Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 64


Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics.

Dudka D, Castrogiovanni C, Liaudet N, Vassal H, Meraldi P.

Curr Biol. 2019 Nov 4;29(21):3563-3578.e6. doi: 10.1016/j.cub.2019.08.061. Epub 2019 Oct 24.


Identification of a Synergistic Multi-Drug Combination Active in Cancer Cells via the Prevention of Spindle Pole Clustering.

Weiss A, Le Roux-Bourdieu M, Zoetemelk M, Ramzy GM, Rausch M, Harry D, Miljkovic-Licina M, Falamaki K, Wehrle-Haller B, Meraldi P, Nowak-Sliwinska P.

Cancers (Basel). 2019 Oct 22;11(10). pii: E1612. doi: 10.3390/cancers11101612.


Cell polarity-dependent centrosome separation in the C. elegans embryo.

Bondaz A, Cirillo L, Meraldi P, Gotta M.

J Cell Biol. 2019 Dec 2;218(12):4112-4126. doi: 10.1083/jcb.201902109. Epub 2019 Oct 23.


Mild replication stress causes chromosome mis-segregation via premature centriole disengagement.

Wilhelm T, Olziersky AM, Harry D, De Sousa F, Vassal H, Eskat A, Meraldi P.

Nat Commun. 2019 Aug 8;10(1):3585. doi: 10.1038/s41467-019-11584-0.


Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expression.

Berndsen RH, Castrogiovanni C, Weiss A, Rausch M, Dallinga MG, Miljkovic-Licina M, Klaassen I, Meraldi P, van Beijnum JR, Nowak-Sliwinska P.

Br J Cancer. 2019 Jul;121(2):139-149. doi: 10.1038/s41416-019-0498-2. Epub 2019 Jun 25.


Bub1-the zombie protein that CRISPR cannot kill.

Meraldi P.

EMBO J. 2019 Apr 1;38(7). pii: e101912. doi: 10.15252/embj.2019101912. Epub 2019 Mar 8. No abstract available.


Mitotic live-cell imaging at different timescales.

Olziersky AM, Smith CA, Burroughs N, McAinsh AD, Meraldi P.

Methods Cell Biol. 2018;145:1-27. doi: 10.1016/bs.mcb.2018.03.009.


Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments.

Dudka D, Noatynska A, Smith CA, Liaudet N, McAinsh AD, Meraldi P.

Nat Commun. 2018 May 23;9(1):2042. doi: 10.1038/s41467-018-04427-x.


p37/UBXN2B regulates spindle orientation by limiting cortical NuMA recruitment via PP1/Repo-Man.

Lee BH, Schwager F, Meraldi P, Gotta M.

J Cell Biol. 2018 Feb 5;217(2):483-493. doi: 10.1083/jcb.201707050. Epub 2017 Dec 8.


Location of Mutation in BRCA2 Gene and Survival in Patients with Ovarian Cancer.

Labidi-Galy SI, Olivier T, Rodrigues M, Ferraioli D, Derbel O, Bodmer A, Petignat P, Rak B, Chopin N, Tredan O, Heudel PE, Stuckelberger S, Meeus P, Meraldi P, Viassolo V, Ayme A, Chappuis PO, Stern MH, Houdayer C, Stoppa-Lyonnet D, Buisson A, Golmard L, Bonadona V, Ray-Coquard I.

Clin Cancer Res. 2018 Jan 15;24(2):326-333. doi: 10.1158/1078-0432.CCR-17-2136. Epub 2017 Oct 30.


Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.

Gulluni F, Martini M, De Santis MC, Campa CC, Ghigo A, Margaria JP, Ciraolo E, Franco I, Ala U, Annaratone L, Disalvatore D, Bertalot G, Viale G, Noatynska A, Compagno M, Sigismund S, Montemurro F, Thelen M, Fan F, Meraldi P, Marchiò C, Pece S, Sapino A, Chiarle R, Di Fiore PP, Hirsch E.

Cancer Cell. 2017 Oct 9;32(4):444-459.e7. doi: 10.1016/j.ccell.2017.09.002.


The Elephant in the Room: The Role of Microtubules in Cancer.

Cirillo L, Gotta M, Meraldi P.

Adv Exp Med Biol. 2017;1002:93-124. doi: 10.1007/978-3-319-57127-0_5. Review.


Symmetry Does not Come for Free: Cellular Mechanisms to Achieve a Symmetric Cell Division.

Dudka D, Meraldi P.

Results Probl Cell Differ. 2017;61:301-321. doi: 10.1007/978-3-319-53150-2_14. Review.


Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity.

Berndsen RH, Weiss A, Abdul UK, Wong TJ, Meraldi P, Griffioen AW, Dyson PJ, Nowak-Sliwinska P.

Sci Rep. 2017 Feb 22;7:43005. doi: 10.1038/srep43005.


The Ska complex promotes Aurora B activity to ensure chromosome biorientation.

Redli PM, Gasic I, Meraldi P, Nigg EA, Santamaria A.

J Cell Biol. 2016 Oct 10;215(1):77-93. Epub 2016 Oct 3.


Two Ways to Get Mad at Kinetochores.

Meraldi P.

Dev Cell. 2015 Dec 7;35(5):535-536. doi: 10.1016/j.devcel.2015.11.021.


Centrosomes in spindle organization and chromosome segregation: a mechanistic view.

Meraldi P.

Chromosome Res. 2016 Jan;24(1):19-34. doi: 10.1007/s10577-015-9508-2. Review.


Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregation.

Gasic I, Nerurkar P, Meraldi P.

Elife. 2015 Aug 19;4. doi: 10.7554/eLife.07909.


The equatorial position of the metaphase plate ensures symmetric cell divisions.

Tan CH, Gasic I, Huber-Reggi SP, Dudka D, Barisic M, Maiato H, Meraldi P.

Elife. 2015 Jul 18;4. doi: 10.7554/eLife.05124.


CRL4(RBBP7) is required for efficient CENP-A deposition at centromeres.

Mouysset J, Gilberto S, Meier MG, Lampert F, Belwal M, Meraldi P, Peter M.

J Cell Sci. 2015 May 1;128(9):1732-45. doi: 10.1242/jcs.162305. Epub 2015 Mar 20.


TRAIP is a regulator of the spindle assembly checkpoint.

Chapard C, Meraldi P, Gleich T, Bachmann D, Hohl D, Huber M.

J Cell Sci. 2014 Dec 15;127(Pt 24):5149-56. doi: 10.1242/jcs.152579. Epub 2014 Oct 21.


Modulation of the chromatin phosphoproteome by the Haspin protein kinase.

Maiolica A, de Medina-Redondo M, Schoof EM, Chaikuad A, Villa F, Gatti M, Jeganathan S, Lou HJ, Novy K, Hauri S, Toprak UH, Herzog F, Meraldi P, Penengo L, Turk BE, Knapp S, Linding R, Aebersold R.

Mol Cell Proteomics. 2014 Jul;13(7):1724-40. doi: 10.1074/mcp.M113.034819. Epub 2014 Apr 14.


SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown.

Turgay Y, Champion L, Balazs C, Held M, Toso A, Gerlich DW, Meraldi P, Kutay U.

J Cell Biol. 2014 Mar 31;204(7):1099-109. doi: 10.1083/jcb.201310116. Epub 2014 Mar 24.


Nonautonomous movement of chromosomes in mitosis.

Vladimirou E, Mchedlishvili N, Gasic I, Armond JW, Samora CP, Meraldi P, McAinsh AD.

Dev Cell. 2013 Oct 14;27(1):60-71. doi: 10.1016/j.devcel.2013.08.004.


Effect of Cell Shape and Dimensionality on Spindle Orientation and Mitotic Timing.

Charnley M, Anderegg F, Holtackers R, Textor M, Meraldi P.

PLoS One. 2013 Jun 18;8(6):e66918. doi: 10.1371/journal.pone.0066918. Print 2013.


The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A.

Kress E, Schwager F, Holtackers R, Seiler J, Prodon F, Zanin E, Eiteneuer A, Toya M, Sugimoto A, Meyer H, Meraldi P, Gotta M.

J Cell Biol. 2013 May 13;201(4):559-75. doi: 10.1083/jcb.201209107. Epub 2013 May 6.


Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.

Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW.

Chromosome Res. 2013 Apr;21(2):101-6. doi: 10.1007/s10577-013-9347-y. Epub 2013 Apr 12.


Mitotic spindle (DIS)orientation and DISease: cause or consequence?

Noatynska A, Gotta M, Meraldi P.

J Cell Biol. 2012 Dec 24;199(7):1025-35. doi: 10.1083/jcb.201209015. Review.


Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.

Eskat A, Deng W, Hofmeister A, Rudolphi S, Emmerth S, Hellwig D, Ulbricht T, Döring V, Bancroft JM, McAinsh AD, Cardoso MC, Meraldi P, Hoischen C, Leonhardt H, Diekmann S.

PLoS One. 2012;7(9):e44717. doi: 10.1371/journal.pone.0044717. Epub 2012 Sep 18.


Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis.

Wandke C, Barisic M, Sigl R, Rauch V, Wolf F, Amaro AC, Tan CH, Pereira AJ, Kutay U, Maiato H, Meraldi P, Geley S.

J Cell Biol. 2012 Sep 3;198(5):847-63. doi: 10.1083/jcb.201110060.


Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation.

McHedlishvili N, Wieser S, Holtackers R, Mouysset J, Belwal M, Amaro AC, Meraldi P.

J Cell Sci. 2012 Feb 15;125(Pt 4):906-18. doi: 10.1242/jcs.091967. Epub 2012 Mar 7.


CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment.

Logarinho E, Maffini S, Barisic M, Marques A, Toso A, Meraldi P, Maiato H.

Nat Cell Biol. 2012 Feb 5;14(3):295-303. doi: 10.1038/ncb2423.


Keeping kinetochores on track.

Meraldi P.

Eur J Cell Biol. 2012 Feb;91(2):103-6. doi: 10.1016/j.ejcb.2011.10.002. Epub 2011 Nov 21. Review.


Dynamics of CENP-N kinetochore binding during the cell cycle.

Hellwig D, Emmerth S, Ulbricht T, Döring V, Hoischen C, Martin R, Samora CP, McAinsh AD, Carroll CW, Straight AF, Meraldi P, Diekmann S.

J Cell Sci. 2011 Nov 15;124(Pt 22):3871-83. doi: 10.1242/jcs.088625. Epub 2011 Nov 18.


The CCAN complex: linking centromere specification to control of kinetochore-microtubule dynamics.

McAinsh AD, Meraldi P.

Semin Cell Dev Biol. 2011 Dec;22(9):946-52. doi: 10.1016/j.semcdb.2011.09.016. Epub 2011 Oct 19. Review.


p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment.

Hagan RS, Manak MS, Buch HK, Meier MG, Meraldi P, Shah JV, Sorger PK.

Mol Biol Cell. 2011 Nov;22(22):4236-46. doi: 10.1091/mbc.E11-03-0216. Epub 2011 Sep 30.


The spindle assembly checkpoint: clock or domino?

de Medina-Redondo M, Meraldi P.

Results Probl Cell Differ. 2011;53:75-91. doi: 10.1007/978-3-642-19065-0_4. Review.


Mechanisms of aneuploidy and its suppression by tumour suppressor proteins.

Thoma CR, Toso A, Meraldi P, Krek W.

Swiss Med Wkly. 2011 Mar 8;141:w13170. doi: 10.4414/smw.2011.13170. eCollection 2011. Review.


Finding the middle ground: how kinetochores power chromosome congression.

Kops GJ, Saurin AT, Meraldi P.

Cell Mol Life Sci. 2010 Jul;67(13):2145-61. doi: 10.1007/s00018-010-0321-y. Epub 2010 Mar 16. Review.


Molecular control of kinetochore-microtubule dynamics and chromosome oscillations.

Amaro AC, Samora CP, Holtackers R, Wang E, Kingston IJ, Alonso M, Lampson M, McAinsh AD, Meraldi P.

Nat Cell Biol. 2010 Apr;12(4):319-29. doi: 10.1038/ncb2033. Epub 2010 Mar 14.


Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases.

Jaqaman K, King EM, Amaro AC, Winter JR, Dorn JF, Elliott HL, McHedlishvili N, McClelland SE, Porter IM, Posch M, Toso A, Danuser G, McAinsh AD, Meraldi P, Swedlow JR.

J Cell Biol. 2010 Mar 8;188(5):665-79. doi: 10.1083/jcb.200909005.


Double-trouble in mitosis caused by von Hippel-Lindau tumor-suppressor protein inactivation.

Thoma CR, Toso A, Meraldi P, Krek W.

Cell Cycle. 2009 Nov 15;8(22):3619-20. No abstract available.


A life outside kinetochores for Bub1 kinases?

de Medina-Redondo M, Meraldi P.

Cell Cycle. 2009 Oct 15;8(20):3250-1. Epub 2009 Oct 25. No abstract available.


COMA puts Ipl1-Sli15 at the right spot.

Amaro AC, Meraldi P.

Cell Cycle. 2009 Aug 15;8(16):2487-8. No abstract available.


VHL loss causes spindle misorientation and chromosome instability.

Thoma CR, Toso A, Gutbrodt KL, Reggi SP, Frew IJ, Schraml P, Hergovich A, Moch H, Meraldi P, Krek W.

Nat Cell Biol. 2009 Aug;11(8):994-1001. doi: 10.1038/ncb1912. Epub 2009 Jul 20.


Bub1 regulates chromosome segregation in a kinetochore-independent manner.

Klebig C, Korinth D, Meraldi P.

J Cell Biol. 2009 Jun 1;185(5):841-58. doi: 10.1083/jcb.200902128.


Analysing kinetochore function in human cells: spindle checkpoint and chromosome congression.

Klebig C, Toso A, Borusu S, Meraldi P.

Methods Mol Biol. 2009;545:205-20. doi: 10.1007/978-1-60327-993-2_12.


Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly.

Toso A, Winter JR, Garrod AJ, Amaro AC, Meraldi P, McAinsh AD.

J Cell Biol. 2009 Feb 9;184(3):365-72. doi: 10.1083/jcb.200809055.


The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity.

McClelland SE, Borusu S, Amaro AC, Winter JR, Belwal M, McAinsh AD, Meraldi P.

EMBO J. 2007 Dec 12;26(24):5033-47. Epub 2007 Nov 15.


The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.

McAinsh AD, Meraldi P, Draviam VM, Toso A, Sorger PK.

EMBO J. 2006 Sep 6;25(17):4033-49. Epub 2006 Aug 24. Erratum in: EMBO J. 2009 May 6;28(9):1374.

Supplemental Content

Loading ...
Support Center