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Items: 1 to 50 of 69

1.

Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalis.

Sundaram K, Miller DP, Kumar A, Teng Y, Sayed M, Mu J, Lei C, Sriwastva MK, Zhang L, Jun Y, Merchant ML, He L, Fang Y, Zhang S, Zhang X, Park JW, Lamont RJ, Zhang HG.

iScience. 2019 Oct 21;21:308-327. doi: 10.1016/j.isci.2019.10.032. [Epub ahead of print]

2.

Evaluating the Effects of Fibrinogen αC Mutations on the Ability of Factor XIII to Crosslink the Reactive αC Glutamines (Q237, Q328, Q366).

Mouapi KN, Wagner LJ, Stephens CA, Hindi MM, Wilkey DW, Merchant ML, Maurer MC.

Thromb Haemost. 2019 Jul;119(7):1048-1057. doi: 10.1055/s-0039-1687875. Epub 2019 May 5.

PMID:
31055797
3.

Proteomic Analysis Reveals Novel Mechanisms by Which Polychlorinated Biphenyls Compromise the Liver Promoting Diet-Induced Steatohepatitis.

Hardesty JE, Wahlang B, Falkner KC, Shi H, Jin J, Zhou Y, Wilkey DW, Merchant ML, Watson CT, Feng W, Morris AJ, Hennig B, Prough RA, Cave MC.

J Proteome Res. 2019 Apr 5;18(4):1582-1594. doi: 10.1021/acs.jproteome.8b00886. Epub 2019 Mar 15.

PMID:
30807179
4.

Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota.

Teng Y, Ren Y, Sayed M, Hu X, Lei C, Kumar A, Hutchins E, Mu J, Deng Z, Luo C, Sundaram K, Sriwastva MK, Zhang L, Hsieh M, Reiman R, Haribabu B, Yan J, Jala VR, Miller DM, Van Keuren-Jensen K, Merchant ML, McClain CJ, Park JW, Egilmez NK, Zhang HG.

Cell Host Microbe. 2018 Nov 14;24(5):637-652.e8. doi: 10.1016/j.chom.2018.10.001. Epub 2018 Oct 25.

PMID:
30449315
5.

Precision medicine in lupus nephritis: can biomarkers get us there?

Caster DJ, Merchant ML, Klein JB, Powell DW.

Transl Res. 2018 Nov;201:26-39. doi: 10.1016/j.trsl.2018.08.002. Epub 2018 Aug 10. Review.

6.

Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes.

Looker HC, Merchant ML, Rane MJ, Nelson RG, Kimmel PL, Rovin BH, Klein JB, Mauer M; CKD Biomarkers Consortium.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1484-F1492. doi: 10.1152/ajprenal.00183.2018. Epub 2018 Aug 22.

7.

Biomarker enhanced risk prediction for development of AKI after cardiac surgery.

Merchant ML, Brier ME, Slaughter MS, Klein JB, McLeish KR.

BMC Nephrol. 2018 May 2;19(1):102. doi: 10.1186/s12882-018-0902-9.

8.

Deficiency of aldose reductase exacerbates early pressure overload-induced cardiac dysfunction and autophagy in mice.

Baba SP, Zhang D, Singh M, Dassanayaka S, Xie Z, Jagatheesan G, Zhao J, Schmidtke VK, Brittian KR, Merchant ML, Conklin DJ, Jones SP, Bhatnagar A.

J Mol Cell Cardiol. 2018 May;118:183-192. doi: 10.1016/j.yjmcc.2018.04.002. Epub 2018 Apr 5.

9.

Proteomics reveals novel protein associations with early endosomes in an epidermal growth factor-dependent manner.

Gosney JA, Wilkey DW, Merchant ML, Ceresa BP.

J Biol Chem. 2018 Apr 20;293(16):5895-5908. doi: 10.1074/jbc.RA117.000632. Epub 2018 Mar 9.

10.

Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery.

Merchant ML, Rood IM, Deegens JKJ, Klein JB.

Nat Rev Nephrol. 2017 Dec;13(12):731-749. doi: 10.1038/nrneph.2017.148. Epub 2017 Oct 30. Review.

11.

Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins.

Hudson SV, Dolin CE, Poole LG, Massey VL, Wilkey D, Beier JI, Merchant ML, Frieboes HB, Arteel GE.

Sci Rep. 2017 Sep 29;7(1):12444. doi: 10.1038/s41598-017-12691-y.

12.

Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus.

Wheelock KM, Cai J, Looker HC, Merchant ML, Nelson RG, Fufaa GD, Weil EJ, Feldman HI, Vasan RS, Kimmel PL, Rovin BH, Mauer M, Klein JB; CKD Biomarkers Consortium.

PLoS One. 2017 Jul 10;12(7):e0180964. doi: 10.1371/journal.pone.0180964. eCollection 2017.

13.

Select human cancer mutants of NRMT1 alter its catalytic activity and decrease N-terminal trimethylation.

Shields KM, Tooley JG, Petkowski JJ, Wilkey DW, Garbett NC, Merchant ML, Cheng A, Schaner Tooley CE.

Protein Sci. 2017 Aug;26(8):1639-1652. doi: 10.1002/pro.3202. Epub 2017 Jun 11.

14.

Loss of NHERF-1 expression prevents dopamine-mediated Na-K-ATPase regulation in renal proximal tubule cells from rat models of hypertension: aged F344 rats and spontaneously hypertensive rats.

Barati MT, Ketchem CJ, Merchant ML, Kusiak WB, Jose PA, Weinman EJ, LeBlanc AJ, Lederer ED, Khundmiri SJ.

Am J Physiol Cell Physiol. 2017 Aug 1;313(2):C197-C206. doi: 10.1152/ajpcell.00219.2016. Epub 2017 May 17.

15.

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression.

Teng Y, Ren Y, Hu X, Mu J, Samykutty A, Zhuang X, Deng Z, Kumar A, Zhang L, Merchant ML, Yan J, Miller DM, Zhang HG.

Nat Commun. 2017 Feb 17;8:14448. doi: 10.1038/ncomms14448.

16.

Frontline Science: Tumor necrosis factor-α stimulation and priming of human neutrophil granule exocytosis.

McLeish KR, Merchant ML, Creed TM, Tandon S, Barati MT, Uriarte SM, Ward RA.

J Leukoc Biol. 2017 Jul;102(1):19-29. doi: 10.1189/jlb.3HI0716-293RR. Epub 2017 Jan 17.

17.

The hepatic "matrisome" responds dynamically to injury: Characterization of transitional changes to the extracellular matrix in mice.

Massey VL, Dolin CE, Poole LG, Hudson SV, Siow DL, Brock GN, Merchant ML, Wilkey DW, Arteel GE.

Hepatology. 2017 Mar;65(3):969-982. doi: 10.1002/hep.28918. Epub 2016 Dec 30.

18.

Characterization of glomerular extracellular matrix by proteomic analysis of laser-captured microdissected glomeruli.

Hobeika L, Barati MT, Caster DJ, McLeish KR, Merchant ML.

Kidney Int. 2017 Feb;91(2):501-511. doi: 10.1016/j.kint.2016.09.044. Epub 2016 Dec 15.

19.

Over-expression of insulin-response element binding protein-1 (IRE-BP1) in mouse pancreatic islets increases expression of RACK1 and TCTP: Beta cell markers of high glucose sensitivity.

Villafuerte BC, Barati MT, Rane MJ, Isaacs S, Li M, Wilkey DW, Merchant ML.

Biochim Biophys Acta Proteins Proteom. 2017 Feb;1865(2):186-194. doi: 10.1016/j.bbapap.2016.10.015. Epub 2016 Nov 3.

20.

Evidence that vitronectin is a potent migration-enhancing factor for cancer cells chaperoned by fibrinogen: a novel view of the metastasis of cancer cells to low-fibrinogen lymphatics and body cavities.

Schneider G, Bryndza E, Poniewierska-Baran A, Serwin K, Suszynska M, Sellers ZP, Merchant ML, Kaliappan A, Ratajczak J, Kucia M, Garbett NC, Ratajczak MZ.

Oncotarget. 2016 Oct 25;7(43):69829-69843. doi: 10.18632/oncotarget.12003.

21.

Proteomics Analysis Reveals Novel RASSF2 Interaction Partners.

Barnoud T, Wilkey DW, Merchant ML, Clark JA, Donninger H.

Cancers (Basel). 2016 Mar 16;8(3). pii: E37. doi: 10.3390/cancers8030037.

22.

Influence of Acute High Glucose on Protein Abundance Changes in Murine Glomerular Mesangial Cells.

Barati MT, Gould JC, Salyer SA, Isaacs S, Wilkey DW, Merchant ML.

J Diabetes Res. 2016;2016:3537863. doi: 10.1155/2016/3537863. Epub 2015 Dec 29.

23.

Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA.

Murray RD, Merchant ML, Hardin E, Clark B, Khundmiri SJ, Lederer ED.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C205-15. doi: 10.1152/ajpcell.00192.2015. Epub 2015 Nov 25.

24.

Increased expression of lysosome membrane protein 2 in glomeruli of patients with idiopathic membranous nephropathy.

Rood IM, Merchant ML, Wilkey DW, Zhang T, Zabrouskov V, van der Vlag J, Dijkman HB, Willemsen BK, Wetzels JF, Klein JB, Deegens JK.

Proteomics. 2015 Nov;15(21):3722-30. doi: 10.1002/pmic.201500127. Epub 2015 Sep 28.

PMID:
26304790
25.

Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes.

Lőrincz ÁM, Schütte M, Timár CI, Veres DS, Kittel Á, McLeish KR, Merchant ML, Ligeti E.

J Leukoc Biol. 2015 Oct;98(4):583-9. doi: 10.1189/jlb.3VMA1014-514R. Epub 2015 May 18.

PMID:
25986013
26.

Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice.

Conklin DJ, Haberzettl P, Jagatheesan G, Baba S, Merchant ML, Prough RA, Williams JD, Prabhu SD, Bhatnagar A.

Toxicol Appl Pharmacol. 2015 Jun 1;285(2):136-48. doi: 10.1016/j.taap.2015.03.029. Epub 2015 Apr 10.

27.

Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators.

Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ.

PLoS One. 2015 Apr 7;10(4):e0121637. doi: 10.1371/journal.pone.0121637. eCollection 2015.

28.

Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis.

Caster DJ, Korte EA, Merchant ML, Klein JB, Wilkey DW, Rovin BH, Birmingham DJ, Harley JB, Cobb BL, Namjou B, McLeish KR, Powell DW.

Proteomics Clin Appl. 2015 Dec;9(11-12):1012-20. doi: 10.1002/prca.201400175. Epub 2015 Jun 12.

29.

Can the Urinary Peptidome Outperform Creatinine and Albumin to Predict Renal Function Decline?

Merchant ML.

J Am Soc Nephrol. 2015 Aug;26(8):1760-1. doi: 10.1681/ASN.2014121243. Epub 2015 Jan 14. No abstract available.

30.

Detection of cervical cancer biomarker patterns in blood plasma and urine by differential scanning calorimetry and mass spectrometry.

Garbett NC, Merchant ML, Helm CW, Jenson AB, Klein JB, Chaires JB.

PLoS One. 2014 Jan 8;9(1):e84710. doi: 10.1371/journal.pone.0084710. eCollection 2014.

31.

NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1.

Petkowski JJ, Bonsignore LA, Tooley JG, Wilkey DW, Merchant ML, Macara IG, Schaner Tooley CE.

Biochem J. 2013 Dec 15;456(3):453-62. doi: 10.1042/BJ20131163.

32.

Calorimetric analysis of the plasma proteome: identification of type 1 diabetes patients with early renal function decline.

Garbett NC, Merchant ML, Chaires JB, Klein JB.

Biochim Biophys Acta. 2013 Oct;1830(10):4675-80. doi: 10.1016/j.bbagen.2013.05.007. Epub 2013 May 10.

33.

Technical note: proteomic approaches to fundamental questions about neutrophil biology.

McLeish KR, Merchant ML, Klein JB, Ward RA.

J Leukoc Biol. 2013 Oct;94(4):683-92. doi: 10.1189/jlb.1112591. Epub 2013 Mar 7. Review.

34.

Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type 1 diabetes.

Merchant ML, Niewczas MA, Ficociello LH, Lukenbill JA, Wilkey DW, Li M, Khundmiri SJ, Warram JH, Krolewski AS, Klein JB.

Kidney Int. 2013 Jun;83(6):1177-84. doi: 10.1038/ki.2013.8. Epub 2013 Mar 6.

35.

Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats.

Uriarte SM, Rane MJ, Merchant ML, Jin S, Lentsch AB, Ward RA, McLeish KR.

Shock. 2013 Mar;39(3):286-92. doi: 10.1097/SHK.0b013e318282c9a1.

36.

Lipid peroxidation product 4-hydroxy-trans-2-nonenal causes endothelial activation by inducing endoplasmic reticulum stress.

Vladykovskaya E, Sithu SD, Haberzettl P, Wickramasinghe NS, Merchant ML, Hill BG, McCracken J, Agarwal A, Dougherty S, Gordon SA, Schuschke DA, Barski OA, O'Toole T, D'Souza SE, Bhatnagar A, Srivastava S.

J Biol Chem. 2012 Mar 30;287(14):11398-409. doi: 10.1074/jbc.M111.320416. Epub 2012 Jan 6.

37.

Elder abuse research: a systematic review.

Daly JM, Merchant ML, Jogerst GJ.

J Elder Abuse Negl. 2011 Oct;23(4):348-65. doi: 10.1080/08946566.2011.608048. Review.

38.

Primary care clinicians' perspectives on management of skin and soft tissue infections: an Iowa Research Network study.

Daly JM, Ely JW, Levy BT, Smith TC, Merchant ML, Bergus GR, Jogerst GJ.

J Rural Health. 2011 Summer;27(3):319-28. doi: 10.1111/j.1748-0361.2010.00347.x. Epub 2010 Nov 15.

PMID:
21729160
39.

Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter.

Ahmad A, Khundmiri SJ, Pribble F, Merchant ML, Ameen M, Klein JB, Levi M, Lederer ED.

Cell Physiol Biochem. 2011;27(6):703-14. doi: 10.1159/000330079. Epub 2011 Jun 17.

40.

Oncostatin M receptor β and cysteine/histidine-rich 1 are biomarkers of the response to erythropoietin in hemodialysis patients.

Merchant ML, Gaweda AE, Dailey AJ, Wilkey DW, Zhang X, Rovin BH, Klein JB, Brier ME.

Kidney Int. 2011 Mar;79(5):546-554. doi: 10.1038/ki.2010.468. Epub 2010 Dec 8.

41.

Microfiltration isolation of human urinary exosomes for characterization by MS.

Merchant ML, Powell DW, Wilkey DW, Cummins TD, Deegens JK, Rood IM, McAfee KJ, Fleischer C, Klein E, Klein JB.

Proteomics Clin Appl. 2010 Jan;4(1):84-96. doi: 10.1002/prca.200800093. Epub 2009 Nov 11.

PMID:
21137018
42.

Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation.

Luerman GC, Powell DW, Uriarte SM, Cummins TD, Merchant ML, Ward RA, McLeish KR.

Mol Cell Proteomics. 2011 Mar;10(3):M110.001552. doi: 10.1074/mcp.M110.001552. Epub 2010 Nov 19.

43.

Proteomic discovery of diabetic nephropathy biomarkers.

Merchant ML, Klein JB.

Adv Chronic Kidney Dis. 2010 Nov;17(6):480-6. doi: 10.1053/j.ackd.2010.09.001. Review.

44.

Mass spectrometry in chronic kidney disease research.

Merchant ML.

Adv Chronic Kidney Dis. 2010 Nov;17(6):455-68. doi: 10.1053/j.ackd.2010.09.003. Review.

45.

Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome.

Rood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB.

Kidney Int. 2010 Oct;78(8):810-6. doi: 10.1038/ki.2010.262. Epub 2010 Aug 4.

46.

Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells.

Holthouser KA, Mandal A, Merchant ML, Schelling JR, Delamere NA, Valdes RR Jr, Tyagi SC, Lederer ED, Khundmiri SJ.

Am J Physiol Renal Physiol. 2010 Jul;299(1):F77-90. doi: 10.1152/ajprenal.00581.2009. Epub 2010 Apr 28.

47.

The "Iowa get screened" colon cancer screening program.

Levy BT, Daly JM, Luxon B, Merchant ML, Xu Y, Levitz CE, Wilbur JK.

J Prim Care Community Health. 2010 Apr 1;1(1):43-9. doi: 10.1177/2150131909352191.

PMID:
23804068
48.

Mailed fecal-immunochemical test for colon cancer screening.

Daly JM, Levy BT, Merchant ML, Wilbur J.

J Community Health. 2010 Jun;35(3):235-9. doi: 10.1007/s10900-010-9227-8.

PMID:
20127156
49.

Colorectal cancer screening.

Daly JM, Merchant ML, Levy BT.

Am J Nurs. 2009 Oct;109(10):60-2. doi: 10.1097/01.NAJ.0000361496.60341.84. No abstract available.

PMID:
21753484
50.

Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria.

Merchant ML, Perkins BA, Boratyn GM, Ficociello LH, Wilkey DW, Barati MT, Bertram CC, Page GP, Rovin BH, Warram JH, Krolewski AS, Klein JB.

J Am Soc Nephrol. 2009 Sep;20(9):2065-74. doi: 10.1681/ASN.2008121233. Epub 2009 Jul 30.

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