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Items: 19

1.

Cardiac morphofunctional characteristics of transgenic rats with overexpression of the bradykinin B1 receptor in the endothelium.

Levy RF, Serra AJ, Antonio EL, Dos Santos L, Bocalini DS, Pesquero JB, Bader M, Merino VF, de Oliveira HA, de Arruda Veiga EC, Silva JA Jr, Tucci PJ.

Physiol Res. 2017 Dec 20;66(6):925-932. Epub 2017 Sep 22.

2.

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.

Sengupta S, Nagalingam A, Muniraj N, Bonner MY, Mistriotis P, Afthinos A, Kuppusamy P, Lanoue D, Cho S, Korangath P, Shriver M, Begum A, Merino VF, Huang CY, Arbiser JL, Matsui W, Győrffy B, Konstantopoulos K, Sukumar S, Marignani PA, Saxena NK, Sharma D.

Oncogene. 2017 Oct 12;36(41):5709-5721. doi: 10.1038/onc.2017.164. Epub 2017 Jun 5.

3.

Inhibitors of STAT3, β-catenin, and IGF-1R sensitize mouse PIK3CA-mutant breast cancer to PI3K inhibitors.

Merino VF, Cho S, Liang X, Park S, Jin K, Chen Q, Pan D, Zahnow CA, Rein AR, Sukumar S.

Mol Oncol. 2017 May;11(5):552-566. doi: 10.1002/1878-0261.12053. Epub 2017 Apr 6.

4.

HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24.

Teo WW, Merino VF, Cho S, Korangath P, Liang X, Wu RC, Neumann NM, Ewald AJ, Sukumar S.

Oncogene. 2016 Oct 20;35(42):5539-5551. doi: 10.1038/onc.2016.95. Epub 2016 May 9.

5.

Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer.

Merino VF, Nguyen N, Jin K, Sadik H, Cho S, Korangath P, Han L, Foster YMN, Zhou XC, Zhang Z, Connolly RM, Stearns V, Ali SZ, Adams C, Chen Q, Pan D, Huso DL, Ordentlich P, Brodie A, Sukumar S.

Cancer Res. 2016 Apr 1;76(7):2013-2024. doi: 10.1158/0008-5472.CAN-15-1619. Epub 2016 Jan 19.

6.

Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics.

Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M, Clark J, Herlihy W, Lin SJ, Chew G, Thompson EW, Greene-Colozzi A, Richardson AL, Rosson GD, Pike M, Garber JE, Nikolsky Y, Blum JL, Au A, Hwang ES, Tamimi RM, Michor F, Haviv I, Liu XS, Sukumar S, Polyak K.

Cell Stem Cell. 2013 Jul 3;13(1):117-30. doi: 10.1016/j.stem.2013.05.004. Epub 2013 Jun 13.

7.

Evidence that kinin B2 receptor expression is upregulated by endothelial overexpression of B1 receptors.

Rodrigues ES, Silva RF, Martin RP, Oliveira SM, Nakaie CR, Sabatini RA, Merino VF, Pesquero JB, Bader M, Shimuta SI.

Peptides. 2013 Apr;42:1-7. doi: 10.1016/j.peptides.2013.01.002. Epub 2013 Jan 8.

8.

Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence.

Fackler MJ, Umbricht CB, Williams D, Argani P, Cruz LA, Merino VF, Teo WW, Zhang Z, Huang P, Visvananthan K, Marks J, Ethier S, Gray JW, Wolff AC, Cope LM, Sukumar S.

Cancer Res. 2011 Oct 1;71(19):6195-207. doi: 10.1158/0008-5472.CAN-11-1630. Epub 2011 Aug 8.

9.

Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium.

Maruyama R, Choudhury S, Kowalczyk A, Bessarabova M, Beresford-Smith B, Conway T, Kaspi A, Wu Z, Nikolskaya T, Merino VF, Lo PK, Liu XS, Nikolsky Y, Sukumar S, Haviv I, Polyak K.

PLoS Genet. 2011 Apr;7(4):e1001369. doi: 10.1371/journal.pgen.1001369. Epub 2011 Apr 21.

10.

Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E.

Merino VF, Todiras M, Mori MA, Sales VM, Fonseca RG, Saul V, Tenner K, Bader M, Pesquero JB.

J Mol Med (Berl). 2009 Oct;87(10):953-63. doi: 10.1007/s00109-009-0501-0. Epub 2009 Jul 18.

PMID:
19618151
11.

Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice.

Xi L, Das A, Zhao ZQ, Merino VF, Bader M, Kukreja RC.

Circulation. 2008 Sep 30;118(14 Suppl):S32-7. doi: 10.1161/CIRCULATIONAHA.107.752865.

12.

Increased susceptibility to endotoxic shock in transgenic rats with endothelial overexpression of kinin B(1) receptors.

Merino VF, Todiras M, Campos LA, Saul V, Popova E, Baltatu OC, Pesquero JB, Bader M.

J Mol Med (Berl). 2008 Jul;86(7):791-8. doi: 10.1007/s00109-008-0345-z. Epub 2008 Apr 19.

PMID:
18425495
13.

Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.

Mori MA, Araújo RC, Reis FC, Sgai DG, Fonseca RG, Barros CC, Merino VF, Passadore M, Barbosa AM, Ferrari B, Carayon P, Castro CH, Shimuta SI, Luz J, Bascands JL, Schanstra JP, Even PC, Oliveira SM, Bader M, Pesquero JB.

Diabetes. 2008 Jun;57(6):1491-500. doi: 10.2337/db07-1508. Epub 2008 Mar 10.

14.

Mice deficient for both kinin receptors are normotensive and protected from endotoxin-induced hypotension.

Cayla C, Todiras M, Iliescu R, Saul VV, Gross V, Pilz B, Chai G, Merino VF, Pesquero JB, Baltatu OC, Bader M.

FASEB J. 2007 Jun;21(8):1689-98. Epub 2007 Feb 8.

PMID:
17289925
15.

Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function.

Araújo RC, Mori MA, Merino VF, Bascands JL, Schanstra JP, Zollner RL, Villela CA, Nakaie CR, Paiva AC, Pesquero JL, Bader M, Pesquero JB.

Biol Chem. 2006 Apr;387(4):431-6.

PMID:
16606341
16.

Molecular structure and transcriptional regulation by nuclear factor-kappaB of the mouse kinin B1 receptor gene.

Merino VF, Silva JA Jr, Araújo RC, Avellar MC, Bascands JL, Schanstra JP, Paiva AC, Bader M, Pesquero JB.

Biol Chem. 2005 Jun;386(6):515-22.

PMID:
16006238
17.

Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice.

Gabra BH, Merino VF, Bader M, Pesquero JB, Sirois P.

Regul Pept. 2005 Apr 15;127(1-3):245-8.

PMID:
15680494
18.

Structure of the mammalian kinin receptor gene locus.

Cayla C, Merino VF, Cabrini DA, Silva JA Jr, Pesquero JB, Bader M.

Int Immunopharmacol. 2002 Dec;2(13-14):1721-7. Review.

PMID:
12489785
19.

Molecular and pharmacological evidence for modulation of kinin B(1) receptor expression by endogenous glucocorticoids hormones in rats.

Cabrini DA, Campos MM, Tratsk KS, Merino VF, Silva JA Jr, Souza GE, Avellar MC, Pesquero JB, Calixto JB.

Br J Pharmacol. 2001 Jan;132(2):567-77.

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