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Items: 1 to 50 of 161

1.

XPD/ERCC2 mutations interfere in cellular responses to oxidative stress.

Lerner LK, Moreno NC, Rocha CRR, Munford V, Santos V, Soltys DT, Garcia CCM, Sarasin A, Menck CFM.

Mutagenesis. 2019 Jul 26. pii: gez020. doi: 10.1093/mutage/gez020. [Epub ahead of print]

PMID:
31348825
2.

ATR mediates cisplatin resistance in 3D-cultured breast cancer cells via translesion DNA synthesis modulation.

Gomes LR, Rocha CRR, Martins DJ, Fiore APZP, Kinker GS, Bruni-Cardoso A, Menck CFM.

Cell Death Dis. 2019 Jun 12;10(6):459. doi: 10.1038/s41419-019-1689-8.

3.

NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide.

Melo-Hanchuk TD, Slepicka PF, Pelegrini AL, Menck CFM, Kobarg J.

J Cell Biochem. 2019 May 15. doi: 10.1002/jcb.28943. [Epub ahead of print]

PMID:
31090963
4.

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum.

Sarasin A, Quentin S, Droin N, Sahbatou M, Saada V, Auger N, Boursin Y, Dessen P, Raimbault A, Asnafi V, Schmutz JL, Taïeb A, Menck CFM, Rosselli F, La Rochelle LD, Robert C, Sicre de Fontbrune F, Sébert M, Leblanc T, Kannouche P, De Botton S, Solary E, Soulier J.

Blood. 2019 Jun 20;133(25):2718-2724. doi: 10.1182/blood-2019-01-895698. Epub 2019 Mar 26. No abstract available.

5.

Genetic and behavioral characterization of a Kmt2d mouse mutant, a new model for Kabuki Syndrome.

Yamamoto PK, de Souza TA, Antiorio ATFB, Zanatto DA, Garcia-Gomes MSA, Alexandre-Ribeiro SR, Oliveira NS, Menck CFM, Bernardi MM, Massironi SMG, Mori CMC.

Genes Brain Behav. 2019 Mar 20:e12568. doi: 10.1111/gbb.12568. [Epub ahead of print]

PMID:
30891914
6.

Mutation in NADPH oxidase 3 (NOX3) impairs SHH signaling and increases cerebellar neural stem/progenitor cell proliferation.

Mazzonetto PC, Ariza CB, Ocanha SG, de Souza TA, Ko GM, Menck CFM, Massironi SMG, Porcionatto MA.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1502-1515. doi: 10.1016/j.bbadis.2019.02.022. Epub 2019 Mar 8.

PMID:
30853403
7.

The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells.

Moreno NC, Garcia CCM, Munford V, Rocha CRR, Pelegrini AL, Corradi C, Sarasin A, Menck CFM.

Free Radic Biol Med. 2019 Feb 1;131:432-442. doi: 10.1016/j.freeradbiomed.2018.12.012. Epub 2018 Dec 13.

PMID:
30553972
8.

Filling gaps in translesion DNA synthesis in human cells.

Quinet A, Lerner LK, Martins DJ, Menck CFM.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Dec;836(Pt B):127-142. doi: 10.1016/j.mrgentox.2018.02.004. Epub 2018 Feb 23. Review.

PMID:
30442338
9.

ATR/Chk1 Pathway is Activated by Oxidative Stress in Response to UVA Light in Human Xeroderma Pigmentosum Variant Cells.

Moreno NC, Garcia CCM, Rocha CRR, Munford V, Menck CFM.

Photochem Photobiol. 2019 Jan;95(1):345-354. doi: 10.1111/php.13041. Epub 2018 Nov 23.

PMID:
30362123
10.

DNA repair pathways and cisplatin resistance: an intimate relationship.

Rocha CRR, Silva MM, Quinet A, Cabral-Neto JB, Menck CFM.

Clinics (Sao Paulo). 2018 Sep 6;73(suppl 1):e478s. doi: 10.6061/clinics/2018/e478s. Review.

11.

DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress.

Fortunato RS, Gomes LR, Munford V, Pessoa CF, Quinet A, Hecht F, Kajitani GS, Milito CB, Carvalho DP, Menck CFM.

Oxid Med Cell Longev. 2018 Apr 19;2018:3570526. doi: 10.1155/2018/3570526. eCollection 2018.

12.

Genoprotective Effect of Phyllanthus orbicularis Extract Against UVA, UVB, and Solar Radiation.

Tamayo MV, Schuch AP, Yagura T, Gil LB, Menck CFM, Sánchez-Lamar A.

Photochem Photobiol. 2018 Sep;94(5):1026-1031. doi: 10.1111/php.12939. Epub 2018 Jul 4.

PMID:
29768722
13.

Horizontal Gene Transfer Building Prokaryote Genomes: Genes Related to Exchange Between Cell and Environment are Frequently Transferred.

Paquola ACM, Asif H, Pereira CAB, Feltes BC, Bonatto D, Lima WC, Menck CFM.

J Mol Evol. 2018 Apr;86(3-4):190-203. doi: 10.1007/s00239-018-9836-x. Epub 2018 Mar 19.

PMID:
29556740
14.

Autophagy Roles in the Modulation of DNA Repair Pathways.

Gomes LR, Menck CFM, Leandro GS.

Int J Mol Sci. 2017 Nov 7;18(11). pii: E2351. doi: 10.3390/ijms18112351. Review.

15.

Biomass burning in the Amazon region causes DNA damage and cell death in human lung cells.

de Oliveira Alves N, Vessoni AT, Quinet A, Fortunato RS, Kajitani GS, Peixoto MS, Hacon SS, Artaxo P, Saldiva P, Menck CFM, Batistuzzo de Medeiros SR.

Sci Rep. 2017 Sep 7;7(1):10937. doi: 10.1038/s41598-017-11024-3.

16.

LMNB1 mutation causes cerebellar involvement and a genome instability defect.

Pedroso JL, Munford V, Bastos AU, Castro LP, Marussi VHR, Silva GS, Arita JH, Menck CFM, Barsottini OG.

J Neurol Sci. 2017 Aug 15;379:249-252. doi: 10.1016/j.jns.2017.06.027. Epub 2017 Jun 16. No abstract available.

PMID:
28716252
17.

Molecular characterization of Caulobacter crescentus mutator strains.

Martins-Pinheiro M, Oliveira AR, Valencia AO, Fernandez-Silva FS, Silva LG, Lopes-Kulishev CO, Italiani VCS, Marques MV, Menck CF, Galhardo RS.

Gene. 2017 Aug 30;626:251-257. doi: 10.1016/j.gene.2017.05.038. Epub 2017 May 19.

PMID:
28533123
18.

Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.

Gomes LR, Menck CFM, Cuervo AM.

Autophagy. 2017 May 4;13(5):928-940. doi: 10.1080/15548627.2017.1293767. Epub 2017 Mar 2.

19.

Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.

Muñoz MJ, Nieto Moreno N, Giono LE, Cambindo Botto AE, Dujardin G, Bastianello G, Lavore S, Torres-Méndez A, Menck CFM, Blencowe BJ, Irimia M, Foiani M, Kornblihtt AR.

Cell Rep. 2017 Mar 21;18(12):2868-2879. doi: 10.1016/j.celrep.2017.02.066.

20.

The third of a series of articles for the 60th anniversary of the Brazilian Society of Genetics.

Salzano FM, Santos FR, Hartfelder K, Menck CFM.

Genet Mol Biol. 2017 Jan-Mar;40(1):I. doi: 10.1590/1678-4685-GMB-2017-00010001. No abstract available.

21.

Direct participation of DNA in the formation of singlet oxygen and base damage under UVA irradiation.

Yagura T, Schuch AP, Garcia CCM, Rocha CRR, Moreno NC, Angeli JPF, Mendes D, Severino D, Bianchini Sanchez A, Di Mascio P, de Medeiros MHG, Menck CFM.

Free Radic Biol Med. 2017 Jul;108:86-93. doi: 10.1016/j.freeradbiomed.2017.03.018. Epub 2017 Mar 18.

PMID:
28323132
22.

Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells.

Lerner LK, Francisco G, Soltys DT, Rocha CR, Quinet A, Vessoni AT, Castro LP, David TI, Bustos SO, Strauss BE, Gottifredi V, Stary A, Sarasin A, Chammas R, Menck CF.

Nucleic Acids Res. 2017 Feb 17;45(3):1270-1280. doi: 10.1093/nar/gkw1196.

23.

Sunlight damage to cellular DNA: Focus on oxidatively generated lesions.

Schuch AP, Moreno NC, Schuch NJ, Menck CFM, Garcia CCM.

Free Radic Biol Med. 2017 Jun;107:110-124. doi: 10.1016/j.freeradbiomed.2017.01.029. Epub 2017 Jan 18. Review.

24.

The second of a series of articles for the 60th anniversary of the Brazilian Society of Genetics.

Salzano FM, Santos FR, Hartfelder K, Menck CF.

Genet Mol Biol. 2016 Oct-Dec;39(4):475. doi: 10.1590/1678-4685-GMB-2016-00040002. No abstract available.

25.

A genetic cluster of patients with variant xeroderma pigmentosum with two different founder mutations.

Munford V, Castro LP, Souto R, Lerner LK, Vilar JB, Quayle C, Asif H, Schuch AP, de Souza TA, Ienne S, Alves FIA, Moura LMS, Galante PAF, Camargo AA, Liboredo R, Pena SDJ, Sarasin A, Chaibub SC, Menck CFM.

Br J Dermatol. 2017 May;176(5):1270-1278. doi: 10.1111/bjd.15084. Epub 2017 Mar 22.

PMID:
27664908
26.

The first of a series of articles dedicated to the 60th anniversary of the Brazilian Society of Genetics (SBG).

Salzano FM, Santos FR, Hartfelder K, Menck CF.

Genet Mol Biol. 2016 Jul-Sep;39(3):301. doi: 10.1590/1678-4685-GMB-2016-00030002. No abstract available.

27.

The ubiquitin family meets the Fanconi anemia proteins.

Renaudin X, Koch Lerner L, Menck CF, Rosselli F.

Mutat Res Rev Mutat Res. 2016 Jul-Sep;769:36-46. doi: 10.1016/j.mrrev.2016.06.004. Epub 2016 Jun 23. Review.

PMID:
27543315
28.

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.

Rocha CR, Kajitani GS, Quinet A, Fortunato RS, Menck CF.

Oncotarget. 2016 Jul 26;7(30):48081-48092. doi: 10.18632/oncotarget.10129.

29.

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells.

Quinet A, Martins DJ, Vessoni AT, Biard D, Sarasin A, Stary A, Menck CF.

Nucleic Acids Res. 2016 Jul 8;44(12):5717-31. doi: 10.1093/nar/gkw280. Epub 2016 Apr 19.

30.

Mutation in PNKP presenting initially as axonal Charcot-Marie-Tooth disease.

Pedroso JL, Rocha CR, Macedo-Souza LI, De Mario V, Marques W Jr, Barsottini OG, Bulle Oliveira AS, Menck CF, Kok F.

Neurol Genet. 2015 Oct 22;1(4):e30. doi: 10.1212/NXG.0000000000000030. eCollection 2015 Dec.

31.

Microenvironment and autophagy cross-talk: Implications in cancer therapy.

Gomes LR, Vessoni AT, Menck CFM.

Pharmacol Res. 2016 May;107:300-307. doi: 10.1016/j.phrs.2016.03.031. Epub 2016 Mar 29. Review.

PMID:
27037157
32.

Evolutionary and Functional Relationships of the dha Regulon by Genomic Context Analysis.

Martins-Pinheiro M, Lima WC, Asif H, Oller CA, Menck CF.

PLoS One. 2016 Mar 3;11(3):e0150772. doi: 10.1371/journal.pone.0150772. eCollection 2016.

33.

XPC deficiency is related to APE1 and OGG1 expression and function.

de Melo JT, de Souza Timoteo AR, Lajus TB, Brandão JA, de Souza-Pinto NC, Menck CF, Campalans A, Radicella JP, Vessoni AT, Muotri AR, Agnez-Lima LF.

Mutat Res. 2016 Feb-Mar;784-785:25-33. doi: 10.1016/j.mrfmmm.2016.01.004. Epub 2016 Jan 16.

PMID:
26811994
34.

Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony.

Vessoni AT, Herai RH, Karpiak JV, Leal AM, Trujillo CA, Quinet A, Agnez Lima LF, Menck CF, Muotri AR.

Hum Mol Genet. 2016 Apr 1;25(7):1271-80. doi: 10.1093/hmg/ddw008. Epub 2016 Jan 10.

35.

Chloroquine-induced glioma cells death is associated with mitochondrial membrane potential loss, but not oxidative stress.

Vessoni AT, Quinet A, de Andrade-Lima LC, Martins DJ, Garcia CC, Rocha CR, Vieira DB, Menck CF.

Free Radic Biol Med. 2016 Jan;90:91-100. doi: 10.1016/j.freeradbiomed.2015.11.008. Epub 2015 Nov 11.

PMID:
26577174
36.

Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome.

Melo US, Macedo-Souza LI, Figueiredo T, Muotri AR, Gleeson JG, Coux G, Armas P, Calcaterra NB, Kitajima JP, Amorim S, Olávio TR, Griesi-Oliveira K, Coatti GC, Rocha CR, Martins-Pinheiro M, Menck CF, Zaki MS, Kok F, Zatz M, Santos S.

Hum Mol Genet. 2015 Dec 15;24(24):6877-85. doi: 10.1093/hmg/ddv388. Epub 2015 Sep 18.

37.

Mutation Research. DNA damage in chronic diseases and aging. Editorial.

Hojo ET, Menck CF, Salvadori DM.

Mutat Res. 2015 Jun;776:1. doi: 10.1016/j.mrfmmm.2015.05.008. No abstract available.

PMID:
26255933
38.

Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.

Rocha CR, Garcia CC, Vieira DB, Quinet A, de Andrade-Lima LC, Munford V, Belizário JE, Menck CF.

Cell Death Dis. 2015 Apr 16;6:e1727. doi: 10.1038/cddis.2015.101. No abstract available.

39.

DNA repair and recovery of RNA synthesis following exposure to ultraviolet light are delayed in long genes.

Andrade-Lima LC, Veloso A, Paulsen MT, Menck CF, Ljungman M.

Nucleic Acids Res. 2015 Mar 11;43(5):2744-56. doi: 10.1093/nar/gkv148. Epub 2015 Feb 26.

40.

Three-dimensional microenvironment confers enhanced sensitivity to doxorubicin by reducing p53-dependent induction of autophagy.

Gomes LR, Vessoni AT, Menck CF.

Oncogene. 2015 Oct 16;34(42):5329-40. doi: 10.1038/onc.2014.461. Epub 2015 Jan 26.

PMID:
25619836
41.

ATR suppresses apoptosis after UVB irradiation by controlling both translesion synthesis and alternative tolerance pathways.

Andrade-Lima LC, Andrade LN, Menck CF.

J Cell Sci. 2015 Jan 1;128(1):150-9. doi: 10.1242/jcs.161596. Epub 2014 Nov 6.

42.

Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.

Rocha CR, Garcia CC, Vieira DB, Quinet A, de Andrade-Lima LC, Munford V, Belizário JE, Menck CF.

Cell Death Dis. 2014 Oct 30;5:e1505. doi: 10.1038/cddis.2014.465. Erratum in: Cell Death Dis. 2015;6:e1727.

43.

Highly sensitive biological assay for determining the photoprotective efficacy of sunscreen.

Schuch AP, Moraes MC, Yagura T, Menck CF.

Environ Sci Technol. 2014 Oct 7;48(19):11584-90. doi: 10.1021/es503721a. Epub 2014 Sep 29.

44.

DNA repair diseases: What do they tell us about cancer and aging?

Menck CF, Munford V.

Genet Mol Biol. 2014 Mar;37(1 Suppl):220-33. Review.

45.

Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome.

Quinet A, Vessoni AT, Rocha CR, Gottifredi V, Biard D, Sarasin A, Menck CF, Stary A.

DNA Repair (Amst). 2014 Feb;14:27-38. doi: 10.1016/j.dnarep.2013.12.005. Epub 2013 Dec 28.

PMID:
24380689
46.

UVB-induced cell death signaling is associated with G1-S progression and transcription inhibition in primary human fibroblasts.

Ortolan TG, Menck CF.

PLoS One. 2013 Oct 14;8(10):e76936. doi: 10.1371/journal.pone.0076936. eCollection 2013.

47.

The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.

Beckedorff FC, Ayupe AC, Crocci-Souza R, Amaral MS, Nakaya HI, Soltys DT, Menck CF, Reis EM, Verjovski-Almeida S.

PLoS Genet. 2013;9(8):e1003705. doi: 10.1371/journal.pgen.1003705. Epub 2013 Aug 22.

48.

Autophagy and genomic integrity.

Vessoni AT, Filippi-Chiela EC, Menck CF, Lenz G.

Cell Death Differ. 2013 Nov;20(11):1444-54. doi: 10.1038/cdd.2013.103. Epub 2013 Aug 9. Review.

49.

The relative roles of DNA damage induced by UVA irradiation in human cells.

Cortat B, Garcia CC, Quinet A, Schuch AP, de Lima-Bessa KM, Menck CF.

Photochem Photobiol Sci. 2013 Aug;12(8):1483-95. doi: 10.1039/c3pp50023c.

PMID:
23824260
50.

Susceptibility to DNA damage as a molecular mechanism for non-syndromic cleft lip and palate.

Kobayashi GS, Alvizi L, Sunaga DY, Francis-West P, Kuta A, Almada BV, Ferreira SG, de Andrade-Lima LC, Bueno DF, Raposo-Amaral CE, Menck CF, Passos-Bueno MR.

PLoS One. 2013 Jun 12;8(6):e65677. doi: 10.1371/journal.pone.0065677. Print 2013.

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