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Epidermal development requires ninein for spindle orientation and cortical microtubule organization.

Lecland N, Hsu CY, Chemin C, Merdes A, Bierkamp C.

Life Sci Alliance. 2019 Mar 28;2(2). pii: e201900373. doi: 10.26508/lsa.201900373. Print 2019 Apr.


Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis.

Hsu CY, Lecland N, Pendaries V, Viodé C, Redoulès D, Paul C, Merdes A, Simon M, Bierkamp C.

J Dermatol Sci. 2018 Jul;91(1):87-96. doi: 10.1016/j.jdermsci.2018.04.008. Epub 2018 Apr 18.


Assembly and regulation of γ-tubulin complexes.

Farache D, Emorine L, Haren L, Merdes A.

Open Biol. 2018 Mar;8(3). pii: 170266. doi: 10.1098/rsob.170266. Review.


Centriolar satellites prevent uncontrolled degradation of centrosome proteins: a speculative review.

Lecland N, Merdes A.

Cell Stress. 2018 Jan 24;2(2):20-24. doi: 10.15698/cst2018.02.122.


NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex.

Cukier CD, Tourdes A, El-Mazouni D, Guillet V, Nomme J, Mourey L, Milon A, Merdes A, Gervais V.

Protein Sci. 2017 Nov;26(11):2240-2248. doi: 10.1002/pro.3282. Epub 2017 Sep 27.


Nuclear alignment in myotubes requires centrosome proteins recruited by nesprin-1.

Espigat-Georger A, Dyachuk V, Chemin C, Emorine L, Merdes A.

J Cell Sci. 2016 Nov 15;129(22):4227-4237. Epub 2016 Oct 6.


Functional Analysis of γ-Tubulin Complex Proteins Indicates Specific Lateral Association via Their N-terminal Domains.

Farache D, Jauneau A, Chemin C, Chartrain M, Rémy MH, Merdes A, Haren L.

J Biol Chem. 2016 Oct 28;291(44):23112-23125. Epub 2016 Sep 22.


Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network.

Sana TG, Baumann C, Merdes A, Soscia C, Rattei T, Hachani A, Jones C, Bennett KL, Filloux A, Superti-Furga G, Voulhoux R, Bleves S.

MBio. 2015 Jun 2;6(3):e00712. doi: 10.1128/mBio.00712-15.


Mutations in TUBGCP4 alter microtubule organization via the γ-tubulin ring complex in autosomal-recessive microcephaly with chorioretinopathy.

Scheidecker S, Etard C, Haren L, Stoetzel C, Hull S, Arno G, Plagnol V, Drunat S, Passemard S, Toutain A, Obringer C, Koob M, Geoffroy V, Marion V, Strähle U, Ostergaard P, Verloes A, Merdes A, Moore AT, Dollfus H.

Am J Hum Genet. 2015 Apr 2;96(4):666-74. doi: 10.1016/j.ajhg.2015.02.011. Epub 2015 Mar 26.


γ-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioning.

Bouissou A, Vérollet C, de Forges H, Haren L, Bellaïche Y, Perez F, Merdes A, Raynaud-Messina B.

EMBO J. 2014 Jan 13;33(2):114-28. doi: 10.1002/embj.201385967.


A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis.

Villumsen BH, Danielsen JR, Povlsen L, Sylvestersen KB, Merdes A, Beli P, Yang YG, Choudhary C, Nielsen ML, Mailand N, Bekker-Jensen S.

EMBO J. 2013 Nov 27;32(23):3029-40. doi: 10.1038/emboj.2013.223. Epub 2013 Oct 11.


Virtual and biophysical screening targeting the γ-tubulin complex--a new target for the inhibition of microtubule nucleation.

Cala O, Remy MH, Guillet V, Merdes A, Mourey L, Milon A, Czaplicki G.

PLoS One. 2013 May 15;8(5):e63908. doi: 10.1371/journal.pone.0063908. Print 2013.


Assembly of gamma-tubulin ring complexes: implications for cell biology and disease.

Remy MH, Merdes A, Gregory-Pauron L.

Prog Mol Biol Transl Sci. 2013;117:511-30. doi: 10.1016/B978-0-12-386931-9.00019-2. Review.


Microtubule nucleation by γ-tubulin complexes.

Kollman JM, Merdes A, Mourey L, Agard DA.

Nat Rev Mol Cell Biol. 2011 Oct 12;12(11):709-21. doi: 10.1038/nrm3209. Review.


Kinetochore microtubules, analyzed by correlated light and immunoelectron microscopy.

Merdes A, De Mey J.

Methods Mol Biol. 2011;777:209-21. doi: 10.1007/978-1-61779-252-6_15.


A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain.

Puram SV, Kim AH, Ikeuchi Y, Wilson-Grady JT, Merdes A, Gygi SP, Bonni A.

Nat Neurosci. 2011 Jul 3;14(8):973-83. doi: 10.1038/nn.2857.


Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation.

Guillet V, Knibiehler M, Gregory-Pauron L, Remy MH, Chemin C, Raynaud-Messina B, Bon C, Kollman JM, Agard DA, Merdes A, Mourey L.

Nat Struct Mol Biol. 2011 Jul 3;18(8):915-9. doi: 10.1038/nsmb.2083.


A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells.

Peyre E, Jaouen F, Saadaoui M, Haren L, Merdes A, Durbec P, Morin X.

J Cell Biol. 2011 Apr 4;193(1):141-54. doi: 10.1083/jcb.201101039. Epub 2011 Mar 28.


Nuclei of non-muscle cells bind centrosome proteins upon fusion with differentiating myoblasts.

Fant X, Srsen V, Espigat-Georger A, Merdes A.

PLoS One. 2009 Dec 14;4(12):e8303. doi: 10.1371/journal.pone.0008303.


{gamma}-Tubulin ring complexes regulate microtubule plus end dynamics.

Bouissou A, Vérollet C, Sousa A, Sampaio P, Wright M, Sunkel CE, Merdes A, Raynaud-Messina B.

J Cell Biol. 2009 Nov 2;187(3):327-34. doi: 10.1083/jcb.200905060. Epub 2009 Oct 26.


NuMA is required for proper spindle assembly and chromosome alignment in prometaphase.

Haren L, Gnadt N, Wright M, Merdes A.

BMC Res Notes. 2009 Apr 28;2:64. doi: 10.1186/1756-0500-2-64.


Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation.

Srsen V, Fant X, Heald R, Rabouille C, Merdes A.

BMC Cell Biol. 2009 Apr 21;10:28. doi: 10.1186/1471-2121-10-28.


Stability of the small gamma-tubulin complex requires HCA66, a protein of the centrosome and the nucleolus.

Fant X, Gnadt N, Haren L, Merdes A.

J Cell Sci. 2009 Apr 15;122(Pt 8):1134-44. doi: 10.1242/jcs.035238. Epub 2009 Mar 19.


The centrosome protein NEDD1 as a potential pharmacological target to induce cell cycle arrest.

Tillement V, Haren L, Roullet N, Etievant C, Merdes A.

Mol Cancer. 2009 Feb 25;8:10. doi: 10.1186/1476-4598-8-10.


Spindle assembly defects leading to the formation of a monopolar mitotic apparatus.

Tillement V, Remy MH, Raynaud-Messina B, Mazzolini L, Haren L, Merdes A.

Biol Cell. 2009 Jan;101(1):1-11. doi: 10.1042/BC20070162. Review.


Inhibition of proteasome activity impairs centrosome-dependent microtubule nucleation and organization.

Didier C, Merdes A, Gairin JE, Jabrane-Ferrat N.

Mol Biol Cell. 2008 Mar;19(3):1220-9. Epub 2007 Dec 19.


A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK.

Cell. 2007 Jun 15;129(6):1201-13.


Rational for a minimum data set for clinical trials with geriatric patients.

Keime-Guibert F, Abellan G, Nourhashemi F, Tsouderos Y, Merdes A, Vellas B.

J Nutr Health Aging. 2007 May-Jun;11(3):273-7. No abstract available.


DNA damage induces Chk1-dependent centrosome amplification.

Bourke E, Dodson H, Merdes A, Cuffe L, Zachos G, Walker M, Gillespie D, Morrison CG.

EMBO Rep. 2007 Jun;8(6):603-9. Epub 2007 Apr 27.


Gamma-tubulin complexes and microtubule organization.

Raynaud-Messina B, Merdes A.

Curr Opin Cell Biol. 2007 Feb;19(1):24-30. Epub 2006 Dec 18. Review.


The centrosome and cell proliferation.

Srsen V, Merdes A.

Cell Div. 2006 Nov 16;1:26.


Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle.

Srsen V, Gnadt N, Dammermann A, Merdes A.

J Cell Biol. 2006 Aug 28;174(5):625-30.


NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly.

Haren L, Remy MH, Bazin I, Callebaut I, Wright M, Merdes A.

J Cell Biol. 2006 Feb 13;172(4):505-15. Epub 2006 Feb 6.


Dynamic recruitment of Nek2 kinase to the centrosome involves microtubules, PCM-1, and localized proteasomal degradation.

Hames RS, Crookes RE, Straatman KR, Merdes A, Hayes MJ, Faragher AJ, Fry AM.

Mol Biol Cell. 2005 Apr;16(4):1711-24. Epub 2005 Jan 19.


Cell and molecular biology of spindle poles and NuMA.

Fant X, Merdes A, Haren L.

Int Rev Cytol. 2004;238:1-57. Review.


Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

Dodson H, Bourke E, Jeffers LJ, Vagnarelli P, Sonoda E, Takeda S, Earnshaw WC, Merdes A, Morrison C.

EMBO J. 2004 Oct 1;23(19):3864-73. Epub 2004 Sep 9.


Alzheimer disease without neocortical neurofibrillary tangles: "a second look".

Tiraboschi P, Sabbagh MN, Hansen LA, Salmon DP, Merdes A, Gamst A, Masliah E, Alford M, Thal LJ, Corey-Bloom J.

Neurology. 2004 Apr 13;62(7):1141-7.


Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies.

Merdes AR, Hansen LA, Jeste DV, Galasko D, Hofstetter CR, Ho GJ, Thal LJ, Corey-Bloom J.

Neurology. 2003 May 27;60(10):1586-90.


Assembly of centrosomal proteins and microtubule organization depends on PCM-1.

Dammermann A, Merdes A.

J Cell Biol. 2002 Oct 28;159(2):255-66. Epub 2002 Oct 28.


Early and widespread cholinergic losses differentiate dementia with Lewy bodies from Alzheimer disease.

Tiraboschi P, Hansen LA, Alford M, Merdes A, Masliah E, Thal LJ, Corey-Bloom J.

Arch Gen Psychiatry. 2002 Oct;59(10):946-51.


The carboxy-terminus of protein 4.1r resembles Beta-tubulin.

Fant X, Merdes A.

Cell Biol Int. 2002;26(4):371-7.


Role of importin-beta in coupling Ran to downstream targets in microtubule assembly.

Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y.

Science. 2001 Jan 26;291(5504):653-6.


Formation of spindle poles by dynein/dynactin-dependent transport of NuMA.

Merdes A, Heald R, Samejima K, Earnshaw WC, Cleveland DW.

J Cell Biol. 2000 May 15;149(4):851-62.


The role of NuMA in the interphase nucleus.

Merdes A, Cleveland DW.

J Cell Sci. 1998 Jan;111 ( Pt 1):71-9.


Pathways of spindle pole formation: different mechanisms; conserved components.

Merdes A, Cleveland DW.

J Cell Biol. 1997 Sep 8;138(5):953-6. Review. No abstract available.


A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly.

Merdes A, Ramyar K, Vechio JD, Cleveland DW.

Cell. 1996 Nov 1;87(3):447-58.


Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma.

Schlegel J, Merdes A, Stumm G, Albert FK, Forsting M, Hynes N, Kiessling M.

Int J Cancer. 1994 Jan 2;56(1):72-7.


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