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Items: 1 to 50 of 310

1.

Magnetic resonance measurements of cellular and sub-cellular membrane structures in live and fixed neural tissue.

Williamson NH, Ravin R, Benjamini D, Merkle H, Falgairolle M, O'Donovan MJ, Blivis D, Ide D, Cai TX, Ghorashi NS, Bai R, Basser PJ.

Elife. 2019 Dec 12;8. pii: e51101. doi: 10.7554/eLife.51101.

2.

Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice.

Kishimoto S, Brender JR, Crooks DR, Matsumoto S, Seki T, Oshima N, Merkle H, Lin P, Reed G, Chen AP, Ardenkjaer-Larsen JH, Munasinghe J, Saito K, Yamamoto K, Choyke PL, Mitchell J, Lane AN, Fan TW, Linehan WM, Krishna MC.

Elife. 2019 Aug 13;8. pii: e46312. doi: 10.7554/eLife.46312.

3.

Discontinuing antiepileptic drugs in long-standing idiopathic generalised epilepsy.

Vorderwülbecke BJ, Kirschbaum A, Merkle H, Senf P, Holtkamp M.

J Neurol. 2019 Oct;266(10):2554-2559. doi: 10.1007/s00415-019-09457-z. Epub 2019 Jul 2.

PMID:
31267208
4.

An Albumin-Binding T1- T2 Dual-Modal MRI Contrast Agents for Improved Sensitivity and Accuracy in Tumor Imaging.

Zhou Z, Bai R, Wang Z, Bryant H, Lang L, Merkle H, Munasinghe J, Tang L, Tang W, Tian R, Yu G, Ma Y, Niu G, Gao J, Chen X.

Bioconjug Chem. 2019 Jun 19;30(6):1821-1829. doi: 10.1021/acs.bioconjchem.9b00349. Epub 2019 May 31.

PMID:
31117347
5.

Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization.

Brender JR, Kishimoto S, Merkle H, Reed G, Hurd RE, Chen AP, Ardenkjaer-Larsen JH, Munasinghe J, Saito K, Seki T, Oshima N, Yamamoto K, Choyke PL, Mitchell J, Krishna MC.

Sci Rep. 2019 Mar 4;9(1):3410. doi: 10.1038/s41598-019-38981-1.

6.

Investigation of the BOLD and CBV fMRI responses to somatosensory stimulation in awake marmosets (Callithrix jacchus).

Hirano Y, Yen CC, Liu JV, Mackel JB, Merkle H, Nascimento GC, Stefanovic B, Silva AC.

NMR Biomed. 2018 Mar;31(3). doi: 10.1002/nbm.3864. Epub 2017 Dec 29.

7.

In vivo kinetics and nonradioactive imaging of rapidly proliferating cells in graft-versus-host disease.

Buxbaum NP, Farthing DE, Maglakelidze N, Lizak M, Merkle H, Carpenter AC, Oliver BU, Kapoor V, Castro E, Swan GA, Dos Santos LM, Bouladoux NJ, Bare CV, Flomerfelt FA, Eckhaus MA, Telford WG, Belkaid Y, Bosselut RJ, Gress RE.

JCI Insight. 2017 Jun 15;2(12). pii: 92851. doi: 10.1172/jci.insight.92851. eCollection 2017 Jun 15.

8.

Long-term outcome in adolescent-onset generalized genetic epilepsies.

Vorderwülbecke BJ, Kowski AB, Kirschbaum A, Merkle H, Senf P, Janz D, Holtkamp M.

Epilepsia. 2017 Jul;58(7):1244-1250. doi: 10.1111/epi.13761. Epub 2017 May 2.

9.

Surface-assembled poly(I:C) on PEGylated PLGA microspheres as vaccine adjuvant: APC activation and bystander cell stimulation.

Hafner AM, Corthésy B, Textor M, Merkle HP.

Int J Pharm. 2016 Nov 30;514(1):176-188. doi: 10.1016/j.ijpharm.2016.07.042.

PMID:
27863662
10.

Endosphenoidal coil for intraoperative magnetic resonance imaging of the pituitary gland during transsphenoidal surgery.

Chittiboina P, Talagala SL, Merkle H, Sarlls JE, Montgomery BK, Piazza MG, Scott G, Ray-Chaudhury A, Lonser RR, Oldfield EH, Koretsky AP, Butman JA.

J Neurosurg. 2016 Dec;125(6):1451-1459. Epub 2016 Mar 18.

11.

Sensory and optogenetically driven single-vessel fMRI.

Yu X, He Y, Wang M, Merkle H, Dodd SJ, Silva AC, Koretsky AP.

Nat Methods. 2016 Apr;13(4):337-40. doi: 10.1038/nmeth.3765. Epub 2016 Feb 8.

12.

Drug delivery's quest for polymers: Where are the frontiers?

Merkle HP.

Eur J Pharm Biopharm. 2015 Nov;97(Pt B):293-303. doi: 10.1016/j.ejpb.2015.04.038. Review.

PMID:
26614554
13.

Simultaneous calcium fluorescence imaging and MR of ex vivo organotypic cortical cultures: a new test bed for functional MRI.

Bai R, Klaus A, Bellay T, Stewart C, Pajevic S, Nevo U, Merkle H, Plenz D, Basser PJ.

NMR Biomed. 2015 Dec;28(12):1726-38. doi: 10.1002/nbm.3424. Epub 2015 Oct 29.

PMID:
26510537
14.

Optically controlled switch-mode current-source amplifiers for on-coil implementation in high-field parallel transmission.

Gudino N, Duan Q, de Zwart JA, Murphy-Boesch J, Dodd SJ, Merkle H, van Gelderen P, Duyn JH.

Magn Reson Med. 2016 Jul;76(1):340-9. doi: 10.1002/mrm.25857. Epub 2015 Aug 10.

15.

A 7T spine array based on electric dipole transmitters.

Duan Q, Nair G, Gudino N, de Zwart JA, van Gelderen P, Murphy-Boesch J, Reich DS, Duyn JH, Merkle H.

Magn Reson Med. 2015 Oct;74(4):1189-97. doi: 10.1002/mrm.25817. Epub 2015 Jul 20.

16.

7 Tesla magnetic resonance imaging to detect cortical pathology in multiple sclerosis.

Yao B, Hametner S, van Gelderen P, Merkle H, Chen C, Lassmann H, Duyn JH, Bagnato F.

PLoS One. 2014 Oct 10;9(10):e108863. doi: 10.1371/journal.pone.0108863. eCollection 2014.

17.

In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization.

Matsumoto S, Saito K, Takakusagi Y, Matsuo M, Munasinghe JP, Morris HD, Lizak MJ, Merkle H, Yasukawa K, Devasahayam N, Suburamanian S, Mitchell JB, Krishna MC.

Antioxid Redox Signal. 2014 Sep 10;21(8):1145-55. doi: 10.1089/ars.2013.5725. Epub 2014 Apr 7.

18.

Diffusion properties of conventional and calcium-sensitive MRI contrast agents in the rat cerebral cortex.

Hagberg GE, Mamedov I, Power A, Beyerlein M, Merkle H, Kiselev VG, Dhingra K, Kubìček V, Angelovski G, Logothetis NK.

Contrast Media Mol Imaging. 2014 Jan-Feb;9(1):71-82. doi: 10.1002/cmmi.1535.

19.

Long-term outcome in epilepsy with grand mal on awakening: forty years of follow-up.

Holtkamp M, Kowski AB, Merkle H, Janz D.

Ann Neurol. 2014 Feb;75(2):298-302. doi: 10.1002/ana.24103. Epub 2014 Feb 20.

PMID:
24395517
20.

Remodeling of tissue-engineered bone structures in vivo.

Hofmann S, Hilbe M, Fajardo RJ, Hagenmüller H, Nuss K, Arras M, Müller R, von Rechenberg B, Kaplan DL, Merkle HP, Meinel L.

Eur J Pharm Biopharm. 2013 Sep;85(1):119-29. doi: 10.1016/j.ejpb.2013.02.011.

21.

Biocompatibility and osteoconduction of macroporous silk fibroin implants in cortical defects in sheep.

Uebersax L, Apfel T, Nuss KM, Vogt R, Kim HY, Meinel L, Kaplan DL, Auer JA, Merkle HP, von Rechenberg B.

Eur J Pharm Biopharm. 2013 Sep;85(1):107-18. doi: 10.1016/j.ejpb.2013.05.008.

PMID:
23958322
22.

Impact of IGF-I release kinetics on bone healing: a preliminary study in sheep.

Luginbuehl V, Zoidis E, Meinel L, von Rechenberg B, Gander B, Merkle HP.

Eur J Pharm Biopharm. 2013 Sep;85(1):99-106. doi: 10.1016/j.ejpb.2013.03.004.

PMID:
23958321
23.

Perivenular brain lesions in a primate multiple sclerosis model at 7-tesla magnetic resonance imaging.

Gaitán MI, Maggi P, Wohler J, Leibovitch E, Sati P, Calandri IL, Merkle H, Massacesi L, Silva AC, Jacobson S, Reich DS.

Mult Scler. 2014 Jan;20(1):64-71. doi: 10.1177/1352458513492244. Epub 2013 Jun 17.

24.

Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant.

Hafner AM, Corthésy B, Merkle HP.

Adv Drug Deliv Rev. 2013 Oct;65(10):1386-99. doi: 10.1016/j.addr.2013.05.013. Epub 2013 Jun 7. Review.

PMID:
23751781
25.

An embedded four-channel receive-only RF coil array for fMRI experiments of the somatosensory pathway in conscious awake marmosets.

Papoti D, Yen CC, Mackel JB, Merkle H, Silva AC.

NMR Biomed. 2013 Nov;26(11):1395-402. doi: 10.1002/nbm.2965. Epub 2013 May 22.

26.

Micro-compartment specific T2* relaxation in the brain.

Sati P, van Gelderen P, Silva AC, Reich DS, Merkle H, de Zwart JA, Duyn JH.

Neuroimage. 2013 Aug 15;77:268-78. doi: 10.1016/j.neuroimage.2013.03.005. Epub 2013 Mar 22.

27.

High-resolution fMRI reveals laminar differences in neurovascular coupling between positive and negative BOLD responses.

Goense J, Merkle H, Logothetis NK.

Neuron. 2012 Nov 8;76(3):629-39. doi: 10.1016/j.neuron.2012.09.019.

28.

EPR oxygen imaging and hyperpolarized 13C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.

Matsumoto S, Saito K, Yasui H, Morris HD, Munasinghe JP, Lizak M, Merkle H, Ardenkjaer-Larsen JH, Choudhuri R, Devasahayam N, Subramanian S, Koretsky AP, Mitchell JB, Krishna MC.

Magn Reson Med. 2013 May;69(5):1443-50. doi: 10.1002/mrm.24355. Epub 2012 Jun 12.

29.

Surface assembly of poly(I:C) on PEGylated microspheres to shield from adverse interactions with fibroblasts.

Hafner AM, Burschowsky D, Corthésy B, Textor M, Merkle HP.

J Control Release. 2012 Apr 30;159(2):204-14. doi: 10.1016/j.jconrel.2012.02.002. Epub 2012 Feb 10.

PMID:
22349184
30.

Electrospun matrices for localized drug delivery: current technologies and selected biomedical applications.

Meinel AJ, Germershaus O, Luhmann T, Merkle HP, Meinel L.

Eur J Pharm Biopharm. 2012 May;81(1):1-13. doi: 10.1016/j.ejpb.2012.01.016. Epub 2012 Feb 11. Review.

PMID:
22342778
31.

Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla.

Bagnato F, Hametner S, Yao B, van Gelderen P, Merkle H, Cantor FK, Lassmann H, Duyn JH.

Brain. 2011 Dec;134(Pt 12):3602-15. doi: 10.1093/brain/awr278.

32.

Chronic multiple sclerosis lesions: characterization with high-field-strength MR imaging.

Yao B, Bagnato F, Matsuura E, Merkle H, van Gelderen P, Cantor FK, Duyn JH.

Radiology. 2012 Jan;262(1):206-15. doi: 10.1148/radiol.11110601. Epub 2011 Nov 14.

33.

T2*-based fiber orientation mapping.

Lee J, van Gelderen P, Kuo LW, Merkle H, Silva AC, Duyn JH.

Neuroimage. 2011 Jul 1;57(1):225-234. doi: 10.1016/j.neuroimage.2011.04.026. Epub 2011 Apr 22.

34.

Transmit B1-field correction at 7 T using actively tuned coupled inner elements.

Merkle H, Murphy-Boesch J, van Gelderen P, Wang S, Li TQ, Koretsky AP, Duyn JH.

Magn Reson Med. 2011 Sep;66(3):901-10. doi: 10.1002/mrm.22864. Epub 2011 Mar 24.

35.

Longitudinal functional magnetic resonance imaging in animal models.

Silva AC, Liu JV, Hirano Y, Leoni RF, Merkle H, Mackel JB, Zhang XF, Nascimento GC, Stefanovic B.

Methods Mol Biol. 2011;711:281-302. doi: 10.1007/978-1-61737-992-5_14. Review.

36.

Tuning the immune response of dendritic cells to surface-assembled poly(I:C) on microspheres through synergistic interactions between phagocytic and TLR3 signaling.

Hafner AM, Corthésy B, Textor M, Merkle HP.

Biomaterials. 2011 Apr;32(10):2651-61. doi: 10.1016/j.biomaterials.2010.12.021. Epub 2011 Jan 8.

PMID:
21216459
37.

Silk fibroin as a vehicle for drug delivery applications.

Wenk E, Merkle HP, Meinel L.

J Control Release. 2011 Mar 10;150(2):128-41. doi: 10.1016/j.jconrel.2010.11.007. Epub 2010 Nov 6. Review.

PMID:
21059377
38.

IkappaBbeta is an essential co-activator for LPS-induced IL-1beta transcription in vivo.

Scheibel M, Klein B, Merkle H, Schulz M, Fritsch R, Greten FR, Arkan MC, Schneider G, Schmid RM.

J Exp Med. 2010 Nov 22;207(12):2621-30. doi: 10.1084/jem.20100864. Epub 2010 Oct 25.

39.

The effects of electrical microstimulation on cortical signal propagation.

Logothetis NK, Augath M, Murayama Y, Rauch A, Sultan F, Goense J, Oeltermann A, Merkle H.

Nat Neurosci. 2010 Oct;13(10):1283-91. doi: 10.1038/nn.2631. Epub 2010 Sep 5.

PMID:
20818384
40.

Flexible, phase-matched, linear receive arrays for high-field MRI in monkeys.

Goense J, Logothetis NK, Merkle H.

Magn Reson Imaging. 2010 Oct;28(8):1183-91. doi: 10.1016/j.mri.2010.03.026. Epub 2010 Apr 24.

PMID:
20456890
41.

Sensitivity of MRI resonance frequency to the orientation of brain tissue microstructure.

Lee J, Shmueli K, Fukunaga M, van Gelderen P, Merkle H, Silva AC, Duyn JH.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5130-5. doi: 10.1073/pnas.0910222107. Epub 2010 Mar 2. Erratum in: Proc Natl Acad Sci U S A. 2010 May 4;107(18):8498.

42.

Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast.

Fukunaga M, Li TQ, van Gelderen P, de Zwart JA, Shmueli K, Yao B, Lee J, Maric D, Aronova MA, Zhang G, Leapman RD, Schenck JF, Merkle H, Duyn JH.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3834-9. doi: 10.1073/pnas.0911177107. Epub 2010 Feb 3.

43.

Design and validation of a novel bioreactor principle to combine online micro-computed tomography monitoring and mechanical loading in bone tissue engineering.

Hagenmüller H, Hitz M, Merkle HP, Meinel L, Müller R.

Rev Sci Instrum. 2010 Jan;81(1):014303. doi: 10.1063/1.3284787.

PMID:
20113118
44.

The use of sulfonated silk fibroin derivatives to control binding, delivery and potency of FGF-2 in tissue regeneration.

Wenk E, Murphy AR, Kaplan DL, Meinel L, Merkle HP, Uebersax L.

Biomaterials. 2010 Feb;31(6):1403-13. doi: 10.1016/j.biomaterials.2009.11.006. Epub 2009 Nov 25.

PMID:
19942287
45.

Characterization of T(2)* heterogeneity in human brain white matter.

Li TQ, Yao B, van Gelderen P, Merkle H, Dodd S, Talagala L, Koretsky AP, Duyn J.

Magn Reson Med. 2009 Dec;62(6):1652-7. doi: 10.1002/mrm.22156.

46.

Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response.

Fischer S, Schlosser E, Mueller M, Csaba N, Merkle HP, Groettrup M, Gander B.

J Drug Target. 2009 Sep;17(8):652-61. doi: 10.1080/10611860903119656.

PMID:
19622019
47.

Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering.

Garcia-Fuentes M, Meinel AJ, Hilbe M, Meinel L, Merkle HP.

Biomaterials. 2009 Oct;30(28):5068-76. doi: 10.1016/j.biomaterials.2009.06.008. Epub 2009 Jun 28.

PMID:
19564040
48.

Biopolymer-based growth factor delivery for tissue repair: from natural concepts to engineered systems.

Uebersax L, Merkle HP, Meinel L.

Tissue Eng Part B Rev. 2009 Sep;15(3):263-89. doi: 10.1089/ten.TEB.2008.0668. Review.

PMID:
19416020
49.

Multisequence-imaging protocols to detect cortical lesions of patients with multiple sclerosis: observations from a post-mortem 3 Tesla imaging study.

Bagnato F, Yao B, Cantor F, Merkle H, Condon E, Montequin M, Moore S, Quezado M, Tkaczyk D, McFarland H.

J Neurol Sci. 2009 Jul 15;282(1-2):80-5. doi: 10.1016/j.jns.2009.03.021. Epub 2009 Apr 23.

50.

B1 homogenization in MRI by multilayer coupled coils.

Wang S, Murphy-Boesch J, Merkle H, Koretsky AP, Duyn JH.

IEEE Trans Med Imaging. 2009 Apr;28(4):551-4. doi: 10.1109/TMI.2008.2006523.

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