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Items: 14


PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.

Mense SM, Barrows D, Hodakoski C, Steinbach N, Schoenfeld D, Su W, Hopkins BD, Su T, Fine B, Hibshoosh H, Parsons R.

Sci Signal. 2015 Mar 31;8(370):ra32. doi: 10.1126/scisignal.2005840.


PTEN function: the long and the short of it.

Hopkins BD, Hodakoski C, Barrows D, Mense SM, Parsons RE.

Trends Biochem Sci. 2014 Apr;39(4):183-90. doi: 10.1016/j.tibs.2014.02.006. Epub 2014 Mar 18. Review.


Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis.

Hodakoski C, Hopkins BD, Barrows D, Mense SM, Keniry M, Anderson KE, Kern PA, Hawkins PT, Stephens LR, Parsons R.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):155-60. doi: 10.1073/pnas.1213773111. Epub 2013 Dec 23.


Dietary quercetin exacerbates the development of estrogen-induced breast tumors in female ACI rats.

Singh B, Mense SM, Bhat NK, Putty S, Guthiel WA, Remotti F, Bhat HK.

Toxicol Appl Pharmacol. 2010 Sep 1;247(2):83-90. doi: 10.1016/j.taap.2010.06.011. Epub 2010 Jun 22.


Antioxidant butylated hydroxyanisole inhibits estrogen-induced breast carcinogenesis in female ACI rats.

Singh B, Mense SM, Remotti F, Liu X, Bhat HK.

J Biochem Mol Toxicol. 2009 May-Jun;23(3):202-11. doi: 10.1002/jbt.20281.


Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats.

Mense SM, Singh B, Remotti F, Liu X, Bhat HK.

Carcinogenesis. 2009 Jul;30(7):1202-8. doi: 10.1093/carcin/bgp093. Epub 2009 Apr 30.


Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure.

Mense SM, Remotti F, Bhan A, Singh B, El-Tamer M, Hei TK, Bhat HK.

Toxicol Appl Pharmacol. 2008 Oct 1;232(1):78-85. doi: 10.1016/j.taap.2008.06.007. Epub 2008 Jul 1.


Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin.

Mense SM, Chhabra J, Bhat HK.

J Steroid Biochem Mol Biol. 2008 May;110(1-2):157-62. doi: 10.1016/j.jsbmb.2008.03.029. Epub 2008 Mar 29. Erratum in: J Steroid Biochem Mol Biol. 2014 Sep;143():266.


Phytoestrogens and breast cancer prevention: possible mechanisms of action.

Mense SM, Hei TK, Ganju RK, Bhat HK.

Environ Health Perspect. 2008 Apr;116(4):426-33. doi: 10.1289/ehp.10538. Review.


Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells.

Sengupta A, Mense SM, Lan C, Zhou M, Mauro RE, Kellerman L, Bentsman G, Volsky DJ, Louis ED, Graziano JH, Zhang L.

Neurotoxicology. 2007 May;28(3):478-89. Epub 2006 Nov 7.


The common insecticides cyfluthrin and chlorpyrifos alter the expression of a subset of genes with diverse functions in primary human astrocytes.

Mense SM, Sengupta A, Lan C, Zhou M, Bentsman G, Volsky DJ, Whyatt RM, Perera FP, Zhang L.

Toxicol Sci. 2006 Sep;93(1):125-35. Epub 2006 Jun 21.


Rqh1 blocks recombination between sister chromatids during double strand break repair, independent of its helicase activity.

Hope JC, Mense SM, Jalakas M, Mitsumoto J, Freyer GA.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5875-80. Epub 2006 Apr 4.


Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes.

Mense SM, Sengupta A, Zhou M, Lan C, Bentsman G, Volsky DJ, Zhang L.

Physiol Genomics. 2006 May 16;25(3):435-49. Epub 2006 Feb 28.


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