Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 271

1.

Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site.

Selberg S, Blokhina D, Aatonen M, Koivisto P, Siltanen A, Mervaala E, Kankuri E, Karelson M.

Cell Rep. 2019 Mar 26;26(13):3762-3771.e5. doi: 10.1016/j.celrep.2019.02.100.

2.

Increase in Body Mass Index Decreases Duration of Apneas and Hypopneas in Obstructive Sleep Apnea.

Leppänen T, Kulkas A, Mervaala E, Töyräs J.

Respir Care. 2019 Jan;64(1):77-84. doi: 10.4187/respcare.06297.

PMID:
30578359
3.

Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy.

Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J.

EMBO Mol Med. 2019 Jan;11(1). pii: e9456. doi: 10.15252/emmm.201809456.

4.

Required CPAP usage time to normalize AHI in obstructive sleep apnea patients: a simulation study.

Kulkas A, Leppänen T, Nikkonen S, Oksenberg A, Duce B, Mervaala E, Töyräs J.

Physiol Meas. 2018 Nov 28;39(11):115009. doi: 10.1088/1361-6579/aae7fe.

PMID:
30485257
5.

Bayesian Network Model to Evaluate the Effectiveness of Continuous Positive Airway Pressure Treatment of Sleep Apnea.

Ryynänen OP, Leppänen T, Kekolahti P, Mervaala E, Töyräs J.

Healthc Inform Res. 2018 Oct;24(4):346-358. doi: 10.4258/hir.2018.24.4.346. Epub 2018 Oct 31.

6.

Bifrontal active and sham rTMS in treatment-resistant unipolar major depression.

Valkonen-Korhonen M, Leinola H, Könönen M, Niskanen E, Purhonen M, Pakarinen M, Ruusunen A, Lehto SM, Mervaala E, Honkalampi K, Koivumaa-Honkanen H, Viinamäki H.

Nord J Psychiatry. 2018 Nov;72(8):586-592. doi: 10.1080/08039488.2018.1500640. Epub 2018 Oct 23.

PMID:
30348049
7.

Differences in arousal probability and duration after apnea and hypopnea events in adult obstructive sleep apnea patients.

Leppänen T, Kulkas A, Oksenberg A, Duce B, Mervaala E, Töyräs J.

Physiol Meas. 2018 Nov 6;39(11):114004. doi: 10.1088/1361-6579/aae42c.

PMID:
30251964
8.

Targeting β1-integrin inhibits vascular leakage in endotoxemia.

Hakanpaa L, Kiss EA, Jacquemet G, Miinalainen I, Lerche M, Guzmán C, Mervaala E, Eklund L, Ivaska J, Saharinen P.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6467-E6476. doi: 10.1073/pnas.1722317115. Epub 2018 Jun 25.

9.

Abnormal motor cortical adaptation to external stimulus in Unverricht-Lundborg disease (progressive myoclonus type 1, EPM1).

Julkunen P, Löfberg O, Kallioniemi E, Hyppönen J, Kälviäinen R, Mervaala E.

J Neurophysiol. 2018 Aug 1;120(2):617-623. doi: 10.1152/jn.00063.2018. Epub 2018 May 9.

PMID:
29742025
10.

Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach.

Lalowski MM, Björk S, Finckenberg P, Soliymani R, Tarkia M, Calza G, Blokhina D, Tulokas S, Kankainen M, Lakkisto P, Baumann M, Kankuri E, Mervaala E.

Front Physiol. 2018 Apr 11;9:365. doi: 10.3389/fphys.2018.00365. eCollection 2018.

11.

Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes.

Björk S, Ojala EA, Nordström T, Ahola A, Liljeström M, Hyttinen J, Kankuri E, Mervaala E.

Front Physiol. 2017 Nov 2;8:884. doi: 10.3389/fphys.2017.00884. eCollection 2017.

12.

Severity of individual obstruction events increases with age in patients with obstructive sleep apnea.

Leppänen T, Töyräs J, Mervaala E, Penzel T, Kulkas A.

Sleep Med. 2017 Sep;37:32-37. doi: 10.1016/j.sleep.2017.06.004. Epub 2017 Jun 24.

PMID:
28899537
13.

Success Rate and Technical Quality of Home Polysomnography With Self-Applicable Electrode Set in Subjects With Possible Sleep Bruxism.

Miettinen T, Myllymaa K, Westeren-Punnonen S, Ahlberg J, Hukkanen T, Toyras J, Lappalainen R, Mervaala E, Sipila K, Myllymaa S, Miettinen T, Myllymaa K, Westeren-Punnonen S, Ahlberg J, Hukkanen T, Toyras J, Lappalainen R, Mervaala E, Sipila K, Myllymaa S.

IEEE J Biomed Health Inform. 2018 Jul;22(4):1124-1132. doi: 10.1109/JBHI.2017.2741522. Epub 2017 Aug 18.

PMID:
28829322
14.

Age-related changes of cortical excitability and connectivity in healthy humans: non-invasive evaluation of sensorimotor network by means of TMS-EEG.

Ferreri F, Guerra A, Vollero L, Ponzo D, Maatta S, Mervaala E, Iannello G, Di Lazzaro V.

Neuroscience. 2017 Aug 15;357:255-263. doi: 10.1016/j.neuroscience.2017.06.014. Epub 2017 Jun 15.

PMID:
28624571
15.

Peri-apneic hemodynamic reactions in obstructive sleep apnea.

Muraja-Murro A, Nieminen O, Julkunen P, Töyräs J, Laitinen T, Mervaala E.

Pathophysiology. 2017 Sep;24(3):197-203. doi: 10.1016/j.pathophys.2017.05.003. Epub 2017 May 31.

PMID:
28601366
16.

Screen-printed ambulatory electrode set enables accurate diagnostics of sleep bruxism.

Miettinen T, Myllymaa K, Muraja-Murro A, Westeren-Punnonen S, Hukkanen T, Töyräs J, Lappalainen R, Mervaala E, Sipilä K, Myllymaa S.

J Sleep Res. 2018 Feb;27(1):103-112. doi: 10.1111/jsr.12536. Epub 2017 May 17.

17.

Alternative interpretation of data for recommendations on how to manage rheumatoid arthritis.

Pirilä L, Sokka T, Kauppi MJ, Rantalaiho VM, Mervaala E, Puolakka K.

Ann Rheum Dis. 2017 Dec;76(12):e49. doi: 10.1136/annrheumdis-2017-211505. Epub 2017 Apr 27. No abstract available.

PMID:
28450311
18.

The effect of 50% compared to 100% inspired oxygen fraction on brain oxygenation and post cardiac arrest mitochondrial function in experimental cardiac arrest.

Nelskylä A, Nurmi J, Jousi M, Schramko A, Mervaala E, Ristagno G, Skrifvars MB.

Resuscitation. 2017 Jul;116:1-7. doi: 10.1016/j.resuscitation.2017.04.022. Epub 2017 Apr 22.

PMID:
28438718
19.

Age related differences in functional synchronization of EEG activity as evaluated by means of TMS-EEG coregistrations.

Ferreri F, Vecchio F, Guerra A, Miraglia F, Ponzo D, Vollero L, Iannello G, Maatta S, Mervaala E, Rossini PM, Di Lazzaro V.

Neurosci Lett. 2017 Apr 24;647:141-146. doi: 10.1016/j.neulet.2017.03.021. Epub 2017 Mar 18.

PMID:
28323091
20.

Severity of individual obstruction events is gender dependent in sleep apnea.

Leppänen T, Kulkas A, Duce B, Mervaala E, Töyräs J.

Sleep Breath. 2017 May;21(2):397-404. doi: 10.1007/s11325-016-1430-0. Epub 2016 Dec 13.

PMID:
27966055
21.

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection.

Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13144-13149. Epub 2016 Oct 31.

22.

Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes.

Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ.

Sci Rep. 2016 Sep 26;6:32695. doi: 10.1038/srep32695.

23.

Unverricht-Lundborg disease.

Crespel A, Ferlazzo E, Franceschetti S, Genton P, Gouider R, Kälviäinen R, Korja M, Lehtinen MK, Mervaala E, Simonato M, Vaarmann A.

Epileptic Disord. 2016 Sep 1;18(S2):28-37. Review.

PMID:
27582036
24.

Assessment of the suitability of using a forehead EEG electrode set and chin EMG electrodes for sleep staging in polysomnography.

Myllymaa S, Muraja-Murro A, Westeren-Punnonen S, Hukkanen T, Lappalainen R, Mervaala E, Töyräs J, Sipilä K, Myllymaa K.

J Sleep Res. 2016 Dec;25(6):636-645. doi: 10.1111/jsr.12425. Epub 2016 May 27.

25.

The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs.

Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH.

Hum Exp Toxicol. 2017 Apr;36(4):365-375. doi: 10.1177/0960327116650010. Epub 2016 May 24.

PMID:
27222493
26.

Length of Individual Apnea Events Is Increased by Supine Position and Modulated by Severity of Obstructive Sleep Apnea.

Leppänen T, Töyräs J, Muraja-Murro A, Kupari S, Tiihonen P, Mervaala E, Kulkas A.

Sleep Disord. 2016;2016:9645347. doi: 10.1155/2016/9645347. Epub 2016 Mar 9.

27.

RemLogic plug-in enables clinical application of apnea-hypopnea index adjusted for severity of individual obstruction events.

Leppänen T, Särkkä M, Kulkas A, Muraja-Murro A, Kupari S, Anttonen M, Tiihonen P, Mervaala E, Töyräs J.

J Med Eng Technol. 2016;40(3):119-26. doi: 10.3109/03091902.2016.1148791. Epub 2016 Mar 15.

PMID:
26977739
28.

Sensorimotor cortex excitability and connectivity in Alzheimer's disease: A TMS-EEG Co-registration study.

Ferreri F, Vecchio F, Vollero L, Guerra A, Petrichella S, Ponzo D, Määtta S, Mervaala E, Könönen M, Ursini F, Pasqualetti P, Iannello G, Rossini PM, Di Lazzaro V.

Hum Brain Mapp. 2016 Jun;37(6):2083-96. doi: 10.1002/hbm.23158. Epub 2016 Mar 4.

PMID:
26945686
29.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
30.

Rational Autologous Cell Sources For Therapy of Heart Failure - Vehicles and Targets For Gene and RNA Therapies.

Lampinen M, Vento A, Laurikka J, Nystedt J, Mervaala E, Harjula A, Kankuri E.

Curr Gene Ther. 2016;16(1):21-33. Review.

PMID:
26725880
31.

Mitochondrial respiratory dysfunction due to the conversion of substituted cathinones to methylbenzamides in SH-SY5Y cells.

den Hollander B, Sundström M, Pelander A, Siltanen A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E.

Sci Rep. 2015 Oct 14;5:14924. doi: 10.1038/srep14924.

32.

Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling.

Holopainen T, Räsänen M, Anisimov A, Tuomainen T, Zheng W, Tvorogov D, Hulmi JJ, Andersson LC, Cenni B, Tavi P, Mervaala E, Kivelä R, Alitalo K.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13063-8. doi: 10.1073/pnas.1517810112. Epub 2015 Oct 1.

33.

Temporal anteroinferior encephalocele: An underrecognized etiology of temporal lobe epilepsy?

Saavalainen T, Jutila L, Mervaala E, Kälviäinen R, Vanninen R, Immonen A.

Neurology. 2015 Oct 27;85(17):1467-74. doi: 10.1212/WNL.0000000000002062. Epub 2015 Sep 25.

PMID:
26408489
34.

Locating and Outlining the Cortical Motor Representation Areas of Facial Muscles With Navigated Transcranial Magnetic Stimulation.

Säisänen L, Julkunen P, Kemppainen S, Danner N, Immonen A, Mervaala E, Määttä S, Muraja-Murro A, Könönen M.

Neurosurgery. 2015 Sep;77(3):394-405; discussion 405. doi: 10.1227/NEU.0000000000000798.

PMID:
26035404
35.

Forehead EEG electrode set versus full-head scalp EEG in 100 patients with altered mental state.

Muraja-Murro A, Mervaala E, Westeren-Punnonen S, Lepola P, Töyräs J, Myllymaa S, Julkunen P, Kantanen AM, Kälviäinen R, Myllymaa K.

Epilepsy Behav. 2015 Aug;49:245-9. doi: 10.1016/j.yebeh.2015.04.041. Epub 2015 May 18.

PMID:
25997637
36.

Effect of oxygen desaturation threshold on determination of OSA severity during weight loss.

Myllymaa K, Myllymaa S, Leppänen T, Kulkas A, Kupari S, Tiihonen P, Mervaala E, Seppä J, Tuomilehto H, Töyräs J.

Sleep Breath. 2016 Mar;20(1):33-42. doi: 10.1007/s11325-015-1180-4. Epub 2015 Apr 21.

PMID:
25896899
37.

Amount of weight loss or gain influences the severity of respiratory events in sleep apnea.

Kulkas A, Leppänen T, Sahlman J, Tiihonen P, Mervaala E, Kokkarinen J, Randell J, Seppä J, Töyräs J, Tuomilehto H.

Med Biol Eng Comput. 2015 Oct;53(10):975-88. doi: 10.1007/s11517-015-1290-y. Epub 2015 Apr 17.

PMID:
25894465
38.

Comparison of arrhythmogenicity and proinflammatory activity induced by intramyocardial or epicardial myoblast sheet delivery in a rat model of ischemic heart failure.

Pätilä T, Miyagawa S, Imanishi Y, Fukushima S, Siltanen A, Mervaala E, Kankuri E, Harjula A, Sawa Y.

PLoS One. 2015 Apr 10;10(4):e0123963. doi: 10.1371/journal.pone.0123963. eCollection 2015.

39.

Non-invasive mapping of bilateral motor speech areas using navigated transcranial magnetic stimulation and functional magnetic resonance imaging.

Könönen M, Tamsi N, Säisänen L, Kemppainen S, Määttä S, Julkunen P, Jutila L, Äikiä M, Kälviäinen R, Niskanen E, Vanninen R, Karjalainen P, Mervaala E.

J Neurosci Methods. 2015 Jun 15;248:32-40. doi: 10.1016/j.jneumeth.2015.03.030. Epub 2015 Apr 3.

PMID:
25845482
40.

Refining the phenotype of Unverricht-Lundborg disease (EPM1): a population-wide Finnish study.

Hyppönen J, Äikiä M, Joensuu T, Julkunen P, Danner N, Koskenkorva P, Vanninen R, Lehesjoki AE, Mervaala E, Kälviäinen R.

Neurology. 2015 Apr 14;84(15):1529-36. doi: 10.1212/WNL.0000000000001466. Epub 2015 Mar 13.

PMID:
25770194
41.

Reduced cortical activation in inferior frontal junction in Unverricht-Lundborg disease (EPM1) - A motor fMRI study.

Könönen M, Danner N, Koskenkorva P, Kälviäinen R, Hyppönen J, Mervaala E, Karjalainen P, Vanninen R, Niskanen E.

Epilepsy Res. 2015 Mar;111:78-84. doi: 10.1016/j.eplepsyres.2015.01.006. Epub 2015 Jan 24.

PMID:
25769376
42.

Effect of different oxygen desaturation threshold levels on hypopnea scoring and classification of severity of sleep apnea.

Myllymaa S, Myllymaa K, Kupari S, Kulkas A, Leppänen T, Tiihonen P, Mervaala E, Seppä J, Tuomilehto H, Töyräs J.

Sleep Breath. 2015 Sep;19(3):947-54. doi: 10.1007/s11325-015-1118-x. Epub 2015 Jan 22.

PMID:
25604477
43.

A Handy EEG Electrode Set for patients suffering from altered mental state.

Lepola P, Myllymaa S, Töyräs J, Hukkanen T, Mervaala E, Määttä S, Lappalainen R, Myllymaa K.

J Clin Monit Comput. 2015 Dec;29(6):697-705. doi: 10.1007/s10877-014-9652-9. Epub 2015 Jan 10.

PMID:
25575984
44.

Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation.

Kankuri E, Mervaala EE, Storvik M, Ahola AM, Levijoki J, Müller DN, Finckenberg P, Mervaala EM.

Clin Sci (Lond). 2015 Jun;128(11):735-47. doi: 10.1042/CS20140445.

PMID:
25534858
45.

Dexmedetomidine preconditioning ameliorates kidney ischemia-reperfusion injury.

Lempiäinen J, Finckenberg P, Mervaala EE, Storvik M, Kaivola J, Lindstedt K, Levijoki J, Mervaala EM.

Pharmacol Res Perspect. 2014 Jun;2(3):e00045. doi: 10.1002/prp2.45. Epub 2014 Apr 22.

46.

Morbidity and mortality risk ratios are elevated in severe supine dominant OSA: a long-term follow-up study.

Kulkas A, Muraja-Murro A, Tiihonen P, Mervaala E, Töyräs J.

Sleep Breath. 2015 May;19(2):653-60. doi: 10.1007/s11325-014-1071-0. Epub 2014 Nov 1.

PMID:
25367548
47.

Neurophysiological features of motor cortex excitability and plasticity in Subcortical Ischemic Vascular Dementia: a TMS mapping study.

Guerra A, Petrichella S, Vollero L, Ponzo D, Pasqualetti P, Määttä S, Mervaala E, Könönen M, Bressi F, Iannello G, Rossini PM, Ferreri F.

Clin Neurophysiol. 2015 May;126(5):906-13. doi: 10.1016/j.clinph.2014.07.036. Epub 2014 Sep 16.

PMID:
25262646
48.

Weight loss alters severity of individual nocturnal respiratory events depending on sleeping position.

Kulkas A, Leppänen T, Sahlman J, Tiihonen P, Mervaala E, Kokkarinen J, Randell J, Seppä J, Töyräs J, Tuomilehto H.

Physiol Meas. 2014 Oct;35(10):2037-52. doi: 10.1088/0967-3334/35/10/2037. Epub 2014 Sep 19.

PMID:
25237739
49.

Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE).

Jutila L, Aikiä M, Immonen A, Mervaala E, Alafuzoff I, Kälviäinen R.

Epilepsy Res. 2014 Sep;108(7):1228-37. doi: 10.1016/j.eplepsyres.2014.05.002. Epub 2014 May 28.

PMID:
24953384
50.

Keto amphetamine toxicity-focus on the redox reactivity of the cathinone designer drug mephedrone.

den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E.

Toxicol Sci. 2014 Sep;141(1):120-31. doi: 10.1093/toxsci/kfu108. Epub 2014 Jun 9.

Supplemental Content

Loading ...
Support Center