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Items: 1 to 50 of 171

1.

Comparative study of the expression of cholinergic system components in the CNS of experimental autoimmune encephalomyelitis mice: Acute vs remitting phase.

Di Pinto G, Di Bari M, Martin-Alvarez R, Sperduti S, Serrano-Acedo S, Gatta V, Tata AM, Mengod G.

Eur J Neurosci. 2018 Sep;48(5):2165-2181. doi: 10.1111/ejn.14125.

PMID:
30144326
2.

Receptor visualization and the atomic bomb. A historical account of the development of the chemical neuroanatomy of receptors for neurotransmitters and drugs during the Cold War.

Palacios JM, Mengod G.

J Chem Neuroanat. 2018 Mar;88:76-112. doi: 10.1016/j.jchemneu.2017.07.007. Epub 2017 Jul 27. Review.

PMID:
28755996
3.

Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression.

Flores-Burgess A, Millón C, Gago B, Narváez M, Borroto-Escuela DO, Mengod G, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z.

Neuropharmacology. 2017 May 15;118:233-241. doi: 10.1016/j.neuropharm.2017.03.010. Epub 2017 Mar 11.

PMID:
28288814
4.

A preliminary investigation of phoshodiesterase 7 inhibitor VP3.15 as therapeutic agent for the treatment of experimental autoimmune encephalomyelitis mice.

Martín-Álvarez R, Paúl-Fernández N, Palomo V, Gil C, Martínez A, Mengod G.

J Chem Neuroanat. 2017 Mar;80:27-36. doi: 10.1016/j.jchemneu.2016.12.001. Epub 2016 Dec 19.

PMID:
28007551
5.

Visualization of 5-HT Receptors Using Radioligand-Binding Autoradiography.

Cortés R, Vilaró MT, Mengod G.

Curr Protoc Pharmacol. 2016 Dec 13;75:8.3.1-8.3.20. doi: 10.1002/cpph.17.

PMID:
27960027
6.

Phosphodiesterase-7 inhibition affects accumbal and hypothalamic thyrotropin-releasing hormone expression, feeding and anxiety behavior of rats.

Valdés-Moreno MI, Alcántara-Alonso V, Estrada-Camarena E, Mengod G, Amaya MI, Matamoros-Trejo G, de Gortari P.

Behav Brain Res. 2017 Feb 15;319:165-173. doi: 10.1016/j.bbr.2016.11.027. Epub 2016 Nov 15.

PMID:
27864049
7.

Cholinergic System and Neuroinflammation: Implication in Multiple Sclerosis.

Di Bari M, Di Pinto G, Reale M, Mengod G, Tata AM.

Cent Nerv Syst Agents Med Chem. 2017;17(2):109-115. doi: 10.2174/1871524916666160822115133. Review.

PMID:
27550615
8.

Mct8 and trh co-expression throughout the hypothalamic paraventricular nucleus is modified by dehydration-induced anorexia in rats.

Alvarez-Salas E, Mengod G, García-Luna C, Soberanes-Chávez P, Matamoros-Trejo G, de Gortari P.

Neuropeptides. 2016 Apr;56:33-40. doi: 10.1016/j.npep.2015.11.001. Epub 2015 Nov 10.

PMID:
26626087
9.

From unilateral to bilateral parkinsonism: Effects of lateralization on dyskinesias and associated molecular mechanisms.

Marin C, Bonastre M, Mengod G, Cortés R, Rodríguez-Oroz MC.

Neuropharmacology. 2015 Oct;97:365-75. doi: 10.1016/j.neuropharm.2015.06.004. Epub 2015 Jun 22.

PMID:
26113400
10.

Cartography of 5-HT1A and 5-HT2A Receptor Subtypes in Prefrontal Cortex and Its Projections.

Mengod G, Palacios JM, Cortés R.

ACS Chem Neurosci. 2015 Jul 15;6(7):1089-98. doi: 10.1021/acschemneuro.5b00023. Epub 2015 Mar 13. Review.

PMID:
25739427
11.

Early L-dopa, but not pramipexole, restores basal ganglia activity in partially 6-OHDA-lesioned rats.

Marin C, Bonastre M, Mengod G, Cortés R, Giralt A, Obeso JA, Schapira AH.

Neurobiol Dis. 2014 Apr;64:36-47. doi: 10.1016/j.nbd.2013.12.009. Epub 2013 Dec 24.

PMID:
24370700
12.

Subthalamic 6-OHDA-induced lesion attenuates levodopa-induced dyskinesias in the rat model of Parkinson's disease.

Marin C, Bonastre M, Mengod G, Cortés R, Rodríguez-Oroz MC, Obeso JA.

Exp Neurol. 2013 Dec;250:304-12. doi: 10.1016/j.expneurol.2013.10.006. Epub 2013 Oct 18.

PMID:
24140562
13.

Multiple conformations of 5-HT2A and 5-HT 2C receptors in rat brain: an autoradiographic study with [125I](±)DOI.

López-Giménez JF, Vilaró MT, Palacios JM, Mengod G.

Exp Brain Res. 2013 Oct;230(4):395-406. doi: 10.1007/s00221-013-3636-8. Epub 2013 Jul 18.

14.

Critical role for PDE4 subfamilies in the development of experimental autoimmune encephalomyelitis.

Sanabra C, Johansson EM, Mengod G.

J Chem Neuroanat. 2013 Jan;47:96-105. doi: 10.1016/j.jchemneu.2012.12.005. Epub 2012 Dec 26.

15.

Expression of α(1)-adrenergic receptors in rat prefrontal cortex: cellular co-localization with 5-HT(2A) receptors.

Santana N, Mengod G, Artigas F.

Int J Neuropsychopharmacol. 2013 Jun;16(5):1139-51. doi: 10.1017/S1461145712001083. Epub 2012 Nov 30.

16.

Identification in silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice.

Redondo M, Palomo V, Brea J, Pérez DI, Martín-Álvarez R, Pérez C, Paúl-Fernández N, Conde S, Cadavid MI, Loza MI, Mengod G, Martínez A, Gil C, Campillo NE.

ACS Chem Neurosci. 2012 Oct 17;3(10):793-803. doi: 10.1021/cn300105c. Epub 2012 Aug 8.

17.

Anxiolytic effects of ethanol are partially related to a reduced expression of adenylyl cyclase 5 but not to μ-opioid receptor activation in rat nucleus accumbens.

Morales-Mulia M, Estrada-Camarena E, Amaya MI, Mejía-Mauríes S, Sollozo-Dupont I, Mengod G, de Gortari P.

Behav Brain Res. 2012 Dec 1;235(2):189-94. doi: 10.1016/j.bbr.2012.07.036. Epub 2012 Aug 9.

18.

Comparison of cAMP-specific phosphodiesterase mRNAs distribution in mouse and rat brain.

Johansson EM, Reyes-Irisarri E, Mengod G.

Neurosci Lett. 2012 Sep 6;525(1):1-6. doi: 10.1016/j.neulet.2012.07.050. Epub 2012 Aug 3.

PMID:
22884617
19.

Sex-related differences of cAMP-specific PDE4B3 mRNA in oligodendrocytes following systemic inflammation.

Johansson EM, Sanabra C, Mengod G.

Glia. 2012 Dec;60(12):1815-25. doi: 10.1002/glia.22399. Epub 2012 Jul 28.

20.

Chronic effects of corticosterone on GIRK1-3 subunits and 5-HT1A receptor expression in rat brain and their reversal by concurrent fluoxetine treatment.

Saenz del Burgo L, Cortés R, Mengod G, Montaña M, García del Caño G, Sallés J.

Eur Neuropsychopharmacol. 2013 Mar;23(3):229-39. doi: 10.1016/j.euroneuro.2012.04.007. Epub 2012 May 15.

21.

Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds.

Redondo M, Brea J, Perez DI, Soteras I, Val C, Perez C, Morales-García JA, Alonso-Gil S, Paul-Fernandez N, Martin-Alvarez R, Cadavid MI, Loza MI, Perez-Castillo A, Mengod G, Campillo NE, Martinez A, Gil C.

J Med Chem. 2012 Apr 12;55(7):3274-84. doi: 10.1021/jm201720d. Epub 2012 Mar 16.

22.

Lipopolysaccharide administration in vivo induces differential expression of cAMP-specific phosphodiesterase 4B mRNA splice variants in the mouse brain.

Johansson EM, Sanabra C, Cortés R, Vilaró MT, Mengod G.

J Neurosci Res. 2011 Nov;89(11):1761-72. doi: 10.1002/jnr.22707. Epub 2011 Jul 11.

23.

Expression of parvalbumin and glutamic acid decarboxylase-67 after acute administration of MK-801. Implications for the NMDA hypofunction model of schizophrenia.

Romón T, Mengod G, Adell A.

Psychopharmacology (Berl). 2011 Sep;217(2):231-8. doi: 10.1007/s00213-011-2268-6. Epub 2011 Apr 5.

PMID:
21465242
24.

Activation of thalamocortical networks by the N-methyl-D-aspartate receptor antagonist phencyclidine: reversal by clozapine.

Santana N, Troyano-Rodriguez E, Mengod G, Celada P, Artigas F.

Biol Psychiatry. 2011 May 15;69(10):918-27. doi: 10.1016/j.biopsych.2010.10.030. Epub 2011 Jan 20.

PMID:
21251645
25.

Neuroanatomical distribution and neurochemical characterization of cells expressing adenylyl cyclase isoforms in mouse and rat brain.

Sanabra C, Mengod G.

J Chem Neuroanat. 2011 Jan;41(1):43-54. doi: 10.1016/j.jchemneu.2010.11.001. Epub 2010 Nov 19.

26.

D2 and D4 dopamine receptor mRNA distribution in pyramidal neurons and GABAergic subpopulations in monkey prefrontal cortex: implications for schizophrenia treatment.

de Almeida J, Mengod G.

Neuroscience. 2010 Nov 10;170(4):1133-9. doi: 10.1016/j.neuroscience.2010.08.025. Epub 2010 Aug 19.

27.

The human area postrema and other nuclei related to the emetic reflex express cAMP phosphodiesterases 4B and 4D.

Mori F, Pérez-Torres S, De Caro R, Porzionato A, Macchi V, Beleta J, Gavaldà A, Palacios JM, Mengod G.

J Chem Neuroanat. 2010 Sep;40(1):36-42. doi: 10.1016/j.jchemneu.2010.03.004. Epub 2010 Mar 27.

28.

NMDA receptors in frontal cortex and hippocampus of alcohol consumers.

Villegas E, Estruch R, Mengod G, Cortés R.

Addict Biol. 2011 Jan;16(1):163-5. doi: 10.1111/j.1369-1600.2009.00201.x.

29.

Ikaros-1 couples cell cycle arrest of late striatal precursors with neurogenesis of enkephalinergic neurons.

Martín-Ibáñez R, Crespo E, Urbán N, Sergent-Tanguy S, Herranz C, Jaumot M, Valiente M, Long JE, Pineda JR, Andreu C, Rubenstein JL, Marín O, Georgopoulos K, Mengod G, Fariñas I, Bachs O, Alberch J, Canals JM.

J Comp Neurol. 2010 Feb 1;518(3):329-51. doi: 10.1002/cne.22215.

PMID:
19950118
30.

Dopamine D1, D2 and mu-opioid receptors are co-expressed with adenylyl cyclase 5 and phosphodiesterase 7B mRNAs in striatal rat cells.

de Gortari P, Mengod G.

Brain Res. 2010 Jan 15;1310:37-45. doi: 10.1016/j.brainres.2009.11.009. Epub 2009 Nov 11.

31.

Effects of early vs. late initiation of levodopa treatment in hemiparkinsonian rats.

Marin C, Aguilar E, Mengod G, Cortés R, Obeso JA.

Eur J Neurosci. 2009 Sep;30(5):823-32. doi: 10.1111/j.1460-9568.2009.06877.x. Epub 2009 Aug 27.

PMID:
19712101
32.

Lack of CB1 receptor activity impairs serotonergic negative feedback.

Aso E, Renoir T, Mengod G, Ledent C, Hamon M, Maldonado R, Lanfumey L, Valverde O.

J Neurochem. 2009 May;109(3):935-44. doi: 10.1111/j.1471-4159.2009.06025.x. Epub 2009 Mar 3.

33.

Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers.

Brea J, Castro M, Giraldo J, López-Giménez JF, Padín JF, Quintián F, Cadavid MI, Vilaró MT, Mengod G, Berg KA, Clarke WP, Vilardaga JP, Milligan G, Loza MI.

Mol Pharmacol. 2009 Jun;75(6):1380-91. doi: 10.1124/mol.108.054395. Epub 2009 Mar 11.

PMID:
19279328
34.

NMDA antagonist and antipsychotic actions in cortico-subcortical circuits.

Kargieman L, Santana N, Mengod G, Celada P, Artigas F.

Neurotox Res. 2008 Oct;14(2-3):129-40. doi: 10.1007/BF03033805.

PMID:
19073421
35.

Distribution of 5-HT and DA receptors in primate prefrontal cortex: implications for pathophysiology and treatment.

de Almeida J, Palacios JM, Mengod G.

Prog Brain Res. 2008;172:101-15. doi: 10.1016/S0079-6123(08)00905-9. Review.

PMID:
18772029
36.
37.

Entacapone potentiates the long-duration response but does not normalize levodopa-induced molecular changes.

Marin C, Aguilar E, Mengod G, Cortés R, Rodríguez-Oroz MC, Obeso JA.

Neurobiol Dis. 2008 Dec;32(3):340-8. doi: 10.1016/j.nbd.2008.07.019. Epub 2008 Aug 5.

38.

Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain.

Saenz del Burgo L, Cortes R, Mengod G, Zarate J, Echevarria E, Salles J.

J Comp Neurol. 2008 Oct 20;510(6):581-606. doi: 10.1002/cne.21810.

39.

Quantitative analysis of the expression of dopamine D1 and D2 receptors in pyramidal and GABAergic neurons of the rat prefrontal cortex.

Santana N, Mengod G, Artigas F.

Cereb Cortex. 2009 Apr;19(4):849-60. doi: 10.1093/cercor/bhn134. Epub 2008 Aug 9.

PMID:
18689859
40.

Differential distribution of PDE4B splice variant mRNAs in rat brain and the effects of systemic administration of LPS in their expression.

Reyes-Irisarri E, Pérez-Torres S, Miró X, Martínez E, Puigdomènech P, Palacios JM, Mengod G.

Synapse. 2008 Jan;62(1):74-9.

PMID:
17960764
41.

Selective induction of cAMP phosphodiesterase PDE4B2 expression in experimental autoimmune encephalomyelitis.

Reyes-Irisarri E, Sánchez AJ, García-Merino JA, Mengod G.

J Neuropathol Exp Neurol. 2007 Oct;66(10):923-31.

PMID:
17917586
42.

Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by NMDA receptor blockade with phencyclidine.

Kargieman L, Santana N, Mengod G, Celada P, Artigas F.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14843-8. Epub 2007 Sep 4.

43.
44.

Expression of the cGMP-specific phosphodiesterases 2 and 9 in normal and Alzheimer's disease human brains.

Reyes-Irisarri E, Markerink-Van Ittersum M, Mengod G, de Vente J.

Eur J Neurosci. 2007 Jun;25(11):3332-8.

PMID:
17553001
45.

Concomitant short- and long-duration response to levodopa in the 6-OHDA-lesioned rat: a behavioural and molecular study.

Marin C, Aguilar E, Mengod G, Cortés R, Obeso JA.

Eur J Neurosci. 2007 Jan;25(1):259-69.

PMID:
17241287
46.

Species differences in the localization of soluble guanylyl cyclase subunits in monkey and rat brain.

Pifarré P, García A, Mengod G.

J Comp Neurol. 2007 Feb 10;500(5):942-57.

PMID:
17177259
47.
48.

Neuroprotection induced by the adenosine A2A antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways.

Bové J, Serrats J, Mengod G, Cortés R, Tolosa E, Marin C.

Exp Brain Res. 2005 Sep;165(3):362-74. Epub 2005 Jun 21.

PMID:
15968457
49.

Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease.

Pineda JR, Canals JM, Bosch M, Adell A, Mengod G, Artigas F, Ernfors P, Alberch J.

J Neurochem. 2005 Jun;93(5):1057-68.

50.

Neuronal expression of cAMP-specific phosphodiesterase 7B mRNA in the rat brain.

Reyes-Irisarri E, Pérez-Torres S, Mengod G.

Neuroscience. 2005;132(4):1173-85.

PMID:
15857719

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