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Items: 10


CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.

Post JB, Hami N, Mertens AEE, Elfrink S, Bos JL, Snippert HJG.

Oncotarget. 2019 Feb 15;10(14):1440-1457. doi: 10.18632/oncotarget.26677. eCollection 2019 Feb 15.


Angiogenic T-cells and putative endothelial progenitor cells in hypertension-related cerebral small vessel disease.

Rouhl RP, Mertens AE, van Oostenbrugge RJ, Damoiseaux JG, Debrus-Palmans LL, Henskens LH, Kroon AA, de Leeuw PW, Lodder J, Tervaert JW.

Stroke. 2012 Jan;43(1):256-8. doi: 10.1161/STROKEAHA.111.632208. Epub 2011 Oct 6.


The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.

Rygiel TP, Mertens AE, Strumane K, van der Kammen R, Collard JG.

J Cell Sci. 2008 Apr 15;121(Pt 8):1183-92. doi: 10.1242/jcs.017194. Epub 2008 Mar 18.


The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity.

Pegtel DM, Ellenbroek SI, Mertens AE, van der Kammen RA, de Rooij J, Collard JG.

Curr Biol. 2007 Oct 9;17(19):1623-34. Epub 2007 Sep 6.


The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization.

GĂ©rard A, Mertens AE, van der Kammen RA, Collard JG.

J Cell Biol. 2007 Mar 12;176(6):863-75.


Tiam1 takes PARt in cell polarity.

Mertens AE, Pegtel DM, Collard JG.

Trends Cell Biol. 2006 Jun;16(6):308-16. Epub 2006 May 2. Review.


The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.

Hamelers IH, Olivo C, Mertens AE, Pegtel DM, van der Kammen RA, Sonnenberg A, Collard JG.

J Cell Biol. 2005 Dec 5;171(5):871-81.


The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex.

Mertens AE, Rygiel TP, Olivo C, van der Kammen R, Collard JG.

J Cell Biol. 2005 Sep 26;170(7):1029-37.


Regulation of Tiam1-Rac signalling.

Mertens AE, Roovers RC, Collard JG.

FEBS Lett. 2003 Jul 3;546(1):11-6. Review.


Expression of Ep-CAM shifts the state of cadherin-mediated adhesions from strong to weak.

Winter MJ, Nagelkerken B, Mertens AE, Rees-Bakker HA, Briaire-de Bruijn IH, Litvinov SV.

Exp Cell Res. 2003 Apr 15;285(1):50-8.


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