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Items: 7

1.

Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib).

Germann UA, Furey BF, Markland W, Hoover RR, Aronov AM, Roix JJ, Hale M, Boucher DM, Sorrell DA, Martinez-Botella G, Fitzgibbon M, Shapiro P, Wick MJ, Samadani R, Meshaw K, Groover A, DeCrescenzo G, Namchuk M, Emery CM, Saha S, Welsch DJ.

Mol Cancer Ther. 2017 Nov;16(11):2351-2363. doi: 10.1158/1535-7163.MCT-17-0456. Epub 2017 Sep 22.

2.

Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin.

Hall JC, Marlow LA, Mathias AC, Dawson LK, Durham WF, Meshaw KA, Mullin RJ, Synnott AJ, Small DL, Krishna M, von Hoff D, Schüler J, Hart SN, Couch FJ, Colon-Otero G, Copland JA.

J Transl Med. 2016 May 10;14(1):129. doi: 10.1186/s12967-016-0875-z.

3.

Systematic repurposing screening in xenograft models identifies approved drugs with novel anti-cancer activity.

Roix JJ, Harrison SD, Rainbolt EA, Meshaw KR, McMurry AS, Cheung P, Saha S.

PLoS One. 2014 Aug 5;9(8):e101708. doi: 10.1371/journal.pone.0101708. eCollection 2014.

4.

Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.

Kirane A, Toombs JE, Larsen JE, Ostapoff KT, Meshaw KR, Zaknoen S, Brekken RA, Burrows FJ.

Carcinogenesis. 2012 Sep;33(9):1639-46. doi: 10.1093/carcin/bgs195. Epub 2012 Jun 7.

5.

Immunotoxicologic effects of cyclosporine on tumor progression in models of squamous cell carcinoma and B-cell lymphoma in C3H mice.

Rafferty P, Egenolf D, Brosnan K, Makropoulos D, Jordan J, Meshaw K, Walker M, Volk A, Bugelski PJ.

J Immunotoxicol. 2012 Jan-Mar;9(1):43-55. doi: 10.3109/1547691X.2011.614646.

PMID:
22299716
6.

Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen.

Gelman MS, Ye XK, Stull R, Suhy D, Jin L, Ng D, Than B, Ji M, Pan A, Perez P, Sun Y, Yeung P, Garcia LM, Harte R, Lu Y, Lamar E, Tavassoli R, Kennedy S, Osborn S, Chin DJ, Meshaw K, Holzmayer TA, Axenovich SA, Abo A.

Oncogene. 2004 Oct 21;23(49):8158-70.

PMID:
15361835
7.

Alpha-lactalbumin as a modulator of mammary cellular activity.

Alston-Mills B, Hepler CD, Sternhagen L, Allen JC, Meshaw KA.

In Vitro Cell Dev Biol Anim. 1998 Nov-Dec;34(10):747-50. No abstract available.

PMID:
9870521

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