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Romero-Garcia R, Erez Y, Oliver G, Owen M, Merali S, Poologaindran A, Morris RC, Price SJ, Santarius T, Suckling J, Hart MG.

World Neurosurg. 2020 Jan 17. pii: S1878-8750(20)30103-0. doi: 10.1016/j.wneu.2020.01.085. [Epub ahead of print]


The central role of protein kinase C epsilon in cyanide cardiotoxicity and its treatment.

Cheung JY, Merali S, Wang J, Zhang XQ, Song J, Merali C, Tomar D, You H, Judenherc-Haouzi A, Haouzi P.

Toxicol Sci. 2019 Jun 7. pii: kfz137. doi: 10.1093/toxsci/kfz137. [Epub ahead of print]


Novel biomarkers to assess in utero effects of maternal opioid use: First steps toward understanding short- and long-term neurodevelopmental sequelae.

Goetzl L, Thompson-Felix T, Darbinian N, Merabova N, Merali S, Merali C, Sanserino K, Tatevosian T, Fant B, Wimmer ME.

Genes Brain Behav. 2019 Jul;18(6):e12583. doi: 10.1111/gbb.12583. Epub 2019 Jun 11.


ELMO1 deficiency enhances platelet function.

Patel A, Kostyak J, Dangelmaier C, Badolia R, Bhavanasi D, Aslan JE, Merali S, Kim S, Eble JA, Goldfinger L, Kunapuli S.

Blood Adv. 2019 Feb 26;3(4):575-587. doi: 10.1182/bloodadvances.2018016444.


Experiences of people with stroke and multiple sclerosis and caregivers of a community exercise programme involving a healthcare-recreation partnership.

Merali S, Cameron JI, Barclay R, Salbach NM.

Disabil Rehabil. 2019 Jan 22:1-7. doi: 10.1080/09638288.2018.1519042. [Epub ahead of print]


Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.

Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, Bhanu NV, Simithy J, Patel B, Huang J, Raynal NJ, Garcia BA, Jacobson MA, Kadoch C, Merali S, Zhang Y, Childers W, Abou-Gharbia M, Karanicolas J, Baylin SB, Zahnow CA, Jelinek J, Graña X, Issa JJ.

Cell. 2018 Nov 15;175(5):1244-1258.e26. doi: 10.1016/j.cell.2018.09.051. Epub 2018 Oct 25.


FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation.

Shanmughapriya S, Tomar D, Dong Z, Slovik KJ, Nemani N, Natarajaseenivasan K, Carvalho E, Lu C, Corrigan K, Garikipati VNS, Ibetti J, Rajan S, Barrero C, Chuprun K, Kishore R, Merali S, Tian Y, Yang W, Madesh M.

Nat Commun. 2018 Aug 29;9(1):3449. doi: 10.1038/s41467-018-05856-4.


Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy.

Di Meco A, Li JG, Barrero C, Merali S, Praticò D.

Mol Psychiatry. 2019 Nov;24(11):1696-1706. doi: 10.1038/s41380-018-0062-0. Epub 2018 May 4.


The use of psychiatry-focused simulation in undergraduate nursing education: A systematic search and review.

Vandyk AD, Lalonde M, Merali S, Wright E, Bajnok I, Davies B.

Int J Ment Health Nurs. 2018 Apr;27(2):514-535. doi: 10.1111/inm.12419. Epub 2017 Dec 4. Review.


Sustainable Model for Public Health Emergency Operations Centers for Global Settings.

Balajee SA, Pasi OG, Etoundi AGM, Rzeszotarski P, Do TT, Hennessee I, Merali S, Alroy KA, Phu TD, Mounts AW.

Emerg Infect Dis. 2017 Oct;23(13). doi: 10.3201/eid2313.170435.


Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses.

Perez-Leal O, Barrero CA, Merali S.

J Biol Chem. 2017 Aug 25;292(34):14108-14121. doi: 10.1074/jbc.M116.770925. Epub 2017 Jul 6.


Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers.

Aksoy MO, Kim V, Cornwell WD, Rogers TJ, Kosmider B, Bahmed K, Barrero C, Merali S, Shetty N, Kelsen SG.

Respir Res. 2017 May 2;18(1):78. doi: 10.1186/s12931-017-0561-6.


Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.

Li JG, Barrero C, Merali S, Praticò D.

Sci Rep. 2017 Apr 6;7:46002. doi: 10.1038/srep46002.


Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology.

Li JG, Barrero C, Merali S, Praticò D.

Hum Mol Genet. 2017 May 15;26(10):1855-1862. doi: 10.1093/hmg/ddx088.


Homocysteine modulates 5-lipoxygenase expression level via DNA methylation.

Li JG, Barrero C, Gupta S, Kruger WD, Merali S, Praticò D.

Aging Cell. 2017 Apr;16(2):273-280. doi: 10.1111/acel.12550. Epub 2016 Nov 29.


Pleural effusion?-Trust your gut.

Merali S, Juma Z, Zaman Q.

Quant Imaging Med Surg. 2016 Jun;6(3):318-9. doi: 10.21037/qims.2015.03.18.


Glutamate metabolism in HIV-1 infected macrophages: Role of HIV-1 Vpr.

Datta PK, Deshmane S, Khalili K, Merali S, Gordon JC, Fecchio C, Barrero CA.

Cell Cycle. 2016 Sep;15(17):2288-98. doi: 10.1080/15384101.2016.1190054. Epub 2016 May 31.


MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.

Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, Jaña F, Huang J, Barrero C, Rabinowitz JE, Luongo TS, Schumacher SM, Rockman ME, Dietrich A, Merali S, Caplan J, Stathopulos P, Ahima RS, Cheung JY, Houser SR, Koch WJ, Patel V, Gohil VM, Elrod JW, Rajan S, Madesh M.

Cell Rep. 2016 May 24;15(8):1673-85. doi: 10.1016/j.celrep.2016.04.050. Epub 2016 May 12.


Circadian rhythm dysfunction: a novel environmental risk factor for Parkinson's disease.

Lauretti E, Di Meco A, Merali S, Praticò D.

Mol Psychiatry. 2017 Feb;22(2):280-286. doi: 10.1038/mp.2016.47. Epub 2016 Apr 5.


Chronic behavioral stress exaggerates motor deficit and neuroinflammation in the MPTP mouse model of Parkinson's disease.

Lauretti E, Di Meco A, Merali S, Praticò D.

Transl Psychiatry. 2016 Feb 9;6:e733. doi: 10.1038/tp.2016.1.


Disruption of NAD(+) binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions.

Phadke M, Krynetskaia N, Mishra A, Barrero C, Merali S, Gothe SA, Krynetskiy E.

World J Biol Chem. 2015 Nov 26;6(4):366-78. doi: 10.4331/wjbc.v6.i4.366.


The relationship between contraceptive use and maternal and infant health outcomes in Tajikistan.

Merali S.

Contraception. 2016 Mar;93(3):216-21. doi: 10.1016/j.contraception.2015.11.009. Epub 2015 Nov 24.


Characterising community exercise programmes delivered by fitness instructors for people with neurological conditions: a scoping review.

Merali S, Cameron JI, Barclay R, Salbach NM.

Health Soc Care Community. 2016 Nov;24(6):e101-e116. doi: 10.1111/hsc.12282. Epub 2015 Oct 7. Review.


Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men.

Boden G, Homko C, Barrero CA, Stein TP, Chen X, Cheung P, Fecchio C, Koller S, Merali S.

Sci Transl Med. 2015 Sep 9;7(304):304re7. doi: 10.1126/scitranslmed.aac4765.


SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells.

Obakan P, Barrero C, Coker-Gurkan A, Arisan ED, Merali S, Palavan-Unsal N.

PLoS One. 2015 Sep 9;10(9):e0135788. doi: 10.1371/journal.pone.0135788. eCollection 2015.


Changes in protein expression in two cholangiocarcinoma cell lines undergoing formation of multicellular tumor spheroids in vitro.

Mischiati C, Ura B, Roncoroni L, Elli L, Cervellati C, Squerzanti M, Conte D, Doneda L, Polverino de Laureto P, de Franceschi G, Calza R, Barrero CA, Merali S, Ferrari C, Bergamini CM, Agostinelli E.

PLoS One. 2015 Mar 10;10(3):e0118906. doi: 10.1371/journal.pone.0118906. eCollection 2015.


A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.

Chen SJ, Hoffman NE, Shanmughapriya S, Bao L, Keefer K, Conrad K, Merali S, Takahashi Y, Abraham T, Hirschler-Laszkiewicz I, Wang J, Zhang XQ, Song J, Barrero C, Shi Y, Kawasawa YI, Bayerl M, Sun T, Barbour M, Wang HG, Madesh M, Cheung JY, Miller BA.

J Biol Chem. 2014 Dec 26;289(52):36284-302. doi: 10.1074/jbc.M114.620922. Epub 2014 Nov 12.


Sildenafil for the treatment of pulmonary hypertension in children.

Beghetti M, Wacker Bou Puigdefabregas J, Merali S.

Expert Rev Cardiovasc Ther. 2014 Oct;12(10):1157-84. doi: 10.1586/14779072.2014.958077. Epub 2014 Sep 16. Review.


Response to comment on Boden et al. Insulin regulates the unfolded protein response in human adipose tissue. Diabetes 2014;63:912-922.

Boden G, Cheung P, Salehi S, Homko C, Loveland-Jones C, Jayarajan S, Stein TP, Barrero CA, Merali S, Williams KJ, Liu ML.

Diabetes. 2014 Apr;63(4):e2. doi: 10.2337/db13-1906. No abstract available.


Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles.

Li JG, Chu J, Barrero C, Merali S, Praticò D.

Ann Neurol. 2014 Jun;75(6):851-63. doi: 10.1002/ana.24145. Epub 2014 May 28.


TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria.

Miller BA, Hoffman NE, Merali S, Zhang XQ, Wang J, Rajan S, Shanmughapriya S, Gao E, Barrero CA, Mallilankaraman K, Song J, Gu T, Hirschler-Laszkiewicz I, Koch WJ, Feldman AM, Madesh M, Cheung JY.

J Biol Chem. 2014 Mar 14;289(11):7615-29. doi: 10.1074/jbc.M113.533851. Epub 2014 Feb 3.


Polyamines: Predictive Biomarker for HIV-Associated Neurocognitive Disorders.

Merali S, Barrero CA, Sacktor NC, Haughey NJ, Datta PK, Langford D, Khalili K.

J AIDS Clin Res. 2014;5(6):1000312.


Insulin regulates the unfolded protein response in human adipose tissue.

Boden G, Cheung P, Salehi S, Homko C, Loveland-Jones C, Jayarajan S, Stein TP, Williams KJ, Liu ML, Barrero CA, Merali S.

Diabetes. 2014 Mar;63(3):912-22. doi: 10.2337/db13-0906. Epub 2013 Oct 15.


Analysis of the plasma proteome in COPD: Novel low abundance proteins reflect the severity of lung remodeling.

Merali S, Barrero CA, Bowler RP, Chen DE, Criner G, Braverman A, Litwin S, Yeung A, Kelsen SG.

COPD. 2014 Apr;11(2):177-89. doi: 10.3109/15412555.2013.831063. Epub 2013 Oct 10.


Cryptosporidium parvum induces an endoplasmic stress response in the intestinal adenocarcinoma HCT-8 cell line.

Morada M, Pendyala L, Wu G, Merali S, Yarlett N.

J Biol Chem. 2013 Oct 18;288(42):30356-64. doi: 10.1074/jbc.M113.459735. Epub 2013 Aug 28.


Histone 3.3 participates in a self-sustaining cascade of apoptosis that contributes to the progression of chronic obstructive pulmonary disease.

Barrero CA, Perez-Leal O, Aksoy M, Moncada C, Ji R, Lopez Y, Mallilankaraman K, Madesh M, Criner GJ, Kelsen SG, Merali S.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):673-83. doi: 10.1164/rccm.201302-0342OC.


Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis.

Liu C, Perez-Leal O, Barrero C, Zahedi K, Soleimani M, Porter C, Merali S.

Amino Acids. 2014 Mar;46(3):701-15. doi: 10.1007/s00726-013-1548-3. Epub 2013 Jul 24.


HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.

Barrero CA, Datta PK, Sen S, Deshmane S, Amini S, Khalili K, Merali S.

PLoS One. 2013 Jul 12;8(7):e68376. doi: 10.1371/journal.pone.0068376. Print 2013.


Translational control of Nrf2 within the open reading frame.

Perez-Leal O, Barrero CA, Merali S.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):134-9. doi: 10.1016/j.bbrc.2013.06.052. Epub 2013 Jun 24.


A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase.

Perez-Leal O, Abou-Gharbia M, Gordon J, Childers WE, Merali S.

Curr Pharm Des. 2014;20(2):245-52.


Personalizing biomarker strategies in heart failure with galectin-3.

Sherwi N, Merali S, Wong K.

Future Cardiol. 2012 Nov;8(6):885-94. doi: 10.2217/fca.12.65. Review.


Identification of STAT2 serine 287 as a novel regulatory phosphorylation site in type I interferon-induced cellular responses.

Steen HC, Nogusa S, Thapa RJ, Basagoudanavar SH, Gill AL, Merali S, Barrero CA, Balachandran S, Gamero AM.

J Biol Chem. 2013 Jan 4;288(1):747-58. doi: 10.1074/jbc.M112.402529. Epub 2012 Nov 8.


Assessment of two immunodepletion methods: off-target effects and variations in immunodepletion efficiency may confound plasma proteomics.

Patel BB, Barrero CA, Braverman A, Kim PD, Jones KA, Chen DE, Bowler RP, Merali S, Kelsen SG, Yeung AT.

J Proteome Res. 2012 Dec 7;11(12):5947-58. doi: 10.1021/pr300686k. Epub 2012 Oct 29.


Prevention of Doxorubicin cardiopathic changes by a benzyl styryl sulfone in mice.

Lu M, Merali S, Gordon R, Jiang J, Li Y, Mandeli J, Duan X, Fallon J, Holland JF.

Genes Cancer. 2011 Oct;2(10):985-92. doi: 10.1177/1947601911436199.


Polyamine-regulated translation of spermidine/spermine-N1-acetyltransferase.

Perez-Leal O, Barrero CA, Clarkson AB, Casero RA Jr, Merali S.

Mol Cell Biol. 2012 Apr;32(8):1453-67. doi: 10.1128/MCB.06444-11. Epub 2012 Feb 21.


Regulation of polyamine metabolism by translational control.

Perez-Leal O, Merali S.

Amino Acids. 2012 Feb;42(2-3):611-7. doi: 10.1007/s00726-011-1036-6. Epub 2011 Aug 3. Review.


Pneumocystis S-adenosylmethionine transport: a potential drug target.

Perez-Leal O, Moncada C, Clarkson AB, Merali S.

Am J Respir Cell Mol Biol. 2011 Dec;45(6):1142-6. doi: 10.1165/rcmb.2011-0009OC. Epub 2011 Jun 3.


Pneumocystis pneumonia and S-adenosylmethionine plasma levels.

Skelly M, Merali S, Clarkson AB.

J Infect. 2011 Jun;62(6):490-2; author reply 493-5. doi: 10.1016/j.jinf.2011.04.012. Epub 2011 May 1. No abstract available.


Infusion of glucose and lipids at physiological rates causes acute endoplasmic reticulum stress in rat liver.

Boden G, Song W, Duan X, Cheung P, Kresge K, Barrero C, Merali S.

Obesity (Silver Spring). 2011 Jul;19(7):1366-73. doi: 10.1038/oby.2011.71. Epub 2011 Apr 7.

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