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Items: 25

1.

A two-step risk assessment method for radiofrequency ablations of spine metastases.

Merten N, Adler S, Hille G, Hanses M, Becker M, Saalfeld S, Preim B.

Comput Biol Med. 2019 May;108:174-181. doi: 10.1016/j.compbiomed.2019.03.007. Epub 2019 Mar 16.

PMID:
31005009
2.

Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation.

Merten N, Fischer J, Simon K, Zhang L, Schröder R, Peters L, Letombe AG, Hennen S, Schrage R, Bödefeld T, Vermeiren C, Gillard M, Mohr K, Lu QR, Brüstle O, Gomeza J, Kostenis E.

Cell Chem Biol. 2018 Jun 21;25(6):775-786.e5. doi: 10.1016/j.chembiol.2018.03.012. Epub 2018 Apr 26.

PMID:
29706593
3.

Lack of beta-arrestin signaling in the absence of active G proteins.

Grundmann M, Merten N, Malfacini D, Inoue A, Preis P, Simon K, Rüttiger N, Ziegler N, Benkel T, Schmitt NK, Ishida S, Müller I, Reher R, Kawakami K, Inoue A, Rick U, Kühl T, Imhof D, Aoki J, König GM, Hoffmann C, Gomeza J, Wess J, Kostenis E.

Nat Commun. 2018 Jan 23;9(1):341. doi: 10.1038/s41467-017-02661-3.

4.

The Orphan Receptor GPR17 Is Unresponsive to Uracil Nucleotides and Cysteinyl Leukotrienes.

Simon K, Merten N, Schröder R, Hennen S, Preis P, Schmitt NK, Peters L, Schrage R, Vermeiren C, Gillard M, Mohr K, Gomeza J, Kostenis E.

Mol Pharmacol. 2017 May;91(5):518-532. doi: 10.1124/mol.116.107904. Epub 2017 Mar 2. Erratum in: Mol Pharmacol. 2017 Jul;92 (1):100.

PMID:
28254957
5.

Biosynthetic Studies on Acetosellin and Structure Elucidation of a New Acetosellin Derivative.

Hufendiek P, Stölben SSM, Kehraus S, Merten N, Harms H, Crüsemann M, Arslan I, Gütschow M, Schneider T, König GM.

Planta Med. 2017 Aug;83(12-13):1044-1052. doi: 10.1055/s-0042-124493. Epub 2017 Jan 12.

PMID:
28081580
6.

The experimental power of FR900359 to study Gq-regulated biological processes.

Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E.

Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156.

7.

The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules.

Simon K, Hennen S, Merten N, Blättermann S, Gillard M, Kostenis E, Gomeza J.

J Biol Chem. 2016 Jan 8;291(2):705-18. doi: 10.1074/jbc.M115.683953. Epub 2015 Nov 30.

8.

Meta-analysis of the association of the SLC6A3 3'-UTR VNTR with cognition.

Ettinger U, Merten N, Kambeitz J.

Neurosci Biobehav Rev. 2016 Jan;60:72-81. doi: 10.1016/j.neubiorev.2015.09.021. Epub 2015 Nov 22. Review.

PMID:
26593110
9.

[Causes, diagnostics and course of disease in 194 cats with anemia].

Merten N, Weingart C, Kohn B.

Berl Munch Tierarztl Wochenschr. 2015 Sep-Oct;128(9-10):384-93. German.

PMID:
26591384
10.

Association of COMT and SLC6A3 polymorphisms with impulsivity, response inhibition and brain function.

Kasparbauer AM, Merten N, Aichert DS, Wöstmann N, Meindl T, Rujescu D, Ettinger U.

Cortex. 2015 Oct;71:219-31. doi: 10.1016/j.cortex.2015.07.002. Epub 2015 Jul 15.

PMID:
26245713
11.

Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist.

Hennen S, Wang H, Peters L, Merten N, Simon K, Spinrath A, Blättermann S, Akkari R, Schrage R, Schröder R, Schulz D, Vermeiren C, Zimmermann K, Kehraus S, Drewke C, Pfeifer A, König GM, Mohr K, Gillard M, Müller CE, Lu QR, Gomeza J, Kostenis E.

Sci Signal. 2013 Oct 22;6(298):ra93. doi: 10.1126/scisignal.2004350.

12.

A Single Nucleotide Polymorphism within the Interferon Gamma Receptor 2 Gene Perfectly Coincides with Polledness in Holstein Cattle.

Glatzer S, Merten NJ, Dierks C, Wöhlke A, Philipp U, Distl O.

PLoS One. 2013 Jun 21;8(6):e67992. doi: 10.1371/journal.pone.0067992. Print 2013.

13.

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling.

Bock A, Merten N, Schrage R, Dallanoce C, Bätz J, Klöckner J, Schmitz J, Matera C, Simon K, Kebig A, Peters L, Müller A, Schrobang-Ley J, Tränkle C, Hoffmann C, De Amici M, Holzgrabe U, Kostenis E, Mohr K.

Nat Commun. 2012;3:1044. doi: 10.1038/ncomms2028.

14.

Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.

Schröder R, Schmidt J, Blättermann S, Peters L, Janssen N, Grundmann M, Seemann W, Kaufel D, Merten N, Drewke C, Gomeza J, Milligan G, Mohr K, Kostenis E.

Nat Protoc. 2011 Oct 20;6(11):1748-60. doi: 10.1038/nprot.2011.386.

PMID:
22015845
15.

Conjugated linoleic acids mediate insulin release through islet G protein-coupled receptor FFA1/GPR40.

Schmidt J, Liebscher K, Merten N, Grundmann M, Mielenz M, Sauerwein H, Christiansen E, Due-Hansen ME, Ulven T, Ullrich S, Gomeza J, Drewke C, Kostenis E.

J Biol Chem. 2011 Apr 8;286(14):11890-4. doi: 10.1074/jbc.C110.200477. Epub 2011 Feb 21.

16.

Structure-Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469.

Christiansen E, Due-Hansen ME, Urban C, Merten N, Pfleiderer M, Karlsen KK, Rasmussen SS, Steensgaard M, Hamacher A, Schmidt J, Drewke C, Petersen RK, Kristiansen K, Ullrich S, Kostenis E, Kassack MU, Ulven T.

ACS Med Chem Lett. 2010 Jul 2;1(7):345-9. doi: 10.1021/ml100106c. eCollection 2010 Oct 14.

17.

Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements.

Schröder R, Janssen N, Schmidt J, Kebig A, Merten N, Hennen S, Müller A, Blättermann S, Mohr-Andrä M, Zahn S, Wenzel J, Smith NJ, Gomeza J, Drewke C, Milligan G, Mohr K, Kostenis E.

Nat Biotechnol. 2010 Sep;28(9):943-9. doi: 10.1038/nbt.1671. Epub 2010 Aug 15.

PMID:
20711173
18.

Lack of evidence for AT1R/B2R heterodimerization in COS-7, HEK293, and NIH3T3 cells: how common is the AT1R/B2R heterodimer?

Hansen JL, Hansen JT, Speerschneider T, Lyngsø C, Erikstrup N, Burstein ES, Weiner DM, Walther T, Makita N, Iiri T, Merten N, Kostenis E, Sheikh SP.

J Biol Chem. 2009 Jan 16;284(3):1831-9. doi: 10.1074/jbc.M804607200. Epub 2008 Nov 18.

19.

The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.

Schröder R, Merten N, Mathiesen JM, Martini L, Kruljac-Letunic A, Krop F, Blaukat A, Fang Y, Tran E, Ulven T, Drewke C, Whistler J, Pardo L, Gomeza J, Kostenis E.

J Biol Chem. 2009 Jan 9;284(2):1324-36. doi: 10.1074/jbc.M806867200. Epub 2008 Nov 14.

20.

Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes.

Christiansen E, Urban C, Merten N, Liebscher K, Karlsen KK, Hamacher A, Spinrath A, Bond AD, Drewke C, Ullrich S, Kassack MU, Kostenis E, Ulven T.

J Med Chem. 2008 Nov 27;51(22):7061-4. doi: 10.1021/jm8010178.

PMID:
18947221
21.

The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor.

Chee MJ, Mörl K, Lindner D, Merten N, Zamponi GW, Light PE, Beck-Sickinger AG, Colmers WF.

J Biol Chem. 2008 Nov 28;283(48):33337-46. doi: 10.1074/jbc.M804671200. Epub 2008 Sep 23. Erratum in: J Biol Chem. 2009 Feb 6;284(6):4040.

22.

GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system.

Lindner D, van Dieck J, Merten N, Mörl K, Günther R, Hofmann HJ, Beck-Sickinger AG.

Biochemistry. 2008 Jun 3;47(22):5905-14. doi: 10.1021/bi800181k. Epub 2008 May 6.

PMID:
18457425
23.

Synthesis and in vitro evaluation of a selective antagonist and the corresponding radioligand for the prostaglandin D2 receptor CRTH2.

Ulven T, Gallen MJ, Nielsen MC, Merten N, Schmidt C, Mohr K, Tränkle C, Kostenis E.

Bioorg Med Chem Lett. 2007 Nov 1;17(21):5924-7. Epub 2007 Aug 22.

PMID:
17845848
24.

Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.

Merten N, Lindner D, Rabe N, Römpler H, Mörl K, Schöneberg T, Beck-Sickinger AG.

J Biol Chem. 2007 Mar 9;282(10):7543-51. Epub 2007 Jan 4.

25.

Molecular ligand-receptor interaction of the NPY/PP peptide family.

Merten N, Beck-Sickinger AG.

EXS. 2006;(95):35-62. Review. No abstract available.

PMID:
16382996

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