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Items: 15

Select item 268196711.

Optimizing Ligand Efficiency of Selective Androgen Receptor Modulators (SARMs).

Handlon AL, Schaller LT, Leesnitzer LM, Merrihew RV, Poole C, Ulrich JC, Wilson JW, Cadilla R, Turnbull P.

ACS Med Chem Lett. 2015 Nov 19;7(1):83-8. doi: 10.1021/acsmedchemlett.5b00377. eCollection 2016 Jan 14.

PMID:: 26819671

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Select item 217987392.

Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist.

Sime M, Allan AC, Chapman P, Fieldhouse C, Giblin GM, Healy MP, Lambert MH, Leesnitzer LM, Lewis A, Merrihew RV, Rutter RA, Sasse R, Shearer BG, Willson TM, Xu RX, Virley DJ.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5568-72. doi: 10.1016/j.bmcl.2011.06.088. Epub 2011 Jun 29. Erratum in: Bioorg Med Chem Lett. 2013 Feb 15;23(4):1143. Wilson, Timothy M [corrected to Willson, Timothy M].

PMID:: 21798739

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Select item 214147823.

Phenoxyacetic acids as PPARδ partial agonists: synthesis, optimization, and in vivo efficacy.

Evans KA, Shearer BG, Wisnoski DD, Shi D, Sparks SM, Sternbach DD, Winegar DA, Billin AN, Britt C, Way JM, Epperly AH, Leesnitzer LM, Merrihew RV, Xu RX, Lambert MH, Jin J.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2345-50. doi: 10.1016/j.bmcl.2011.02.077. Epub 2011 Mar 15.

PMID:: 21414782

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Select item 201285944.

Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist.

Shearer BG, Wiethe RW, Ashe A, Billin AN, Way JM, Stanley TB, Wagner CD, Xu RX, Leesnitzer LM, Merrihew RV, Shearer TW, Jeune MR, Ulrich JC, Willson TM.

J Med Chem. 2010 Feb 25;53(4):1857-61. doi: 10.1021/jm900464j.

PMID:: 20128594

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Select item 187227725.

Discovery of a novel class of PPARdelta partial agonists.

Shearer BG, Patel HS, Billin AN, Way JM, Winegar DA, Lambert MH, Xu RX, Leesnitzer LM, Merrihew RV, Huet S, Willson TM.

Bioorg Med Chem Lett. 2008 Sep 15;18(18):5018-22. doi: 10.1016/j.bmcl.2008.08.011. Epub 2008 Aug 9.

PMID:: 18722772

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Select item 169970146.

Baculoviruses and mammalian cell-based assays for drug screening.

Condreay JP, Ames RS, Hassan NJ, Kost TA, Merrihew RV, Mossakowska DE, Pountney DJ, Romanos MA.

Adv Virus Res. 2006;68:255-86. Review. No abstract available.

PMID:: 16997014

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Select item 166755137.

Cloning, tissue expression, and regulation of beagle dog CYP4A genes.

Graham RA, Goodwin B, Merrihew RV, Krol WL, Lecluyse EL.

Toxicol Sci. 2006 Aug;92(2):356-67. Epub 2006 May 4.

PMID:: 16675513

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Select item 162167758.

The application of BacMam technology in nuclear receptor drug discovery.

Boudjelal M, Mason SJ, Katso RM, Fleming JM, Parham JH, Condreay JP, Merrihew RV, Cairns WJ.

Biotechnol Annu Rev. 2005;11:101-25. Review.

PMID:: 16216775

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Select item 161297779.

Evaluation of cell-based assays for steroid nuclear receptors delivered by recombinant baculoviruses.

Katso RM, Parham JH, Caivano M, Clay WC, Condreay JP, Gray DW, Lindley KM, Mason SJ, Rieger J, Wakes NC, Cairns WJ, Merrihew RV.

J Biomol Screen. 2005 Oct;10(7):715-24. Epub 2005 Aug 29.

PMID:: 16129777

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Select item 1497060410.

Baculovirus-mediated gene delivery into mammalian cells.

Merrihew RV, Kost TA, Condreay JP.

Methods Mol Biol. 2004;246:355-65.

PMID:: 14970604

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Select item 1113430311.

Chromosomal integration of transduced recombinant baculovirus DNA in mammalian cells.

Merrihew RV, Clay WC, Condreay JP, Witherspoon SM, Dallas WS, Kost TA.

J Virol. 2001 Jan;75(2):903-9.

PMID:: 11134303

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Select item 1094259112.

Altered response of a human squamous cell carcinoma cell line to 1, 25-dihydroxyvitamin D(3) after transfer of a normal chromosome 11.

Merrihew RV, Cruickshank RD, Conway K, Weissman BE.

Exp Cell Res. 2000 Aug 25;259(1):191-203.

PMID:: 10942591

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Select item 860431913.

The influence of a (GT)29 microsatellite sequence on homologous recombination in the hamster adenine phosphoribosyltransferase gene.

Sargent RG, Merrihew RV, Nairn R, Adair G, Meuth M, Wilson JH.

Nucleic Acids Res. 1996 Feb 15;24(4):746-53.

PMID:: 8604319

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Select item 852428514.

High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome.

Merrihew RV, Marburger K, Pennington SL, Roth DB, Wilson JH.

Mol Cell Biol. 1996 Jan;16(1):10-8.

PMID:: 8524285

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Select item 861912715.

Efficient modification of the APRT gene by FLP/FRT site-specific targeting.

Merrihew RV, Sargent RG, Wilson JH.

Somat Cell Mol Genet. 1995 Sep;21(5):299-307.

PMID:: 8619127

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