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Items: 1 to 50 of 57

1.

Downregulation of Wip-1 phosphatase expression in MCF-7 breast cancer cells enhances doxorubicin-induced apoptosis through p53-mediated transcriptional activation of Bax.

Kong W, Jiang X, Mercer WE.

Cancer Biol Ther. 2009 Mar 15;8(6):555-63. doi: 10.4161/cbt.8.6.7742. Epub 2009 Mar 15.

PMID:
19242108
2.

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity.

Rallapalli R, Strachan G, Cho B, Mercer WE, Hall DJ.

J Biol Chem. 1999 Mar 19;274(12):8299-308.

3.

Checking on the cell cycle.

Mercer WE.

J Cell Biochem Suppl. 1998;30-31:50-4. Review.

PMID:
9893255
4.

Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription.

Sawaya BE, Khalili K, Mercer WE, Denisova L, Amini S.

J Biol Chem. 1998 Aug 7;273(32):20052-7.

5.

Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene.

Sevignani C, Wlodarski P, Kirillova J, Mercer WE, Danielson KG, Iozzo RV, Calabretta B.

J Clin Invest. 1998 Apr 15;101(8):1572-80.

6.

The role of p53, p21WAF1/C1PI, and bcl-2 in radioresistant colorectal carcinoma.

Palazzo JP, Kafka NJ, Grasso L, Chakrani F, Hanau C, Cuesta KH, Mercer WE.

Hum Pathol. 1997 Oct;28(10):1189-95.

PMID:
9343326
7.

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner.

Fiscella M, Zhang H, Fan S, Sakaguchi K, Shen S, Mercer WE, Vande Woude GF, O'Connor PM, Appella E.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6048-53.

8.

Pathways of p53-dependent apoptosis.

Grasso L, Mercer WE.

Vitam Horm. 1997;53:139-73. Review. No abstract available.

PMID:
9197180
9.

Immunohistochemical localization of p21(WAF1/CIP1) in normal, hyperplastic, and neoplastic uterine tissues.

Palazzo JP, Mercer WE, Kovatich AJ, McHugh M.

Hum Pathol. 1997 Jan;28(1):60-6.

PMID:
9013833
10.
11.

p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.

Zhang W, Grasso L, McClain CD, Gambel AM, Cha Y, Travali S, Deisseroth AB, Mercer WE.

Cancer Res. 1995 Feb 1;55(3):668-74.

12.

The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.

Fiscella M, Zambrano N, Ullrich SJ, Unger T, Lin D, Cho B, Mercer WE, Anderson CW, Appella E.

Oncogene. 1994 Nov;9(11):3249-57.

PMID:
7936649
13.

Constitutive expression of B-myb can bypass p53-induced Waf1/Cip1-mediated G1 arrest.

Lin D, Fiscella M, O'Connor PM, Jackman J, Chen M, Luo LL, Sala A, Travali S, Appella E, Mercer WE.

Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):10079-83.

14.

Induction of WAF1/CIP1 by a p53-independent pathway.

Michieli P, Chedid M, Lin D, Pierce JH, Mercer WE, Givol D.

Cancer Res. 1994 Jul 1;54(13):3391-5.

15.

WAF1, a potential mediator of p53 tumor suppression.

el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B.

Cell. 1993 Nov 19;75(4):817-25.

PMID:
8242752
16.

Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53.

Ullrich SJ, Sakaguchi K, Lees-Miller SP, Fiscella M, Mercer WE, Anderson CW, Appella E.

Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):5954-8.

17.

Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression.

Fiscella M, Ullrich SJ, Zambrano N, Shields MT, Lin D, Lees-Miller SP, Anderson CW, Mercer WE, Appella E.

Oncogene. 1993 Jun;8(6):1519-28.

PMID:
8502477
18.

Effects of exogenous wild-type p53 on a human lung carcinoma cell line with endogenous wild-type p53.

Noble JR, Willetts KE, Mercer WE, Reddel RR.

Exp Cell Res. 1992 Dec;203(2):297-304.

PMID:
1459195
19.

Cell cycle effects of microinjected antisense oligodeoxynucleotides to p34cdc2 kinase.

Mercer WE, Ullrich SJ, Shields MT, Lin D, Alder H.

Ann N Y Acad Sci. 1992 Oct 28;660:209-18.

PMID:
1340123
20.

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase.

Lin D, Shields MT, Ullrich SJ, Appella E, Mercer WE.

Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9210-4.

21.

The p53 tumor suppressor protein, a modulator of cell proliferation.

Ullrich SJ, Anderson CW, Mercer WE, Appella E.

J Biol Chem. 1992 Aug 5;267(22):15259-62. Review. No abstract available.

22.
23.

Cell cycle regulation and the p53 tumor suppressor protein.

Mercer WE.

Crit Rev Eukaryot Gene Expr. 1992;2(3):251-63. Review.

PMID:
1511188
24.

Computer-assisted microfluorometric detection of individual malignant bladder cells.

Gerber WL, Lenahen PJ, Kendall AR, Mercer WE.

Urology. 1991 Nov;38(5):466-72.

PMID:
1949462
25.

Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression.

Mercer WE, Shields MT, Lin D, Appella E, Ullrich SJ.

Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1958-62.

26.

Constitutively expressed c-myb abrogates the requirement for insulinlike growth factor 1 in 3T3 fibroblasts.

Travali S, Reiss K, Ferber A, Petralia S, Mercer WE, Calabretta B, Baserga R.

Mol Cell Biol. 1991 Feb;11(2):731-6.

27.

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

Mercer WE, Shields MT, Amin M, Sauve GJ, Appella E, Romano JW, Ullrich SJ.

Proc Natl Acad Sci U S A. 1990 Aug;87(16):6166-70.

28.

Wild type human p53 is antiproliferative in SV40-transformed hamster cells.

Mercer WE, Amin M, Sauve GJ, Appella E, Ullrich SJ, Romano JW.

Oncogene. 1990 Jul;5(7):973-80.

PMID:
2165234
29.

Effects of norepinephrine on neonatal rat cardiocyte growth and differentiation.

Marino TA, Walter RA, Cobb E, Palasiuk M, Parsons T, Mercer WE.

In Vitro Cell Dev Biol. 1990 Mar;26(3 Pt 1):229-36.

PMID:
1969403
30.

Effects of catecholamines on fetal rat cardiocytes in vitro.

Marino TA, Walter RA, D'Ambra K, Mercer WE.

Am J Anat. 1989 Oct;186(2):127-32.

PMID:
2816781
31.

Growth factor regulated expression of poly(A)+ binding protein messenger RNA.

Mercer WE, Jaskulski D, Shields MT.

Exp Cell Res. 1989 Apr;181(2):531-41.

PMID:
2647498
32.

Growth-related expression of a 72,000 molecular weight poly(A)+ mRNA binding protein.

Ullrich SJ, Appella E, Mercer WE.

Exp Cell Res. 1988 Oct;178(2):273-86.

PMID:
2458950
33.

Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin.

Jaskulski D, deRiel JK, Mercer WE, Calabretta B, Baserga R.

Science. 1988 Jun 10;240(4858):1544-6.

PMID:
2897717
34.

Cell cycle analysis of human peripheral blood T lymphocytes in long-term culture.

Kaczmarek L, Calabretta B, Elfenbein IB, Mercer WE.

Exp Cell Res. 1987 Nov;173(1):70-9.

PMID:
2445595
35.

TPA-induction of c-fos mRNA during the cell cycle of WI-38 human fibroblasts.

Calabretta B, Mercer WE.

Biochem Biophys Res Commun. 1987 Sep 15;147(2):716-23.

PMID:
3632695
36.

Production of transgenic mice following deoxyribonucleic acid microinjection and embryo freezing.

Petters RM, Johnson BH, Mercer WE.

Theriogenology. 1987 Mar;27(3):507-15.

PMID:
16726255
37.

Growth-dependent expression of human Mr 53,000 tumor antigen messenger RNA in normal and neoplastic cells.

Calabretta B, Kaczmarek L, Selleri L, Torelli G, Ming PM, Ming SC, Mercer WE.

Cancer Res. 1986 Nov;46(11):5738-42.

38.
39.

Load regulation of the properties of adult feline cardiocytes. The role of substrate adhesion.

Cooper G 4th, Mercer WE, Hoober JK, Gordon PR, Kent RL, Lauva IK, Marino TA.

Circ Res. 1986 May;58(5):692-705.

PMID:
3708766
40.
41.

Expression of the p53 protein during the cell cycle of human peripheral blood lymphocytes.

Mercer WE, Baserga R.

Exp Cell Res. 1985 Sep;160(1):31-46.

PMID:
3930272
42.

Cytophotometry of breast carcinoma. Acridine-orange DNA microfluorimetry with Giemsa counterstain.

Rosen S, Mercer WE.

Anal Quant Cytol Histol. 1985 Jun;7(2):159-62.

PMID:
4026947
43.

Expression of thymidine kinase and dihydrofolate reductase genes in mammalian ts mutants of the cell cycle.

Liu HT, Gibson CW, Hirschhorn RR, Rittling S, Baserga R, Mercer WE.

J Biol Chem. 1985 Mar 25;260(6):3269-74.

44.

The transformation-related p53 protein: a potential regulator of cell proliferation.

Mercer WE, Baserga R.

Prog Clin Biol Res. 1985;177:171-91. No abstract available.

PMID:
2409558
45.

Transforming potential of deletion mutants of the SV40 T antigen coding gene in Syrian hamster cells.

Hirschhorn RR, Mercer WE, Liu HT, Baserga R.

Virology. 1984 Apr 15;134(1):220-9.

PMID:
6324470
46.
47.

Microinjection of RNA polymerase II corrects the temperature-sensitive defect of tsAF8 cells.

Waechter DE, Avignolo C, Freund E, Riggenbach CM, Mercer WE, McGuire PM, Baserga R.

Mol Cell Biochem. 1984;60(1):77-82.

PMID:
6708942
48.

Cellular DNA replication is independent of the synthesis or accumulation of ribosomal RNA.

Mercer WE, Avignolo C, Galanti N, Rose KM, Hyland JK, Jacob ST, Baserga R.

Exp Cell Res. 1984 Jan;150(1):118-30.

PMID:
6692843
49.

Microinjected pBR322 stimulates cellular DNA synthesis in Swiss 3T3 cells.

Hyland JK, Hirschhorn RR, Avignolo C, Mercer WE, Ohta M, Galanti N, Jonak GJ, Baserga R.

Proc Natl Acad Sci U S A. 1984 Jan;81(2):400-4.

50.

Inhibition of SV40-induced cellular DNA synthesis by microinjection of monoclonal antibodies.

Mercer WE, Nelson D, Hyland JK, Croce CM, Baserga R.

Virology. 1983 May;127(1):149-58.

PMID:
6305012

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