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TTA-P2 is a potent and selective blocker of T-type calcium channels in rat sensory neurons and a novel antinociceptive agent.

Choe W, Messinger RB, Leach E, Eckle VS, Obradovic A, Salajegheh R, Jevtovic-Todorovic V, Todorovic SM.

Mol Pharmacol. 2011 Nov;80(5):900-10. doi: 10.1124/mol.111.073205. Epub 2011 Aug 5.


In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy.

Messinger RB, Naik AK, Jagodic MM, Nelson MT, Lee WY, Choe WJ, Orestes P, Latham JR, Todorovic SM, Jevtovic-Todorovic V.

Pain. 2009 Sep;145(1-2):184-95. doi: 10.1016/j.pain.2009.06.012. Epub 2009 Jul 3.

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