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Items: 1 to 50 of 228

1.

Clinical visible signs of disease activity in vitiligo: a systematic review and meta-analysis.

van Geel N, Grine L, De Wispelaere P, Mertens D, Prinsen CAC, Speeckaert R.

J Eur Acad Dermatol Venereol. 2019 May 26. doi: 10.1111/jdv.15604. [Epub ahead of print] Review.

PMID:
31131483
2.

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.

Mallm JP, Iskar M, Ishaque N, Klett LC, Kugler SJ, Muino JM, Teif VB, Poos AM, Großmann S, Erdel F, Tavernari D, Koser SD, Schumacher S, Brors B, König R, Remondini D, Vingron M, Stilgenbauer S, Lichter P, Zapatka M, Mertens D, Rippe K.

Mol Syst Biol. 2019 May 22;15(5):e8339. doi: 10.15252/msb.20188339.

3.

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.

Scheffold A, Jebaraj BMC, Tausch E, Bloehdorn J, Ghia P, Yahiaoui A, Dolnik A, Blätte TJ, Bullinger L, Dheenadayalan RP, Li L, Schneider C, Chen SS, Chiorazzi N, Dietrich S, Seiffert M, Tannheimer S, Döhner H, Mertens D, Stilgenbauer S.

Blood. 2019 Apr 22. pii: blood.2018881029. doi: 10.1182/blood.2018881029. [Epub ahead of print]

PMID:
31010847
4.

Venetoclax resistance and acquired BCL2 mutations in chronic lymphocytic leukemia.

Tausch E, Close W, Dolnik A, Bloehdorn J, Chyla B, Bullinger L, Döhner H, Mertens D, Stilgenbauer S.

Haematologica. 2019 Apr 19. pii: haematol.2019.222588. doi: 10.3324/haematol.2019.222588. [Epub ahead of print]

5.

Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia.

Jebaraj BMC, Tausch E, Landau DA, Bahlo J, Robrecht S, Taylor-Weiner AN, Bloehdorn J, Scheffold A, Mertens D, Böttcher S, Kneba M, Jäger U, Zenz T, Wenger MK, Fingerle-Rowson G, Wendtner C, Fink AM, Wu CJ, Eichhorst B, Fischer K, Hallek M, Döhner H, Stilgenbauer S.

Leukemia. 2019 Mar 25. doi: 10.1038/s41375-019-0446-4. [Epub ahead of print]

PMID:
30911113
6.

Adult vaccination for pneumococcal disease: a comparison of the national guidelines in Europe.

Bonnave C, Mertens D, Peetermans W, Cobbaert K, Ghesquiere B, Deschodt M, Flamaing J.

Eur J Clin Microbiol Infect Dis. 2019 Apr;38(4):785-791. doi: 10.1007/s10096-019-03485-3. Epub 2019 Feb 18.

PMID:
30778705
7.

FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL.

Close V, Close W, Kugler SJ, Reichenzeller M, Yosifov DY, Bloehdorn J, Pan L, Tausch E, Westhoff MA, Döhner H, Stilgenbauer S, Oswald F, Mertens D.

Blood. 2019 Feb 21;133(8):830-839. doi: 10.1182/blood-2018-09-874529. Epub 2018 Dec 3.

PMID:
30510140
8.
9.

Critical Factors in Determining Fiber Content of Feeds and Foods and Their Ingredients.

Fahey GC Jr, Novotny L, Layton B, Mertens DR.

J AOAC Int. 2018 Aug 2. doi: 10.5740/jaoacint.18-0067. [Epub ahead of print]

PMID:
30071919
10.

Comprehensive microRNA expression profiling in cerebrospinal fluid distinguishes between neurological disease classes.

Grasedieck S, Mulaw M, Sperb N, Wessinger K, Rouhi A, Bommer M, Bromberg JEC, Otto M, Tumani H, von Arnim CAF, Mertens D, Kuchenbauer F.

Neuropathol Appl Neurobiol. 2019 Apr;45(3):318-323. doi: 10.1111/nan.12491. Epub 2018 May 21. No abstract available.

PMID:
29679382
11.

Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach.

Mettang M, Meyer-Pannwitt V, Karpel-Massler G, Zhou S, Carragher NO, Föhr KJ, Baumann B, Nonnenmacher L, Enzenmüller S, Dahlhaus M, Siegelin MD, Stroh S, Mertens D, Fischer-Posovszky P, Schneider EM, Halatsch ME, Debatin KM, Westhoff MA.

Sci Rep. 2018 Apr 3;8(1):5527. doi: 10.1038/s41598-018-23592-z.

12.

A 100-Year Review: Carbohydrates-Characterization, digestion, and utilization.

Hall MB, Mertens DR.

J Dairy Sci. 2017 Dec;100(12):10078-10093. doi: 10.3168/jds.2017-13311. Review.

13.

NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.

Wolf C, Garding A, Filarsky K, Bahlo J, Robrecht S, Becker N, Zucknick M, Rouhi A, Weigel A, Claus R, Weichenhan D, Eichhorst B, Fischer K, Hallek M, Kuchenbauer F, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D.

Int J Cancer. 2018 Jan 15;142(2):322-333. doi: 10.1002/ijc.31057. Epub 2017 Oct 9.

14.

Acute renal failure with need for renal replacement therapy as a complication of zoonotic S. zooepidemicus infection: case report and review of the literature.

Veldeman L, De Wilde K, Vogelaers D, Lerut E, Vonck A, Mertens D, Koch A, Beckers J.

Acta Clin Belg. 2018 Apr;73(2):144-150. doi: 10.1080/17843286.2017.1326547. Epub 2017 May 16. Review.

PMID:
28508721
15.

Ibrutinib-resistant CLL: unwanted and unwonted!

Mertens D, Stilgenbauer S.

Blood. 2017 Mar 16;129(11):1407-1409. doi: 10.1182/blood-2017-01-761536. No abstract available.

16.

Case Study III: The Construction of a Nanotoxicity Database - The MOD-ENP-TOX Experience.

Vriens H, Mertens D, Regret R, Lin P, Locquet JP, Hoet P.

Adv Exp Med Biol. 2017;947:325-344. doi: 10.1007/978-3-319-47754-1_11. Review.

PMID:
28168673
17.

Emergence and analysis of Kuramoto-Sakaguchi-like models as an effective description for the dynamics of coupled Wien-bridge oscillators.

English LQ, Mertens D, Abdoulkary S, Fritz CB, Skowronski K, Kevrekidis PG.

Phys Rev E. 2016 Dec;94(6-1):062212. doi: 10.1103/PhysRevE.94.062212. Epub 2016 Dec 20.

PMID:
28085391
18.

Urbanization drives community shifts towards thermophilic and dispersive species at local and landscape scales.

Piano E, De Wolf K, Bona F, Bonte D, Bowler DE, Isaia M, Lens L, Merckx T, Mertens D, van Kerckvoorde M, De Meester L, Hendrickx F.

Glob Chang Biol. 2017 Jul;23(7):2554-2564. doi: 10.1111/gcb.13606. Epub 2017 Jan 18.

19.

Rapid detection of ATM/p53 function with p27Kip FACS analysis: a novel diagnostic tool for chronic lympocytic leukemia?

Meyer-Pannwitt V, Steinbrecher D, Stilgenbauer S, Mertens D.

Leuk Lymphoma. 2017 Jan;58(1):6-7. Epub 2016 Aug 22. No abstract available.

PMID:
27545008
20.

The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.

Walliser C, Hermkes E, Schade A, Wiese S, Deinzer J, Zapatka M, Désiré L, Mertens D, Stilgenbauer S, Gierschik P.

J Biol Chem. 2016 Oct 14;291(42):22136-22148. Epub 2016 Aug 19.

21.

Assumptions at the philosophical and programmatic levels in evaluation.

Mertens DM.

Eval Program Plann. 2016 Dec;59:102-108. doi: 10.1016/j.evalprogplan.2016.05.010. Epub 2016 Jun 3.

PMID:
27340047
22.

Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling.

Filarsky K, Garding A, Becker N, Wolf C, Zucknick M, Claus R, Weichenhan D, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D.

Haematologica. 2016 Jun;101(6):e249-53. doi: 10.3324/haematol.2015.138172. Epub 2016 Apr 14. No abstract available.

23.

Determination of groundwater mercury (II) content using a disposable gold modified screen printed carbon electrode.

Somé IT, Sakira AK, Mertens D, Ronkart SN, Kauffmann JM.

Talanta. 2016 May 15;152:335-40. doi: 10.1016/j.talanta.2016.02.033. Epub 2016 Feb 14.

PMID:
26992529
24.

Genomic Features: Impact on Pathogenesis and Treatment of Chronic Lymphocytic Leukemia.

Tausch E, Mertens D, Stilgenbauer S.

Oncol Res Treat. 2016;39(1-2):34-40. doi: 10.1159/000443906. Epub 2016 Jan 26. Review.

PMID:
26890126
25.

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia.

Oakes CC, Seifert M, Assenov Y, Gu L, Przekopowitz M, Ruppert AS, Wang Q, Imbusch CD, Serva A, Koser SD, Brocks D, Lipka DB, Bogatyrova O, Weichenhan D, Brors B, Rassenti L, Kipps TJ, Mertens D, Zapatka M, Lichter P, Döhner H, Küppers R, Zenz T, Stilgenbauer S, Byrd JC, Plass C.

Nat Genet. 2016 Mar;48(3):253-64. doi: 10.1038/ng.3488. Epub 2016 Jan 18.

26.

Experimental study of synchronization of coupled electrical self-oscillators and comparison to the Sakaguchi-Kuramoto model.

English LQ, Zeng Z, Mertens D.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Nov;92(5):052912. doi: 10.1103/PhysRevE.92.052912. Epub 2015 Nov 30.

PMID:
26651767
27.

Mutations driving CLL and their evolution in progression and relapse.

Landau DA, Tausch E, Taylor-Weiner AN, Stewart C, Reiter JG, Bahlo J, Kluth S, Bozic I, Lawrence M, Böttcher S, Carter SL, Cibulskis K, Mertens D, Sougnez CL, Rosenberg M, Hess JM, Edelmann J, Kless S, Kneba M, Ritgen M, Fink A, Fischer K, Gabriel S, Lander ES, Nowak MA, Döhner H, Hallek M, Neuberg D, Getz G, Stilgenbauer S, Wu CJ.

Nature. 2015 Oct 22;526(7574):525-30. doi: 10.1038/nature15395. Epub 2015 Oct 14.

28.

An experimental design approach to optimize an amperometric immunoassay on a screen printed electrode for Clostridium tetani antibody determination.

Patris S, Vandeput M, Kenfack GM, Mertens D, Dejaegher B, Kauffmann JM.

Biosens Bioelectron. 2016 Mar 15;77:457-63. doi: 10.1016/j.bios.2015.09.064. Epub 2015 Sep 30.

PMID:
26454827
29.

Exercise training improves peak oxygen consumption and haemodynamics in patients with severe pulmonary arterial hypertension and inoperable chronic thrombo-embolic pulmonary hypertension: a prospective, randomized, controlled trial.

Ehlken N, Lichtblau M, Klose H, Weidenhammer J, Fischer C, Nechwatal R, Uiker S, Halank M, Olsson K, Seeger W, Gall H, Rosenkranz S, Wilkens H, Mertens D, Seyfarth HJ, Opitz C, Ulrich S, Egenlauf B, Grünig E.

Eur Heart J. 2016 Jan 1;37(1):35-44. doi: 10.1093/eurheartj/ehv337. Epub 2015 Jul 31.

30.

Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia.

Opel D, Schnaiter A, Dodier D, Jovanovic M, Gerhardinger A, Idler I, Mertens D, Bullinger L, Stilgenbauer S, Fulda S.

Int J Cancer. 2015 Dec 15;137(12):2959-70. doi: 10.1002/ijc.29650. Epub 2015 Jul 31.

31.

Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia.

Baer C, Oakes CC, Ruppert AS, Claus R, Kim-Wanner SZ, Mertens D, Zenz T, Stilgenbauer S, Byrd JC, Plass C.

Int J Cancer. 2015 Sep 15;137(6):1352-61. doi: 10.1002/ijc.29491. Epub 2015 Mar 13.

32.

[Quality of life in pulmonal arterial hypertension and in chronic thromboembolic pulmonary hypertension].

Halank M, Speich R, Petkova D, Saxer S, Müller-Mottet S, Hasler E, Kolditz M, Wilkens H, Ehlken N, Lichtblau M, Egenlauf B, Kähler C, Lüneburg N, Mertens D, Schulz U, Barner A, Grünig E, Puhan M, Ulrich S.

Dtsch Med Wochenschr. 2014 Dec;139 Suppl 4:S126-35. doi: 10.1055/s-0034-1387482. Epub 2014 Dec 9. Review. German. No abstract available.

PMID:
25489682
33.

Flow-through enzyme immobilized amperometric detector for the rapid screening of acetylcholinesterase inhibitors by flow injection analysis.

Vandeput M, Parsajoo C, Vanheuverzwijn J, Patris S, Yardim Y, le Jeune A, Sarakbi A, Mertens D, Kauffmann JM.

J Pharm Biomed Anal. 2015 Jan;102:267-75. doi: 10.1016/j.jpba.2014.09.012. Epub 2014 Sep 30.

PMID:
25459923
34.

Stage of lactation and corresponding diets affect in situ protein degradation by dairy cows.

Schadt I, Mertens DR, Van Soest PJ, Azzaro G, Licitra G.

J Dairy Sci. 2014 Dec;97(12):7995-8007. doi: 10.3168/jds.2014-7987. Epub 2014 Oct 3.

35.

Advances in treating chronic lymphocytic leukemia.

Tausch E, Mertens D, Stilgenbauer S.

F1000Prime Rep. 2014 Aug 1;6:65. doi: 10.12703/P6-65. eCollection 2014. Review.

36.

Loss of cooperativity of secreted CD40L and increased dose-response to IL4 on CLL cell viability correlates with enhanced activation of NF-kB and STAT6.

Bhattacharya N, Reichenzeller M, Caudron-Herger M, Haebe S, Brady N, Diener S, Nothing M, Döhner H, Stilgenbauer S, Rippe K, Mertens D.

Int J Cancer. 2015 Jan 1;136(1):65-73. doi: 10.1002/ijc.28974. Epub 2014 May 27.

37.

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.

Stilgenbauer S, Schnaiter A, Paschka P, Zenz T, Rossi M, Döhner K, Bühler A, Böttcher S, Ritgen M, Kneba M, Winkler D, Tausch E, Hoth P, Edelmann J, Mertens D, Bullinger L, Bergmann M, Kless S, Mack S, Jäger U, Patten N, Wu L, Wenger MK, Fingerle-Rowson G, Lichter P, Cazzola M, Wendtner CM, Fink AM, Fischer K, Busch R, Hallek M, Döhner H.

Blood. 2014 May 22;123(21):3247-54. doi: 10.1182/blood-2014-01-546150. Epub 2014 Mar 20.

38.
39.

Thalidomide regulation of NF-κB proteins limits Tregs activity in chronic lymphocytic leukemia.

Skórka K, Bhattacharya N, Własiuk P, Kowal M, Mertens D, Dmoszyńska A, Giannopoulos K.

Adv Clin Exp Med. 2014 Jan-Feb;23(1):25-32.

40.

Prognostic and predictive factors in patients with chronic lymphocytic leukemia: relevant in the era of novel treatment approaches?

Mertens D, Stilgenbauer S.

J Clin Oncol. 2014 Mar 20;32(9):869-72. doi: 10.1200/JCO.2013.53.8421. Epub 2014 Feb 10. No abstract available.

PMID:
24516034
41.

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.

Oakes CC, Claus R, Gu L, Assenov Y, Hüllein J, Zucknick M, Bieg M, Brocks D, Bogatyrova O, Schmidt CR, Rassenti L, Kipps TJ, Mertens D, Lichter P, Döhner H, Stilgenbauer S, Byrd JC, Zenz T, Plass C.

Cancer Discov. 2014 Mar;4(3):348-61. doi: 10.1158/2159-8290.CD-13-0349. Epub 2013 Dec 19.

42.

In vivo processing assay based on a dual-luciferase reporter system to evaluate DROSHA enzymatic activity.

Bilan V, Allegra D, Kuchenbauer F, Mertens D.

Methods Mol Biol. 2014;1095:87-93. doi: 10.1007/978-1-62703-703-7_6.

PMID:
24166304
43.

Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia.

Allegra D, Bilan V, Garding A, Döhner H, Stilgenbauer S, Kuchenbauer F, Mertens D, Zucknick M.

Leukemia. 2014 Jan;28(1):98-107. doi: 10.1038/leu.2013.246. Epub 2013 Aug 26. Erratum in: Leukemia. 2014 Dec;28(12):2427. Zucknick, Manuela [Added].

PMID:
23974981
44.

NOTCH1, SF3B1, and TP53 mutations in fludarabine-refractory CLL patients treated with alemtuzumab: results from the CLL2H trial of the GCLLSG.

Schnaiter A, Paschka P, Rossi M, Zenz T, Bühler A, Winkler D, Cazzola M, Döhner K, Edelmann J, Mertens D, Kless S, Mack S, Busch R, Hallek M, Döhner H, Stilgenbauer S.

Blood. 2013 Aug 15;122(7):1266-70. doi: 10.1182/blood-2013-03-488197. Epub 2013 Jul 2.

45.

Determination of aminothiols by liquid chromatography with amperometric detection at a silver electrode: application to white wines.

Sarakbi A, Aydogmus Z, Dago A, Mertens D, Dewert JY, Kauffmann JM.

Anal Chim Acta. 2013 Jul 5;786:22-8. doi: 10.1016/j.aca.2013.04.070. Epub 2013 May 22.

PMID:
23790287
46.

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M, Caudron-Herger M, Oakes C, Fleig V, Keklikoglou I, Allegra D, Serra L, Thakurela S, Tiwari V, Weichenhan D, Benner A, Radlwimmer B, Zentgraf H, Wiemann S, Rippe K, Plass C, Döhner H, Lichter P, Stilgenbauer S, Mertens D.

PLoS Genet. 2013 Apr;9(4):e1003373. doi: 10.1371/journal.pgen.1003373. Epub 2013 Apr 4.

47.

Circulating microRNAs in hematological diseases: principles, challenges, and perspectives.

Grasedieck S, Sorrentino A, Langer C, Buske C, Döhner H, Mertens D, Kuchenbauer F.

Blood. 2013 Jun 20;121(25):4977-84. doi: 10.1182/blood-2013-01-480079. Epub 2013 Apr 2. Review.

48.

Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia.

Wei QX, Claus R, Hielscher T, Mertens D, Raval A, Oakes CC, Tanner SM, de la Chapelle A, Byrd JC, Stilgenbauer S, Plass C.

PLoS One. 2013;8(1):e55261. doi: 10.1371/journal.pone.0055261. Epub 2013 Jan 28.

49.

Missing the notch in NOTCH1.

Kugler SJ, Schnaiter A, Stilgenbauer S, Mertens D.

Leuk Lymphoma. 2013 Aug;54(8):1579-80. doi: 10.3109/10428194.2013.767459. Epub 2013 Feb 16. No abstract available.

PMID:
23323947
50.

Telomere length in mantle cell lymphoma.

Jebaraj BM, Kienle D, Lechel A, Mertens D, Heuberger M, Ott G, Rosenwald A, Barth TF, Möller P, Zenz T, Döhner H, Stilgenbauer S.

Blood. 2013 Feb 14;121(7):1184-7. doi: 10.1182/blood-2012-08-452649. Epub 2012 Dec 14.

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