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Items: 32


Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.

Laurette P, Coassolo S, Davidson G, Michel I, Gambi G, Yao W, Sohier P, Li M, Mengus G, Larue L, Davidson I.

Cell Death Differ. 2019 May 7. doi: 10.1038/s41418-019-0333-6. [Epub ahead of print]


Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly.

Tawamie H, Martianov I, Wohlfahrt N, Buchert R, Mengus G, Uebe S, Janiri L, Hirsch FW, Schumacher J, Ferrazzi F, Sticht H, Reis A, Davidson I, Colombo R, Abou Jamra R.

Am J Hum Genet. 2017 Mar 2;100(3):555-561. doi: 10.1016/j.ajhg.2017.01.032.


TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.

Joshi S, Davidson G, Le Gras S, Watanabe S, Braun T, Mengus G, Davidson I.

PLoS Genet. 2017 Feb 8;13(2):e1006600. doi: 10.1371/journal.pgen.1006600. eCollection 2017 Feb.


Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.

Langer D, Martianov I, Alpern D, Rhinn M, Keime C, Dollé P, Mengus G, Davidson I.

Nat Commun. 2016 Mar 30;7:11063. doi: 10.1038/ncomms11063.


T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy.

Perez-Lloret J, Okoye IS, Guidi R, Kannan Y, Coomes SM, Czieso S, Mengus G, Davidson I, Wilson MS.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E568-76. doi: 10.1073/pnas.1522287113. Epub 2016 Jan 19.


Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

Koludrovic D, Laurette P, Strub T, Keime C, Le Coz M, Coassolo S, Mengus G, Larue L, Davidson I.

PLoS Genet. 2015 Oct 6;11(10):e1005555. doi: 10.1371/journal.pgen.1005555. eCollection 2015 Oct.


Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.

Laurette P, Strub T, Koludrovic D, Keime C, Le Gras S, Seberg H, Van Otterloo E, Imrichova H, Siddaway R, Aerts S, Cornell RA, Mengus G, Davidson I.

Elife. 2015 Mar 24;4. doi: 10.7554/eLife.06857.


TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

Alpern D, Langer D, Ballester B, Le Gras S, Romier C, Mengus G, Davidson I.

Elife. 2014 Sep 10;3:e03613. doi: 10.7554/eLife.03613.


Single-cell gene expression signatures reveal melanoma cell heterogeneity.

Ennen M, Keime C, Kobi D, Mengus G, Lipsker D, Thibault-Carpentier C, Davidson I.

Oncogene. 2015 Jun;34(25):3251-63. doi: 10.1038/onc.2014.262. Epub 2014 Aug 18.


Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation.

Benhaddou A, Keime C, Ye T, Morlon A, Michel I, Jost B, Mengus G, Davidson I.

Cell Death Differ. 2012 Feb;19(2):220-31. doi: 10.1038/cdd.2011.87. Epub 2011 Jun 24.


TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.

Gazit K, Moshonov S, Elfakess R, Sharon M, Mengus G, Davidson I, Dikstein R.

J Biol Chem. 2009 Sep 25;284(39):26286-96. doi: 10.1074/jbc.M109.011486. Epub 2009 Jul 27.


Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth.

Fadloun A, Kobi D, Delacroix L, Dembélé D, Michel I, Lardenois A, Tisserand J, Losson R, Mengus G, Davidson I.

Oncogene. 2008 Jan 17;27(4):477-89. Epub 2007 Jul 16.


The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.

Fadloun A, Kobi D, Pointud JC, Indra AK, Teletin M, Bole-Feysot C, Testoni B, Mantovani R, Metzger D, Mengus G, Davidson I.

Development. 2007 Aug;134(16):2947-58. Epub 2007 Jul 11.


TBP as a candidate gene for mental retardation in patients with subtelomeric 6q deletions.

Rooms L, Reyniers E, Scheers S, van Luijk R, Wauters J, Van Aerschot L, Callaerts-Vegh Z, D'Hooge R, Mengus G, Davidson I, Courtens W, Kooy RF.

Eur J Hum Genet. 2006 Oct;14(10):1090-6. Epub 2006 Jun 14.


New insights into TAFs as regulators of cell cycle and signaling pathways.

Davidson I, Kobi D, Fadloun A, Mengus G.

Cell Cycle. 2005 Nov;4(11):1486-90. Epub 2005 Nov 23. Review.


TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.

Mengus G, Fadloun A, Kobi D, Thibault C, Perletti L, Michel I, Davidson I.

EMBO J. 2005 Aug 3;24(15):2753-67. Epub 2005 Jul 14.


Functional integration of the histone acetyltransferase MOF into the dosage compensation complex.

Morales V, Straub T, Neumann MF, Mengus G, Akhtar A, Becker PB.

EMBO J. 2004 Jun 2;23(11):2258-68. Epub 2004 May 13.


Sequence-specific targeting of Drosophila roX genes by the MSL dosage compensation complex.

Park Y, Mengus G, Bai X, Kageyama Y, Meller VH, Becker PB, Kuroda MI.

Mol Cell. 2003 Apr;11(4):977-86.


The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.

Pointud JC, Mengus G, Brancorsini S, Monaco L, Parvinen M, Sassone-Corsi P, Davidson I.

J Cell Sci. 2003 May 1;116(Pt 9):1847-58.


Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site.

Kageyama Y, Mengus G, Gilfillan G, Kennedy HG, Stuckenholz C, Kelley RL, Becker PB, Kuroda MI.

EMBO J. 2001 May 1;20(9):2236-45.


Functional and structural analysis of the subunits of human transcription factor TFIID.

Davidson I, Romier C, Lavigne AC, Birck C, Mengus G, Poch O, Moras D.

Cold Spring Harb Symp Quant Biol. 1998;63:233-41. Review.


Synergistic transcriptional activation by TATA-binding protein and hTAFII28 requires specific amino acids of the hTAFII28 histone fold.

Lavigne AC, Gangloff YG, Carré L, Mengus G, Birck C, Poch O, Romier C, Moras D, Davidson I.

Mol Cell Biol. 1999 Jul;19(7):5050-60.


Interaction of human papillomavirus 8 regulatory proteins E2, E6 and E7 with components of the TFIID complex.

Enzenauer C, Mengus G, Lavigne A, Davidson I, Pfister H, May M.

Intervirology. 1998;41(2-3):80-90.


Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.

Birck C, Poch O, Romier C, Ruff M, Mengus G, Lavigne AC, Davidson I, Moras D.

Cell. 1998 Jul 24;94(2):239-49.


The transactivation domain of adenovirus E1A interacts with the C terminus of human TAF(II)135.

Mazzarelli JM, Mengus G, Davidson I, Ricciardi RP.

J Virol. 1997 Oct;71(10):7978-83.


Human TAF(II)28 interacts with the human T cell leukemia virus type I Tax transactivator and promotes its transcriptional activity.

Caron C, Mengus G, Dubrowskaya V, Roisin A, Davidson I, Jalinot P.

Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3662-7.


Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.

May M, Mengus G, Lavigne AC, Chambon P, Davidson I.

EMBO J. 1996 Jun 17;15(12):3093-104.


Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

Mengus G, May M, Jacq X, Staub A, Tora L, Chambon P, Davidson I.

EMBO J. 1995 Apr 3;14(7):1520-31.

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