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Items: 1 to 50 of 237

1.

Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction.

Asaumi R, Menzel K, Lee W, Nunoya KI, Imawaka H, Kusuhara H, Sugiyama Y.

CPT Pharmacometrics Syst Pharmacol. 2019 Aug 16. doi: 10.1002/psp4.12457. [Epub ahead of print]

2.

Prediction of Fraction Unbound in Microsomal and Hepatocyte Incubations: A Comparison of Methods across Industry Datasets.

Winiwarter S, Chang G, Desai P, Menzel K, Faller B, Arimoto R, Keefer C, Broccatell F.

Mol Pharm. 2019 Sep 3;16(9):4077-4085. doi: 10.1021/acs.molpharmaceut.9b00525. Epub 2019 Aug 8.

PMID:
31348668
3.

Pharmacogenetic Analysis of OATP1B1, UGT1A1, and BCRP Variants in Relation to the Pharmacokinetics of Letermovir in Previously Conducted Clinical Studies.

Kobie J, Guo Z, Cho CR, Menzel K, McCrea JB, Blanchard R, Shaw PM.

J Clin Pharmacol. 2019 Sep;59(9):1236-1243. doi: 10.1002/jcph.1420. Epub 2019 Apr 25.

PMID:
31022310
4.

Pharmacokinetic Drug-Drug Interactions Between Letermovir and the Immunosuppressants Cyclosporine, Tacrolimus, Sirolimus, and Mycophenolate Mofetil.

McCrea JB, Macha S, Adedoyin A, Marshall W, Menzel K, Cho CR, Liu F, Zhao T, Levine V, Kraft WK, Yoon E, Panebianco D, Stoch SA, Iwamoto M.

J Clin Pharmacol. 2019 Oct;59(10):1331-1339. doi: 10.1002/jcph.1423. Epub 2019 Apr 16.

PMID:
30990905
5.

PBPK Modeling Strategy for Predicting Complex Drug Interactions of Letermovir as a Perpetrator in Support of Product Labeling.

Wang YH, Chen D, Hartmann G, Cho CR, Menzel K.

Clin Pharmacol Ther. 2019 Feb;105(2):515-523. doi: 10.1002/cpt.1120. Epub 2018 Sep 11.

PMID:
29901213
6.

Pharmacokinetics and Tolerability of Letermovir Coadministered With Azole Antifungals (Posaconazole or Voriconazole) in Healthy Subjects.

Marshall WL, McCrea JB, Macha S, Menzel K, Liu F, van Schanke A, de Haes JIU, Hussaini A, Jordan HR, Drexel M, Kantesaria BS, Tsai C, Cho CR, Hulskotte EGJ, Butterton JR, Iwamoto M.

J Clin Pharmacol. 2018 Jul;58(7):897-904. doi: 10.1002/jcph.1094. Epub 2018 Mar 26.

PMID:
29578577
7.

[Practicability and Efficiency of E-health Applications in Patient-Reported Outcomes: State of and Need for Research].

Graf J, Moreno B, Wallwiener M, Menzel K, Brucker SY, Simoes E.

Gesundheitswesen. 2018 Nov;80(11):953-962. doi: 10.1055/s-0044-100037. Epub 2018 Feb 27. German.

PMID:
29486499
8.

Orientia tsutsugamushi Is Highly Susceptible to the RNA Polymerase Switch Region Inhibitor Corallopyronin A In Vitro and In Vivo.

Kock F, Hauptmann M, Osterloh A, Schäberle TF, Poppert S, Frickmann H, Menzel KD, Peschel G, Pfarr K, Schiefer A, König GM, Hoerauf A, Fleischer B, Keller C.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01732-17. doi: 10.1128/AAC.01732-17. Print 2018 Apr.

9.

Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata.

Guo H, Rischer M, Sperfeld M, Weigel C, Menzel KD, Clardy J, Beemelmanns C.

Bioorg Med Chem. 2017 Nov 15;25(22):6088-6097. doi: 10.1016/j.bmc.2017.06.053. Epub 2017 Jul 1.

10.

Survival Analysis of Orbital Implants and Potential Influencing Factors: A Retrospective Long-Term Study.

Toso SM, Menzel K, Raguse JD, Nahles S.

Int J Oral Maxillofac Implants. 2017 May/Jun;32(3):642-648. doi: 10.11607/jomi.5273.

PMID:
28494045
11.

Communication skills of medical students during the OSCE: Gender-specific differences in a longitudinal trend study.

Graf J, Smolka R, Simoes E, Zipfel S, Junne F, Holderried F, Wosnik A, Doherty AM, Menzel K, Herrmann-Werner A.

BMC Med Educ. 2017 May 2;17(1):75. doi: 10.1186/s12909-017-0913-4.

12.

Blood fibrinogen levels discriminate low- and high-risk intraductal papillary mucinous neoplasms (IPMNs).

Nentwich MF, Menzel K, Reeh M, Uzunoglu FG, Ghadban T, Bachmann K, Schrader J, Bockhorn M, Izbicki JR, Perez D.

Eur J Surg Oncol. 2017 Apr;43(4):758-762. doi: 10.1016/j.ejso.2016.12.013. Epub 2017 Jan 16.

PMID:
28131667
13.

Regioselective Dichlorination of a Non-Activated Aliphatic Carbon Atom and Phenolic Bismethylation by a Multifunctional Fungal Flavoenzyme.

Chankhamjon P, Tsunematsu Y, Ishida-Ito M, Sasa Y, Meyer F, Boettger-Schmidt D, Urbansky B, Menzel KD, Scherlach K, Watanabe K, Hertweck C.

Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11955-9. doi: 10.1002/anie.201604516. Epub 2016 Aug 25.

PMID:
27559694
14.

Prediction of Metabolic Clearance for Low-Turnover Compounds Using Plated Hepatocytes with Enzyme Activity Correction.

Ma B, Eisenhandler R, Kuo Y, Rearden P, Li Y, Manley PJ, Smith S, Menzel K.

Eur J Drug Metab Pharmacokinet. 2017 Apr;42(2):319-326. doi: 10.1007/s13318-016-0336-3.

PMID:
27101423
15.

Patient-Specific Implant in Prosthetic Craniofacial Reconstruction: First Report of a Novel Technique With Far-Reaching Perspective.

Toso SM, Menzel K, Motzkus Y, Adolphs N, Hoffmeister B, Raguse JD.

J Craniofac Surg. 2015 Oct;26(7):2133-5. doi: 10.1097/SCS.0000000000002142.

PMID:
26468797
16.

Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraine.

Crowley BM, Stump CA, Nguyen DN, Potteiger CM, McWherter MA, Paone DV, Quigley AG, Bruno JG, Cui D, Culberson JC, Danziger A, Fandozzi C, Gauvreau D, Kemmerer AL, Menzel K, Moore EL, Mosser SD, Reddy V, White RB, Salvatore CA, Kane SA, Bell IM, Selnick HG, Fraley ME, Burgey CS.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4777-4781. doi: 10.1016/j.bmcl.2015.07.021. Epub 2015 Jul 14.

PMID:
26231160
17.

Anaplastology in times of facial transplantation: Still a reasonable treatment option?

Toso SM, Menzel K, Motzkus Y, Klein M, Menneking H, Raguse JD, Nahles S, Hoffmeister B, Adolphs N.

J Craniomaxillofac Surg. 2015 Sep;43(7):1049-53. doi: 10.1016/j.jcms.2015.05.005. Epub 2015 May 29.

PMID:
26105813
18.

siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compounds.

Burke RS, Somasuntharam I, Rearden P, Brown D, Deshmukh SV, DiPietro MA, DiMuzio J, Eisenhandler R, Fauty SE, Gibson C, Gindy ME, Hamilton KA, Knemeyer I, Koeplinger KA, Kwon HW, Lifsted TQ, Menzel K, Patel M, Pudvah N, Rudd DJ, Seitzer J, Strapps WR, Prueksaritanont T, Thompson CD, Hochman JH, Carr BA.

Pharm Res. 2014 Dec;31(12):3445-60. doi: 10.1007/s11095-014-1433-0. Epub 2014 Jul 1.

PMID:
24980206
19.

[FeFe]-hydrogenase models assembled into vesicular structures.

Menzel K, Apfel UP, Wolter N, Rüger R, Alpermann T, Steiniger F, Gabel D, Förster S, Weigand W, Fahr A.

J Liposome Res. 2014 Mar;24(1):59-68. doi: 10.3109/08982104.2013.833225. Epub 2013 Sep 5.

PMID:
24006843
20.

Inhibin B response to testicular toxicants hexachlorophene, ethane dimethane sulfonate, di-(n-butyl)-phthalate, nitrofurazone, DL-ethionine, 17-alpha ethinylestradiol, 2,5-hexanedione, or carbendazim following short-term dosing in male rats.

Erdos Z, Pearson K, Goedken M, Menzel K, Sistare FD, Glaab WE, Saldutti LP.

Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):41-53. doi: 10.1002/bdrb.21035. Epub 2013 Jan 24.

PMID:
23348767
21.

Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic target.

Parmentier-Batteur S, Hutson PH, Menzel K, Uslaner JM, Mattson BA, O'Brien JA, Magliaro BC, Forest T, Stump CA, Tynebor RM, Anthony NJ, Tucker TJ, Zhang XF, Gomez R, Huszar SL, Lambeng N, Fauré H, Le Poul E, Poli S, Rosahl TW, Rocher JP, Hargreaves R, Williams TM.

Neuropharmacology. 2014 Jul;82:161-73. doi: 10.1016/j.neuropharm.2012.12.003. Epub 2013 Jan 2.

PMID:
23291536
22.

Endurance training modifies exercise-induced activation of blood coagulation: RCT.

Hilberg T, Menzel K, Wehmeier UF.

Eur J Appl Physiol. 2013 Jun;113(6):1423-30. doi: 10.1007/s00421-012-2564-9. Epub 2012 Dec 13.

PMID:
23238930
23.

Harvesting fresh water and marine algae by magnetic separation: screening of separation parameters and high gradient magnetic filtration.

Cerff M, Morweiser M, Dillschneider R, Michel A, Menzel K, Posten C.

Bioresour Technol. 2012 Aug;118:289-95. doi: 10.1016/j.biortech.2012.05.020. Epub 2012 May 14.

PMID:
22705536
24.

Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors.

Klingel S, Morath I, Strietz J, Menzel K, Holstein TW, Gradl D.

Dev Biol. 2012 Aug 1;368(1):44-53. doi: 10.1016/j.ydbio.2012.05.012. Epub 2012 May 26.

25.

Chain of coupled van der Pol oscillators as model system for density waves in dusty plasmas.

Menzel KO, Arp O, Piel A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Jul;84(1 Pt 2):016405. Epub 2011 Jul 18.

PMID:
21867320
26.

Effects of dexamethasone and atorvastatin on atrial sodium current and its early tachycardia-induced electrical remodeling in rabbits.

Laszlo R, Schwiebert M, Menzel KA, Eick C, Schreiner B, Schreieck J.

Pak J Pharm Sci. 2011 Jul;24(3):383-7.

PMID:
21715273
27.

Frequency clusters and defect structures in nonlinear dust-density waves under microgravity conditions.

Menzel KO, Arp O, Piel A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Jan;83(1 Pt 2):016402. Epub 2011 Jan 18.

PMID:
21405779
28.

Novel cytochrome P450-mediated ring opening of the 1,3,4-oxadiazole in setileuton, a 5-lipoxygenase inhibitor.

Maciolek CM, Ma B, Menzel K, Laliberte S, Bateman K, Krolikowski P, Gibson CR.

Drug Metab Dispos. 2011 May;39(5):763-70. doi: 10.1124/dmd.110.037366. Epub 2011 Feb 16.

PMID:
21325431
29.

Influence of dexamethasone on atrial ion currents and their early ionic tachycardia-induced electrical remodeling in rabbits.

Laszlo R, Schwiebert M, Menzel KA, Schreiner B, Eick C, Bosch RF, Schreieck J.

Cell Physiol Biochem. 2010;26(4-5):495-502. doi: 10.1159/000322317. Epub 2010 Oct 29.

30.

Spatial frequency clustering in nonlinear dust-density waves.

Menzel KO, Arp O, Piel A.

Phys Rev Lett. 2010 Jun 11;104(23):235002. Epub 2010 Jun 7.

PMID:
20867247
31.

Blood coagulation and fibrinolysis in healthy, untrained subjects: effects of different exercise intensities controlled by individual anaerobic threshold.

Menzel K, Hilberg T.

Eur J Appl Physiol. 2011 Feb;111(2):253-60. doi: 10.1007/s00421-010-1640-2. Epub 2010 Sep 22.

PMID:
20859637
32.

Atorvastatin treatment affects atrial ion currents and their tachycardia-induced remodeling in rabbits.

Laszlo R, Menzel KA, Bentz K, Schreiner B, Kettering K, Eick C, Schreieck J.

Life Sci. 2010 Oct 9;87(15-16):507-13. doi: 10.1016/j.lfs.2010.09.010. Epub 2010 Sep 17.

PMID:
20851131
33.

Tricyclic imidazole antagonists of the Neuropeptide S Receptor.

Trotter BW, Nanda KK, Manley PJ, Uebele VN, Condra CL, Gotter AL, Menzel K, Henault M, Stocco R, Renger JJ, Hartman GD, Bilodeau MT.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4704-8. doi: 10.1016/j.bmcl.2010.04.016. Epub 2010 Apr 13.

PMID:
20615693
34.

Production and derivate composition of trisporoids in extended fermentation of Blakeslea trispora.

Schachtschabel D, Menzel KD, Krauter G, David A, Roth M, Horn U, Boland W, Wöstemeyer J, Schimek C.

Appl Microbiol Biotechnol. 2010 Sep;88(1):241-9. doi: 10.1007/s00253-010-2720-2. Epub 2010 Jul 2.

PMID:
20596706
35.

Hygrobafilomycin, a cytotoxic and antifungal macrolide bearing a unique monoalkylmaleic anhydride moiety, from Streptomyces varsoviensis.

Tchize Ndejouong Ble S, Sattler I, Maier A, Kelter G, Menzel KD, Fiebig HH, Hertweck C.

J Antibiot (Tokyo). 2010 Jul;63(7):359-63. doi: 10.1038/ja.2010.52. Epub 2010 Jun 16.

PMID:
20551984
36.

Time-dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individuals.

Möbius-Winkler S, Hilberg T, Menzel K, Golla E, Burman A, Schuler G, Adams V.

J Appl Physiol (1985). 2009 Dec;107(6):1943-50. doi: 10.1152/japplphysiol.00532.2009. Epub 2009 Oct 1.

37.

Plasticity in gilvocarcin-type C-glycoside pathways: discovery and antitumoral evaluation of polycarcin V from Streptomyces polyformus.

Li YQ, Huang XS, Ishida K, Maier A, Kelter G, Jiang Y, Peschel G, Menzel KD, Li MG, Wen ML, Xu LH, Grabley S, Fiebig HH, Jiang CL, Hertweck C, Sattler I.

Org Biomol Chem. 2008 Oct 7;6(19):3601-5. doi: 10.1039/b808633h. Epub 2008 Jul 21.

PMID:
19082162
38.

Cooperative biosynthesis of Trisporoids by the (+) and (-) mating types of the zygomycete Blakeslea trispora.

Schachtschabel D, David A, Menzel KD, Schimek C, Wöstemeyer J, Boland W.

Chembiochem. 2008 Dec 15;9(18):3004-12. doi: 10.1002/cbic.200800477.

PMID:
19035372
39.

Coagulation and fibrinolysis are in balance after moderate exercise in middle-aged participants.

Menzel K, Hilberg T.

Clin Appl Thromb Hemost. 2009 May-Jun;15(3):348-55. doi: 10.1177/1076029608326306.

PMID:
19022797
40.

Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504) isolated from the mangrove plant Aegiceras corniculatum.

Li LY, Ding Y, Groth I, Menzel KD, Peschel G, Voigt K, Deng ZW, Sattler I, Lin WH.

J Asian Nat Prod Res. 2008 Jul-Aug;10(7-8):775-80. doi: 10.1080/10286020802031106.

PMID:
18696331
41.

(GT)N dinucleotide repeat polymorphism of haem oxygenase-1 promotor region is not associated with inflammatory bowel disease risk or disease course.

Hausmann M, Paul G, Kellermeier S, Frey I, Schölmerich J, Falk W, Menzel K, Fried M, Herfarth H, Rogler G.

Clin Exp Immunol. 2008 Jul;153(1):81-5. doi: 10.1111/j.1365-2249.2008.03674.x. Epub 2008 May 5.

42.

Benzopyrenomycin, a cytotoxic bacterial polyketide metabolite with a benzo[a]pyrene-type carbocyclic ring system.

Huang X, He J, Niu X, Menzel KD, Dahse HM, Grabley S, Fiedler HP, Sattler I, Hertweck C.

Angew Chem Int Ed Engl. 2008;47(21):3995-8. doi: 10.1002/anie.200800083. No abstract available.

PMID:
18412200
43.

NAT1 genotypes do not predict response to mesalamine in patients with ulcerative colitis.

Hausmann M, Paul G, Menzel K, Brunner-Ploss R, Falk W, Schölmerich J, Herfarth H, Rogler G.

Z Gastroenterol. 2008 Mar;46(3):259-65. doi: 10.1055/s-2007-963673.

44.

Butyrolactone I derivatives from Aspergillus terreus carrying an unusual sulfate moiety.

Niu X, Dahse HM, Menzel KD, Lozach O, Walther G, Meijer L, Grabley S, Sattler I.

J Nat Prod. 2008 Apr;71(4):689-92. doi: 10.1021/np070341r. Epub 2008 Feb 14.

PMID:
18271552
45.

Exercise intensity: platelet function and platelet-leukocyte conjugate formation in untrained subjects.

Hilberg T, Menzel K, Gläser D, Zimmermann S, Gabriel HH.

Thromb Res. 2008;122(1):77-84. Epub 2007 Oct 22.

PMID:
17945332
46.

Structure, derivatization, and antitumor activity of new griseusins from Nocardiopsis sp.

He J, Roemer E, Lange C, Huang X, Maier A, Kelter G, Jiang Y, Xu LH, Menzel KD, Grabley S, Fiebig HH, Jiang CL, Sattler I.

J Med Chem. 2007 Oct 18;50(21):5168-75. Epub 2007 Sep 18.

PMID:
17877337
47.

13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells.

Altmann R, Hausmann M, Spöttl T, Gruber M, Bull AW, Menzel K, Vogl D, Herfarth H, Schölmerich J, Falk W, Rogler G.

Biochem Pharmacol. 2007 Aug 15;74(4):612-22. Epub 2007 Jun 7.

PMID:
17604003
48.

In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis.

Hausmann M, Obermeier F, Paper DH, Balan K, Dunger N, Menzel K, Falk W, Schoelmerich J, Herfarth H, Rogler G.

Clin Exp Immunol. 2007 May;148(2):373-81.

49.

Arthroscopic stabilization in patients with an inverted pear glenoid: results in patients with bone loss of the anterior glenoid.

Mologne TS, Provencher MT, Menzel KA, Vachon TA, Dewing CB.

Am J Sports Med. 2007 Aug;35(8):1276-83.

PMID:
17387219
50.

Usefulness of severity-of-illness scores based on admission data only in nosocomial infection surveillance systems.

Gastmeier P, Menzel K, Sohr D, Rüden H.

Infect Control Hosp Epidemiol. 2007 Apr;28(4):453-8. Epub 2007 Mar 9.

PMID:
17385152

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