj/ehq322. Epub 2010 Sep 18.


Limited clinical utility of CT coronary angiography in a district hospital setting.

Jenkins SM, Johnston N, Hawkins NM, Messow CM, Shand J, Hogg KJ, Eteiba H, McKillop G, Goodfield NE, McConnachie A, Dunn FG.

QJM. 2011 Jan;104(1):49-57. doi: 10.1093/qjmed/hcq163. Epub 2010 Sep 16.


Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis.

Wörns MA, Weinmann A, Pfingst K, Schulte-Sasse C, Messow CM, Schulze-Bergkamen H, Teufel A, Schuchmann M, Kanzler S, Düber C, Otto G, Galle PR.

J Clin Gastroenterol. 2009 May-Jun;43(5):489-95. doi: 10.1097/MCG.0b013e31818ddfc6.


Cystatin C and cardiovascular mortality in patients with coronary artery disease and normal or mildly reduced kidney function: results from the AtheroGene study.

Keller T, Messow CM, Lubos E, Nicaud V, Wild PS, Rupprecht HJ, Bickel C, Tzikas S, Peetz D, Lackner KJ, Tiret L, Münzel TF, Blankenberg S, Schnabel RB.

Eur Heart J. 2009 Feb;30(3):314-20. doi: 10.1093/eurheartj/ehn598. Epub 2009 Jan 19.


Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.

Schnabel R, Lubos E, Messow CM, Sinning CR, Zeller T, Wild PS, Peetz D, Handy DE, Munzel T, Loscalzo J, Lackner KJ, Blankenberg S.

Am Heart J. 2008 Dec;156(6):1201.e1-11. doi: 10.1016/j.ahj.2008.09.004.


B-type natriuretic peptide as a marker for sepsis-induced myocardial depression in intensive care patients.

Post F, Weilemann LS, Messow CM, Sinning C, Münzel T.

Crit Care Med. 2008 Nov;36(11):3030-7. doi: 10.1097/CCM.0b013e31818b9153.


Anticoagulant and/or antiplatelet treatment in patients with atrial fibrillation after percutaneous coronary intervention. A single-center experience.

Maegdefessel L, Schlitt A, Faerber J, Bond SP, Messow CM, Buerke M, Raaz U, Werdan K, Muenzel T, Weiss C.

Med Klin (Munich). 2008 Sep 15;103(9):628-32. doi: 10.1007/s00063-008-1101-4. Epub 2008 Sep 24.


Different calculations of ankle-brachial index and their impact on cardiovascular risk prediction.

Espinola-Klein C, Rupprecht HJ, Bickel C, Lackner K, Savvidis S, Messow CM, Munzel T, Blankenberg S; AtheroGene Investigators.

Circulation. 2008 Aug 26;118(9):961-7. doi: 10.1161/CIRCULATIONAHA.107.763227. Epub 2008 Aug 12.


[New perspectives in laparoscopic simulation: from students' skills lab to stress evaluation].

Gockel I, Hakman P, Beardi J, Schütz M, Heinrichs W, Messow CM, Junginger T.

Zentralbl Chir. 2008 Jun;133(3):244-9. doi: 10.1055/s-2008-1004744. German.


Sparse kernel methods for high-dimensional survival data.

Evers L, Messow CM.

Bioinformatics. 2008 Jul 15;24(14):1632-8. doi: 10.1093/bioinformatics/btn253. Epub 2008 May 30.


Association of adiponectin with adverse outcome in coronary artery disease patients: results from the AtheroGene study.

Schnabel R, Messow CM, Lubos E, Espinola-Klein C, Rupprecht HJ, Bickel C, Sinning C, Tzikas S, Keller T, Genth-Zotz S, Lackner KJ, Münzel TF, Blankenberg S.

Eur Heart J. 2008 Mar;29(5):649-57. doi: 10.1093/eurheartj/ehn009. Epub 2008 Feb 9.


Femoropopliteal prosthetic bypass with glutaraldehyde stabilized human umbilical vein (HUV).

Neufang A, Espinola-Klein C, Dorweiler B, Messow CM, Schmiedt W, Vahl CF.

J Vasc Surg. 2007 Aug;46(2):280-8. Epub 2007 Jun 27.


Impact of C-reactive protein and fibrinogen on cardiovascular prognosis in patients with stable angina pectoris: the AtheroGene study.

Sinning JM, Bickel C, Messow CM, Schnabel R, Lubos E, Rupprecht HJ, Espinola-Klein C, Lackner KJ, Tiret L, Münzel T, Blankenberg S; AtheroGene Investigators.

Eur Heart J. 2006 Dec;27(24):2962-8. Epub 2006 Nov 28.


Resistin, acute coronary syndrome and prognosis results from the AtheroGene study.

Lubos E, Messow CM, Schnabel R, Rupprecht HJ, Espinola-Klein C, Bickel C, Peetz D, Post F, Lackner KJ, Tiret L, Münzel T, Blankenberg S.

Atherosclerosis. 2007 Jul;193(1):121-8. Epub 2006 Jun 30.


Prognostic value of tissue inhibitor of metalloproteinase-1 for cardiovascular death among patients with cardiovascular disease: results from the AtheroGene study.

Lubos E, Schnabel R, Rupprecht HJ, Bickel C, Messow CM, Prigge S, Cambien F, Tiret L, Münzel T, Blankenberg S.

Eur Heart J. 2006 Jan;27(2):150-6. Epub 2005 Oct 17.


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