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Items: 1 to 50 of 85

1.

The beclomethasone anti-inflammatory effect occurs in cell/mediator-dependent manner and is additively enhanced by formoterol: NFkB, p38, PKA analysis.

Cianchetti S, Cardini C, Corti A, Menegazzi M, Darra E, Ingrassia E, Pompella A, Paggiaro P.

Life Sci. 2018 Jun 15;203:27-38. doi: 10.1016/j.lfs.2018.04.015. Epub 2018 Apr 13.

PMID:
29660434
2.

Asthma and poly(ADP-ribose) polymerase inhibition: a new therapeutic approach.

Zaffini R, Gotte G, Menegazzi M.

Drug Des Devel Ther. 2018 Feb 12;12:281-293. doi: 10.2147/DDDT.S150846. eCollection 2018. Review.

3.

Phosphorylation of pyridoxal 5'-phosphate enzymes: an intriguing and neglected topic.

Rossignoli G, Phillips RS, Astegno A, Menegazzi M, Voltattorni CB, Bertoldi M.

Amino Acids. 2018 Feb;50(2):205-215. doi: 10.1007/s00726-017-2521-3. Epub 2017 Dec 4. Review.

PMID:
29204749
4.

Persistence of STAT-1 inhibition and induction of cytokine resistance in pancreatic β cells treated with St John's wort and its component hyperforin.

Novelli M, Beffy P, Gregorelli A, Porozov S, Mascia F, Vantaggiato C, Masiello P, Menegazzi M.

J Pharm Pharmacol. 2017 Oct 9. doi: 10.1111/jphp.12823. [Epub ahead of print]

PMID:
28990659
5.

St. John's wort extract and hyperforin inhibit multiple phosphorylation steps of cytokine signaling and prevent inflammatory and apoptotic gene induction in pancreatic β cells.

Novelli M, Menegazzi M, Beffy P, Porozov S, Gregorelli A, Giacopelli D, De Tata V, Masiello P.

Int J Biochem Cell Biol. 2016 Dec;81(Pt A):92-104. doi: 10.1016/j.biocel.2016.10.017. Epub 2016 Oct 22.

PMID:
27780755
6.

PARP inhibition treatment in a nonconventional experimental mouse model of chronic asthma.

Zaffini R, Di Paola R, Cuzzocrea S, Menegazzi M.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Dec;389(12):1301-1313. Epub 2016 Sep 7.

PMID:
27604227
7.

Three Arachidonoylamide Derivatives Inhibit Pro-Inflammatory Genes Expression by Modulating NF-kB and AP1 Activities.

Gregorelli A, Sgarbossa A, Khan S, Soriente A, De Rosa M, Saturnino C, Menegazzi M.

Med Chem. 2016;12(7):662-673.

PMID:
27140182
8.

Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment.

Zoico E, Darra E, Rizzatti V, Budui S, Franceschetti G, Mazzali G, Rossi AP, Fantin F, Menegazzi M, Cinti S, Zamboni M.

Oncotarget. 2016 Apr 12;7(15):20223-35. doi: 10.18632/oncotarget.7936.

9.

Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways.

Masullo M, Menegazzi M, Di Micco S, Beffy P, Bifulco G, Dal Bosco M, Novelli M, Pizza C, Masiello P, Piacente S.

J Nat Prod. 2014 Mar 28;77(3):543-9. doi: 10.1021/np400804y. Epub 2014 Jan 13.

PMID:
24417609
10.

Direct interaction of natural and synthetic catechins with signal transducer activator of transcription 1 affects both its phosphorylation and activity.

Menegazzi M, Mariotto S, Dal Bosco M, Darra E, Vaiana N, Shoji K, Safwat AA, Marechal JD, Perahia D, Suzuki H, Romeo S.

FEBS J. 2014 Feb;281(3):724-38. doi: 10.1111/febs.12618. Epub 2013 Dec 10.

11.

St. John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity.

Novelli M, Beffy P, Menegazzi M, De Tata V, Martino L, Sgarbossa A, Porozov S, Pippa A, Masini M, Marchetti P, Masiello P.

Acta Diabetol. 2014 Feb;51(1):113-21.

12.

Polymorphism -2604G>A variants in TLR4 promoter are associated with different gene expression level in peripheral blood of atherosclerotic patients.

Ferronato S, Gomez-Lira M, Menegazzi M, Diani E, Olivato S, Sartori M, Scuro A, Malerba G, Pignatti PF, Romanelli MG, Mazzucco S.

J Hum Genet. 2013 Dec;58(12):812-4. doi: 10.1038/jhg.2013.98. Epub 2013 Oct 10.

PMID:
24108365
13.

γ-Glutamyltransferase catabolism of S-nitrosoglutathione modulates IL-8 expression in cystic fibrosis bronchial epithelial cells.

Corti A, Bergamini G, Menegazzi M, Piaggi S, Bramanti E, Scataglini I, Cianchetti S, Paggiaro P, Melotti P, Pompella A.

Free Radic Biol Med. 2013 Dec;65:360-370. doi: 10.1016/j.freeradbiomed.2013.06.015. Epub 2013 Jun 29.

PMID:
23820266
14.

Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis.

Fiorini C, Menegazzi M, Padroni C, Dando I, Dalla Pozza E, Gregorelli A, Costanzo C, Palmieri M, Donadelli M.

Apoptosis. 2013 Mar;18(3):337-46. doi: 10.1007/s10495-012-0790-6.

PMID:
23238993
15.

Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors.

Sgarbossa A, Dal Bosco M, Pressi G, Cuzzocrea S, Dal Toso R, Menegazzi M.

Chem Biol Interact. 2012 Aug 30;199(2):87-95. doi: 10.1016/j.cbi.2012.06.006. Epub 2012 Jun 23.

PMID:
22735309
16.

Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine.

Dalla Pozza E, Fiorini C, Dando I, Menegazzi M, Sgarbossa A, Costanzo C, Palmieri M, Donadelli M.

Biochim Biophys Acta. 2012 Oct;1823(10):1856-63. doi: 10.1016/j.bbamcr.2012.06.007. Epub 2012 Jun 15.

17.

Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury.

Scarabelli TM, Mariotto S, Abdel-Azeim S, Shoji K, Darra E, Stephanou A, Chen-Scarabelli C, Marechal JD, Knight R, Ciampa A, Saravolatz L, de Prati AC, Yuan Z, Cavalieri E, Menegazzi M, Latchman D, Pizza C, Perahia D, Suzuki H.

FEBS Lett. 2009 Feb 4;583(3):531-41. doi: 10.1016/j.febslet.2008.12.037. Epub 2008 Dec 29.

18.

Protective effects of glycyrrhizin in a gut hypoxia (ischemia)-reoxygenation (reperfusion) model.

Di Paola R, Menegazzi M, Mazzon E, Genovese T, Crisafulli C, Dal Bosco M, Zou Z, Suzuki H, Cuzzocrea S.

Intensive Care Med. 2009 Apr;35(4):687-97. doi: 10.1007/s00134-008-1334-y. Epub 2008 Oct 25.

PMID:
18953525
19.

Doppler analysis and placental nitric oxide synthase expression during fetal growth restriction.

Giannubilo SR, Menegazzi M, Tedeschi E, Bezzeccheri V, Suzuki H, Tranquilli AL.

J Matern Fetal Neonatal Med. 2008 Sep;21(9):617-22. doi: 10.1080/14767050802214774.

PMID:
18828052
20.

Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice.

Genovese T, Menegazzi M, Mazzon E, Crisafulli C, Di Paola R, Dal Bosco M, Zou Z, Suzuki H, Cuzzocrea S.

Shock. 2009 Apr;31(4):367-75. doi: 10.1097/SHK.0b013e3181833b08.

PMID:
18665052
21.

Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice.

Menegazzi M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Dal Bosco M, Zou Z, Suzuki H, Cuzzocrea S.

Pharmacol Res. 2008 Jul;58(1):22-31. doi: 10.1016/j.phrs.2008.05.012. Epub 2008 Jun 11.

PMID:
18590825
22.

Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line.

Menegazzi M, Novelli M, Beffy P, D'Aleo V, Tedeschi E, Lupi R, Zoratti E, Marchetti P, Suzuki H, Masiello P.

Int J Biochem Cell Biol. 2008;40(8):1509-21. doi: 10.1016/j.biocel.2007.11.019. Epub 2007 Dec 8.

PMID:
18226577
23.

Transcription factor expression, RNA synthesis and NADPH-diaphorase across the rat brain and exposure to spatial novelty.

Romanelli P, Di Matteo L, Cobellis G, Varriale B, Menegazzi M, Gironi Carnevale UA, Ruocco LA, Sadile AG.

Behav Brain Res. 2007 Nov 22;184(1):91-100. Epub 2007 Jun 30.

PMID:
17706799
24.

Effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation.

Menegazzi JJ, Salcido DD, Menegazzi MT, Rittenberger JC, Suffoletto BP, Logue ES, Mader TJ.

Prehosp Emerg Care. 2007 Apr-Jun;11(2):179-85.

PMID:
17454804
25.

Green tea polyphenol extract attenuates zymosan-induced non-septic shock in mice.

Di Paola R, Mazzon E, Muià C, Crisafulli C, Genovese T, Di Bella P, Esposito E, Menegazzi M, Meli R, Suzuki H, Cuzzocrea S.

Shock. 2006 Oct;26(4):402-9.

PMID:
16980889
26.

Protective effect of Hypericum perforatum in zymosan-induced multiple organ dysfunction syndrome: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.

Di Paola R, Mazzon E, Muià C, Crisafulli C, Genovese T, Di Bella P, Esposito E, Menegazzi M, Meli R, Suzuki H, Cuzzocrea S.

Nitric Oxide. 2007 Feb;16(1):118-30. Epub 2006 Jun 15.

PMID:
16889996
27.

Early nuclear factor-kappaB activation and inducible nitric oxide synthase expression in injured spinal cord neurons correlating with a diffuse reduction of constitutive nitric oxide synthase activity.

Miscusi M, Ebner F, Ceccariglia S, Menegazzi M, Mariotto S, Berra L, Del Fa A, Gangitano C, Lauretti L, Missori P, Delfini R, Suzuki H.

J Neurosurg Spine. 2006 Jun;4(6):485-93.

PMID:
16776360
28.

Neuroprotection and enhanced recovery with hypericum perforatum extract after experimental spinal cord injury in mice.

Genovese T, Mazzon E, Menegazzi M, Di Paola R, Muià C, Crisafulli C, Bramanti P, Suzuki H, Cuzzocrea S.

Shock. 2006 Jun;25(6):608-17.

PMID:
16721269
29.

Hypericum perforatum attenuates the development of cerulein-induced acute pancreatitis in mice.

Genovese T, Mazzon E, Di Paola R, Muià C, Crisafulli C, Menegazzi M, Malleo G, Suzuki H, Cuzzocrea S.

Shock. 2006 Feb;25(2):161-7.

PMID:
16525355
30.

Epigallocatechin-3-gallate reduces allergen-induced asthma-like reaction in sensitized guinea pigs.

Bani D, Giannini L, Ciampa A, Masini E, Suzuki Y, Menegazzi M, Nistri S, Suzuki H.

J Pharmacol Exp Ther. 2006 Jun;317(3):1002-11. Epub 2006 Mar 8.

31.

Hypericum perforatum attenuates the development of carrageenan-induced lung injury in mice.

Menegazzi M, Di Paola R, Mazzon E, Muià C, Genovese T, Crisafulli C, Suzuki H, Cuzzocrea S.

Free Radic Biol Med. 2006 Mar 1;40(5):740-53. Epub 2005 Nov 10.

PMID:
16520227
32.

Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury.

Genovese T, Mazzon E, Mariotto S, Menegazzi M, Cardali S, Conti A, Suzuki H, Bramanti P, Cuzzocrea S.

J Neurosurg Spine. 2006 Feb;4(2):145-53.

PMID:
16506482
33.

Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia.

Columbano A, Ledda-Columbano GM, Pibiri M, Cossu C, Menegazzi M, Moore DD, Huang W, Tian J, Locker J.

Hepatology. 2005 Nov;42(5):1118-26.

PMID:
16231353
34.

Effects of Hypericum perforatum extract in a rat model of ischemia and reperfusion injury.

De Paola R, Muià C, Mazzon E, Genovese T, Crisafulli C, Menegazzi M, Caputi AP, Suzuki H, Cuzzocrea S.

Shock. 2005 Sep;24(3):255-63.

PMID:
16135965
35.

STAT1 as a new molecular target of anti-inflammatory treatment.

de Prati AC, Ciampa AR, Cavalieri E, Zaffini R, Darra E, Menegazzi M, Suzuki H, Mariotto S.

Curr Med Chem. 2005;12(16):1819-28. Review.

PMID:
16101503
36.

Placental expression of nitric oxide synthase during HELLP syndrome: the correlation with maternal-fetal Doppler velocimetry.

Tranquilli AL, Giannubilo SR, Tedeschi E, Bezzeccheri V, Suzuki H, Menegazzi M.

Acta Obstet Gynecol Scand. 2005 Sep;84(9):849-53.

PMID:
16097974
37.

Green tea polyphenol extract attenuates colon injury induced by experimental colitis.

Mazzon E, Muià C, Paola RD, Genovese T, Menegazzi M, De Sarro A, Suzuki H, Cuzzocrea S.

Free Radic Res. 2005 Sep;39(9):1017-25.

PMID:
16087483
38.

Green tea polyphenol extract attenuates ischemia/reperfusion injury of the gut.

Muià C, Mazzon E, Di Paola R, Genovese T, Menegazzi M, Caputi AP, Suzuki H, Cuzzocrea S.

Naunyn Schmiedebergs Arch Pharmacol. 2005 May;371(5):364-74. Epub 2005 Jul 5.

PMID:
15997392
39.

Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.

Di Paola R, Mazzon E, Muià C, Genovese T, Menegazzi M, Zaffini R, Suzuki H, Cuzzocrea S.

Respir Res. 2005 Jun 29;6:66.

40.

Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis.

Townsend PA, Scarabelli TM, Pasini E, Gitti G, Menegazzi M, Suzuki H, Knight RA, Latchman DS, Stephanou A.

FASEB J. 2004 Oct;18(13):1621-3. Epub 2004 Aug 19.

PMID:
15319365
41.

Biochemical aspects of nitric oxide.

Mariotto S, Menegazzi M, Suzuki H.

Curr Pharm Des. 2004;10(14):1627-45. Review.

PMID:
15134561
42.

The variations during the circadian cycle of liver CD1d-unrestricted NK1.1+TCR gamma/delta+ cells lead to successful ageing. Role of metallothionein/IL-6/gp130/PARP-1 interplay in very old mice.

Mocchegiani E, Giacconi R, Cipriano C, Gasparini N, Bernardini G, Malavolta M, Menegazzi M, Cavalieri E, Muzzioli M, Ciampa AR, Suzuki H.

Exp Gerontol. 2004 May;39(5):775-88.

PMID:
15130672
43.

Green tea inhibits human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha activation.

Tedeschi E, Menegazzi M, Yao Y, Suzuki H, Förstermann U, Kleinert H.

Mol Pharmacol. 2004 Jan;65(1):111-20.

44.
45.

Antiinflammatory action of EGCG, the main component of green tea, through STAT-1 inhibition.

Tedeschi E, Suzuki H, Menegazzi M.

Ann N Y Acad Sci. 2002 Nov;973:435-7. No abstract available.

PMID:
12485906
46.

Collagen I and III mRNA gene expression and cell growth potential of skin fibroblasts in patients with essential hypertension.

Delva P, Lechi A, Pastori C, Degan M, Sheiban I, Montesi G, Pea M, Meneguzzi A, Menegazzi M.

J Hypertens. 2002 Jul;20(7):1393-9.

PMID:
12131536
47.

NF-kappaB and ERK cooperate to stimulate DNA synthesis by inducing ornithine decarboxylase and nitric oxide synthase in cardiomyocytes treated with TNF and LPS.

Tantini B, Pignatti C, Fattori M, Flamigni F, Stefanelli C, Giordano E, Menegazzi M, Clô C, Caldarera CM.

FEBS Lett. 2002 Feb 13;512(1-3):75-9.

48.

Anti-interferon gamma action of epigallocatechin-3-gallate mediated by specific inhibition of STAT1 activation.

Menegazzi M, Tedeschi E, Dussin D, De Prati AC, Cavalieri E, Mariotto S, Suzuki H.

FASEB J. 2001 May;15(7):1309-11. No abstract available.

PMID:
11344123
49.

The stimulation of inducible nitric-oxide synthase by the prion protein fragment 106--126 in human microglia is tumor necrosis factor-alpha-dependent and involves p38 mitogen-activated protein kinase.

Fabrizi C, Silei V, Menegazzi M, Salmona M, Bugiani O, Tagliavini F, Suzuki H, Lauro GM.

J Biol Chem. 2001 Jul 13;276(28):25692-6. Epub 2001 Apr 20.

50.

Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3).

Pibiri M, Ledda-Columbano GM, Cossu C, Simbula G, Menegazzi M, Shinozuka H, Columbano A.

FASEB J. 2001 Apr;15(6):1006-13.

PMID:
11292661

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