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Items: 5

1.

Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression.

Liu W, Meridew JA, Aravamudhan A, Ligresti G, Tschumperlin DJ, Tan Q.

Respir Res. 2019 Dec 11;20(1):281. doi: 10.1186/s12931-019-1253-1.

2.

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.

Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ.

Sci Transl Med. 2019 Oct 30;11(516). pii: eaau6296. doi: 10.1126/scitranslmed.aau6296.

PMID:
31666402
3.

PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state.

Caporarello N, Meridew JA, Jones DL, Tan Q, Haak AJ, Choi KM, Manlove LJ, Prakash YS, Tschumperlin DJ, Ligresti G.

Thorax. 2019 Aug;74(8):749-760. doi: 10.1136/thoraxjnl-2019-213064. Epub 2019 Jun 10.

4.

CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.

Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ.

JCI Insight. 2019 May 16;5. pii: 127111. doi: 10.1172/jci.insight.127111.

5.

Nascent Lung Organoids Reveal Epithelium- and Bone Morphogenetic Protein-mediated Suppression of Fibroblast Activation.

Tan Q, Ma XY, Liu W, Meridew JA, Jones DL, Haak AJ, Sicard D, Ligresti G, Tschumperlin DJ.

Am J Respir Cell Mol Biol. 2019 Nov;61(5):607-619. doi: 10.1165/rcmb.2018-0390OC.

PMID:
31050552

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