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Items: 24


Mitochondrial quality control in the cardiac system: An integrative view.

Cadete VJJ, Vasam G, Menzies KJ, Burelle Y.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov 22. pii: S0925-4439(18)30480-0. doi: 10.1016/j.bbadis.2018.11.018. [Epub ahead of print] Review.


Critical Assessment of the mdx Mouse with Ex Vivo Eccentric Contraction of the Diaphragm Muscle.

Addicks GC, Marshall P, Jasmin BJ, Renaud JM, Zhang H, Menzies KJ.

Curr Protoc Mouse Biol. 2018 Sep;8(3):e49. doi: 10.1002/cpmo.49. Epub 2018 Aug 14.


The role of mitochondria in stem cell fate and aging.

Zhang H, Menzies KJ, Auwerx J.

Development. 2018 Apr 13;145(8). pii: dev143420. doi: 10.1242/dev.143420. Review.


Repairing Mitochondrial Dysfunction in Disease.

Sorrentino V, Menzies KJ, Auwerx J.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:353-389. doi: 10.1146/annurev-pharmtox-010716-104908. Epub 2017 Sep 27.


A multiscale study of the role of dynamin in the regulation of glucose uptake.

Trouillon R, Letizia MC, Menzies KJ, Mouchiroud L, Auwerx J, Schoonjans K, Gijs MAM.

Integr Biol (Camb). 2017 Oct 16;9(10):810-819. doi: 10.1039/c7ib00015d.


NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J.

Sci Transl Med. 2016 Oct 19;8(361):361ra139.


Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease.

Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J.

J Hepatol. 2017 Jan;66(1):132-141. doi: 10.1016/j.jhep.2016.08.024. Epub 2016 Sep 20.


NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.

Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D'Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J.

Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126/science.aaf2693. Epub 2016 Apr 28.


Protein acetylation in metabolism - metabolites and cofactors.

Menzies KJ, Zhang H, Katsyuba E, Auwerx J.

Nat Rev Endocrinol. 2016 Jan;12(1):43-60. doi: 10.1038/nrendo.2015.181. Epub 2015 Oct 27. Review.


Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.

Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku CS, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J.

Hepatology. 2016 Apr;63(4):1190-204. doi: 10.1002/hep.28245. Epub 2015 Dec 16.


NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.

Cantó C, Menzies KJ, Auwerx J.

Cell Metab. 2015 Jul 7;22(1):31-53. doi: 10.1016/j.cmet.2015.05.023. Epub 2015 Jun 25. Review.


SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport.

Stein S, Oosterveer MH, Mataki C, Xu P, Lemos V, Havinga R, Dittner C, Ryu D, Menzies KJ, Wang X, Perino A, Houten SM, Melchior F, Schoonjans K.

Cell Metab. 2014 Oct 7;20(4):603-13. doi: 10.1016/j.cmet.2014.07.023. Epub 2014 Aug 28.


SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis.

Lo Sasso G, Menzies KJ, Mottis A, Piersigilli A, Perino A, Yamamoto H, Schoonjans K, Auwerx J.

PLoS One. 2014 Jul 29;9(7):e103573. doi: 10.1371/journal.pone.0103573. eCollection 2014.


Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J.

Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8.


Altered mitochondrial morphology and defective protein import reveal novel roles for Bax and/or Bak in skeletal muscle.

Zhang Y, Iqbal S, O'Leary MF, Menzies KJ, Saleem A, Ding S, Hood DA.

Am J Physiol Cell Physiol. 2013 Sep;305(5):C502-11. doi: 10.1152/ajpcell.00058.2013. Epub 2013 Jun 19.


Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis.

Menzies KJ, Singh K, Saleem A, Hood DA.

J Biol Chem. 2013 Mar 8;288(10):6968-79. doi: 10.1074/jbc.M112.431155. Epub 2013 Jan 17.


The effects of chronic muscle use and disuse on cardiolipin metabolism.

Ostojic O, O'Leary MF, Singh K, Menzies KJ, Vainshtein A, Hood DA.

J Appl Physiol (1985). 2013 Feb 15;114(4):444-52. doi: 10.1152/japplphysiol.01312.2012. Epub 2012 Dec 6.


Commentaries on viewpoint: does SIRT1 determine exercise-induced skeletal muscle mitochondrial biogenesis: differences between in vitro and in vivo experiments?

Menzies KJ, Chabi B, Hood DA, Schenk S, Philp A, Braga VA, Guimaraes DD.

J Appl Physiol (1985). 2012 Mar;112(5):929-30. doi: 10.1152/japplphysiol.00094.2012. No abstract available. Erratum in: J Appl Physiol. 2012 May;112(10):1801. Philip, Andrew [corrected to Philp, Andrew].


The role of SirT1 in muscle mitochondrial turnover.

Menzies KJ, Hood DA.

Mitochondrion. 2012 Jan;12(1):5-13. doi: 10.1016/j.mito.2011.03.001. Epub 2011 Mar 23. Review.


Mitochondrial dysfunction is associated with a pro-apoptotic cellular environment in senescent cardiac muscle.

Ljubicic V, Menzies KJ, Hood DA.

Mech Ageing Dev. 2010 Feb;131(2):79-88. doi: 10.1016/j.mad.2009.12.004. Epub 2009 Dec 29.


Relationship between Sirt1 expression and mitochondrial proteins during conditions of chronic muscle use and disuse.

Chabi B, Adhihetty PJ, O'Leary MF, Menzies KJ, Hood DA.

J Appl Physiol (1985). 2009 Dec;107(6):1730-5. doi: 10.1152/japplphysiol.91451.2008. Epub 2009 Oct 1.


Effect of thyroid hormone on mitochondrial properties and oxidative stress in cells from patients with mtDNA defects.

Menzies KJ, Robinson BH, Hood DA.

Am J Physiol Cell Physiol. 2009 Feb;296(2):C355-62. doi: 10.1152/ajpcell.00415.2007. Epub 2008 Nov 26.


Mitochondrial function and apoptotic susceptibility in aging skeletal muscle.

Chabi B, Ljubicic V, Menzies KJ, Huang JH, Saleem A, Hood DA.

Aging Cell. 2008 Jan;7(1):2-12. Epub 2007 Nov 19.


Differential susceptibility of subsarcolemmal and intermyofibrillar mitochondria to apoptotic stimuli.

Adhihetty PJ, Ljubicic V, Menzies KJ, Hood DA.

Am J Physiol Cell Physiol. 2005 Oct;289(4):C994-C1001. Epub 2005 May 18.

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