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Items: 22


A Kinetic Study of the Replacement by Site Saturation Mutagenesis of Residue 119 in NDM-1 Metallo-β-Lactamase.

Marcoccia F, Mercuri PS, Galleni M, Celenza G, Amicosante G, Perilli M.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e02541-17. doi: 10.1128/AAC.02541-17. Print 2018 Aug.


P174E Substitution in GES-1 and GES-5 β-Lactamases Improves Catalytic Efficiency toward Carbapenems.

Piccirilli A, Mercuri PS, Galleni M, Aschi M, Matagne A, Amicosante G, Perilli M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e01851-17. doi: 10.1128/AAC.01851-17. Print 2018 May.


Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems.

Bottoni C, Perilli M, Marcoccia F, Piccirilli A, Pellegrini C, Colapietro M, Sabatini A, Celenza G, Kerff F, Amicosante G, Galleni M, Mercuri PS.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):3123-6. doi: 10.1128/AAC.01703-15. Print 2016 May.


Kinetic Study of Laboratory Mutants of NDM-1 Metallo-β-Lactamase and the Importance of an Isoleucine at Position 35.

Marcoccia F, Bottoni C, Sabatini A, Colapietro M, Mercuri PS, Galleni M, Kerff F, Matagne A, Celenza G, Amicosante G, Perilli M.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2366-72. doi: 10.1128/AAC.00531-15. Print 2016 Apr.


Study of a Natural Mutant SHV-Type β -Lactamase, SHV-104, from Klebsiella pneumoniae.

Ben Achour N, Belhadj O, Galleni M, Ben Moussa M, Mercuri PS.

Int J Microbiol. 2014;2014:548656. doi: 10.1155/2014/548656. Epub 2014 May 13.


R164H and V240H replacements by site-directed mutagenesis of TEM-149 extended-spectrum β-lactamase: kinetic analysis of TEM-149H240 and TEM-149H164-H240 laboratory mutants.

Perilli M, Celenza G, Mercuri PS, Galleni M, Pellegrini C, Segatore B, Amicosante G.

Antimicrob Agents Chemother. 2013 Feb;57(2):1047-9. doi: 10.1128/AAC.01268-12. Epub 2012 Nov 26.


Differential proteomic analysis of the response of Stenotrophomonas maltophilia to imipenem.

Van Oudenhove L, De Vriendt K, Van Beeumen J, Mercuri PS, Devreese B.

Appl Microbiol Biotechnol. 2012 Aug;95(3):717-33. doi: 10.1007/s00253-012-4167-0. Epub 2012 Jun 2.


Emergence and dominance of CTX-M-15 extended spectrum beta-lactamase among Escherichia coli isolates from children.

Réjiba S, Mercuri PS, Power P, Kechrid A.

Microb Drug Resist. 2011 Jun;17(2):135-40. doi: 10.1089/mdr.2010.0098. Epub 2011 Feb 2.


Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases.

Lassaux P, Hamel M, Gulea M, Delbrück H, Mercuri PS, Horsfall L, Dehareng D, Kupper M, Frère JM, Hoffmann K, Galleni M, Bebrone C.

J Med Chem. 2010 Jul 8;53(13):4862-76. doi: 10.1021/jm100213c.


Characterization of a novel extended-spectrum TEM-type beta-lactamase, TEM-164, in a clinical strain of Klebsiella pneumoniae in Tunisia.

Ben Achour N, Mercuri PS, Ben Moussa M, Galleni M, Belhadj O.

Microb Drug Resist. 2009 Sep;15(3):195-9. doi: 10.1089/mdr.2009.0900.


Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location.

Pellegrini C, Mercuri PS, Celenza G, Galleni M, Segatore B, Sacchetti E, Volpe R, Amicosante G, Perilli M.

J Antimicrob Chemother. 2009 May;63(5):901-8. doi: 10.1093/jac/dkp061. Epub 2009 Mar 6.


Characterization of the cattle serum antibody responses against TEM beta-lactamase and the nonimmunogenic Escherichia coli heat-stable enterotoxin (STaI).

Zervosen A, Saegerman C, Antoniotti I, Robert B, Ruth N, Collard A, Schynts F, Galleni M, Mercuri PS.

FEMS Immunol Med Microbiol. 2008 Dec;54(3):319-29. doi: 10.1111/j.1574-695X.2008.00482.x.


First detection of CTX-M-28 in a Tunisian hospital from a cefotaxime-resistant Klebsiella pneumoniae strain.

Ben Achour N, Mercuri PS, Power P, Belhadj C, Ben Moussa M, Galleni M, Belhadj O.

Pathol Biol (Paris). 2009 Jul;57(5):343-8. doi: 10.1016/j.patbio.2008.07.016. Epub 2008 Oct 1.


Synthesis of copolymer brushes endowed with adhesion to stainless steel surfaces and antibacterial properties by controlled nitroxide-mediated radical polymerization.

Ignatova M, Voccia S, Gilbert B, Markova N, Mercuri PS, Galleni M, Sciannamea V, Lenoir S, Cossement D, Gouttebaron R, Jérôme R, Jérôme C.

Langmuir. 2004 Nov 23;20(24):10718-26.


Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis.

Mercuri PS, García-Sáez I, De Vriendt K, Thamm I, Devreese B, Van Beeumen J, Dideberg O, Rossolini GM, Frère JM, Galleni M.

J Biol Chem. 2004 Aug 6;279(32):33630-8. Epub 2004 May 24.


Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.

García-Sáez I, Mercuri PS, Papamicael C, Kahn R, Frère JM, Galleni M, Rossolini GM, Dideberg O.

J Mol Biol. 2003 Jan 24;325(4):651-60.


Clonal diversity and metallo-beta-lactamase production in clinical isolates of Stenotrophomonas maltophilia.

Mercuri PS, Ishii Y, Ma L, Rossolini GM, Luzzaro F, Amicosante G, Franceschini N, Frere JM, Galleni M.

Microb Drug Resist. 2002 Fall;8(3):193-200.


Inactivation of Aeromonas hydrophila metallo-beta-lactamase by cephamycins and moxalactam.

Zervosen A, Valladares MH, Devreese B, Prosperi-Meys C, Adolph HW, Mercuri PS, Vanhove M, Amicosante G, van Beeumen J, Frère JM, Galleni M.

Eur J Biochem. 2001 Jul;268(13):3840-50.


Biochemical characterization of the FEZ-1 metallo-beta-lactamase of Legionella gormanii ATCC 33297T produced in Escherichia coli.

Mercuri PS, Bouillenne F, Boschi L, Lamotte-Brasseur J, Amicosante G, Devreese B, van Beeumen J, Frère JM, Rossolini GM, Galleni M.

Antimicrob Agents Chemother. 2001 Apr;45(4):1254-62.


The Legionella (Fluoribacter) gormanii metallo-beta-lactamase: a new member of the highly divergent lineage of molecular-subclass B3 beta-lactamases.

Boschi L, Mercuri PS, Riccio ML, Amicosante G, Galleni M, Frère JM, Rossolini GM.

Antimicrob Agents Chemother. 2000 Jun;44(6):1538-43.


Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile.

Rossolini GM, Franceschini N, Riccio ML, Mercuri PS, Perilli M, Galleni M, Frere JM, Amicosante G.

Biochem J. 1998 May 15;332 ( Pt 1):145-52.


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