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Items: 1 to 50 of 104

1.

Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.

Lionello VM, Nicot AS, Sartori M, Kretz C, Kessler P, Buono S, Djerroud S, Messaddeq N, Koebel P, Prokic I, Hérault Y, Romero NB, Laporte J, Cowling BS.

Sci Transl Med. 2019 Mar 20;11(484). pii: eaav1866. doi: 10.1126/scitranslmed.aav1866.

PMID:
30894500
2.

Toward the Formulation of Stable Micro and Nano Double Emulsions through a Silica Coating on Internal Water Droplets.

Akram S, Wang X, Vandamme TF, Collot M, Rehman AU, Messaddeq N, Mély Y, Anton N.

Langmuir. 2019 Feb 12;35(6):2313-2325. doi: 10.1021/acs.langmuir.8b03919. Epub 2019 Jan 24.

PMID:
30630316
3.

STIM1 over-activation generates a multi-systemic phenotype affecting skeletal muscle, spleen, eye, skin, bones, and the immune system in mice.

Silva-Rojas R, Treves S, Jacobs H, Kessler P, Messaddeq N, Laporte J, Böhm J.

Hum Mol Genet. 2018 Dec 21. doi: 10.1093/hmg/ddy446. [Epub ahead of print]

PMID:
30576443
4.

Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging.

Wallyn J, Anton N, Mertz D, Begin-Colin S, Perton F, Serra CA, Franconi F, Lemaire L, Chiper M, Libouban H, Messaddeq N, Anton H, Vandamme TF.

ACS Appl Mater Interfaces. 2019 Jan 9;11(1):403-416. doi: 10.1021/acsami.8b19517. Epub 2018 Dec 26.

PMID:
30541280
5.

Abnormal lipid storage related to adipocyte shrinkage in acquired partial lipodystrophy (Barraquer-Simons syndrome).

Velter C, Messaddeq N, Levy E, Morruzzi C, Cribier B, Dali-Youcef N, Lipsker D.

J Eur Acad Dermatol Venereol. 2018 Nov 25. doi: 10.1111/jdv.15366. [Epub ahead of print]

PMID:
30472754
6.

Loss of zebrafish Ataxin-7, a SAGA subunit responsible for SCA7 retinopathy, causes ocular coloboma and malformation of photoreceptors.

Carrillo-Rosas S, Weber C, Fievet L, Messaddeq N, Karam A, Trottier Y.

Hum Mol Genet. 2018 Nov 16. doi: 10.1093/hmg/ddy401. [Epub ahead of print]

PMID:
30445451
7.

Pickering nano-emulsion as a nanocarrier for pH-triggered drug release.

Sy PM, Anton N, Idoux-Gillet Y, Dieng SM, Messaddeq N, Ennahar S, Diarra M, Vandamme TF.

Int J Pharm. 2018 Oct 5;549(1-2):299-305. doi: 10.1016/j.ijpharm.2018.07.066. Epub 2018 Jul 31.

PMID:
30075249
8.

Modulation of large dense core vesicle insulin content mediates rhythmic hormone release from pancreatic beta cells over the 24h cycle.

Quinault A, Leloup C, Denwood G, Spiegelhalter C, Rodriguez M, Lefebvre P, Messaddeq N, Zhang Q, Dacquet C, Pénicaud L, Collins SC.

PLoS One. 2018 Mar 15;13(3):e0193882. doi: 10.1371/journal.pone.0193882. eCollection 2018.

9.

Single Intramuscular Injection of AAV-shRNA Reduces DNM2 and Prevents Myotubular Myopathy in Mice.

Tasfaout H, Lionello VM, Kretz C, Koebel P, Messaddeq N, Bitz D, Laporte J, Cowling BS.

Mol Ther. 2018 Apr 4;26(4):1082-1092. doi: 10.1016/j.ymthe.2018.02.008. Epub 2018 Feb 14.

10.

Phagocytosis by Sertoli Cells: Analysis of Main Phagocytosis Steps by Confocal and Electron Microscopy.

Yefimova MG, Messaddeq N, Meunier AC, Cantereau A, Jegou B, Bourmeyster N.

Methods Mol Biol. 2018;1748:85-101. doi: 10.1007/978-1-4939-7698-0_8.

PMID:
29453567
11.

The MTM1-UBQLN2-HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle.

Gavriilidis C, Laredj L, Solinhac R, Messaddeq N, Viaud J, Laporte J, Sumara I, Hnia K.

Nat Cell Biol. 2018 Feb;20(2):198-210. doi: 10.1038/s41556-017-0024-9. Epub 2018 Jan 22.

PMID:
29358706
12.

Microfluidic-Assisted Production of Size-Controlled Superparamagnetic Iron Oxide Nanoparticles-Loaded Poly(methyl methacrylate) Nanohybrids.

Ding S, Attia MF, Wallyn J, Taddei C, Serra CA, Anton N, Kassem M, Schmutz M, Er-Rafik M, Messaddeq N, Collard A, Yu W, Giordano M, Vandamme TF.

Langmuir. 2018 Feb 6;34(5):1981-1991. doi: 10.1021/acs.langmuir.7b01928. Epub 2018 Jan 26.

PMID:
29334739
13.

The histone code reader Spin1 controls skeletal muscle development.

Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Günther T, Schüle R.

Cell Death Dis. 2017 Nov 23;8(11):e3173. doi: 10.1038/cddis.2017.468.

14.

A new formulation of poly(MAOTIB) nanoparticles as an efficient contrast agent for in vivo X-ray imaging.

Wallyn J, Anton N, Serra CA, Bouquey M, Collot M, Anton H, Weickert JL, Messaddeq N, Vandamme TF.

Acta Biomater. 2018 Jan 15;66:200-212. doi: 10.1016/j.actbio.2017.11.011. Epub 2017 Nov 9.

PMID:
29129788
15.

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.

Li S, Teegarden A, Bauer EM, Choi J, Messaddeq N, Hendrix DA, Ganguli-Indra G, Leid M, Indra AK.

Sci Rep. 2017 Oct 18;7(1):13427. doi: 10.1038/s41598-017-13347-7.

16.

Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice.

Tasfaout H, Buono S, Guo S, Kretz C, Messaddeq N, Booten S, Greenlee S, Monia BP, Cowling BS, Laporte J.

Nat Commun. 2017 Jun 7;8:15661. doi: 10.1038/ncomms15661.

17.

ISCA1 is essential for mitochondrial Fe4S4 biogenesis in vivo.

Beilschmidt LK, Ollagnier de Choudens S, Fournier M, Sanakis I, Hograindleur MA, Clémancey M, Blondin G, Schmucker S, Eisenmann A, Weiss A, Koebel P, Messaddeq N, Puccio H, Martelli A.

Nat Commun. 2017 May 11;8:15124. doi: 10.1038/ncomms15124.

18.

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.

Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schüle R.

Cell Rep. 2016 Oct 18;17(4):1008-1021. doi: 10.1016/j.celrep.2016.09.053.

19.

Well-organized spheroids as a new platform to examine cell interaction and behaviour during organ development.

Bécavin T, Kuchler-Bopp S, Kökten T, Huck O, Messaddeq N, Lesot H, Deveaux E, Benkirane-Jessel N, Laetitia K.

Cell Tissue Res. 2016 Dec;366(3):601-615. Epub 2016 Sep 6.

PMID:
27599480
20.

Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR.

Yefimova MG, Béré E, Cantereau-Becq A, Harnois T, Meunier AC, Messaddeq N, Becq F, Trottier Y, Bourmeyster N.

Hum Mol Genet. 2016 Oct 1;25(19):4170-4185. doi: 10.1093/hmg/ddw251. Epub 2016 Aug 4.

PMID:
27493027
21.

Corrigendum: Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.

Dali-Youcef N, Hnia K, Blaise S, Messaddeq N, Blanc S, Postic C, Valet P, Tomasetto C, Rio MC.

Sci Rep. 2016 May 31;6:26916. doi: 10.1038/srep26916. No abstract available.

22.

One-step synthesis of iron oxide polypyrrole nanoparticles encapsulating ketoprofen as model of hydrophobic drug.

Attia MF, Anton N, Khan IU, Serra CA, Messaddeq N, Jakhmola A, Vecchione R, Vandamme T.

Int J Pharm. 2016 Jul 11;508(1-2):61-70. doi: 10.1016/j.ijpharm.2016.04.073. Epub 2016 May 7.

PMID:
27163525
23.

Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development.

Arora H, Boulberdaa M, Qureshi R, Bitirim V, Gasser A, Messaddeq N, Dolle P, Nebigil CG.

Sci Rep. 2016 May 6;6:25541. doi: 10.1038/srep25541.

24.

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.

Villaseñor R, Ozmen L, Messaddeq N, Grüninger F, Loetscher H, Keller A, Betsholtz C, Freskgård PO, Collin L.

Sci Rep. 2016 May 6;6:25658. doi: 10.1038/srep25658.

25.

Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.

Dali-Youcef N, Hnia K, Blaise S, Messaddeq N, Blanc S, Postic C, Valet P, Tomasetto C, Rio MC.

Sci Rep. 2016 Apr 29;6:25140. doi: 10.1038/srep25140. Erratum in: Sci Rep. 2016 May 31;6:26916.

26.

The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles.

Gali Ramamoorthy T, Laverny G, Schlagowski AI, Zoll J, Messaddeq N, Bornert JM, Panza S, Ferry A, Geny B, Metzger D.

Nat Commun. 2015 Dec 17;6:10210. doi: 10.1038/ncomms10210.

27.

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

Dubos A, Castells-Nobau A, Meziane H, Oortveld MA, Houbaert X, Iacono G, Martin C, Mittelhaeuser C, Lalanne V, Kramer JM, Bhukel A, Quentin C, Slabbert J, Verstreken P, Sigrist SJ, Messaddeq N, Birling MC, Selloum M, Stunnenberg HG, Humeau Y, Schenck A, Herault Y.

Hum Mol Genet. 2015 Dec 1;24(23):6736-55. doi: 10.1093/hmg/ddv380. Epub 2015 Sep 16.

28.

Microfluidic conceived Trojan microcarriers for oral delivery of nanoparticles.

Khan IU, Serra CA, Anton N, Er-Rafik M, Blanck C, Schmutz M, Kraus I, Messaddeq N, Sutter C, Anton H, Klymchenko AS, Vandamme TF.

Int J Pharm. 2015 Sep 30;493(1-2):7-15. doi: 10.1016/j.ijpharm.2015.06.028. Epub 2015 Jun 23.

PMID:
26116014
29.

Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies.

Ramspacher C, Steed E, Boselli F, Ferreira R, Faggianelli N, Roth S, Spiegelhalter C, Messaddeq N, Trinh L, Liebling M, Chacko N, Tessadori F, Bakkers J, Laporte J, Hnia K, Vermot J.

Cell Rep. 2015 Jun 16;11(10):1564-76. doi: 10.1016/j.celrep.2015.05.010. Epub 2015 Jun 4.

30.

A novel function of Huntingtin in the cilium and retinal ciliopathy in Huntington's disease mice.

Karam A, Tebbe L, Weber C, Messaddeq N, Morlé L, Kessler P, Wolfrum U, Trottier Y.

Neurobiol Dis. 2015 Aug;80:15-28. doi: 10.1016/j.nbd.2015.05.008. Epub 2015 May 16.

PMID:
25989602
31.

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

Brault V, Duchon A, Romestaing C, Sahun I, Pothion S, Karout M, Borel C, Dembele D, Bizot JC, Messaddeq N, Sharp AJ, Roussel D, Antonarakis SE, Dierssen M, Hérault Y.

PLoS Genet. 2015 Mar 24;11(3):e1005062. doi: 10.1371/journal.pgen.1005062. eCollection 2015 Mar.

32.

The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.

Mlih M, Host L, Martin S, Niederhoffer N, Monassier L, Terrand J, Messaddeq N, Radke M, Gotthardt M, Bruban V, Kober F, Bernard M, Canet-Soulas E, Abt-Jijon F, Boucher P, Matz RL.

J Biol Chem. 2015 Jan 23;290(4):2419-30. doi: 10.1074/jbc.M114.597377. Epub 2014 Dec 8.

33.

Biodistribution of X-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core.

Attia MF, Anton N, Chiper M, Akasov R, Anton H, Messaddeq N, Fournel S, Klymchenko AS, Mély Y, Vandamme TF.

ACS Nano. 2014 Oct 28;8(10):10537-50. doi: 10.1021/nn503973z. Epub 2014 Oct 10.

PMID:
25284066
34.

Microfluidic conceived drug loaded Janus particles in side-by-side capillaries device.

Khan IU, Serra CA, Anton N, Li X, Akasov R, Messaddeq N, Kraus I, Vandamme TF.

Int J Pharm. 2014 Oct 1;473(1-2):239-49. doi: 10.1016/j.ijpharm.2014.06.035. Epub 2014 Jun 19.

PMID:
24954724
35.

Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia.

Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, Crystal RG, Aubourg P, Puccio H.

Nat Med. 2014 May;20(5):542-7. doi: 10.1038/nm.3510. Epub 2014 Apr 6.

PMID:
24705334
36.

Poly-ε-caprolactone tungsten oxide nanoparticles as a contrast agent for X-ray computed tomography.

Jakhmola A, Anton N, Anton H, Messaddeq N, Hallouard F, Klymchenko A, Mely Y, Vandamme TF.

Biomaterials. 2014 Mar;35(9):2981-6. doi: 10.1016/j.biomaterials.2013.12.032. Epub 2014 Jan 3.

PMID:
24393266
37.

Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity.

Szatkowski C, Vallet J, Dormishian M, Messaddeq N, Valet P, Boulberdaa M, Metzger D, Chambon P, Nebigil CG.

PLoS One. 2013 Dec 4;8(12):e81175. doi: 10.1371/journal.pone.0081175. eCollection 2013.

38.

Prokineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions.

Dormishian M, Turkeri G, Urayama K, Nguyen TL, Boulberdaa M, Messaddeq N, Renault G, Henrion D, Nebigil CG.

J Am Heart Assoc. 2013 Oct 23;2(5):e000411. doi: 10.1161/JAHA.113.000411.

39.

An integrated diagnosis strategy for congenital myopathies.

Böhm J, Vasli N, Malfatti E, Le Gras S, Feger C, Jost B, Monnier N, Brocard J, Karasoy H, Gérard M, Walter MC, Reilich P, Biancalana V, Kretz C, Messaddeq N, Marty I, Lunardi J, Romero NB, Laporte J.

PLoS One. 2013 Jun 24;8(6):e67527. doi: 10.1371/journal.pone.0067527. Print 2013.

40.

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.

Al-Qusairi L, Prokic I, Amoasii L, Kretz C, Messaddeq N, Mandel JL, Laporte J.

FASEB J. 2013 Aug;27(8):3384-94. doi: 10.1096/fj.12-220947. Epub 2013 May 21.

PMID:
23695157
41.

Retinoic acid deficiency impairs the vestibular function.

Romand R, Krezel W, Beraneck M, Cammas L, Fraulob V, Messaddeq N, Kessler P, Hashino E, Dollé P.

J Neurosci. 2013 Mar 27;33(13):5856-66. doi: 10.1523/JNEUROSCI.4618-12.2013.

42.

A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substrates.

Yefimova MG, Messaddeq N, Harnois T, Meunier AC, Clarhaut J, Noblanc A, Weickert JL, Cantereau A, Philippe M, Bourmeyster N, Benzakour O.

Autophagy. 2013 May;9(5):653-66. doi: 10.4161/auto.23839. Epub 2013 Feb 25.

43.

Site-specific Mtm1 mutagenesis by an AAV-Cre vector reveals that myotubularin is essential in adult muscle.

Joubert R, Vignaud A, Le M, Moal C, Messaddeq N, Buj-Bello A.

Hum Mol Genet. 2013 May 1;22(9):1856-66. doi: 10.1093/hmg/ddt038. Epub 2013 Feb 5.

PMID:
23390130
44.

Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia.

Hick A, Wattenhofer-Donzé M, Chintawar S, Tropel P, Simard JP, Vaucamps N, Gall D, Lambot L, André C, Reutenauer L, Rai M, Teletin M, Messaddeq N, Schiffmann SN, Viville S, Pearson CE, Pandolfo M, Puccio H.

Dis Model Mech. 2013 May;6(3):608-21. doi: 10.1242/dmm.010900. Epub 2012 Nov 7.

45.

Iodinated α-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging.

Li X, Anton N, Zuber G, Zhao M, Messaddeq N, Hallouard F, Fessi H, Vandamme TF.

Biomaterials. 2013 Jan;34(2):481-91. doi: 10.1016/j.biomaterials.2012.09.026. Epub 2012 Oct 16.

PMID:
23083930
46.

BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response.

Marion V, Mockel A, De Melo C, Obringer C, Claussmann A, Simon A, Messaddeq N, Durand M, Dupuis L, Loeffler JP, King P, Mutter-Schmidt C, Petrovsky N, Stoetzel C, Dollfus H.

Cell Metab. 2012 Sep 5;16(3):363-77. doi: 10.1016/j.cmet.2012.08.005.

47.

Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia.

Martelli A, Friedman LS, Reutenauer L, Messaddeq N, Perlman SL, Lynch DR, Fedosov K, Schulz JB, Pandolfo M, Puccio H.

Dis Model Mech. 2012 Nov;5(6):860-9. doi: 10.1242/dmm.009829. Epub 2012 Jun 26.

48.

Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.

Dowling JJ, Joubert R, Low SE, Durban AN, Messaddeq N, Li X, Dulin-Smith AN, Snyder AD, Marshall ML, Marshall JT, Beggs AH, Buj-Bello A, Pierson CR.

Dis Model Mech. 2012 Nov;5(6):852-9. doi: 10.1242/dmm.009746. Epub 2012 May 24.

49.

Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle.

Hnia K, Kretz C, Amoasii L, Böhm J, Liu X, Messaddeq N, Qu CK, Laporte J.

Adv Biol Regul. 2012 Jan;52(1):98-107. No abstract available.

PMID:
21930146
50.

Microencapsulation of nanoemulsions: novel Trojan particles for bioactive lipid molecule delivery.

Li X, Anton N, Ta TM, Zhao M, Messaddeq N, Vandamme TF.

Int J Nanomedicine. 2011;6:1313-25. doi: 10.2147/IJN.S20353. Epub 2011 Jun 24.

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