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Items: 1 to 50 of 86

1.

Correction for Deng et al., "HMGN1 Modulates Nucleosome Occupancy and DNase I Hypersensitivity at the CpG Island Promoters of Embryonic Stem Cells".

Deng T, Zhu ZI, Zhang S, Leng F, Cherukuri S, Hansen L, Mariño-Ramírez L, Meshorer E, Landsman D, Bustin M.

Mol Cell Biol. 2018 May 29;38(12). pii: e00185-18. doi: 10.1128/MCB.00185-18. Print 2018 Jun 15. No abstract available.

2.

PARP1-dependent eviction of the linker histone H1 mediates immediate early gene expression during neuronal activation.

Azad GK, Ito K, Sailaja BS, Biran A, Nissim-Rafinia M, Yamada Y, Brown DT, Takizawa T, Meshorer E.

J Cell Biol. 2018 Feb 5;217(2):473-481. doi: 10.1083/jcb.201703141. Epub 2017 Dec 28.

3.

A hyperdynamic H3.3 nucleosome marks promoter regions in pluripotent embryonic stem cells.

Schlesinger S, Kaffe B, Melcer S, Aguilera JD, Sivaraman DM, Kaplan T, Meshorer E.

Nucleic Acids Res. 2017 Dec 1;45(21):12181-12194. doi: 10.1093/nar/gkx817.

4.

An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells.

Harikumar A, Edupuganti RR, Sorek M, Azad GK, Markoulaki S, Sehnalová P, Legartová S, Bártová E, Farkash-Amar S, Jaenisch R, Alon U, Meshorer E.

Stem Cell Reports. 2017 Oct 10;9(4):1304-1314. doi: 10.1016/j.stemcr.2017.08.022. Epub 2017 Sep 28.

5.

Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation.

Edupuganti RR, Harikumar A, Aaronson Y, Biran A, Sailaja BS, Nissim-Rafinia M, Azad GK, Cohen MA, Park JE, Shivalila CS, Markoulaki S, Sze SK, Jaenisch R, Meshorer E.

Stem Cell Reports. 2017 Oct 10;9(4):1291-1303. doi: 10.1016/j.stemcr.2017.08.021. Epub 2017 Sep 28.

6.

The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity.

Torres CM, Biran A, Burney MJ, Patel H, Henser-Brownhill T, Cohen AS, Li Y, Ben-Hamo R, Nye E, Spencer-Dene B, Chakravarty P, Efroni S, Matthews N, Misteli T, Meshorer E, Scaffidi P.

Science. 2016 Sep 30;353(6307). pii: aaf1644. doi: 10.1126/science.aaf1644.

7.

Systematic identification of gene family regulators in mouse and human embryonic stem cells.

Aaronson Y, Livyatan I, Gokhman D, Meshorer E.

Nucleic Acids Res. 2016 May 19;44(9):4080-9. doi: 10.1093/nar/gkw259. Epub 2016 Apr 15.

8.

Epigenetics: It's Getting Old. Past Meets Future in Paleoepigenetics.

Gokhman D, Meshorer E, Carmel L.

Trends Ecol Evol. 2016 Apr;31(4):290-300. doi: 10.1016/j.tree.2016.01.010. Epub 2016 Feb 15. Review.

PMID:
26898827
9.

BindDB: An Integrated Database and Webtool Platform for "Reverse-ChIP" Epigenomic Analysis.

Livyatan I, Aaronson Y, Gokhman D, Ashkenazi R, Meshorer E.

Cell Stem Cell. 2015 Dec 3;17(6):647-648. doi: 10.1016/j.stem.2015.11.015. No abstract available.

10.

Chromatin remodeling and bivalent histone modifications in embryonic stem cells.

Harikumar A, Meshorer E.

EMBO Rep. 2015 Dec;16(12):1609-19. doi: 10.15252/embr.201541011. Epub 2015 Nov 9. Review.

11.

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.

Mattout A, Aaronson Y, Sailaja BS, Raghu Ram EV, Harikumar A, Mallm JP, Sim KH, Nissim-Rafinia M, Supper E, Singh PB, Sze SK, Gasser SM, Rippe K, Meshorer E.

Genome Biol. 2015 Sep 28;16:213. doi: 10.1186/s13059-015-0760-8.

12.

SF3B1 association with chromatin determines splicing outcomes.

Kfir N, Lev-Maor G, Glaich O, Alajem A, Datta A, Sze SK, Meshorer E, Ast G.

Cell Rep. 2015 Apr 28;11(4):618-29. doi: 10.1016/j.celrep.2015.03.048. Epub 2015 Apr 16.

13.

Differential association of chromatin proteins identifies BAF60a/SMARCD1 as a regulator of embryonic stem cell differentiation.

Alajem A, Biran A, Harikumar A, Sailaja BS, Aaronson Y, Livyatan I, Nissim-Rafinia M, Sommer AG, Mostoslavsky G, Gerbasi VR, Golden DE, Datta A, Sze SK, Meshorer E.

Cell Rep. 2015 Mar 31;10(12):2019-31. doi: 10.1016/j.celrep.2015.02.064. Epub 2015 Mar 26.

14.

Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

Moussaieff A, Rouleau M, Kitsberg D, Cohen M, Levy G, Barasch D, Nemirovski A, Shen-Orr S, Laevsky I, Amit M, Bomze D, Elena-Herrmann B, Scherf T, Nissim-Rafinia M, Kempa S, Itskovitz-Eldor J, Meshorer E, Aberdam D, Nahmias Y.

Cell Metab. 2015 Mar 3;21(3):392-402. doi: 10.1016/j.cmet.2015.02.002.

15.

HP1 is involved in regulating the global impact of DNA methylation on alternative splicing.

Yearim A, Gelfman S, Shayevitch R, Melcer S, Glaich O, Mallm JP, Nissim-Rafinia M, Cohen AH, Rippe K, Meshorer E, Ast G.

Cell Rep. 2015 Feb 24;10(7):1122-34. doi: 10.1016/j.celrep.2015.01.038. Epub 2015 Feb 19.

16.

Transcription factors bind negatively selected sites within human mtDNA genes.

Blumberg A, Sri Sailaja B, Kundaje A, Levin L, Dadon S, Shmorak S, Shaulian E, Meshorer E, Mishmar D.

Genome Biol Evol. 2014 Sep 22;6(10):2634-46. doi: 10.1093/gbe/evu210.

17.

Stem cell epigenetics: looking forward.

Benitah SA, Bracken A, Dou Y, Huangfu D, Ivanova N, Koseki H, Laurent L, Lim DA, Meshorer E, Pombo A, Sander M, Xu GL.

Cell Stem Cell. 2014 Jun 5;14(6):706-9. No abstract available.

18.

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.

Alvarez-Saavedra M, De Repentigny Y, Lagali PS, Raghu Ram EV, Yan K, Hashem E, Ivanochko D, Huh MS, Yang D, Mears AJ, Todd MA, Corcoran CP, Bassett EA, Tokarew NJ, Kokavec J, Majumder R, Ioshikhes I, Wallace VA, Kothary R, Meshorer E, Stopka T, Skoultchi AI, Picketts DJ.

Nat Commun. 2014 Jun 20;5:4181. doi: 10.1038/ncomms5181.

19.

PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.

Raviv S, Bharti K, Rencus-Lazar S, Cohen-Tayar Y, Schyr R, Evantal N, Meshorer E, Zilberberg A, Idelson M, Reubinoff B, Grebe R, Rosin-Arbesfeld R, Lauderdale J, Lutty G, Arnheiter H, Ashery-Padan R.

PLoS Genet. 2014 May 29;10(5):e1004360. doi: 10.1371/journal.pgen.1004360. eCollection 2014.

20.

Higher chromatin mobility supports totipotency and precedes pluripotency in vivo.

Bošković A, Eid A, Pontabry J, Ishiuchi T, Spiegelhalter C, Raghu Ram EV, Meshorer E, Torres-Padilla ME.

Genes Dev. 2014 May 15;28(10):1042-7. doi: 10.1101/gad.238881.114.

21.

Reconstructing the DNA methylation maps of the Neandertal and the Denisovan.

Gokhman D, Lavi E, Prüfer K, Fraga MF, Riancho JA, Kelso J, Pääbo S, Meshorer E, Carmel L.

Science. 2014 May 2;344(6183):523-7. doi: 10.1126/science.1250368. Epub 2014 Apr 17.

22.

Asynchronous transcriptional silencing of individual retroviral genomes in embryonic cells.

Schlesinger S, Meshorer E, Goff SP.

Retrovirology. 2014 Apr 17;11:31. doi: 10.1186/1742-4690-11-31.

23.

Systems analysis utilising pathway interactions identifies sonic hedgehog pathway as a primary biomarker and oncogenic target in hepatocellular carcinoma.

Efroni S, Meerzaman D, Schaefer CF, Greenblum S, Soo-Lyu M, Hu Y, Cultraro C, Meshorer E, Buetow KH.

IET Syst Biol. 2013 Dec;7(6):243-51.

PMID:
24712101
24.

Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors.

Ben-David U, Biran A, Scaffidi P, Herold-Mende C, Boehringer M, Meshorer E, Benvenisty N.

J Mol Cell Biol. 2014 Jun;6(3):267-9. doi: 10.1093/jmcb/mju012. Epub 2014 Mar 27. No abstract available.

25.

A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair.

Shahar OD, Kalousi A, Eini L, Fisher B, Weiss A, Darr J, Mazina O, Bramson S, Kupiec M, Eden A, Meshorer E, Mazin AV, Brino L, Goldberg M, Soutoglou E.

Nucleic Acids Res. 2014 May;42(9):5689-701. doi: 10.1093/nar/gku217. Epub 2014 Mar 25.

26.

Genes related to differentiation are correlated with the gene regulatory network structure.

Bodaker M, Meshorer E, Mitrani E, Louzoun Y.

Bioinformatics. 2014 Feb 1;30(3):406-13. doi: 10.1093/bioinformatics/btt685. Epub 2013 Dec 12.

PMID:
24336647
27.

SON sheds light on RNA splicing and pluripotency.

Livyatan I, Meshorer E.

Nat Cell Biol. 2013 Oct;15(10):1139-40. doi: 10.1038/ncb2851.

PMID:
24084863
28.

Measuring the dynamics of chromatin proteins during differentiation.

Harikumar A, Meshorer E.

Methods Mol Biol. 2013;1042:173-80. doi: 10.1007/978-1-62703-526-2_12.

PMID:
23980007
29.

HMGN1 modulates nucleosome occupancy and DNase I hypersensitivity at the CpG island promoters of embryonic stem cells.

Deng T, Zhu ZI, Zhang S, Leng F, Cherukuri S, Hansen L, Mariño-Ramírez L, Meshorer E, Landsman D, Bustin M.

Mol Cell Biol. 2013 Aug;33(16):3377-89. doi: 10.1128/MCB.00435-13. Epub 2013 Jun 17. Erratum in: Mol Cell Biol. 2018 May 29;38(12):.

30.

The HDAC interaction network.

Livyatan I, Meshorer E.

Mol Syst Biol. 2013;9:671. doi: 10.1038/msb.2013.33. No abstract available.

31.

Stem cells: Regulation by alternative splicing.

Aaronson Y, Meshorer E.

Nature. 2013 Jun 13;498(7453):176-7. doi: 10.1038/nature12253. Epub 2013 Jun 5. No abstract available.

PMID:
23739330
32.

Non-polyadenylated transcription in embryonic stem cells reveals novel non-coding RNA related to pluripotency and differentiation.

Livyatan I, Harikumar A, Nissim-Rafinia M, Duttagupta R, Gingeras TR, Meshorer E.

Nucleic Acids Res. 2013 Jul;41(12):6300-15. doi: 10.1093/nar/gkt316. Epub 2013 Apr 29.

33.

Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells.

Sommer CA, Christodoulou C, Gianotti-Sommer A, Shen SS, Sailaja BS, Hezroni H, Spira A, Meshorer E, Kotton DN, Mostoslavsky G.

PLoS One. 2012;7(12):e51711. doi: 10.1371/journal.pone.0051711. Epub 2012 Dec 14.

34.

Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4.

Sailaja BS, Cohen-Carmon D, Zimmerman G, Soreq H, Meshorer E.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3687-95. doi: 10.1073/pnas.1209990110. Epub 2012 Dec 10.

35.

Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones.

Gokhman D, Livyatan I, Sailaja BS, Melcer S, Meshorer E.

Nat Struct Mol Biol. 2013 Jan;20(1):119-26. doi: 10.1038/nsmb.2448. Epub 2012 Dec 9.

PMID:
23222641
36.

Systematic determination of replication activity type highlights interconnections between replication, chromatin structure and nuclear localization.

Farkash-Amar S, David Y, Polten A, Hezroni H, Eldar YC, Meshorer E, Yakhini Z, Simon I.

PLoS One. 2012;7(11):e48986. doi: 10.1371/journal.pone.0048986. Epub 2012 Nov 7.

37.

Polyglutamine (polyQ) disorders: the chromatin connection.

Cohen-Carmon D, Meshorer E.

Nucleus. 2012 Sep-Oct;3(5):433-41. doi: 10.4161/nucl.21481. Epub 2012 Aug 15. Review.

38.

Elucidating the temporal dynamics of chromatin-associated protein release upon DNA digestion by quantitative proteomic approach.

Dutta B, Adav SS, Koh CG, Lim SK, Meshorer E, Sze SK.

J Proteomics. 2012 Sep 18;75(17):5493-506. doi: 10.1016/j.jprot.2012.06.030. Epub 2012 Jul 13.

PMID:
22796351
39.

Concise review: chromatin and genome organization in reprogramming.

Biran A, Meshorer E.

Stem Cells. 2012 Sep;30(9):1793-9. doi: 10.1002/stem.1169. Review.

40.

Histone modifications and lamin A regulate chromatin protein dynamics in early embryonic stem cell differentiation.

Melcer S, Hezroni H, Rand E, Nissim-Rafinia M, Skoultchi A, Stewart CL, Bustin M, Meshorer E.

Nat Commun. 2012 Jun 19;3:910. doi: 10.1038/ncomms1915.

41.

Chromatin immunoprecipitation in mouse hippocampal cells and tissues.

Sailaja BS, Takizawa T, Meshorer E.

Methods Mol Biol. 2012;809:353-64. doi: 10.1007/978-1-61779-376-9_24.

PMID:
22113288
42.

Live imaging of induced and controlled DNA double-strand break formation reveals extremely low repair by homologous recombination in human cells.

Shahar OD, Raghu Ram EV, Shimshoni E, Hareli S, Meshorer E, Goldberg M.

Oncogene. 2012 Jul 26;31(30):3495-504. doi: 10.1038/onc.2011.516. Epub 2011 Nov 21.

PMID:
22105360
43.

Global epigenetic changes during somatic cell reprogramming to iPS cells.

Mattout A, Biran A, Meshorer E.

J Mol Cell Biol. 2011 Dec;3(6):341-50. doi: 10.1093/jmcb/mjr028. Epub 2011 Nov 1.

PMID:
22044880
44.

H3K9 histone acetylation predicts pluripotency and reprogramming capacity of ES cells.

Hezroni H, Tzchori I, Davidi A, Mattout A, Biran A, Nissim-Rafinia M, Westphal H, Meshorer E.

Nucleus. 2011 Jul-Aug;2(4):300-9. doi: 10.4161/nucl.2.4.16767. Epub 2011 Jul 1.

45.

Pluripotency-related, valproic acid (VPA)-induced genome-wide histone H3 lysine 9 (H3K9) acetylation patterns in embryonic stem cells.

Hezroni H, Sailaja BS, Meshorer E.

J Biol Chem. 2011 Oct 14;286(41):35977-88. doi: 10.1074/jbc.M111.266254. Epub 2011 Aug 17.

46.

Nuclear visions enhanced: chromatin structure, organization and dynamics.

Meshorer E, Herrmann H, Raška I.

EMBO Rep. 2011 Jul 15;12(8):748-50. doi: 10.1038/embor.2011.148.

47.

Photobleaching assays (FRAP & FLIP) to measure chromatin protein dynamics in living embryonic stem cells.

Nissim-Rafinia M, Meshorer E.

J Vis Exp. 2011 Jun 29;(52). pii: 2696. doi: 10.3791/2696.

48.

Open chromatin in pluripotency and reprogramming.

Gaspar-Maia A, Alajem A, Meshorer E, Ramalho-Santos M.

Nat Rev Mol Cell Biol. 2011 Jan;12(1):36-47. doi: 10.1038/nrm3036. Review. Erratum in: Nat Rev Mol Cell Biol. 2011 Apr;12(4):273.

49.

Chromatin plasticity in pluripotent cells.

Melcer S, Meshorer E.

Essays Biochem. 2010 Sep 20;48(1):245-62. doi: 10.1042/bse0480245. Review.

PMID:
20822497
50.

Imaging chromatin in embryonic stem cells.

Meshorer E.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2008 Jul 11.

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